Compile Data Set for Download or QSAR
Report error Found 384 of ic50 data for polymerid = 8286,49000763
TargetMetabotropic glutamate receptor 7(Rat)
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50305863(3-(3-methoxyphenyl)-5-methyl-6-phenylisoxazolo[4,5...)
Affinity DataIC50: 12nMAssay Description:Antagonist activity at rat mGluR7 expressed in CHO cells assessed as inhibition of LAP-induced intracellular calcium mobilization by FLIPRMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMetabotropic glutamate receptor 7(Rat)
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50305859(CHEMBL595840 | cid_4250909 | 5-methyl-3,6-diphenyl...)
Affinity DataIC50: 20nMAssay Description:Antagonist activity at rat mGluR7 expressed in CHO cells assessed as inhibition of LAP-induced intracellular calcium mobilization by FLIPRMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMetabotropic glutamate receptor 7(Rat)
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50305864(3-(2-methoxyphenyl)-5-methyl-6-phenylisoxazolo[4,5...)
Affinity DataIC50: 21nMAssay Description:Antagonist activity at rat mGluR7 expressed in CHO cells assessed as inhibition of LAP-induced intracellular calcium mobilization by FLIPRMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMetabotropic glutamate receptor 7(Rat)
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50196289(6-(4-methoxyphenyl)-5-methyl-3-phenylisoxazolo[4,5...)
Affinity DataIC50: 22nMAssay Description:Antagonist activity at rat mGluR7 expressed in CHO cells assessed as inhibition of LAP-induced intracellular calcium mobilization by FLIPRMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMetabotropic glutamate receptor 7(Rat)
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50196291(6-(benzo[d][1,3]dioxol-5-yl)-5-methyl-3-phenylisox...)
Affinity DataIC50: 26nMAssay Description:Antagonist activity at rat mGluR7 expressed in CHO cells assessed as inhibition of LAP-induced intracellular calcium mobilization by FLIPRMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMetabotropic glutamate receptor 7(Rat)
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50305877(6-(4-methoxyphenyl)-5-methyl-3-(pyridin-4-yl)isoxa...)
Affinity DataIC50: 26nMAssay Description:Antagonist activity at rat mGluR7 expressed in CHO cells assessed as inhibition of LAP-induced intracellular calcium mobilization by FLIPRMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMetabotropic glutamate receptor 7(Rat)
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50305862(3-(4-methoxyphenyl)-5-methyl-6-phenylisoxazolo[4,5...)
Affinity DataIC50: 29nMAssay Description:Antagonist activity at rat mGluR7 expressed in CHO cells assessed as inhibition of LAP-induced intracellular calcium mobilization by FLIPRMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMetabotropic glutamate receptor 7(Rat)
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50305873(6-(3-(dimethylamino)phenyl)-5-methyl-3-phenylisoxa...)
Affinity DataIC50: 31nMAssay Description:Antagonist activity at rat mGluR7 expressed in CHO cells assessed as inhibition of LAP-induced intracellular calcium mobilization by FLIPRMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMetabotropic glutamate receptor 7(Rat)
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50305868(5-methyl-3-phenyl-6-p-tolylisoxazolo[4,5-c]pyridin...)
Affinity DataIC50: 51nMAssay Description:Antagonist activity at rat mGluR7 expressed in CHO cells assessed as inhibition of LAP-induced intracellular calcium mobilization by FLIPRMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMetabotropic glutamate receptor 7(Rat)
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50305869(6-(4-fluorophenyl)-5-methyl-3-phenylisoxazolo[4,5-...)
Affinity DataIC50: 72nMAssay Description:Antagonist activity at rat mGluR7 expressed in CHO cells assessed as inhibition of LAP-induced intracellular calcium mobilization by FLIPRMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMetabotropic glutamate receptor 7(Rat)
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50305874(5-methyl-3-phenyl-6-(3-(trifluoromethyl)phenyl)iso...)
Affinity DataIC50: 96nMAssay Description:Antagonist activity at rat mGluR7 expressed in CHO cells assessed as inhibition of LAP-induced intracellular calcium mobilization by FLIPRMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMetabotropic glutamate receptor 7(Rat)
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50305865(5-methyl-6-phenyl-3-(pyridin-4-yl)isoxazolo[4,5-c]...)
Affinity DataIC50: 101nMAssay Description:Antagonist activity at rat mGluR7 expressed in CHO cells assessed as inhibition of LAP-induced intracellular calcium mobilization by FLIPRMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMetabotropic glutamate receptor 7(Rat)
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50305870(6-(4-(dimethylamino)phenyl)-5-methyl-3-phenylisoxa...)
Affinity DataIC50: 140nMAssay Description:Antagonist activity at rat mGluR7 expressed in CHO cells assessed as inhibition of LAP-induced intracellular calcium mobilization by FLIPRMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMetabotropic glutamate receptor 7(Rat)
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50305872(5-methyl-3-phenyl-6-(4-propylphenyl)isoxazolo[4,5-...)
Affinity DataIC50: 150nMAssay Description:Antagonist activity at rat mGluR7 expressed in CHO cells assessed as inhibition of LAP-induced intracellular calcium mobilization by FLIPRMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMetabotropic glutamate receptor 7(Rat)
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50305875(6-(3-fluoro-4-methoxyphenyl)-5-methyl-3-phenylisox...)
Affinity DataIC50: 210nMAssay Description:Antagonist activity at rat mGluR7 expressed in CHO cells assessed as inhibition of LAP-induced intracellular calcium mobilization by FLIPRMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMetabotropic glutamate receptor 7(Rat)
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50305866(5-methyl-6-phenyl-3-(pyridin-3-yl)isoxazolo[4,5-c]...)
Affinity DataIC50: 240nMAssay Description:Antagonist activity at rat mGluR7 expressed in CHO cells assessed as inhibition of LAP-induced intracellular calcium mobilization by FLIPRMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMetabotropic glutamate receptor 7(Rat)
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50589650(CHEMBL5202961)
Affinity DataIC50: 263nMAssay Description:Negative allosteric modulation of rat mGlu7 in HEK cells expressing Galpha15 assessed as inhibition of L-AP4-induced response measured by calcium mob...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetMetabotropic glutamate receptor 7(Rat)
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50589650(CHEMBL5202961)
Affinity DataIC50: 263nMAssay Description:Negative allosteric modulation of rat mGlu7 in HEK cells expressing Galpha15 assessed as inhibition of L-AP4-induced response measured by calcium mob...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetMetabotropic glutamate receptor 7(Rat)
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50531687(CHEMBL4445682)
Affinity DataIC50: 347nMAssay Description:Negative allosteric modulation of rat mGlu7 receptor expressed in HEK cells harboring Ga15 assessed as reduction in L-AP4-induced calcium flux preinc...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMetabotropic glutamate receptor 7(Rat)
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50531687(CHEMBL4445682)
Affinity DataIC50: 347nMAssay Description:Negative allosteric modulation of rat mGlu7 in HEK cells expressing Galpha15 assessed as inhibition of L-AP4-induced response measured by calcium mob...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetMetabotropic glutamate receptor 7(Rat)
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50531687(CHEMBL4445682)
Affinity DataIC50: 350nMAssay Description:Negative allosteric modulation of rat mGlu7 receptor expressed in HEK cells harboring Ga15 assessed as reduction in L-AP4-induced calcium flux preinc...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMetabotropic glutamate receptor 7(Rat)
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50553636(CHEMBL4750685)
Affinity DataIC50: 350nMAssay Description:Negative allosteric modulation of rat mGlu7 receptor expressed in HEK cells co-expressing Galpha15 assessed as reduction in calcium mobilization incu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetMetabotropic glutamate receptor 7(Rat)
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50553631(CHEMBL4739931)
Affinity DataIC50: 370nMAssay Description:Negative allosteric modulation of rat mGlu7 receptor expressed in HEK cells co-expressing Galpha15 assessed as reduction in calcium mobilization incu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetMetabotropic glutamate receptor 7(Rat)
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50553632(CHEMBL4745605)
Affinity DataIC50: 410nMAssay Description:Negative allosteric modulation of rat mGlu7 receptor expressed in HEK cells co-expressing Galpha15 assessed as reduction in calcium mobilization incu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetMetabotropic glutamate receptor 7(Human)
Pragma Therapeutics

US Patent
LigandPNGBDBM565060(US11414395, Example 109)
Affinity DataIC50: 500nMAssay Description:The HTRF-based assays from CisBio Bioassays allow the measure of different cell signaling pathways, notably those allowing the determination of the p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetMetabotropic glutamate receptor 7(Human)
Pragma Therapeutics

US Patent
LigandPNGBDBM565061(US11414395, Example 110)
Affinity DataIC50: 500nMAssay Description:The HTRF-based assays from CisBio Bioassays allow the measure of different cell signaling pathways, notably those allowing the determination of the p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetMetabotropic glutamate receptor 7(Human)
Pragma Therapeutics

US Patent
LigandPNGBDBM565063(US11414395, Example 112)
Affinity DataIC50: 500nMAssay Description:The HTRF-based assays from CisBio Bioassays allow the measure of different cell signaling pathways, notably those allowing the determination of the p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetMetabotropic glutamate receptor 7(Human)
Pragma Therapeutics

US Patent
LigandPNGBDBM565064(US11414395, Example 113)
Affinity DataIC50: 500nMAssay Description:The HTRF-based assays from CisBio Bioassays allow the measure of different cell signaling pathways, notably those allowing the determination of the p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetMetabotropic glutamate receptor 7(Human)
Pragma Therapeutics

US Patent
LigandPNGBDBM565065(US11414395, Example 114)
Affinity DataIC50: 500nMAssay Description:The HTRF-based assays from CisBio Bioassays allow the measure of different cell signaling pathways, notably those allowing the determination of the p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetMetabotropic glutamate receptor 7(Human)
Pragma Therapeutics

US Patent
LigandPNGBDBM565066(US11414395, Example 115)
Affinity DataIC50: 500nMAssay Description:The HTRF-based assays from CisBio Bioassays allow the measure of different cell signaling pathways, notably those allowing the determination of the p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetMetabotropic glutamate receptor 7(Human)
Pragma Therapeutics

US Patent
LigandPNGBDBM565067(US11414395, Example 116)
Affinity DataIC50: 500nMAssay Description:The HTRF-based assays from CisBio Bioassays allow the measure of different cell signaling pathways, notably those allowing the determination of the p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetMetabotropic glutamate receptor 7(Human)
Pragma Therapeutics

US Patent
LigandPNGBDBM565068(US11414395, Example 117)
Affinity DataIC50: 500nMAssay Description:The HTRF-based assays from CisBio Bioassays allow the measure of different cell signaling pathways, notably those allowing the determination of the p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetMetabotropic glutamate receptor 7(Human)
Pragma Therapeutics

US Patent
LigandPNGBDBM565069(US11414395, Example 118)
Affinity DataIC50: 500nMAssay Description:The HTRF-based assays from CisBio Bioassays allow the measure of different cell signaling pathways, notably those allowing the determination of the p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetMetabotropic glutamate receptor 7(Human)
Pragma Therapeutics

US Patent
LigandPNGBDBM565070(US11414395, Example 119)
Affinity DataIC50: 500nMAssay Description:The HTRF-based assays from CisBio Bioassays allow the measure of different cell signaling pathways, notably those allowing the determination of the p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetMetabotropic glutamate receptor 7(Human)
Pragma Therapeutics

US Patent
LigandPNGBDBM565073(US11414395, Example 122)
Affinity DataIC50: 500nMAssay Description:The HTRF-based assays from CisBio Bioassays allow the measure of different cell signaling pathways, notably those allowing the determination of the p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetMetabotropic glutamate receptor 7(Human)
Pragma Therapeutics

US Patent
LigandPNGBDBM565074(US11414395, Example 124)
Affinity DataIC50: 500nMAssay Description:The HTRF-based assays from CisBio Bioassays allow the measure of different cell signaling pathways, notably those allowing the determination of the p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetMetabotropic glutamate receptor 7(Human)
Pragma Therapeutics

US Patent
LigandPNGBDBM565075(US11414395, Example 125)
Affinity DataIC50: 500nMAssay Description:The HTRF-based assays from CisBio Bioassays allow the measure of different cell signaling pathways, notably those allowing the determination of the p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetMetabotropic glutamate receptor 7(Human)
Pragma Therapeutics

US Patent
LigandPNGBDBM565076(US11414395, Example 126)
Affinity DataIC50: 500nMAssay Description:The HTRF-based assays from CisBio Bioassays allow the measure of different cell signaling pathways, notably those allowing the determination of the p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetMetabotropic glutamate receptor 7(Human)
Pragma Therapeutics

US Patent
LigandPNGBDBM565077(US11414395, Example 127)
Affinity DataIC50: 500nMAssay Description:The HTRF-based assays from CisBio Bioassays allow the measure of different cell signaling pathways, notably those allowing the determination of the p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetMetabotropic glutamate receptor 7(Human)
Pragma Therapeutics

US Patent
LigandPNGBDBM565078(US11414395, Example 128)
Affinity DataIC50: 500nMAssay Description:The HTRF-based assays from CisBio Bioassays allow the measure of different cell signaling pathways, notably those allowing the determination of the p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetMetabotropic glutamate receptor 7(Human)
Pragma Therapeutics

US Patent
LigandPNGBDBM565080(US11414395, Example 130)
Affinity DataIC50: 500nMAssay Description:The HTRF-based assays from CisBio Bioassays allow the measure of different cell signaling pathways, notably those allowing the determination of the p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetMetabotropic glutamate receptor 7(Human)
Pragma Therapeutics

US Patent
LigandPNGBDBM565081(US11414395, Example 131)
Affinity DataIC50: 500nMAssay Description:The HTRF-based assays from CisBio Bioassays allow the measure of different cell signaling pathways, notably those allowing the determination of the p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetMetabotropic glutamate receptor 7(Human)
Pragma Therapeutics

US Patent
LigandPNGBDBM565082(US11414395, Example 132)
Affinity DataIC50: 500nMAssay Description:The HTRF-based assays from CisBio Bioassays allow the measure of different cell signaling pathways, notably those allowing the determination of the p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetMetabotropic glutamate receptor 7(Human)
Pragma Therapeutics

US Patent
LigandPNGBDBM565084(US11414395, Example 134)
Affinity DataIC50: 500nMAssay Description:The HTRF-based assays from CisBio Bioassays allow the measure of different cell signaling pathways, notably those allowing the determination of the p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetMetabotropic glutamate receptor 7(Human)
Pragma Therapeutics

US Patent
LigandPNGBDBM565087(US11414395, Example 137)
Affinity DataIC50: 500nMAssay Description:The HTRF-based assays from CisBio Bioassays allow the measure of different cell signaling pathways, notably those allowing the determination of the p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetMetabotropic glutamate receptor 7(Human)
Pragma Therapeutics

US Patent
LigandPNGBDBM565089(US11414395, Example 139)
Affinity DataIC50: 500nMAssay Description:The HTRF-based assays from CisBio Bioassays allow the measure of different cell signaling pathways, notably those allowing the determination of the p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetMetabotropic glutamate receptor 7(Human)
Pragma Therapeutics

US Patent
LigandPNGBDBM564954(US11414395, Example 1)
Affinity DataIC50: 500nMAssay Description:The HTRF-based assays from CisBio Bioassays allow the measure of different cell signaling pathways, notably those allowing the determination of the p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetMetabotropic glutamate receptor 7(Human)
Pragma Therapeutics

US Patent
LigandPNGBDBM564958(US11414395, Example 5)
Affinity DataIC50: 500nMAssay Description:The HTRF-based assays from CisBio Bioassays allow the measure of different cell signaling pathways, notably those allowing the determination of the p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetMetabotropic glutamate receptor 7(Human)
Pragma Therapeutics

US Patent
LigandPNGBDBM564959(US11414395, Example 6)
Affinity DataIC50: 500nMAssay Description:The HTRF-based assays from CisBio Bioassays allow the measure of different cell signaling pathways, notably those allowing the determination of the p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetMetabotropic glutamate receptor 7(Human)
Pragma Therapeutics

US Patent
LigandPNGBDBM564960(US11414395, Example 7)
Affinity DataIC50: 500nMAssay Description:The HTRF-based assays from CisBio Bioassays allow the measure of different cell signaling pathways, notably those allowing the determination of the p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

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