Compile Data Set for Download or QSAR
Report error Found 1884 of ic50 data for polymerid = 8238
TargetLysine-specific demethylase 4C(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50454844(CHEMBL4204694)
Affinity DataIC50: 2.20nMAssay Description:Inhibition of KDM4C (unknown origin) expressed in Escherichia coli using biotinylated peptide as substrate pretreated for 15 mins followed by substra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetLysine-specific demethylase 4C(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50598661(CHEMBL5203487)
Affinity DataIC50: 2.20nMAssay Description:Inhibition of KDM4C (unknown origin) measured by AlphaScreen assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetLysine-specific demethylase 4C(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM263974(2-(5-(benzyloxy)-1H-pyrazol-1- yl)isonicotinic aci...)
Affinity DataIC50: 5nMAssay Description:Inhibition of KDM4C (unknown origin) preincubated with enzymeMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetLysine-specific demethylase 4C(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM321348(US10179769, Example 62 | 3-({[(1R)-6-methoxy-1,2,3...)
Affinity DataIC50: 6nMAssay Description:Inhibition of KDM4C (unknown origin) using biotinylated H3K9me3 peptide and alpha-ketoglutarate as substrate pretreated for 1 hr followed by substrat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails Article
PubMed
TargetLysine-specific demethylase 4C(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM321334(US10179769, Example 48 | 3-{[(1R)-1,2,3,4-tetrahyd...)
Affinity DataIC50: 8nMAssay Description:Inhibition of KDM4C (unknown origin) using biotinylated H3K9me3 peptide and alpha-ketoglutarate as substrate pretreated for 1 hr followed by substrat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetLysine-specific demethylase 4C(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM188286(US9073941, 605)
Affinity DataIC50: 8nMAssay Description:Inhibition of KDM4C (unknown origin) using methylated H3 peptide as substrate by chemiluminescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLysine-specific demethylase 4C(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM293660(3-({[(1S)-6-[methyl(phenyl)amino]-1,2,3,4-tetrahyd...)
Affinity DataIC50: 9nMAssay Description:Inhibition of KDM4C (unknown origin) using biotinylated H3K9me3 peptide and alpha-ketoglutarate as substrate pretreated for 1 hr followed by substrat...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLysine-specific demethylase 4C(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50538952(CHEMBL4648732)
Affinity DataIC50: 11nMAssay Description:Inhibition of KDM4C (unknown origin) using methylated H3 peptide as substrate by chemiluminescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetLysine-specific demethylase 4C(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50454854(CHEMBL4209038)
Affinity DataIC50: 12nMAssay Description:Inhibition of KDM4C (unknown origin) expressed in Escherichia coli using biotinylated peptide as substrate pretreated for 15 mins followed by substra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetLysine-specific demethylase 4C(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM314142(US10179769, Example 46 | 3-[(1,2,3,4-tetrahydronap...)
Affinity DataIC50: 12nMAssay Description:Inhibition of KDM4C (unknown origin) using biotinylated H3K9me3 peptide and alpha-ketoglutarate as substrate pretreated for 1 hr followed by substrat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetLysine-specific demethylase 4C(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM264020(2-[5-[(4- cyanophenyl)methoxy]pyrazol-1- yl]pyridi...)
Affinity DataIC50: 14nMAssay Description:Inhibition of KDM4C (unknown origin) preincubated with enzymeMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetLysine-specific demethylase 4C(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50538954(CHEMBL4646339)
Affinity DataIC50: 16nMAssay Description:Inhibition of KDM4C (unknown origin) using methylated H3 peptide as substrate by chemiluminescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetLysine-specific demethylase 4C(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50457156(CHEMBL4207071)
Affinity DataIC50: 17nMAssay Description:Inhibition of KDM4C (unknown origin) using biotinylated H3K9me3 peptide and alpha-ketoglutarate as substrate pretreated for 1 hr followed by substrat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetLysine-specific demethylase 4C(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM264025(2-(4-[2-(dimethylamino)ethyl]- 5-[(4- fluorophenyl...)
Affinity DataIC50: 19nMAssay Description:Inhibition of KDM4C (unknown origin) preincubated with enzymeMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetLysine-specific demethylase 4C(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50538953(CHEMBL1316847)
Affinity DataIC50: 19nMAssay Description:Inhibition of KDM4C (unknown origin) using methylated H3 peptide as substrate by chemiluminescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLysine-specific demethylase 4C(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM26113(pyridine-2,4-dicarboxylic acid | cid_10365 | pyrid...)
Affinity DataIC50: 19nMAssay Description:Inhibition of KDM4C (unknown origin)More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetLysine-specific demethylase 4C(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50454853(CHEMBL4205183)
Affinity DataIC50: 22nMAssay Description:Inhibition of KDM4C (unknown origin) expressed in Escherichia coli using biotinylated peptide as substrate pretreated for 15 mins followed by substra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetLysine-specific demethylase 4C(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50454849(CHEMBL4218675)
Affinity DataIC50: 23nMAssay Description:Inhibition of KDM4C (unknown origin) expressed in Escherichia coli using biotinylated peptide as substrate pretreated for 15 mins followed by substra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetLysine-specific demethylase 4C(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50454859(CHEMBL4206181)
Affinity DataIC50: 23nMAssay Description:Inhibition of KDM4C (unknown origin) expressed in Escherichia coli using biotinylated peptide as substrate pretreated for 15 mins followed by substra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetLysine-specific demethylase 4C(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM263975(2-{5-[(4-fluorobenzyl)oxy]-1H- pyrazol-1-yl}pyridi...)
Affinity DataIC50: 24nMAssay Description:Inhibition of KDM4C (unknown origin) preincubated with enzymeMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetLysine-specific demethylase 4C(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50454855(CHEMBL4215000)
Affinity DataIC50: 27nMAssay Description:Inhibition of KDM4C (unknown origin) expressed in Escherichia coli using biotinylated peptide as substrate pretreated for 15 mins followed by substra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetLysine-specific demethylase 4C(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50438921(CHEMBL1394266)
Affinity DataIC50: 29nMAssay Description:Inhibition of KDM4C (unknown origin) using methylated H3 peptide as substrate by chemiluminescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLysine-specific demethylase 4C(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50598660(CHEMBL5203308)
Affinity DataIC50: 33nMAssay Description:Inhibition of KDM4C (unknown origin) measured by AlphaScreen assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetLysine-specific demethylase 4C(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM191600(US9714230, 89 | 2-(5-((4-chloro-2-methylbenzyl)oxy...)
Affinity DataIC50: 35nMAssay Description:Inhibition of KDM4C (unknown origin) preincubated with enzymeMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLysine-specific demethylase 4C(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM293660(3-({[(1S)-6-[methyl(phenyl)amino]-1,2,3,4-tetrahyd...)
Affinity DataIC50: 35nMAssay Description:Inhibition of KDM4C (unknown origin) using biotinylated H3K9me3 peptide and alpha-ketoglutarate as substrate pretreated for 1 hr followed by substrat...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLysine-specific demethylase 4C(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM293660(3-({[(1S)-6-[methyl(phenyl)amino]-1,2,3,4-tetrahyd...)
Affinity DataIC50: 35nMAssay Description:Inhibition of KDM4C (unknown origin) using H3K9me3 as substrate and measured by LANCE TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetLysine-specific demethylase 4C(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM264012(2-[5-[(4-chloro-2- methoxyphenyl)methoxy]pyrazol- ...)
Affinity DataIC50: 38nMAssay Description:Inhibition of KDM4C (unknown origin) preincubated with enzymeMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetLysine-specific demethylase 4C(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50454848(CHEMBL4205285)
Affinity DataIC50: 38nMAssay Description:Inhibition of KDM4C (unknown origin) expressed in Escherichia coli using biotinylated peptide as substrate pretreated for 15 mins followed by substra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetLysine-specific demethylase 4C(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM264012(2-[5-[(4-chloro-2- methoxyphenyl)methoxy]pyrazol- ...)
Affinity DataIC50: 38nMAssay Description:TBDMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetLysine-specific demethylase 4C(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM191600(US9714230, 89 | 2-(5-((4-chloro-2-methylbenzyl)oxy...)
Affinity DataIC50: 41nMAssay Description:TBDMore data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetLysine-specific demethylase 4C(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50538950(CHEMBL4640696)
Affinity DataIC50: 42nMAssay Description:Inhibition of KDM4C (unknown origin) using methylated H3 peptide as substrate by chemiluminescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetLysine-specific demethylase 4C(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50454847(CHEMBL4203936)
Affinity DataIC50: 46nMAssay Description:Inhibition of KDM4C (unknown origin) expressed in Escherichia coli using biotinylated peptide as substrate pretreated for 15 mins followed by substra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetLysine-specific demethylase 4C(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50457157(CHEMBL4216399)
Affinity DataIC50: 48nMAssay Description:Inhibition of KDM4C (unknown origin) using biotinylated H3K9me3 peptide and alpha-ketoglutarate as substrate pretreated for 1 hr followed by substrat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetLysine-specific demethylase 4C(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50454858(CHEMBL4218774)
Affinity DataIC50: 53nMAssay Description:Inhibition of KDM4C (unknown origin) expressed in Escherichia coli using biotinylated peptide as substrate pretreated for 15 mins followed by substra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetLysine-specific demethylase 4C(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50158703(US9714230, 53 | CHEMBL3785832 | US9604961, Example...)
Affinity DataIC50: 54nMAssay Description:Inhibition of KDM4C (unknown origin) preincubated with enzymeMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLysine-specific demethylase 4C(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM670388(US20240139197, Compound 21)
Affinity DataIC50: 54nMAssay Description:TBDMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetLysine-specific demethylase 4C(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50454846(CHEMBL4211201)
Affinity DataIC50: 55nMAssay Description:Inhibition of KDM4C (unknown origin) expressed in Escherichia coli using biotinylated peptide as substrate pretreated for 15 mins followed by substra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetLysine-specific demethylase 4C(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50153331(CHEMBL3774552)
Affinity DataIC50: 63nMAssay Description:Inhibition of KDM4C (unknown origin) using H3K9Me3 peptide as substrate assessed as demethylation of substrate by Rapidfire mass spectrometric analys...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLysine-specific demethylase 4C(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50153330(CHEMBL3774859)
Affinity DataIC50: 63nMAssay Description:Inhibition of KDM4C (unknown origin) using H3K9Me3 peptide as substrate assessed as demethylation of substrate by Rapidfire mass spectrometric analys...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLysine-specific demethylase 4C(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50151392(CHEMBL3775262)
Affinity DataIC50: 64nMAssay Description:Inhibition of N-terminal His6-tagged KDM4C (1 to 352 residues) (unknown origin) expressed in Escherichia coli Rosetta 2(DE3)pLysS using biotinylated ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLysine-specific demethylase 4C(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50151392(CHEMBL3775262)
Affinity DataIC50: 64nMAssay Description:Inhibition of KDM4C (1 to 352 residues) (unknown origin) using biotin-tagged histone H3 (residues 1-21) lysine 9 trimethylated peptide as substrate i...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetLysine-specific demethylase 4C(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50151393(CHEMBL3775867)
Affinity DataIC50: 65nMAssay Description:Inhibition of N-terminal His6-tagged KDM4C (1 to 352 residues) (unknown origin) expressed in Escherichia coli Rosetta 2(DE3)pLysS using biotinylated ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLysine-specific demethylase 4C(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50454856(CHEMBL4208277)
Affinity DataIC50: 65nMAssay Description:Inhibition of KDM4C (unknown origin) expressed in Escherichia coli using biotinylated peptide as substrate pretreated for 15 mins followed by substra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetLysine-specific demethylase 4C(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM263978(2-{5-[(4-methoxybenzyl)oxy]-1H- pyrazol-1-yl}pyrid...)
Affinity DataIC50: 68nMAssay Description:Inhibition of KDM4C (unknown origin) preincubated with enzymeMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetLysine-specific demethylase 4C(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50151396(CHEMBL3775563)
Affinity DataIC50: 69nMAssay Description:Inhibition of N-terminal His6-tagged KDM4C (1 to 352 residues) (unknown origin) expressed in Escherichia coli Rosetta 2(DE3)pLysS using biotinylated ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLysine-specific demethylase 4C(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50495468(CHEMBL3108958)
Affinity DataIC50: 70nMAssay Description:Inhibition of recombinant JMJD2C (unknown origin) incubated for 15 mins prior to substrate addition by AlphaScreen methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetLysine-specific demethylase 4C(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM264021(2-[5-[(4-chloro-2- phenylmethoxyphenyl)methoxy] py...)
Affinity DataIC50: 74nMAssay Description:Inhibition of KDM4C (unknown origin) preincubated with enzymeMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetLysine-specific demethylase 4C(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM670395(US20240139197, Compound 37)
Affinity DataIC50: 74nMAssay Description:TBDMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetLysine-specific demethylase 4C(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM264030(2-[5-[(4-chloro-2- ethoxyphenyl)methoxy]pyrazol-1-...)
Affinity DataIC50: 78nMAssay Description:Inhibition of KDM4C (unknown origin) preincubated with enzymeMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetLysine-specific demethylase 4C(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM264030(2-[5-[(4-chloro-2- ethoxyphenyl)methoxy]pyrazol-1-...)
Affinity DataIC50: 78nMAssay Description:TBDMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

Displayed 1 to 50 (of 1884 total ) | Next | Last >>
Jump to: