Compile Data Set for Download or QSAR
Report error Found 62 of ic50 data for polymerid = 9641
TargetHistone-lysine N-methyltransferase NSD3(Human)
Daiichi Sankyo Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50590375(CHEMBL5187396)
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetHistone-lysine N-methyltransferase NSD3(Human)
Daiichi Sankyo Co., Ltd

Curated by ChEMBL
LigandPNGBDBM588052((2R)-7-chloro-2-[trans-4-(dimethylamino)cyclohexyl...)
Ligand InfoPurchaseSimilars
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetHistone-lysine N-methyltransferase NSD3(Human)
Daiichi Sankyo Co., Ltd

Curated by ChEMBL
LigandPNGBDBM567959((R)-1-((R)-3-amino-1-(4-((6-amino-9H-purin-9-yl)me...)
Affinity DataIC50: 1nMAssay Description:Inhibition of NSD3 degradation in human KMS-11 cells assessed as reduction in H3K36me2 levels by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetHistone-lysine N-methyltransferase NSD3(Human)
Daiichi Sankyo Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50627886(CHEMBL5438312)
Affinity DataIC50: 1nMAssay Description:Inhibition of NSD3 degradation in human KMS-11 cells assessed as reduction in H3K36me2 levels by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetHistone-lysine N-methyltransferase NSD3(Human)
Daiichi Sankyo Co., Ltd

Curated by ChEMBL
LigandPNGBDBM567822(US11420970, Example 23)
Affinity DataIC50: 1nMAssay Description:Inhibition of NSD3 degradation in human KMS-11 cells assessed as reduction in H3K36me2 levels by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetHistone-lysine N-methyltransferase NSD3(Human)
Daiichi Sankyo Co., Ltd

Curated by ChEMBL
LigandPNGBDBM567825(US11420970, Example 26)
Affinity DataIC50: 1nMAssay Description:Inhibition of NSD3 degradation in human KMS-11 cells assessed as reduction in H3K36me2 levels by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetHistone-lysine N-methyltransferase NSD3(Human)
Daiichi Sankyo Co., Ltd

Curated by ChEMBL
LigandPNGBDBM567828(US11420970, Example 29)
Affinity DataIC50: 1nMAssay Description:Inhibition of NSD3 degradation in human KMS-11 cells assessed as reduction in H3K36me2 levels by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetHistone-lysine N-methyltransferase NSD3(Human)
Daiichi Sankyo Co., Ltd

Curated by ChEMBL
LigandPNGBDBM567831(US11420970, Example 32)
Affinity DataIC50: 1nMAssay Description:Inhibition of NSD3 degradation in human KMS-11 cells assessed as reduction in H3K36me2 levels by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetHistone-lysine N-methyltransferase NSD3(Human)
Daiichi Sankyo Co., Ltd

Curated by ChEMBL
LigandPNGBDBM567955((R)-1-((R)-3-amino-1-(4-((6-amino-9H-purin-9-yl)me...)
Affinity DataIC50: 1nMAssay Description:Inhibition of NSD3 degradation in human KMS-11 cells assessed as reduction in H3K36me2 levels by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetHistone-lysine N-methyltransferase NSD3(Human)
Daiichi Sankyo Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50365463(CHEMBL1232461)
Affinity DataIC50: 100nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetHistone-lysine N-methyltransferase NSD3(Human)
Daiichi Sankyo Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50594308(CHEMBL5186268)
Affinity DataIC50: 110nMAssay Description:Antagonist activity against recombinant human GST-tagged NSD3 PWWP1 domain (247 to 398 residues) expressed in Escherichia coli BL21(DE3) incubated fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetHistone-lysine N-methyltransferase NSD3(Human)
Daiichi Sankyo Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50555101(CHEMBL4778517)
Affinity DataIC50: 200nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetHistone-lysine N-methyltransferase NSD3(Human)
Daiichi Sankyo Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50555101(CHEMBL4778517)
Affinity DataIC50: 200nMAssay Description:Inhibition of NSD3 PWWP1 domain (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetHistone-lysine N-methyltransferase NSD3(Human)
Daiichi Sankyo Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50555101(CHEMBL4778517)
Affinity DataIC50: 200nMAssay Description:Antagonist activity against recombinant human GST-tagged NSD3 PWWP1 domain (247 to 398 residues) expressed in Escherichia coli BL21(DE3) incubated fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetHistone-lysine N-methyltransferase NSD3(Human)
Daiichi Sankyo Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50555101(CHEMBL4778517)
Affinity DataIC50: 200nMAssay Description:Inhibition of GST-tagged NSD3-PWWP1 domain (247 to 398 residues) (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetHistone-lysine N-methyltransferase NSD3(Human)
Daiichi Sankyo Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50608080(CHEMBL5277519)
Affinity DataIC50: 203nMAssay Description:Antagonist activity against recombinant human GST-tagged NSD3 PWWP1 domain (247 to 398 residues) incubated for 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetHistone-lysine N-methyltransferase NSD3(Human)
Daiichi Sankyo Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50608082(CHEMBL5265919)
Affinity DataIC50: 203nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetHistone-lysine N-methyltransferase NSD3(Human)
Daiichi Sankyo Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50106497(NSC-663284 | 6-Chloro-7-(2-morpholin-4-yl-ethylami...)
Affinity DataIC50: 260nMAssay Description:Inhibition of N-terminal GST-fused recombinant human NSD3 (1021 to 1322 residues) expressed in Escherichia coli using SAM as substrate preincubated f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetHistone-lysine N-methyltransferase NSD3(Human)
Daiichi Sankyo Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50106497(NSC-663284 | 6-Chloro-7-(2-morpholin-4-yl-ethylami...)
Affinity DataIC50: 340nMAssay Description:Inhibition of NSD3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetHistone-lysine N-methyltransferase NSD3(Human)
Daiichi Sankyo Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50637608(CHEMBL5558815)
Affinity DataIC50: 410nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetHistone-lysine N-methyltransferase NSD3(Human)
Daiichi Sankyo Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50616733(CHEMBL5422549)
Affinity DataIC50: 750nMAssay Description:Inhibition of NSD3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetHistone-lysine N-methyltransferase NSD3(Human)
Daiichi Sankyo Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50637602(CHEMBL5564764)
Affinity DataIC50: 800nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetHistone-lysine N-methyltransferase NSD3(Human)
Daiichi Sankyo Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50637598(CHEMBL5542461)
Affinity DataIC50: 840nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetHistone-lysine N-methyltransferase NSD3(Human)
Daiichi Sankyo Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50637597(CHEMBL5560302)
Affinity DataIC50: 1.09E+3nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetHistone-lysine N-methyltransferase NSD3(Human)
Daiichi Sankyo Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50162774(ABT-199 | Venetoclax | US11420968, Example ABT-199)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of N-terminal GST-fused recombinant human NSD3 (1021 to 1322 residues) expressed in Escherichia coli using SAM as substrate preincubated f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetHistone-lysine N-methyltransferase NSD3(Human)
Daiichi Sankyo Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50629735(CHEMBL5427539)
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of NSD3 PWWP1 domain (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetHistone-lysine N-methyltransferase NSD3(Human)
Daiichi Sankyo Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50637609(CHEMBL5564607)
Affinity DataIC50: 2.23E+3nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetHistone-lysine N-methyltransferase NSD3(Human)
Daiichi Sankyo Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50388091(CHEMBL2058156)
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of N-terminal GST-fused recombinant human NSD3 (1021 to 1322 residues) expressed in Escherichia coli using SAM as substrate preincubated f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetHistone-lysine N-methyltransferase NSD3(Human)
Daiichi Sankyo Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50637611(CHEMBL5557059)
Affinity DataIC50: 2.56E+3nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetHistone-lysine N-methyltransferase NSD3(Human)
Daiichi Sankyo Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50637604(CHEMBL5560651)
Affinity DataIC50: 2.80E+3nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetHistone-lysine N-methyltransferase NSD3(Human)
Daiichi Sankyo Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50637610(CHEMBL5567841)
Affinity DataIC50: 2.91E+3nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetHistone-lysine N-methyltransferase NSD3(Human)
Daiichi Sankyo Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50627878(CHEMBL5402803)
Affinity DataIC50: 3.20E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetHistone-lysine N-methyltransferase NSD3(Human)
Daiichi Sankyo Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50629733(CHEMBL5414580)
Affinity DataIC50: 3.20E+3nMAssay Description:Inhibition of N-terminal His-TEV-tagged human NSD3 (1054 to 1285 residues ) expressed in Escherichia coli using 3[H] SAM as substrate measured after ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetHistone-lysine N-methyltransferase NSD3(Human)
Daiichi Sankyo Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50324210((3S,3aR)-2-(3-Chloro-4-cyanophenyl)-3-cyclopentyl-...)
Affinity DataIC50: 3.20E+3nMAssay Description:Inhibition of N-terminal GST-fused recombinant human NSD3 (1021 to 1322 residues) expressed in Escherichia coli using SAM as substrate preincubated f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetHistone-lysine N-methyltransferase NSD3(Human)
Daiichi Sankyo Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50315537(chaetocin | CHEMBL1089316)
Affinity DataIC50: 3.20E+3nMAssay Description:Inhibition of N-terminal GST-fused recombinant human NSD3 (1021 to 1322 residues) expressed in Escherichia coli using SAM as substrate preincubated f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetHistone-lysine N-methyltransferase NSD3(Human)
Daiichi Sankyo Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50627878(CHEMBL5402803)
Affinity DataIC50: 3.20E+3nMAssay Description:Inhibition of NSD3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetHistone-lysine N-methyltransferase NSD3(Human)
Daiichi Sankyo Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50637605(CHEMBL5559774)
Affinity DataIC50: 3.74E+3nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetHistone-lysine N-methyltransferase NSD3(Human)
Daiichi Sankyo Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50637600(CHEMBL5567265)
Affinity DataIC50: 4.93E+3nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetHistone-lysine N-methyltransferase NSD3(Human)
Daiichi Sankyo Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50629734(CHEMBL5431913)
Affinity DataIC50: 5.20E+3nMAssay Description:Inhibition of NSD3 PWWP1 domain (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetHistone-lysine N-methyltransferase NSD3(Human)
Daiichi Sankyo Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50637607(CHEMBL5564456)
Affinity DataIC50: 6.75E+3nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetHistone-lysine N-methyltransferase NSD3(Human)
Daiichi Sankyo Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50315537(chaetocin | CHEMBL1089316)
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of human NSD3 overexpressed in Escherichia coli BL21(DE3) using nucleosome as substrate by SPA analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetHistone-lysine N-methyltransferase NSD3(Human)
Daiichi Sankyo Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50179360(CHEMBL3040216)
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of human NSD3 overexpressed in Escherichia coli BL21(DE3) using nucleosome as substrate by SPA analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetHistone-lysine N-methyltransferase NSD3(Human)
Daiichi Sankyo Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50637596(CHEMBL5532318)
Affinity DataIC50: 1.33E+4nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetHistone-lysine N-methyltransferase NSD3(Human)
Daiichi Sankyo Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50637593(CHEMBL1361969)
Affinity DataIC50: 1.38E+4nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetHistone-lysine N-methyltransferase NSD3(Human)
Daiichi Sankyo Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50608077(CHEMBL5270736)
Affinity DataIC50: 1.43E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetHistone-lysine N-methyltransferase NSD3(Human)
Daiichi Sankyo Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50637594(CHEMBL1567342)
Affinity DataIC50: 1.43E+4nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetHistone-lysine N-methyltransferase NSD3(Human)
Daiichi Sankyo Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50637599(CHEMBL5560642)
Affinity DataIC50: 1.54E+4nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetHistone-lysine N-methyltransferase NSD3(Human)
Daiichi Sankyo Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50643526(CHEMBL5575577)
Affinity DataIC50: 2.00E+4nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetHistone-lysine N-methyltransferase NSD3(Human)
Daiichi Sankyo Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50643520(CHEMBL5570019)
Affinity DataIC50: 2.00E+4nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetHistone-lysine N-methyltransferase NSD3(Human)
Daiichi Sankyo Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50637595(CHEMBL1606717)
Affinity DataIC50: 3.22E+4nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
Displayed 1 to 50 (of 62 total ) | Next | Last >>
Jump to: