Compile Data Set for Download or QSAR
Report error Found 39 Enz. Inhib. hit(s) with all data for entry = 50008554
TargetIntegrin alpha-4/beta-1(Human)
Biogen

Curated by ChEMBL
LigandPNGBDBM50074659((S)-2-[(S)-3-Carboxy-2-((S)-4-methyl-2-{2-[4-(3-o-...)
Affinity DataIC50: 0.600nMAssay Description:Inhibition of integrin alpha4-beta1 binding to VCAM-IgMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-1(Human)
Biogen

Curated by ChEMBL
LigandPNGBDBM50074661((S)-1-{(S)-2-[(S)-3-Carboxy-2-((S)-4-methyl-2-{2-[...)
Affinity DataIC50: 1nMAssay Description:Inhibition of integrin alpha4-beta1 binding to VCAM-IgMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-1(Human)
Biogen

Curated by ChEMBL
LigandPNGBDBM50074664((S)-N-[(S)-1-((S)-2-Carbamoyl-pyrrolidine-1-carbon...)
Affinity DataIC50: 1nMAssay Description:Inhibition of integrin alpha4-beta1 binding to VCAM-IgMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-1(Human)
Biogen

Curated by ChEMBL
LigandPNGBDBM50422305(CHEMBL1791268)
Affinity DataIC50: 1nMAssay Description:Inhibition of integrin alpha4-beta1 binding to VCAM-IgMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-1(Human)
Biogen

Curated by ChEMBL
LigandPNGBDBM50074660((S)-2-[(S)-3-Carboxy-2-((S)-4-methyl-2-{2-[4-(3-ph...)
Affinity DataIC50: 3nMAssay Description:Inhibition of integrin alpha4-beta1 binding to VCAM-IgMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-1(Human)
Biogen

Curated by ChEMBL
LigandPNGBDBM50074661((S)-1-{(S)-2-[(S)-3-Carboxy-2-((S)-4-methyl-2-{2-[...)
Affinity DataIC50: 4nMAssay Description:Inhibition of integrin alpha4-beta1 adhesion to Jurkat cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-1(Human)
Biogen

Curated by ChEMBL
LigandPNGBDBM50074658((S)-1-{(S)-2-[(S)-2-((S)-6-(6-Amino-hexanoylamino)...)
Affinity DataIC50: 4nMAssay Description:Inhibition of integrin alpha4-beta1 binding to VCAM-IgMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-1(Human)
Biogen

Curated by ChEMBL
LigandPNGBDBM50422305(CHEMBL1791268)
Affinity DataIC50: 5nMAssay Description:Inhibition of integrin alpha4-beta1 adhesion to Jurkat cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-1(Human)
Biogen

Curated by ChEMBL
LigandPNGBDBM50074659((S)-2-[(S)-3-Carboxy-2-((S)-4-methyl-2-{2-[4-(3-o-...)
Affinity DataIC50: 6nMAssay Description:Inhibition of integrin alpha4-beta1 adhesion to Jurkat cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-1(Human)
Biogen

Curated by ChEMBL
LigandPNGBDBM50074664((S)-N-[(S)-1-((S)-2-Carbamoyl-pyrrolidine-1-carbon...)
Affinity DataIC50: 8nMAssay Description:Inhibition of integrin alpha4-beta1 adhesion to Jurkat cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-1(Human)
Biogen

Curated by ChEMBL
LigandPNGBDBM50074668((S)-2-((S)-4-Methyl-2-{2-[4-(3-o-tolyl-ureido)-phe...)
Affinity DataIC50: 18nMAssay Description:Inhibition of integrin alpha4-beta1 binding to VCAM-IgMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-1(Human)
Biogen

Curated by ChEMBL
LigandPNGBDBM50074658((S)-1-{(S)-2-[(S)-2-((S)-6-(6-Amino-hexanoylamino)...)
Affinity DataIC50: 20nMAssay Description:Inhibition of integrin alpha4-beta1 adhesion to Jurkat cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-1(Human)
Biogen

Curated by ChEMBL
LigandPNGBDBM50074660((S)-2-[(S)-3-Carboxy-2-((S)-4-methyl-2-{2-[4-(3-ph...)
Affinity DataIC50: 30nMAssay Description:Inhibition of integrin alpha4-beta1 adhesion to Jurkat cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-1(Human)
Biogen

Curated by ChEMBL
LigandPNGBDBM50074666((S)-2-((S)-2-{(S)-2-[2-(4-Benzyloxycarbonylamino-p...)
Affinity DataIC50: 30nMAssay Description:Inhibition of integrin alpha4-beta1 binding to VCAM-IgMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-1(Human)
Biogen

Curated by ChEMBL
LigandPNGBDBM50074668((S)-2-((S)-4-Methyl-2-{2-[4-(3-o-tolyl-ureido)-phe...)
Affinity DataIC50: 68nMAssay Description:Inhibition of integrin alpha4-beta1 adhesion to Jurkat cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-1(Human)
Biogen

Curated by ChEMBL
LigandPNGBDBM50074666((S)-2-((S)-2-{(S)-2-[2-(4-Benzyloxycarbonylamino-p...)
Affinity DataIC50: 200nMAssay Description:Inhibition of integrin alpha4-beta1 adhesion to Jurkat cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-1(Human)
Biogen

Curated by ChEMBL
LigandPNGBDBM50074667((S)-2-((S)-2-{(S)-2-[2-(4-Benzoylamino-phenyl)-ace...)
Affinity DataIC50: 295nMAssay Description:Inhibition of integrin alpha4-beta1 binding to VCAM-IgMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-1(Human)
Biogen

Curated by ChEMBL
LigandPNGBDBM50074665((S)-2-((S)-3-Carboxy-2-{(S)-2-[2-(4-hydroxy-phenyl...)
Affinity DataIC50: 430nMAssay Description:Inhibition of integrin alpha4-beta1 binding to VCAM-IgMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-1(Human)
Biogen

Curated by ChEMBL
LigandPNGBDBM50074669((S)-2-[(S)-3-Carboxy-2-((S)-4-methyl-2-phenylacety...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of integrin alpha4-beta1 binding to VCAM-IgMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-7(Human)
Biogen

Curated by ChEMBL
LigandPNGBDBM50074661((S)-1-{(S)-2-[(S)-3-Carboxy-2-((S)-4-methyl-2-{2-[...)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of integrin alpha4-beta7 adhesion to JY cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-1(Human)
Biogen

Curated by ChEMBL
LigandPNGBDBM50074667((S)-2-((S)-2-{(S)-2-[2-(4-Benzoylamino-phenyl)-ace...)
Affinity DataIC50: 3.25E+3nMAssay Description:Inhibition of integrin alpha4-beta1 adhesion to Jurkat cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-1(Human)
Biogen

Curated by ChEMBL
LigandPNGBDBM50074665((S)-2-((S)-3-Carboxy-2-{(S)-2-[2-(4-hydroxy-phenyl...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of integrin alpha4-beta1 adhesion to Jurkat cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-7(Human)
Biogen

Curated by ChEMBL
LigandPNGBDBM50074659((S)-2-[(S)-3-Carboxy-2-((S)-4-methyl-2-{2-[4-(3-o-...)
Affinity DataIC50: 8.00E+3nMAssay Description:Inhibition of integrin alpha4-beta7 adhesion to JY cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-1(Human)
Biogen

Curated by ChEMBL
LigandPNGBDBM50074662((S)-2-((S)-2-{(S)-2-[(S)-2-Amino-3-(4-hydroxy-phen...)
Affinity DataIC50: 1.26E+4nMAssay Description:Inhibition of integrin alpha4-beta1 binding to VCAM-IgMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-1(Human)
Biogen

Curated by ChEMBL
LigandPNGBDBM50074669((S)-2-[(S)-3-Carboxy-2-((S)-4-methyl-2-phenylacety...)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of integrin alpha4-beta1 adhesion to Jurkat cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50074659((S)-2-[(S)-3-Carboxy-2-((S)-4-methyl-2-{2-[4-(3-o-...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of ICAM-1 transfected CHO cell adhesion to integrin alphaL-beta2 of human JY cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-1(Human)
Biogen

Curated by ChEMBL
LigandPNGBDBM50074662((S)-2-((S)-2-{(S)-2-[(S)-2-Amino-3-(4-hydroxy-phen...)
Affinity DataIC50: 5.10E+4nMAssay Description:Inhibition of integrin alpha4-beta1 adhesion to Jurkat cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-7(Human)
Biogen

Curated by ChEMBL
LigandPNGBDBM50074668((S)-2-((S)-4-Methyl-2-{2-[4-(3-o-tolyl-ureido)-phe...)
Affinity DataIC50: 5.90E+4nMAssay Description:Inhibition of integrin alpha4-beta7 adhesion to JY cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-1(Human)
Biogen

Curated by ChEMBL
LigandPNGBDBM50074670((S)-2-{(S)-2-[(S)-2-((2S,3S)-2-Amino-3-methyl-pent...)
Affinity DataIC50: 6.60E+4nMAssay Description:Inhibition of integrin alpha4-beta1 binding to VCAM-IgMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-5/beta-1(Human)
Biogen

Curated by ChEMBL
LigandPNGBDBM50074668((S)-2-((S)-4-Methyl-2-{2-[4-(3-o-tolyl-ureido)-phe...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of integrin alpha5-beta1 adhesion to K562 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-5/beta-1(Human)
Biogen

Curated by ChEMBL
LigandPNGBDBM50074659((S)-2-[(S)-3-Carboxy-2-((S)-4-methyl-2-{2-[4-(3-o-...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of integrin alpha5-beta1 adhesion to K562 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Biogen

Curated by ChEMBL
LigandPNGBDBM50074661((S)-1-{(S)-2-[(S)-3-Carboxy-2-((S)-4-methyl-2-{2-[...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of integrin alphaIIb-beta3 adhesion to human citreated plateletsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Biogen

Curated by ChEMBL
LigandPNGBDBM50074659((S)-2-[(S)-3-Carboxy-2-((S)-4-methyl-2-{2-[4-(3-o-...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of integrin alphaIIb-beta3 adhesion to human citreated plateletsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-1(Human)
Biogen

Curated by ChEMBL
LigandPNGBDBM50074659((S)-2-[(S)-3-Carboxy-2-((S)-4-methyl-2-{2-[4-(3-o-...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of integrin alpha1-beta1 adhesion using K562 cells expressing alpha-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50074668((S)-2-((S)-4-Methyl-2-{2-[4-(3-o-tolyl-ureido)-phe...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of ICAM-1 transfected CHO cell adhesion to integrin alphaL-beta2 of human JY cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-5/beta-1(Human)
Biogen

Curated by ChEMBL
LigandPNGBDBM50074661((S)-1-{(S)-2-[(S)-3-Carboxy-2-((S)-4-methyl-2-{2-[...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of integrin alpha5-beta1 adhesion to K562 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50074661((S)-1-{(S)-2-[(S)-3-Carboxy-2-((S)-4-methyl-2-{2-[...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of ICAM-1 transfected CHO cell adhesion to integrin alphaL-beta2 of human JY cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Biogen

Curated by ChEMBL
LigandPNGBDBM50074668((S)-2-((S)-4-Methyl-2-{2-[4-(3-o-tolyl-ureido)-phe...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of integrin alphaIIb-beta3 adhesion to human citreated plateletsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-1(Human)
Biogen

Curated by ChEMBL
LigandPNGBDBM50074670((S)-2-{(S)-2-[(S)-2-((2S,3S)-2-Amino-3-methyl-pent...)
Affinity DataIC50: 1.75E+5nMAssay Description:Inhibition of integrin alpha4-beta1 adhesion to Jurkat cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed