Compile Data Set for Download or QSAR
Report error Found 22 Enz. Inhib. hit(s) with all data for entry = 50008663
TargetProthrombin(Human)
Novartis Horsham Research Center

Curated by ChEMBL
LigandPNGBDBM50073283(4-[(S)-1-Hydroxymethyl-2-(4-methoxy-phenyl)-ethyla...)
Affinity DataKi:  19nMAssay Description:In vitro inhibition of human thrombin.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProthrombin(Human)
Novartis Horsham Research Center

Curated by ChEMBL
LigandPNGBDBM50073283(4-[(S)-1-Hydroxymethyl-2-(4-methoxy-phenyl)-ethyla...)
Affinity DataKi:  19nMAssay Description:In vitro inhibition of human thrombin.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProthrombin(Human)
Novartis Horsham Research Center

Curated by ChEMBL
LigandPNGBDBM50073297(4-[(S)-1-Benzyl-2-(4-hydroxy-piperidin-1-yl)-ethyl...)
Affinity DataKi:  19nMAssay Description:In vitro inhibition of human thrombin.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProthrombin(Human)
Novartis Horsham Research Center

Curated by ChEMBL
LigandPNGBDBM50073298(4-((S)-1-Benzyl-2-morpholin-4-yl-ethylamino)-pyrid...)
Affinity DataKi:  22nMAssay Description:In vitro inhibition of human thrombin.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProthrombin(Human)
Novartis Horsham Research Center

Curated by ChEMBL
LigandPNGBDBM50073298(4-((S)-1-Benzyl-2-morpholin-4-yl-ethylamino)-pyrid...)
Affinity DataKi:  22nMAssay Description:In vitro inhibition of human thrombin.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProthrombin(Human)
Novartis Horsham Research Center

Curated by ChEMBL
LigandPNGBDBM50073294(4-((S)-1-Dimethylaminomethyl-2-phenyl-ethylamino)-...)
Affinity DataKi:  24nMAssay Description:In vitro inhibition of human thrombin.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProthrombin(Human)
Novartis Horsham Research Center

Curated by ChEMBL
LigandPNGBDBM50075870(4-[(S)-1-(2-Hydroxy-ethoxymethyl)-2-phenyl-ethylam...)
Affinity DataKi:  28nMAssay Description:In vitro inhibition of human thrombin.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProthrombin(Human)
Novartis Horsham Research Center

Curated by ChEMBL
LigandPNGBDBM50073295(4-((S)-1-Hydroxymethyl-2-phenyl-ethylamino)-pyridi...)
Affinity DataKi:  39nMAssay Description:In vitro inhibition of human thrombin.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProthrombin(Human)
Novartis Horsham Research Center

Curated by ChEMBL
LigandPNGBDBM50073295(4-((S)-1-Hydroxymethyl-2-phenyl-ethylamino)-pyridi...)
Affinity DataKi:  39nMAssay Description:In vitro inhibition of human thrombin.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProthrombin(Human)
Novartis Horsham Research Center

Curated by ChEMBL
LigandPNGBDBM50075873(4-[(S)-1-Hydroxymethyl-2-(4-methoxy-phenyl)-ethyla...)
Affinity DataKi:  40nMAssay Description:In vitro inhibition of human thrombin.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProthrombin(Human)
Novartis Horsham Research Center

Curated by ChEMBL
LigandPNGBDBM50073292(4-[(S)-1-(2-Hydroxy-ethoxymethyl)-2-phenyl-ethylam...)
Affinity DataKi:  49nMAssay Description:In vitro inhibition of human thrombin.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProthrombin(Human)
Novartis Horsham Research Center

Curated by ChEMBL
LigandPNGBDBM50073292(4-[(S)-1-(2-Hydroxy-ethoxymethyl)-2-phenyl-ethylam...)
Affinity DataKi:  49nMAssay Description:In vitro inhibition of human thrombin.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProthrombin(Human)
Novartis Horsham Research Center

Curated by ChEMBL
LigandPNGBDBM50075871(4-[(S)-1-(4-Hydroxy-piperidin-1-ylmethyl)-2-phenyl...)
Affinity DataKi:  61nMAssay Description:In vitro inhibition of human thrombin.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProthrombin(Human)
Novartis Horsham Research Center

Curated by ChEMBL
LigandPNGBDBM50075868(4-((S)-1-Morpholin-4-ylmethyl-2-phenyl-ethylamino)...)
Affinity DataKi:  62nMAssay Description:In vitro inhibition of human thrombin.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProthrombin(Human)
Novartis Horsham Research Center

Curated by ChEMBL
LigandPNGBDBM50075874(4-[(S)-1-Hydroxymethyl-2-(4-methoxy-phenyl)-ethyla...)
Affinity DataKi:  85nMAssay Description:In vitro inhibition of human thrombin.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProthrombin(Human)
Novartis Horsham Research Center

Curated by ChEMBL
LigandPNGBDBM50073301(4-((S)-1-Hydroxymethyl-2-phenyl-ethylamino)-pyridi...)
Affinity DataKi:  100nMAssay Description:In vitro inhibition of human thrombin.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProthrombin(Human)
Novartis Horsham Research Center

Curated by ChEMBL
LigandPNGBDBM50073281(4-((S)-1-Hydroxymethyl-2-phenyl-ethylamino)-pyridi...)
Affinity DataKi:  110nMAssay Description:In vitro inhibition of human thrombin.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProthrombin(Human)
Novartis Horsham Research Center

Curated by ChEMBL
LigandPNGBDBM50075875(4-((S)-1-Dimethylaminomethyl-2-phenyl-ethylamino)-...)
Affinity DataKi:  130nMAssay Description:In vitro inhibition of human thrombin.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProthrombin(Human)
Novartis Horsham Research Center

Curated by ChEMBL
LigandPNGBDBM50075875(4-((S)-1-Dimethylaminomethyl-2-phenyl-ethylamino)-...)
Affinity DataKi:  130nMAssay Description:In vitro inhibition of human thrombin.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProthrombin(Human)
Novartis Horsham Research Center

Curated by ChEMBL
LigandPNGBDBM50075869(4-[(S)-1-(2-Hydroxy-ethoxymethyl)-2-phenyl-ethylam...)
Affinity DataKi:  147nMAssay Description:In vitro inhibition of human thrombin.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProthrombin(Human)
Novartis Horsham Research Center

Curated by ChEMBL
LigandPNGBDBM50075869(4-[(S)-1-(2-Hydroxy-ethoxymethyl)-2-phenyl-ethylam...)
Affinity DataKi:  147nMAssay Description:In vitro inhibition of human thrombin.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProthrombin(Human)
Novartis Horsham Research Center

Curated by ChEMBL
LigandPNGBDBM50075872(4-[(S)-1-(2-Hydroxy-ethoxymethyl)-2-phenyl-ethylam...)
Affinity DataKi:  220nMAssay Description:In vitro inhibition of human thrombin.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed