Compile Data Set for Download or QSAR
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TargetLysine-specific demethylase 4A(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50454844(CHEMBL4204694)
Affinity DataIC50: 6nMAssay Description:Inhibition of KDM4A (unknown origin) expressed in Escherichia coli using biotinylated peptide as substrate pretreated for 15 mins followed by substra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetLysine-specific demethylase 4A(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50598661(CHEMBL5203487)
Affinity DataIC50: 6nMAssay Description:Inhibition of KDM4A (unknown origin) measured by AlphaScreen assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetLysine-specific demethylase 4A(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50454854(CHEMBL4209038)
Affinity DataIC50: 11nMAssay Description:Inhibition of KDM4A (unknown origin) expressed in Escherichia coli using biotinylated peptide as substrate pretreated for 15 mins followed by substra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetLysine-specific demethylase 4A(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50513345(CHEMBL4438830)
Affinity DataIC50: 13nMAssay Description:Inhibition of full length human KDM4A A482E mutant assessed as decrease in demethylation of substrate using peptide (ARTKQTARK(Me3)STGGKAPRKQLA-GGKbi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetLysine-specific demethylase 4A(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50454848(CHEMBL4205285)
Affinity DataIC50: 15nMAssay Description:Inhibition of KDM4A (unknown origin) expressed in Escherichia coli using biotinylated peptide as substrate pretreated for 15 mins followed by substra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetLysine-specific demethylase 4A(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50513343(CHEMBL4449500)
Affinity DataIC50: 15nMAssay Description:Inhibition of full length human KDM4A A482E mutant assessed as decrease in demethylation of substrate using peptide (ARTKQTARK(Me3)STGGKAPRKQLA-GGKbi...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLysine-specific demethylase 4A(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50454855(CHEMBL4215000)
Affinity DataIC50: 17nMAssay Description:Inhibition of KDM4A (unknown origin) expressed in Escherichia coli using biotinylated peptide as substrate pretreated for 15 mins followed by substra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetLysine-specific demethylase 4A(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50513345(CHEMBL4438830)
Affinity DataIC50: 17nMAssay Description:Inhibition of full length human KDM4A A482E mutant assessed as decrease in demethylation of substrate using peptide (ARTKQTARK(Me3)STGGKAPRKQLA-GGKbi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetLysine-specific demethylase 4A(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50513343(CHEMBL4449500)
Affinity DataIC50: 22nMAssay Description:Inhibition of full length human KDM4A A482E mutant assessed as decrease in demethylation of substrate using peptide (ARTKQTARK(Me3)STGGKAPRKQLA-GGKbi...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLysine-specific demethylase 4A(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50454849(CHEMBL4218675)
Affinity DataIC50: 23nMAssay Description:Inhibition of KDM4A (unknown origin) expressed in Escherichia coli using biotinylated peptide as substrate pretreated for 15 mins followed by substra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetLysine-specific demethylase 4A(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50513345(CHEMBL4438830)
Affinity DataIC50: 25nMAssay Description:Inhibition of full length human KDM4A A482E mutant assessed as decrease in demethylation of substrate using peptide (ARTKQTARK(Me3)STGGKAPRKQLA-GGKbi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetLysine-specific demethylase 4A(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50513343(CHEMBL4449500)
Affinity DataIC50: 25nMAssay Description:Inhibition of full length human KDM4A A482E mutant assessed as decrease in demethylation of substrate using peptide (ARTKQTARK(Me3)STGGKAPRKQLA-GGKbi...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLysine-specific demethylase 4A(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50454859(CHEMBL4206181)
Affinity DataIC50: 31nMAssay Description:Inhibition of KDM4A (unknown origin) expressed in Escherichia coli using biotinylated peptide as substrate pretreated for 15 mins followed by substra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetLysine-specific demethylase 4A(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50598660(CHEMBL5203308)
Affinity DataIC50: 33nMAssay Description:Inhibition of KDM4A (unknown origin) measured by AlphaScreen assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetLysine-specific demethylase 4A(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50454858(CHEMBL4218774)
Affinity DataIC50: 34nMAssay Description:Inhibition of KDM4A (unknown origin) expressed in Escherichia coli using biotinylated peptide as substrate pretreated for 15 mins followed by substra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetLysine-specific demethylase 4A(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM293660(3-({[(1S)-6-[methyl(phenyl)amino]-1,2,3,4-tetrahyd...)
Affinity DataIC50: 35nMAssay Description:Inhibition of KDM4A (unknown origin) using H3K9me3 as substrate and measured by LANCE TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails
PubMedPDB3D3D Structure (crystal)
TargetLysine-specific demethylase 4A(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50513345(CHEMBL4438830)
Affinity DataIC50: 38nMAssay Description:Inhibition of N-terminal His-tagged recombinant human KDM4A (1 to 359 residues) expressed in Escherichia coli assessed as decrease in demethylation o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetLysine-specific demethylase 4A(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50513345(CHEMBL4438830)
Affinity DataIC50: 39nMAssay Description:Inhibition of full length human KDM4A A482E mutant assessed as decrease in demethylation of substrate using peptide (ARTKQTARK(Me3)STGGKAPRKQLA-GGKbi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetLysine-specific demethylase 4A(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50513343(CHEMBL4449500)
Affinity DataIC50: 39nMAssay Description:Inhibition of full length human KDM4A A482E mutant assessed as decrease in demethylation of substrate using peptide (ARTKQTARK(Me3)STGGKAPRKQLA-GGKbi...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLysine-specific demethylase 4A(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50454846(CHEMBL4211201)
Affinity DataIC50: 41nMAssay Description:Inhibition of KDM4A (unknown origin) expressed in Escherichia coli using biotinylated peptide as substrate pretreated for 15 mins followed by substra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetLysine-specific demethylase 4A(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50454847(CHEMBL4203936)
Affinity DataIC50: 41nMAssay Description:Inhibition of KDM4A (unknown origin) expressed in Escherichia coli using biotinylated peptide as substrate pretreated for 15 mins followed by substra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetLysine-specific demethylase 4A(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50520629(CHEMBL4532618)
Affinity DataIC50: 42nMAssay Description:Inhibition of N-terminal His6-tagged KDM4A (1 to 359 residues) (unknown origin) expressed in Escherichia coli BL21(DE3) preincubated for 15 mins foll...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetLysine-specific demethylase 4A(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50454853(CHEMBL4205183)
Affinity DataIC50: 43nMAssay Description:Inhibition of KDM4A (unknown origin) expressed in Escherichia coli using biotinylated peptide as substrate pretreated for 15 mins followed by substra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetLysine-specific demethylase 4A(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50513361(CHEMBL4567766)
Affinity DataIC50: 56nMAssay Description:Inhibition of N-terminal His-tagged recombinant human KDM4A (1 to 359 residues) expressed in Escherichia coli assessed as decrease in demethylation o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetLysine-specific demethylase 4A(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50513372(CHEMBL4440395)
Affinity DataIC50: 59nMAssay Description:Inhibition of N-terminal His-tagged recombinant human KDM4A (1 to 359 residues) expressed in Escherichia coli assessed as decrease in demethylation o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetLysine-specific demethylase 4A(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50513345(CHEMBL4438830)
Affinity DataIC50: 60nMAssay Description:Inhibition of full length human KDM4A A482E mutant assessed as decrease in demethylation of substrate using peptide (ARTKQTARK(Me3)STGGKAPRKQLA-GGKbi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetLysine-specific demethylase 4A(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50513343(CHEMBL4449500)
Affinity DataIC50: 61nMAssay Description:Inhibition of full length human KDM4A A482E mutant assessed as decrease in demethylation of substrate using peptide (ARTKQTARK(Me3)STGGKAPRKQLA-GGKbi...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLysine-specific demethylase 4A(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50513371(CHEMBL4438034)
Affinity DataIC50: 68nMAssay Description:Inhibition of N-terminal His-tagged recombinant human KDM4A (1 to 359 residues) expressed in Escherichia coli assessed as decrease in demethylation o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetLysine-specific demethylase 4A(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50513351(CHEMBL4516101)
Affinity DataIC50: 71nMAssay Description:Inhibition of N-terminal His-tagged recombinant human KDM4A (1 to 359 residues) expressed in Escherichia coli assessed as decrease in demethylation o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetLysine-specific demethylase 4A(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50513374(CHEMBL4466130)
Affinity DataIC50: 77nMAssay Description:Inhibition of N-terminal His-tagged recombinant human KDM4A (1 to 359 residues) expressed in Escherichia coli assessed as decrease in demethylation o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetLysine-specific demethylase 4A(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50153092(CHEMBL3775894)
Affinity DataIC50: 80nMAssay Description:Inhibition of human N-terminal His-tagged KDM4A (1 to 359 residues) expressed in Escherichia coli using biotin-H3K9me3 as substrate preincubated for ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetLysine-specific demethylase 4A(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50454845(CHEMBL4213743)
Affinity DataIC50: 81nMAssay Description:Inhibition of KDM4A (unknown origin) expressed in Escherichia coli using biotinylated peptide as substrate pretreated for 15 mins followed by substra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetLysine-specific demethylase 4A(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50454857(CHEMBL4218482)
Affinity DataIC50: 82nMAssay Description:Inhibition of KDM4A (unknown origin) expressed in Escherichia coli using biotinylated peptide as substrate pretreated for 15 mins followed by substra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetLysine-specific demethylase 4A(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50513352(CHEMBL4592908)
Affinity DataIC50: 83nMAssay Description:Inhibition of N-terminal His-tagged recombinant human KDM4A (1 to 359 residues) expressed in Escherichia coli assessed as decrease in demethylation o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetLysine-specific demethylase 4A(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50513344(CHEMBL4447515)
Affinity DataIC50: 84nMAssay Description:Inhibition of N-terminal His-tagged recombinant human KDM4A (1 to 359 residues) expressed in Escherichia coli assessed as decrease in demethylation o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetLysine-specific demethylase 4A(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50513354(CHEMBL4558689)
Affinity DataIC50: 88nMAssay Description:Inhibition of N-terminal His-tagged recombinant human KDM4A (1 to 359 residues) expressed in Escherichia coli assessed as decrease in demethylation o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetLysine-specific demethylase 4A(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50513348(CHEMBL4585876)
Affinity DataIC50: 93nMAssay Description:Inhibition of N-terminal His-tagged recombinant human KDM4A (1 to 359 residues) expressed in Escherichia coli assessed as decrease in demethylation o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetLysine-specific demethylase 4A(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM191600(US9714230, 89 | 2-(5-((4-chloro-2-methylbenzyl)oxy...)
Affinity DataIC50: 99nMAssay Description:Inhibition of KDM4A (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLysine-specific demethylase 4A(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50153318(CHEMBL3775237)
Affinity DataIC50: 100nMAssay Description:Inhibition of KDM4A (unknown origin) using H3K9Me3 peptide as substrate assessed as demethylation of substrate by Rapidfire mass spectrometric analys...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLysine-specific demethylase 4A(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50153319(CHEMBL3775889)
Affinity DataIC50: 100nMAssay Description:Inhibition of KDM4A (unknown origin) using H3K9Me3 peptide as substrate assessed as demethylation of substrate by Rapidfire mass spectrometric analys...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLysine-specific demethylase 4A(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50158693(CHEMBL3787133 | US10273222, Example 1)
Affinity DataIC50: 100nMAssay Description:Inhibition of recombinant human N-terminal His-tagged KDM4A (1 to 350 residues) expressed in Escherichia coli using biotin-H3K9me3 substrate incubate...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLysine-specific demethylase 4A(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50158806(CHEMBL3786108)
Affinity DataIC50: 100nMAssay Description:Inhibition of recombinant human N-terminal His-tagged KDM4A (1 to 350 residues) expressed in Escherichia coli using biotin-H3K9me3 substrate incubate...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLysine-specific demethylase 4A(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50158621(CHEMBL3785421)
Affinity DataIC50: 100nMAssay Description:Inhibition of recombinant human N-terminal His-tagged KDM4A (1 to 350 residues) expressed in Escherichia coli using biotin-H3K9me3 substrate incubate...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLysine-specific demethylase 4A(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM191598(KDOAM-20 | KDM5-C49 | 2-(((2-((2-(dimethylamino)et...)
Affinity DataIC50: 100nMAssay Description:Inhibition of recombinant human N-terminal His-tagged KDM4A (1 to 350 residues) expressed in Escherichia coli using methylated biotin-H3K9 substrate ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLysine-specific demethylase 4A(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM320363(US10174026, Example 3 | 2-(2-methylphenyl)-1H- pyr...)
Affinity DataIC50: 100nMAssay Description:The ability of test compounds to inhibit the activity of JMJD2A was determined in 384-well plate format under the following reaction conditions: 2 nM...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetLysine-specific demethylase 4A(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM320432(US10174026, Example 99 | 2-(pyrrolidin-1-ylcarbony...)
Affinity DataIC50: 100nMAssay Description:The ability of test compounds to inhibit the activity of JMJD2A was determined in 384-well plate format under the following reaction conditions: 2 nM...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetLysine-specific demethylase 4A(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM320446(US10174026, Example 126 | 2-(3,4-difluorobenzyl)-1...)
Affinity DataIC50: 100nMAssay Description:The ability of test compounds to inhibit the activity of JMJD2A was determined in 384-well plate format under the following reaction conditions: 2 nM...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetLysine-specific demethylase 4A(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM263974(2-(5-(benzyloxy)-1H-pyrazol-1- yl)isonicotinic aci...)
Affinity DataIC50: 100nMAssay Description:The ability of test compounds to inhibit the activity of JMJD2A was determined in 38-well plate format under the following reaction conditions: 2 nM ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetLysine-specific demethylase 4A(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50158693(CHEMBL3787133 | US10273222, Example 1)
Affinity DataIC50: 100nMAssay Description:The ability of test compounds to inhibit the activity of JMJD2A was determined in 384-well plate format under the following reaction conditions: 2 nM...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetLysine-specific demethylase 4A(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM381980(2-[1-[2-[(4-fluorophenyl)methyl- methylamino]ethyl...)
Affinity DataIC50: 100nMAssay Description:The ability of test compounds to inhibit the activity of JMJD2A was determined in 384-well plate format under the following reaction conditions: 2 nM...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

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