Compile Data Set for Download or QSAR
Report error Found 32 of ic50 data for polymerid = 8392,11212
TargetSerine/threonine-protein phosphatase 2A activator(Human)
The University of Tokyo

LigandPNGBDBM40777(Hemicalyculin A (5))
Affinity DataIC50: 1nMAssay Description:Protein phosphatase inhibitory activity of calyculin derivatives.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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PubMed
TargetSerine/threonine-protein phosphatase 2A activator(Human)
The University of Tokyo

LigandPNGBDBM40776(Calyculin F (23) | Calyculin E (22) | Calyculin B ...)
Affinity DataIC50: 1nMAssay Description:Protein phosphatase inhibitory activity of calyculin derivatives.More data for this Ligand-Target Pair
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PubMed
TargetSerine/threonine-protein phosphatase 2A activator(Human)
The University of Tokyo

LigandPNGBDBM40787(Des-N-methylcalyculin A (20))
Affinity DataIC50: 1nMAssay Description:Protein phosphatase inhibitory activity of calyculin derivatives.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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PubMed
TargetSerine/threonine-protein phosphatase 2A activator(Human)
The University of Tokyo

LigandPNGBDBM40782(C1/C34-Calyculin A (15))
Affinity DataIC50: 1.10nMAssay Description:Protein phosphatase inhibitory activity of calyculin derivatives.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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PubMed
TargetSerine/threonine-protein phosphatase 2A activator(Human)
The University of Tokyo

LigandPNGBDBM40785(Calyculinamide A (18))
Affinity DataIC50: 1.5nMAssay Description:Protein phosphatase inhibitory activity of calyculin derivatives.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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PubMed
TargetSerine/threonine-protein phosphatase 2A activator(Human)
The University of Tokyo

LigandPNGBDBM40780(Calyculin A 21-acetate (13))
Affinity DataIC50: 2.10nMAssay Description:Protein phosphatase inhibitory activity of calyculin derivatives.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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PubMed
TargetSerine/threonine-protein phosphatase 2A activator(Human)
The University of Tokyo

LigandPNGBDBM40790(Calyculin C (24))
Affinity DataIC50: 2.60nMAssay Description:Protein phosphatase inhibitory activity of calyculin derivatives.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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PubMed
TargetSerine/threonine-protein phosphatase 2A activator(Human)
The University of Tokyo

LigandPNGBDBM40776(Calyculin F (23) | Calyculin E (22) | Calyculin B ...)
Affinity DataIC50: 7.5nMAssay Description:Protein phosphatase inhibitory activity of calyculin derivatives.More data for this Ligand-Target Pair
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PubMed
TargetSerine/threonine-protein phosphatase 2A activator(Human)
The University of Tokyo

LigandPNGBDBM40776(Calyculin F (23) | Calyculin E (22) | Calyculin B ...)
Affinity DataIC50: 9nMAssay Description:Protein phosphatase inhibitory activity of calyculin derivatives.More data for this Ligand-Target Pair
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PubMed
TargetSerine/threonine-protein phosphatase 2A activator(Human)
The University of Tokyo

LigandPNGBDBM40776(Calyculin F (23) | Calyculin E (22) | Calyculin B ...)
Affinity DataIC50: 14nMAssay Description:Protein phosphatase inhibitory activity of calyculin derivatives.More data for this Ligand-Target Pair
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PubMed
TargetSerine/threonine-protein phosphatase 2A activator(Human)
The University of Tokyo

LigandPNGBDBM40781(Calyculin J (14))
Affinity DataIC50: 20nMAssay Description:Protein phosphatase inhibitory activity of calyculin derivatives.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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PubMed
TargetSerine/threonine-protein phosphatase 2A activator(Human)
The University of Tokyo

LigandPNGBDBM50127377(10-[3,9-dimethyl-8-(3-methyl-4-oxopentyl)-(9R)-1,7...)
Affinity DataIC50: 500nMAssay Description:Inhibition of protein phosphatase 2A (PP2A) was determined by standard phosphorylase a inhibition assayMore data for this Ligand-Target Pair
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PubMed
TargetSerine/threonine-protein phosphatase 2A activator(Mouse)
Indiana University Research and Technology

US Patent
LigandPNGBDBM50054344(US9522881, 11a-1 L97M74 | CHEMBL3319356 | US984453...)
Affinity DataIC50: 1.09E+3nMAssay Description:For selectivity studies, the PTPs, including LYP, mPTPA, SHP1-D1C, PTP1B, LMPTP, VHR, Laforin and PTPα-D1D2 were expressed and purified from E. ...More data for this Ligand-Target Pair
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US Patent

TargetSerine/threonine-protein phosphatase 2A activator(Human)
The University of Tokyo

LigandPNGBDBM50127375((E)-(R)-4-Hydroxy-2-methyl-hex-2-enedioic acid 6-{...)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of protein phosphatase 2A (PP2A) was determined by standard phosphorylase a inhibition assayMore data for this Ligand-Target Pair
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PubMed
TargetSerine/threonine-protein phosphatase 2A activator(Human)
The University of Tokyo

LigandPNGBDBM50366883(TAUTOMYCIN)
Affinity DataIC50: 9.40E+3nMAssay Description:Inhibition of protein phosphatase 2A (PP2A) was determined by standard phosphorylase a inhibition assayMore data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
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PubMed
TargetSerine/threonine-protein phosphatase 2A activator(Human)
The University of Tokyo

LigandPNGBDBM50222937(CHEMBL23732)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory activity against protein phosphatase (PP2A) using fluorescein diphosphate as substrateMore data for this Ligand-Target Pair
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PubMed
TargetSerine/threonine-protein phosphatase 2A activator(Human)
The University of Tokyo

LigandPNGBDBM50222936(CHEMBL18962)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory activity against protein phosphatase (PP2A) using fluorescein diphosphate as substrateMore data for this Ligand-Target Pair
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PubMed
TargetSerine/threonine-protein phosphatase 2A activator(Human)
The University of Tokyo

LigandPNGBDBM40784(Dephosphonocalyculin A (17))
Affinity DataIC50: 1.00E+4nMAssay Description:Protein phosphatase inhibitory activity of calyculin derivatives.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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PubMed
TargetSerine/threonine-protein phosphatase 2A activator(Human)
The University of Tokyo

LigandPNGBDBM40783(C9/C35-calyculin (16))
Affinity DataIC50: 1.00E+4nMAssay Description:Protein phosphatase inhibitory activity of calyculin derivatives.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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PubMed
TargetSerine/threonine-protein phosphatase 2A activator(Human)
The University of Tokyo

LigandPNGBDBM40779(Calyculin A 11,13,21-triacetate (12))
Affinity DataIC50: 1.00E+4nMAssay Description:Protein phosphatase inhibitory activity of calyculin derivatives.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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PubMed
TargetSerine/threonine-protein phosphatase 2A activator(Human)
The University of Tokyo

LigandPNGBDBM40778(11,13-O-isopropylidene-calyculin A (6))
Affinity DataIC50: 1.00E+4nMAssay Description:Protein phosphatase inhibitory activity of calyculin derivatives.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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PubMed
TargetSerine/threonine-protein phosphatase 2A activator(Human)
The University of Tokyo

LigandPNGBDBM50307997(2-(2-Carboxy-benzoylamino)-4-(30-chloro-40-fluorob...)
Affinity DataIC50: 2.31E+4nMAssay Description:Inhibition of PTPalpha expressed in Escherichia coli BL21 (DE3) after 10 mins by spectrophotometryMore data for this Ligand-Target Pair
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PubMed
TargetSerine/threonine-protein phosphatase 2A activator(Human)
The University of Tokyo

LigandPNGBDBM50127378((S)-2-Hydroxy-2-methyl-succinic acid 4-{(1R,2S,3R,...)
Affinity DataIC50: 2.90E+4nMAssay Description:Inhibition of protein phosphatase 2A (PP2A) was determined by standard phosphorylase a inhibition assayMore data for this Ligand-Target Pair
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PubMed
TargetSerine/threonine-protein phosphatase 2A activator(Human)
The University of Tokyo

LigandPNGBDBM50544431(CHEMBL4637459 | US11192850, Entry 4k)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of PTPA (unknown origin) expressed in Escherichia coli BL21 using p-nitrophenyl phosphate as substrate measured after 30 mins by UV-vis sp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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PubMed
TargetSerine/threonine-protein phosphatase 2A activator(Human)
The University of Tokyo

LigandPNGBDBM50544440(CHEMBL4647367 | US11192850, Entry 4t)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of PTPA (unknown origin) expressed in Escherichia coli BL21 using p-nitrophenyl phosphate as substrate measured after 30 mins by UV-vis sp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetSerine/threonine-protein phosphatase 2A activator(Human)
The University of Tokyo

LigandPNGBDBM50307999(4-Biphenyl-4-yl-2-(2-carboxy-benzoylamino)-5-methy...)
Affinity DataIC50: 4.97E+4nMAssay Description:Inhibition of PTPalpha expressed in Escherichia coli BL21 (DE3) after 10 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine/threonine-protein phosphatase 2A activator(Human)
The University of Tokyo

LigandPNGBDBM50544427(CHEMBL4632818 | US11192850, Entry 4g)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of PTPA (unknown origin) expressed in Escherichia coli BL21 using p-nitrophenyl phosphate as substrate measured after 30 mins by UV-vis sp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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PubMed
TargetSerine/threonine-protein phosphatase 2A activator(Human)
The University of Tokyo

LigandPNGBDBM50307989(4-Biphenyl-4-yl-2-[(3-carboxy-bicyclo[2.2.1]hept-5...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of PTPalpha expressed in Escherichia coli BL21 (DE3) after 10 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine/threonine-protein phosphatase 2A activator(Human)
The University of Tokyo

LigandPNGBDBM50307990(2-[(3-Carboxy-bicyclo[2.2.1]hept-5-ene-2-carbonyl)...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of PTPalpha expressed in Escherichia coli BL21 (DE3) after 10 mins by spectrophotometryMore data for this Ligand-Target Pair
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PubMed
TargetSerine/threonine-protein phosphatase 2A activator(Human)
The University of Tokyo

LigandPNGBDBM50308000(3-(3,5-dibromo-4-hydroxybenzoyl)-2-ethyl-N-(thiazo...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of PTPalpha expressed in Escherichia coli BL21 (DE3) after 10 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine/threonine-protein phosphatase 2A activator(Human)
The University of Tokyo

LigandPNGBDBM50127376((R)-2-Hydroxy-2-methyl-succinic acid 4-{(1R,2S,3R,...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of protein phosphatase 2A (PP2A) was determined by standard phosphorylase a inhibition assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine/threonine-protein phosphatase 2A activator(Human)
The University of Tokyo

LigandPNGBDBM50127379(4-Phosphono-butyric acid (1R,2S,3R,6S,7S,10R)-10-[...)
Affinity DataIC50: 3.00E+5nMAssay Description:Inhibition of protein phosphatase 2A (PP2A) was determined by standard phosphorylase a inhibition assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed