Compile Data Set for Download or QSAR
Report error Found 1154 of ic50 data for polymerid = 9556
TargetPolycomb protein EED(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50540012(CHEMBL4637520)
Affinity DataIC50: 0.200nMAssay Description:Inhibition of EED ( 1 to 441 residues) (unknown origin) pre-incubated for 15 mins before biotin-H3K27me3 (19 to 33 residues) addition and further inc...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPolycomb protein EED(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50540013(CHEMBL4637096)
Affinity DataIC50: 0.200nMAssay Description:Inhibition of EED ( 1 to 441 residues) (unknown origin) pre-incubated for 15 mins before biotin-H3K27me3 (19 to 33 residues) addition and further inc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetPolycomb protein EED(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50573351(CHEMBL4870920)
Affinity DataIC50: 0.200nMAssay Description:Inhibition of biotinylated H3K27Me3 peptide (19 to 33 residues) binding to His-tagged EED (1 to 441 residues) (unknown origin) preincubated for 15 mi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetPolycomb protein EED(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50540014(CHEMBL4638412)
Affinity DataIC50: 0.300nMAssay Description:Inhibition of EED ( 1 to 441 residues) (unknown origin) pre-incubated for 15 mins before biotin-H3K27me3 (19 to 33 residues) addition and further inc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetPolycomb protein EED(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM451070(US10676479, Example 100 | N-((5-fluoro-2,3-dihydro...)
Affinity DataIC50: 0.400nMAssay Description:Inhibition of EED ( 1 to 441 residues) (unknown origin) pre-incubated for 15 mins before biotin-H3K27me3 (19 to 33 residues) addition and further inc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetPolycomb protein EED(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50540009(CHEMBL4643880)
Affinity DataIC50: 0.400nMAssay Description:Inhibition of EED ( 1 to 441 residues) (unknown origin) pre-incubated for 15 mins before biotin-H3K27me3 (19 to 33 residues) addition and further inc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetPolycomb protein EED(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50540011(CHEMBL4645310)
Affinity DataIC50: 0.400nMAssay Description:Inhibition of EED ( 1 to 441 residues) (unknown origin) pre-incubated for 15 mins before biotin-H3K27me3 (19 to 33 residues) addition and further inc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetPolycomb protein EED(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50540017(CHEMBL4644746)
Affinity DataIC50: 0.400nMAssay Description:Inhibition of EED ( 1 to 441 residues) (unknown origin) pre-incubated for 15 mins before biotin-H3K27me3 (19 to 33 residues) addition and further inc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetPolycomb protein EED(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50573346(CHEMBL4865691)
Affinity DataIC50: 0.400nMAssay Description:Inhibition of biotinylated H3K27Me3 peptide (19 to 33 residues) binding to His-tagged EED (1 to 441 residues) (unknown origin) preincubated for 15 mi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetPolycomb protein EED(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50540016(CHEMBL4635558)
Affinity DataIC50: 0.5nMAssay Description:Inhibition of EED ( 1 to 441 residues) (unknown origin) pre-incubated for 15 mins before biotin-H3K27me3 (19 to 33 residues) addition and further inc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetPolycomb protein EED(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50540018(CHEMBL4642335)
Affinity DataIC50: 0.5nMAssay Description:Inhibition of EED ( 1 to 441 residues) (unknown origin) pre-incubated for 15 mins before biotin-H3K27me3 (19 to 33 residues) addition and further inc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetPolycomb protein EED(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50573335(CHEMBL4851576)
Affinity DataIC50: 0.5nMAssay Description:Inhibition of biotinylated H3K27Me3 peptide (19 to 33 residues) binding to His-tagged EED (1 to 441 residues) (unknown origin) preincubated for 15 mi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetPolycomb protein EED(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50573339(CHEMBL4872891)
Affinity DataIC50: 0.600nMAssay Description:Inhibition of biotinylated H3K27Me3 peptide (19 to 33 residues) binding to His-tagged EED (1 to 441 residues) (unknown origin) preincubated for 15 mi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetPolycomb protein EED(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50573349(CHEMBL4869420)
Affinity DataIC50: 0.600nMAssay Description:Inhibition of biotinylated H3K27Me3 peptide (19 to 33 residues) binding to His-tagged EED (1 to 441 residues) (unknown origin) preincubated for 15 mi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetPolycomb protein EED(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50573350(CHEMBL4877375)
Affinity DataIC50: 0.600nMAssay Description:Inhibition of biotinylated H3K27Me3 peptide (19 to 33 residues) binding to His-tagged EED (1 to 441 residues) (unknown origin) preincubated for 15 mi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetPolycomb protein EED(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50573363(CHEMBL4860499)
Affinity DataIC50: 0.600nMAssay Description:Inhibition of biotinylated H3K27Me3 peptide (19 to 33 residues) binding to His-tagged EED (1 to 441 residues) (unknown origin) preincubated for 15 mi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetPolycomb protein EED(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50540007(CHEMBL4640949)
Affinity DataIC50: 0.700nMAssay Description:Inhibition of EED ( 1 to 441 residues) (unknown origin) pre-incubated for 15 mins before biotin-H3K27me3 (19 to 33 residues) addition and further inc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetPolycomb protein EED(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50573337(CHEMBL4873268)
Affinity DataIC50: 0.700nMAssay Description:Inhibition of biotinylated H3K27Me3 peptide (19 to 33 residues) binding to His-tagged EED (1 to 441 residues) (unknown origin) preincubated for 15 mi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetPolycomb protein EED(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50573343(CHEMBL4861749)
Affinity DataIC50: 0.700nMAssay Description:Inhibition of biotinylated H3K27Me3 peptide (19 to 33 residues) binding to His-tagged EED (1 to 441 residues) (unknown origin) preincubated for 15 mi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetPolycomb protein EED(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50573345(CHEMBL4859559)
Affinity DataIC50: 0.700nMAssay Description:Inhibition of biotinylated H3K27Me3 peptide (19 to 33 residues) binding to His-tagged EED (1 to 441 residues) (unknown origin) preincubated for 15 mi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetPolycomb protein EED(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50573359(CHEMBL4850823)
Affinity DataIC50: 0.700nMAssay Description:Inhibition of biotinylated H3K27Me3 peptide (19 to 33 residues) binding to His-tagged EED (1 to 441 residues) (unknown origin) preincubated for 15 mi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetPolycomb protein EED(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50540015(CHEMBL4640556)
Affinity DataIC50: 0.800nMAssay Description:Inhibition of EED ( 1 to 441 residues) (unknown origin) pre-incubated for 15 mins before biotin-H3K27me3 (19 to 33 residues) addition and further inc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetPolycomb protein EED(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50573338(CHEMBL4862163)
Affinity DataIC50: 0.800nMAssay Description:Inhibition of biotinylated H3K27Me3 peptide (19 to 33 residues) binding to His-tagged EED (1 to 441 residues) (unknown origin) preincubated for 15 mi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetPolycomb protein EED(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50573353(CHEMBL4856280)
Affinity DataIC50: 0.800nMAssay Description:Inhibition of biotinylated H3K27Me3 peptide (19 to 33 residues) binding to His-tagged EED (1 to 441 residues) (unknown origin) preincubated for 15 mi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetPolycomb protein EED(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50573357(CHEMBL4878932)
Affinity DataIC50: 0.800nMAssay Description:Inhibition of biotinylated H3K27Me3 peptide (19 to 33 residues) binding to His-tagged EED (1 to 441 residues) (unknown origin) preincubated for 15 mi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetPolycomb protein EED(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50540010(CHEMBL4649099)
Affinity DataIC50: 0.900nMAssay Description:Inhibition of EED ( 1 to 441 residues) (unknown origin) pre-incubated for 15 mins before biotin-H3K27me3 (19 to 33 residues) addition and further inc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetPolycomb protein EED(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM291686(US9580437, Example 1 | 8-(1,3-Dimethyl-1H-pyrazol-...)
Affinity DataIC50: 0.900nMAssay Description:Representative compounds of the present disclosure were serially and separately diluted 3-fold in DMSO to obtain a total of eight or twelve concentra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetPolycomb protein EED(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM291695(US9580437, Example 10 | 3-(5-(((5-fluoro-2,3-dihyd...)
Affinity DataIC50: 1nMAssay Description:Representative compounds of the present disclosure were serially and separately diluted 3-fold in DMSO to obtain a total of eight or twelve concentra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetPolycomb protein EED(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50573360(CHEMBL4856160)
Affinity DataIC50: 1nMAssay Description:Inhibition of biotinylated H3K27Me3 peptide (19 to 33 residues) binding to His-tagged EED (1 to 441 residues) (unknown origin) preincubated for 15 mi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetPolycomb protein EED(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50573364(CHEMBL4854206)
Affinity DataIC50: 1nMAssay Description:Inhibition of biotinylated H3K27Me3 peptide (19 to 33 residues) binding to His-tagged EED (1 to 441 residues) (unknown origin) preincubated for 15 mi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetPolycomb protein EED(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50573361(CHEMBL4850847)
Affinity DataIC50: 1.10nMAssay Description:Inhibition of biotinylated H3K27Me3 peptide (19 to 33 residues) binding to His-tagged EED (1 to 441 residues) (unknown origin) preincubated for 15 mi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetPolycomb protein EED(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50573341(CHEMBL4847943)
Affinity DataIC50: 1.20nMAssay Description:Inhibition of biotinylated H3K27Me3 peptide (19 to 33 residues) binding to His-tagged EED (1 to 441 residues) (unknown origin) preincubated for 15 mi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetPolycomb protein EED(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM291815(US9580437, Example 130 | (5-(5-(((5-fluoro-2,3-dih...)
Affinity DataIC50: 1.30nMAssay Description:Representative compounds of the present disclosure were serially and separately diluted 3-fold in DMSO to obtain a total of eight or twelve concentra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetPolycomb protein EED(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM291908(US9580437, Example 223 | 8-(6-((dimethylamino)meth...)
Affinity DataIC50: 1.40nMAssay Description:Representative compounds of the present disclosure were serially and separately diluted 3-fold in DMSO to obtain a total of eight or twelve concentra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetPolycomb protein EED(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM291925(US9580437, Example 240 | N-((5-fluoro-2,3-dihydrob...)
Affinity DataIC50: 1.40nMAssay Description:Representative compounds of the present disclosure were serially and separately diluted 3-fold in DMSO to obtain a total of eight or twelve concentra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetPolycomb protein EED(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50573355(CHEMBL4861394)
Affinity DataIC50: 1.40nMAssay Description:Inhibition of biotinylated H3K27Me3 peptide (19 to 33 residues) binding to His-tagged EED (1 to 441 residues) (unknown origin) preincubated for 15 mi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetPolycomb protein EED(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM291909(US9580437, Example 224 | 8-(6-ethyl-4-methylpyridi...)
Affinity DataIC50: 1.5nMAssay Description:To assess the compounds potency in the EED-H3K27Me3 competition binding assay, compounds were serially diluted 3-fold in DMSO to obtain a total of tw...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetPolycomb protein EED(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50573352(CHEMBL4871261)
Affinity DataIC50: 1.5nMAssay Description:Inhibition of biotinylated H3K27Me3 peptide (19 to 33 residues) binding to His-tagged EED (1 to 441 residues) (unknown origin) preincubated for 15 mi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetPolycomb protein EED(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM291824(US9580437, Example 139 | N-((5-fluoro-2,3-dihydrob...)
Affinity DataIC50: 1.60nMAssay Description:Representative compounds of the present disclosure were serially and separately diluted 3-fold in DMSO to obtain a total of eight or twelve concentra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetPolycomb protein EED(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50573354(CHEMBL4854800)
Affinity DataIC50: 1.60nMAssay Description:Inhibition of biotinylated H3K27Me3 peptide (19 to 33 residues) binding to His-tagged EED (1 to 441 residues) (unknown origin) preincubated for 15 mi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetPolycomb protein EED(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50573358(CHEMBL4849266)
Affinity DataIC50: 1.60nMAssay Description:Inhibition of biotinylated H3K27Me3 peptide (19 to 33 residues) binding to His-tagged EED (1 to 441 residues) (unknown origin) preincubated for 15 mi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetPolycomb protein EED(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50573365(CHEMBL4858089)
Affinity DataIC50: 1.60nMAssay Description:Inhibition of biotinylated H3K27Me3 peptide (19 to 33 residues) binding to His-tagged EED (1 to 441 residues) (unknown origin) preincubated for 15 mi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetPolycomb protein EED(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM291824(US9580437, Example 139 | N-((5-fluoro-2,3-dihydrob...)
Affinity DataIC50: 1.70nMAssay Description:To assess the compounds potency in the EED-H3K27Me3 competition binding assay, compounds were serially diluted 3-fold in DMSO to obtain a total of tw...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetPolycomb protein EED(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM450978(US10676479, Example 10 | 1-Chloro-8-(2,4-dimethylp...)
Affinity DataIC50: 1.80nMAssay Description:Inhibition of EED ( 1 to 441 residues) (unknown origin) pre-incubated for 15 mins before biotin-H3K27me3 (19 to 33 residues) addition and further inc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetPolycomb protein EED(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50573362(CHEMBL4858561)
Affinity DataIC50: 1.80nMAssay Description:Inhibition of biotinylated H3K27Me3 peptide (19 to 33 residues) binding to His-tagged EED (1 to 441 residues) (unknown origin) preincubated for 15 mi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetPolycomb protein EED(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM291814(US9580437, Example 129 | (5-(5-(((5-fluoro-2,3-dih...)
Affinity DataIC50: 1.90nMAssay Description:Representative compounds of the present disclosure were serially and separately diluted 3-fold in DMSO to obtain a total of eight or twelve concentra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetPolycomb protein EED(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM291823(US9580437, Example 138 | 8-(4-chloro-6-methoxypyri...)
Affinity DataIC50: 1.90nMAssay Description:To assess the compounds potency in the EED-H3K27Me3 competition binding assay, compounds were serially diluted 3-fold in DMSO to obtain a total of tw...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetPolycomb protein EED(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM291909(US9580437, Example 224 | 8-(6-ethyl-4-methylpyridi...)
Affinity DataIC50: 1.90nMAssay Description:Representative compounds of the present disclosure were serially and separately diluted 3-fold in DMSO to obtain a total of eight or twelve concentra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetPolycomb protein EED(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM172038(US10647700, Compound EPZ6438 | BDBM190183 | US1015...)
Affinity DataIC50: 2nMAssay Description:Inhibition of recombinant N-terminal GST-tagged EED (76 to 441 residues) (unknown origin) expressed in Escherichia coli BL21-CodonPlus(DE3)-RIL asses...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPolycomb protein EED(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM291853(US9580437, Example 168 | 8-(2-(difluoromethyl)pyri...)
Affinity DataIC50: 2nMAssay Description:Representative compounds of the present disclosure were serially and separately diluted 3-fold in DMSO to obtain a total of eight or twelve concentra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

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