Compile Data Set for Download or QSAR
Report error Found 29 of ic50 data for polymerid = 8230
TargetLysine-specific demethylase 3B(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM191598(KDOAM-20 | KDM5-C49 | 2-(((2-((2-(dimethylamino)et...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of recombinant KDM3B (842 to 1761 residues) (unknown origin) expressed in baculovirus infected sf9 cells using biotin-H3K9me as substrate ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLysine-specific demethylase 3B(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50158857(CHEMBL3787547)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of recombinant KDM3B (842 to 1761 residues) (unknown origin) expressed in baculovirus infected sf9 cells using biotin-H3K9me as substrate ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLysine-specific demethylase 3B(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50158858(CHEMBL3786409)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of recombinant KDM3B (842 to 1761 residues) (unknown origin) expressed in baculovirus infected sf9 cells using biotin-H3K9me as substrate ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLysine-specific demethylase 3B(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM293660(3-({[(1S)-6-[methyl(phenyl)amino]-1,2,3,4-tetrahyd...)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of KDM3B (unknown origin) using biotinylated H3K9me1 peptide and alpha-ketoglutarate as substrate measured after 20 mins by LANCE TR-FRET ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLysine-specific demethylase 3B(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50242878(CHEMBL4090908)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of KDM3B (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLysine-specific demethylase 3B(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM195608(CPI-455 | US20240139197, Compound 3)
Affinity DataIC50: 1.53E+4nMAssay Description:Inhibition of KDM3B (unknown origin) using ARTKQTAR(KMe1)STGGKAPRKQLA -NovaTagPEG-biotin/2-OG as substrate/co-factor by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLysine-specific demethylase 3B(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM195608(CPI-455 | US20240139197, Compound 3)
Affinity DataIC50: 1.53E+4nMAssay Description:TR-FRET assays similar to those described above for KDM5 enzymes were carried out with full-length KDM2B, KDM3B, KDM4C, KDM6A and KDM7B.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLysine-specific demethylase 3B(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM195608(CPI-455 | US20240139197, Compound 3)
Affinity DataIC50: 1.53E+4nMAssay Description:Inhibition of KDM3B (unknown origin) using ARTKQTAR(KMe1)STGGKAPRKQLA -NovaTagPEG-biotin/2-OG as substrate/co-factor by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLysine-specific demethylase 3B(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM195608(CPI-455 | US20240139197, Compound 3)
Affinity DataIC50: 2.50E+4nMAssay Description:TR-FRET assays similar to those described above for KDM5 enzymes were carried out with full-length KDM2B, KDM3B, KDM4C, KDM6A and KDM7B.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLysine-specific demethylase 3B(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM281089(US10022354, Example 29)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of recombinant human N-terminal FLAG-tagged KDM3B expressed in baculovirus infected Sf9 insect cells using H3K9me1 peptide as substrate af...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLysine-specific demethylase 3B(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM281138(US10022354, Example 78)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of recombinant human N-terminal FLAG-tagged KDM3B expressed in baculovirus infected Sf9 insect cells using H3K9me1 peptide as substrate af...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetLysine-specific demethylase 3B(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM60875(GSK-J1 | 3-((6-(4,5-Dihydro-1H-benzo[d]azepin-3(2H...)
Affinity DataIC50: 2.50E+4nMAssay Description:TR-FRET assays similar to those described above for KDM5 enzymes were carried out with full-length KDM2B, KDM3B, KDM4C, KDM6A and KDM7B.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLysine-specific demethylase 3B(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM195609(CPI-4203)
Affinity DataIC50: 2.50E+4nMAssay Description:TR-FRET assays similar to those described above for KDM5 enzymes were carried out with full-length KDM2B, KDM3B, KDM4C, KDM6A and KDM7B.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLysine-specific demethylase 3B(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50580328(CHEMBL5071515)
Affinity DataIC50: 2.67E+4nMAssay Description:Inhibition of human N-terminal His6-tagged KDM3B (L882 to S1761 residues) expressed in insect cells using H3K9(Me2) as substrate preincubated for 15 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetLysine-specific demethylase 3B(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50580322(CHEMBL5072902)
Affinity DataIC50: 4.76E+4nMAssay Description:Inhibition of human N-terminal His6-tagged KDM3B (L882 to S1761 residues) expressed in insect cells using H3K9(Me2) as substrate preincubated for 15 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetLysine-specific demethylase 3B(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50580320(CHEMBL5071002)
Affinity DataIC50: 5.12E+4nMAssay Description:Inhibition of human N-terminal His6-tagged KDM3B (L882 to S1761 residues) expressed in insect cells using H3K9(Me2) as substrate preincubated for 15 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetLysine-specific demethylase 3B(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50580317(CHEMBL5080728)
Affinity DataIC50: 5.32E+4nMAssay Description:Inhibition of human N-terminal His6-tagged KDM3B (L882 to S1761 residues) expressed in insect cells using H3K9(Me2) as substrate preincubated for 15 ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLysine-specific demethylase 3B(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50580325(CHEMBL5084638)
Affinity DataIC50: 5.42E+4nMAssay Description:Inhibition of human N-terminal His6-tagged KDM3B (L882 to S1761 residues) expressed in insect cells using H3K9(Me2) as substrate preincubated for 15 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetLysine-specific demethylase 3B(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50580324(CHEMBL5081435)
Affinity DataIC50: 5.62E+4nMAssay Description:Inhibition of human N-terminal His6-tagged KDM3B (L882 to S1761 residues) expressed in insect cells using H3K9(Me2) as substrate preincubated for 15 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails Article
PubMed
TargetLysine-specific demethylase 3B(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50580326(CHEMBL5070745)
Affinity DataIC50: 5.75E+4nMAssay Description:Inhibition of human N-terminal His6-tagged KDM3B (L882 to S1761 residues) expressed in insect cells using H3K9(Me2) as substrate preincubated for 15 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetLysine-specific demethylase 3B(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50580319(CHEMBL5083418)
Affinity DataIC50: 6.21E+4nMAssay Description:Inhibition of human N-terminal His6-tagged KDM3B (L882 to S1761 residues) expressed in insect cells using H3K9(Me2) as substrate preincubated for 15 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetLysine-specific demethylase 3B(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50580329(CHEMBL5084143)
Affinity DataIC50: 6.37E+4nMAssay Description:Inhibition of human N-terminal His6-tagged KDM3B (L882 to S1761 residues) expressed in insect cells using H3K9(Me2) as substrate preincubated for 15 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetLysine-specific demethylase 3B(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50580327(CHEMBL5089880)
Affinity DataIC50: 6.59E+4nMAssay Description:Inhibition of human N-terminal His6-tagged KDM3B (L882 to S1761 residues) expressed in insect cells using H3K9(Me2) as substrate preincubated for 15 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetLysine-specific demethylase 3B(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50580321(CHEMBL5091848)
Affinity DataIC50: 6.68E+4nMAssay Description:Inhibition of human N-terminal His6-tagged KDM3B (L882 to S1761 residues) expressed in insect cells using H3K9(Me2) as substrate preincubated for 15 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetLysine-specific demethylase 3B(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM223320(KDOAM-25)
Affinity DataIC50: 8.00E+4nMAssay Description:We previously described 4-carboxy-2-triazolopyridines as selective KDM2 inhibitors (England et al., 2014). In efforts to find alternative scaffolds b...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLysine-specific demethylase 3B(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50580323(CHEMBL5076580)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human N-terminal His6-tagged KDM3B (L882 to S1761 residues) expressed in insect cells using H3K9(Me2) as substrate preincubated for 15 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetLysine-specific demethylase 3B(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50576306(CHEMBL4849961)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of KDM3B (unknown origin) by Succinate-Glo assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetLysine-specific demethylase 3B(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50574750(CHEMBL4850758)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of KDM3B (unknown origin) by AlphaLISA assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetLysine-specific demethylase 3B(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50580318(CHEMBL5089117)
Affinity DataIC50: 1.06E+5nMAssay Description:Inhibition of human N-terminal His6-tagged KDM3B (L882 to S1761 residues) expressed in insect cells using H3K9(Me2) as substrate preincubated for 15 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed