Compile Data Set for Download or QSAR
Report error Found 36 Enz. Inhib. hit(s) with all data for entry = 50008575
TargetProstaglandin G/H synthase 1(Sheep)
Merck Frosst Canada

Curated by ChEMBL
LigandPNGBDBM50074933(alpha-Methyl-4-biphenyl-acetic acid | 2-biphenyl-4...)
Affinity DataIC50: 10nMAssay Description:In vitro inhibitory activity against Prostaglandin G/H synthase 1 in sheepMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Merck Frosst Canada

Curated by ChEMBL
LigandPNGBDBM50074922(2-(2-fluoro-[1,1'-biphenyl-4-yl])propanoic acid | ...)
Affinity DataIC50: 10nMAssay Description:In vitro inhibitory activity against Prostaglandin G/H synthase 2 (COX-2) in humanMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
Merck Frosst Canada

Curated by ChEMBL
LigandPNGBDBM50074922(2-(2-fluoro-[1,1'-biphenyl-4-yl])propanoic acid | ...)
Affinity DataIC50: 11nMAssay Description:In vitro inhibitory activity against Prostaglandin G/H synthase 1 in sheepMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Merck Frosst Canada

Curated by ChEMBL
LigandPNGBDBM50074932(2-(3'-Ethoxy-2-fluoro-biphenyl-4-yl)-propionic aci...)
Affinity DataIC50: 14nMAssay Description:In vitro inhibitory activity against Prostaglandin G/H synthase 2 (COX-2) in humanMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
Merck Frosst Canada

Curated by ChEMBL
LigandPNGBDBM50074932(2-(3'-Ethoxy-2-fluoro-biphenyl-4-yl)-propionic aci...)
Affinity DataIC50: 14nMAssay Description:In vitro inhibitory activity against Prostaglandin G/H synthase 1 in sheepMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Merck Frosst Canada

Curated by ChEMBL
LigandPNGBDBM50074933(alpha-Methyl-4-biphenyl-acetic acid | 2-biphenyl-4...)
Affinity DataIC50: 21nMAssay Description:In vitro inhibitory activity against Prostaglandin G/H synthase 2 (COX-2) in humanMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
Merck Frosst Canada

Curated by ChEMBL
LigandPNGBDBM50074926(2-(2-Fluoro-3',5'-dimethoxy-biphenyl-4-yl)-propion...)
Affinity DataIC50: 63nMAssay Description:In vitro inhibitory activity against Prostaglandin G/H synthase 1 in sheepMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Merck Frosst Canada

Curated by ChEMBL
LigandPNGBDBM50074926(2-(2-Fluoro-3',5'-dimethoxy-biphenyl-4-yl)-propion...)
Affinity DataIC50: 70nMAssay Description:In vitro inhibitory activity against Prostaglandin G/H synthase 2 (COX-2) in humanMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Merck Frosst Canada

Curated by ChEMBL
LigandPNGBDBM50029593(CHEMBL7162 | NS398 | NS-398 | N-(2-Cyclohexyloxy-4...)
Affinity DataIC50: 90nMAssay Description:In vitro inhibitory activity against Prostaglandin G/H synthase 2 (COX-2) in humanMore data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetProstaglandin G/H synthase 2(Human)
Merck Frosst Canada

Curated by ChEMBL
LigandPNGBDBM50074927(2-(3',5'-Diethoxy-2-fluoro-biphenyl-4-yl)-propioni...)
Affinity DataIC50: 100nMAssay Description:In vitro inhibitory activity against Prostaglandin G/H synthase 2 (COX-2) in humanMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
Merck Frosst Canada

Curated by ChEMBL
LigandPNGBDBM50074934(2-[4-(1H-Indol-5-yl)-phenyl]-propionic acid | CHEM...)
Affinity DataIC50: 100nMAssay Description:In vitro inhibitory activity against Prostaglandin G/H synthase 1 in sheepMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Merck Frosst Canada

Curated by ChEMBL
LigandPNGBDBM50074936(2-(3'-Allyl-biphenyl-4-yl)-propionic acid | CHEMBL...)
Affinity DataIC50: 150nMAssay Description:In vitro inhibitory activity against Prostaglandin G/H synthase 2 (COX-2) in humanMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Merck Frosst Canada

Curated by ChEMBL
LigandPNGBDBM50029600(CHEMBL42485 | 5-bromo-2-(4-fluorophenyl)-3-(4-(met...)
Affinity DataIC50: 190nMAssay Description:In vitro inhibitory activity against Prostaglandin G/H synthase 2 (COX-2) in humanMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Merck Frosst Canada

Curated by ChEMBL
LigandPNGBDBM50074923(2-[4-(5-Vinyl-pyridin-3-yl)-phenyl]-propionic acid...)
Affinity DataIC50: 190nMAssay Description:In vitro inhibitory activity against Prostaglandin G/H synthase 2 (COX-2) in humanMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
Merck Frosst Canada

Curated by ChEMBL
LigandPNGBDBM50074923(2-[4-(5-Vinyl-pyridin-3-yl)-phenyl]-propionic acid...)
Affinity DataIC50: 190nMAssay Description:In vitro inhibitory activity against Prostaglandin G/H synthase 1 in sheepMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Merck Frosst Canada

Curated by ChEMBL
LigandPNGBDBM50074934(2-[4-(1H-Indol-5-yl)-phenyl]-propionic acid | CHEM...)
Affinity DataIC50: 190nMAssay Description:In vitro inhibitory activity against Prostaglandin G/H synthase 2 (COX-2) in humanMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Merck Frosst Canada

Curated by ChEMBL
LigandPNGBDBM50074928(2-[4-(2-Methyl-1H-indol-5-yl)-phenyl]-propionic ac...)
Affinity DataIC50: 230nMAssay Description:In vitro inhibitory activity against Prostaglandin G/H synthase 2 (COX-2) in humanMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Merck Frosst Canada

Curated by ChEMBL
LigandPNGBDBM50074930(2-(3',5'-Diethoxy-biphenyl-4-yl)-propionic acid | ...)
Affinity DataIC50: 320nMAssay Description:In vitro inhibitory activity against Prostaglandin G/H synthase 2 (COX-2) in humanMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Merck Frosst Canada

Curated by ChEMBL
LigandPNGBDBM50074924(2-(3'-Ethylsulfanyl-biphenyl-4-yl)-propionic acid ...)
Affinity DataIC50: 330nMAssay Description:In vitro inhibitory activity against Prostaglandin G/H synthase 2 (COX-2) in humanMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Merck Frosst Canada

Curated by ChEMBL
LigandPNGBDBM50074935(2-{4-[((E)-5-Propenyl)-pyridin-3-yl]-phenyl}-propi...)
Affinity DataIC50: 670nMAssay Description:In vitro inhibitory activity against Prostaglandin G/H synthase 2 (COX-2) in humanMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Merck Frosst Canada

Curated by ChEMBL
LigandPNGBDBM50074925(2-(3'-Vinyl-biphenyl-4-yl)-propionic acid | CHEMBL...)
Affinity DataIC50: 730nMAssay Description:In vitro inhibitory activity against Prostaglandin G/H synthase 2 (COX-2) in humanMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
Merck Frosst Canada

Curated by ChEMBL
LigandPNGBDBM50074925(2-(3'-Vinyl-biphenyl-4-yl)-propionic acid | CHEMBL...)
Affinity DataIC50: 1.30E+3nMAssay Description:In vitro inhibitory activity against Prostaglandin G/H synthase 1 in sheepMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
Merck Frosst Canada

Curated by ChEMBL
LigandPNGBDBM50074936(2-(3'-Allyl-biphenyl-4-yl)-propionic acid | CHEMBL...)
Affinity DataIC50: 1.40E+3nMAssay Description:In vitro inhibitory activity against Prostaglandin G/H synthase 1 in sheepMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Merck Frosst Canada

Curated by ChEMBL
LigandPNGBDBM50074929(2-(3'-Ethyl-biphenyl-4-yl)-propionic acid | CHEMBL...)
Affinity DataIC50: 2.40E+3nMAssay Description:In vitro inhibitory activity against Prostaglandin G/H synthase 2 (COX-2) in humanMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
Merck Frosst Canada

Curated by ChEMBL
LigandPNGBDBM50074924(2-(3'-Ethylsulfanyl-biphenyl-4-yl)-propionic acid ...)
Affinity DataIC50: 3.10E+3nMAssay Description:In vitro inhibitory activity against Prostaglandin G/H synthase 1 in sheepMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
Merck Frosst Canada

Curated by ChEMBL
LigandPNGBDBM50029600(CHEMBL42485 | 5-bromo-2-(4-fluorophenyl)-3-(4-(met...)
Affinity DataIC50: 4.60E+3nMAssay Description:In vitro inhibitory activity against Prostaglandin G/H synthase 1 in sheepMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
Merck Frosst Canada

Curated by ChEMBL
LigandPNGBDBM50074929(2-(3'-Ethyl-biphenyl-4-yl)-propionic acid | CHEMBL...)
Affinity DataIC50: 5.80E+3nMAssay Description:In vitro inhibitory activity against Prostaglandin G/H synthase 1 in sheepMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
Merck Frosst Canada

Curated by ChEMBL
LigandPNGBDBM50074927(2-(3',5'-Diethoxy-2-fluoro-biphenyl-4-yl)-propioni...)
Affinity DataIC50: 7.70E+3nMAssay Description:In vitro inhibitory activity against Prostaglandin G/H synthase 1 in sheepMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
Merck Frosst Canada

Curated by ChEMBL
LigandPNGBDBM50074928(2-[4-(2-Methyl-1H-indol-5-yl)-phenyl]-propionic ac...)
Affinity DataIC50: 1.05E+4nMAssay Description:In vitro inhibitory activity against Prostaglandin G/H synthase 1 in sheepMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
Merck Frosst Canada

Curated by ChEMBL
LigandPNGBDBM50074931(2-(2-Fluoro-3'-isopropyl-biphenyl-4-yl)-propionic ...)
Affinity DataIC50: 1.50E+4nMAssay Description:In vitro inhibitory activity against Prostaglandin G/H synthase 1 in sheepMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
Merck Frosst Canada

Curated by ChEMBL
LigandPNGBDBM50074937(2-(2-Fluoro-3',5'-dimethyl-biphenyl-4-yl)-propioni...)
Affinity DataIC50: 1.50E+4nMAssay Description:In vitro inhibitory activity against Prostaglandin G/H synthase 1 in sheepMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
Merck Frosst Canada

Curated by ChEMBL
LigandPNGBDBM50074935(2-{4-[((E)-5-Propenyl)-pyridin-3-yl]-phenyl}-propi...)
Affinity DataIC50: 1.55E+4nMAssay Description:In vitro inhibitory activity against Prostaglandin G/H synthase 1 in sheepMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Merck Frosst Canada

Curated by ChEMBL
LigandPNGBDBM50074937(2-(2-Fluoro-3',5'-dimethyl-biphenyl-4-yl)-propioni...)
Affinity DataIC50: 1.90E+4nMAssay Description:In vitro inhibitory activity against Prostaglandin G/H synthase 2 (COX-2) in humanMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
Merck Frosst Canada

Curated by ChEMBL
LigandPNGBDBM50074930(2-(3',5'-Diethoxy-biphenyl-4-yl)-propionic acid | ...)
Affinity DataIC50: 2.50E+4nMAssay Description:In vitro inhibitory activity against Prostaglandin G/H synthase 1 in sheepMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
Merck Frosst Canada

Curated by ChEMBL
LigandPNGBDBM50029593(CHEMBL7162 | NS398 | NS-398 | N-(2-Cyclohexyloxy-4...)
Affinity DataIC50: 3.70E+4nMAssay Description:In vitro inhibitory activity against Prostaglandin G/H synthase 1 in sheepMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Merck Frosst Canada

Curated by ChEMBL
LigandPNGBDBM50074931(2-(2-Fluoro-3'-isopropyl-biphenyl-4-yl)-propionic ...)
Affinity DataIC50: 1.00E+5nMAssay Description:In vitro inhibitory activity against Prostaglandin G/H synthase 2 (COX-2) in humanMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed