Compile Data Set for Download or QSAR
Report error Found 1033 of ic50 data for polymerid = 808,50003589
TargetAngiopoietin-1 receptor(Human)
Xi'An Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50230178(CHEMBL4087541)
Affinity DataIC50: 0.130nMAssay Description:Inhibition of TIE-2 (unknown origin) after 60 mins by ADP-Glo assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAngiopoietin-1 receptor(Human)
Xi'An Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50230179(CHEMBL4103584)
Affinity DataIC50: 0.160nMAssay Description:Inhibition of TIE-2 (unknown origin) after 60 mins by ADP-Glo assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAngiopoietin-1 receptor(Human)
Xi'An Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50507550(CHEMBL4449700)
Affinity DataIC50: 0.260nMAssay Description:Inhibition of TIE2 (unknown origin) after 4 hrs by ADP-Glo reagent based luminescent assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetAngiopoietin-1 receptor(Human)
Xi'An Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50507542(CHEMBL4447552)
Affinity DataIC50: 0.280nMAssay Description:Inhibition of TIE2 (unknown origin) after 4 hrs by ADP-Glo reagent based luminescent assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetAngiopoietin-1 receptor(Human)
Xi'An Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50507536(CHEMBL4528844)
Affinity DataIC50: 0.300nMAssay Description:Inhibition of TIE2 (unknown origin) after 4 hrs by ADP-Glo reagent based luminescent assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetAngiopoietin-1 receptor(Human)
Xi'An Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50507538(CHEMBL4452256)
Affinity DataIC50: 0.360nMAssay Description:Inhibition of TIE2 (unknown origin) after 4 hrs by ADP-Glo reagent based luminescent assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetAngiopoietin-1 receptor(Human)
Xi'An Jiaotong University

Curated by ChEMBL
LigandPNGBDBM16673(Xarelto | BAY439006 | CHEMBL1336 | BAY 43-9006 | 4...)
Affinity DataIC50: 0.390nMAssay Description:Inhibition of TIE2 (unknown origin) after 4 hrs by ADP-Glo reagent based luminescent assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAngiopoietin-1 receptor(Human)
Xi'An Jiaotong University

Curated by ChEMBL
LigandPNGBDBM16673(Xarelto | BAY439006 | CHEMBL1336 | BAY 43-9006 | 4...)
Affinity DataIC50: 0.390nMAssay Description:Inhibition of Tie-2 (unknown origin) after 1 hrs by ADP-Glo luminescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAngiopoietin-1 receptor(Human)
Xi'An Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50507535(CHEMBL4570075)
Affinity DataIC50: 0.450nMAssay Description:Inhibition of TIE2 (unknown origin) after 4 hrs by ADP-Glo reagent based luminescent assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetAngiopoietin-1 receptor(Human)
Xi'An Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50230189(CHEMBL4066813)
Affinity DataIC50: 0.600nMAssay Description:Inhibition of TIE-2 (unknown origin) after 60 mins by ADP-Glo assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAngiopoietin-1 receptor(Human)
Xi'An Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50507541(CHEMBL4441465)
Affinity DataIC50: 0.730nMAssay Description:Inhibition of TIE2 (unknown origin) after 4 hrs by ADP-Glo reagent based luminescent assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetAngiopoietin-1 receptor(Human)
Xi'An Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50531745(CHEMBL4539395)
Affinity DataIC50: 0.820nMAssay Description:Inhibition of Tie-2 (unknown origin) after 1 hrs by ADP-Glo luminescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetAngiopoietin-1 receptor(Human)
Xi'An Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50512432(CHEMBL4589373)
Affinity DataIC50: 0.820nMAssay Description:Inhibition of Tie2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetAngiopoietin-1 receptor(Human)
Xi'An Jiaotong University

Curated by ChEMBL
LigandPNGBDBM16673(Xarelto | BAY439006 | CHEMBL1336 | BAY 43-9006 | 4...)
Affinity DataIC50: 0.830nMAssay Description:Inhibition of TIE-2 (unknown origin) after 60 mins by ADP-Glo assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAngiopoietin-1 receptor(Human)
Xi'An Jiaotong University

Curated by ChEMBL
LigandPNGBDBM14948(4-Methyl-3-(3-(2-(methylamino)pyrimidin-4-yl)pyrid...)
Affinity DataIC50: 1nMpH: 7.5 T: 2°CAssay Description:The assay uses purified enzyme interacting with biotinylated peptide substrate. HTRF is based on the proximity of europium cryptate (donor fluorophor...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAngiopoietin-1 receptor(Human)
Xi'An Jiaotong University

Curated by ChEMBL
LigandPNGBDBM14949(3-(2-aminoquinazolin-6-yl)-4-methyl-N-[3-(trifluor...)
Affinity DataIC50: 1nMpH: 7.5 T: 2°CAssay Description:The assay uses purified enzyme interacting with biotinylated peptide substrate. HTRF is based on the proximity of europium cryptate (donor fluorophor...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAngiopoietin-1 receptor(Human)
Xi'An Jiaotong University

Curated by ChEMBL
LigandPNGBDBM14974(N-{3-[3-(dimethylamino)propyl]-5-(trifluoromethyl)...)
Affinity DataIC50: 1nMpH: 7.5 T: 2°CAssay Description:The assay uses purified enzyme interacting with biotinylated peptide substrate. HTRF is based on the proximity of europium cryptate (donor fluorophor...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAngiopoietin-1 receptor(Human)
Xi'An Jiaotong University

Curated by ChEMBL
LigandPNGBDBM14948(4-Methyl-3-(3-(2-(methylamino)pyrimidin-4-yl)pyrid...)
Affinity DataIC50: 1nMpH: 7.5 T: 2°CAssay Description:The assay uses purified enzyme interacting with biotinylated peptide substrate. HTRF is based on the proximity of europium cryptate (donor fluorophor...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAngiopoietin-1 receptor(Human)
Xi'An Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50192705(1-(2-fluoro-5-methylphenyl)-3-{19-methyl-14-oxo-3-...)
Affinity DataIC50: 1nMAssay Description:Inhibition of Tie2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAngiopoietin-1 receptor(Human)
Xi'An Jiaotong University

Curated by ChEMBL
LigandPNGBDBM14974(N-{3-[3-(dimethylamino)propyl]-5-(trifluoromethyl)...)
Affinity DataIC50: 1nMAssay Description:Inhibition of Tie2 after 90 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAngiopoietin-1 receptor(Human)
Xi'An Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50207855(N-(3-isopropylphenyl)-4-methyl-3-(3-(4-(methylamin...)
Affinity DataIC50: 1nMAssay Description:Inhibition of Tie2 after 90 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAngiopoietin-1 receptor(Human)
Xi'An Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50207856(3-isopropyl-N-(4-methyl-3-(3-(2-(methylamino)pyrid...)
Affinity DataIC50: 1nMAssay Description:Inhibition of Tie2 after 90 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAngiopoietin-1 receptor(Human)
Xi'An Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50207852(3-isopropyl-N-(4-methyl-3-(3-(4-(methylamino)-1,3,...)
Affinity DataIC50: 1nMAssay Description:Inhibition of Tie2 after 90 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAngiopoietin-1 receptor(Human)
Xi'An Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50266148(N-(4-(3-(2-(methylamino)pyrimidin-4-yl)pyridin-2-y...)
Affinity DataIC50: 1nMAssay Description:Inhibition of Tie2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAngiopoietin-1 receptor(Human)
Xi'An Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50319571(N-(4-(3-(2-((1-ethylpiperidin-4-yl)methylamino)pyr...)
Affinity DataIC50: 1nMAssay Description:Inhibition of Tie2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAngiopoietin-1 receptor(Human)
Xi'An Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50266148(N-(4-(3-(2-(methylamino)pyrimidin-4-yl)pyridin-2-y...)
Affinity DataIC50: 1nMAssay Description:Inhibition of Tie2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAngiopoietin-1 receptor(Human)
Xi'An Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50375682(CHEMBL270057)
Affinity DataIC50: 1nMAssay Description:Inhibition of Tie2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAngiopoietin-1 receptor(Human)
Xi'An Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50399540(FORETINIB | US10464902, Foretinib | US10882853, Co...)
Affinity DataIC50: 1.10nMAssay Description:Inhibition of TIE-2 (unknown origin) using poly (Glu, Tyr) 4:1 as substrate after 2 hrs in presence of [33P]-gamma-ATP by microbeta scintillation cou...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAngiopoietin-1 receptor(Human)
Xi'An Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50230188(CHEMBL4085653)
Affinity DataIC50: 1.10nMAssay Description:Inhibition of TIE-2 (unknown origin) after 60 mins by ADP-Glo assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAngiopoietin-1 receptor(Human)
Xi'An Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50363397(CHEMBL1946170 | REGORAFENIB | US10183928, Regorafe...)
Affinity DataIC50: 1.5nMAssay Description:Inhibition of GST-tagged TIE2 (unknown origin) using biotin-Ahx-EPKDDAYPLYSDFG peptide as substrate by HTRF methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAngiopoietin-1 receptor(Human)
Xi'An Jiaotong University

Curated by ChEMBL
LigandPNGBDBM35317(CHEMBL212964 | 4-Methyl-3-(2-(methylamino)quinazol...)
Affinity DataIC50: 1.80nMAssay Description:The in vitro kinase activities of wild type or mutants were determined by measuring phosphorylation of biotinylated-MEK protein using Perkin-Elmer s ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAngiopoietin-1 receptor(Human)
Xi'An Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50531753(CHEMBL4476000)
Affinity DataIC50: 1.80nMAssay Description:Inhibition of Tie-2 (unknown origin) after 1 hrs by ADP-Glo luminescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetAngiopoietin-1 receptor(Human)
Xi'An Jiaotong University

Curated by ChEMBL
LigandPNGBDBM5815(3-{4-[4-amino-6-(4-methoxyphenyl)furo[2,3-d]pyrimi...)
Affinity DataIC50: 2nMpH: 7.5 T: 2°CAssay Description:The assay was using baculovirus-expressed recombinant protein kinase purified as the intracellular domain fused by GST tag, interacting with biotinyl...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAngiopoietin-1 receptor(Human)
Xi'An Jiaotong University

Curated by ChEMBL
LigandPNGBDBM14967(3-(2-(3H-Imidazo[4,5-b]pyridin-6-yl)ethynyl)-4-met...)
Affinity DataIC50: 2nMpH: 7.5 T: 2°CAssay Description:The assay uses purified enzyme interacting with biotinylated peptide substrate. HTRF is based on the proximity of europium cryptate (donor fluorophor...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetAngiopoietin-1 receptor(Human)
Xi'An Jiaotong University

Curated by ChEMBL
LigandPNGBDBM14949(3-(2-aminoquinazolin-6-yl)-4-methyl-N-[3-(trifluor...)
Affinity DataIC50: 2nMAssay Description:The assay involves the phosphorylation of a biotinylated substrate and the detection of this phosphorylation after the addition of a streptavidin-all...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAngiopoietin-1 receptor(Human)
Xi'An Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50266221(N-[3-methyl-4-({3-[2-(methylamino)pyrimidin-4-yl]p...)
Affinity DataIC50: 2nMAssay Description:Inhibition of Tie2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAngiopoietin-1 receptor(Human)
Xi'An Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50192712(1-methyl-3-{19-methyl-14-oxo-3-propyl-3,13,19,20-t...)
Affinity DataIC50: 2nMAssay Description:Inhibition of Tie2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAngiopoietin-1 receptor(Human)
Xi'An Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50192714(1-(4-methoxyphenyl)-3-{19-methyl-14-oxo-3-propyl-3...)
Affinity DataIC50: 2nMAssay Description:Inhibition of Tie2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAngiopoietin-1 receptor(Human)
Xi'An Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50192709(1-(3-fluorophenyl)-3-{19-methyl-14-oxo-3-propyl-3,...)
Affinity DataIC50: 2nMAssay Description:Inhibition of Tie2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAngiopoietin-1 receptor(Human)
Xi'An Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50192722(1-(4-fluorophenyl)-3-{19-methyl-14-oxo-3-propyl-3,...)
Affinity DataIC50: 2nMAssay Description:Inhibition of Tie2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAngiopoietin-1 receptor(Human)
Xi'An Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50192708(1-(2-fluorophenyl)-3-{19-methyl-14-oxo-3-propyl-3,...)
Affinity DataIC50: 2nMAssay Description:Inhibition of Tie2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAngiopoietin-1 receptor(Human)
Xi'An Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50207850(3-isopropyl-N-(4-methyl-3-(3-(2-(methylamino)pyrim...)
Affinity DataIC50: 2nMAssay Description:Inhibition of Tie2 after 90 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAngiopoietin-1 receptor(Human)
Xi'An Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50236270(1-(4-(4-amino-6-(4-methoxyphenyl)furo[2,3-d]pyrimi...)
Affinity DataIC50: 2nMAssay Description:Inhibition of human recombinant TIE2 by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAngiopoietin-1 receptor(Human)
Xi'An Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50266221(N-[3-methyl-4-({3-[2-(methylamino)pyrimidin-4-yl]p...)
Affinity DataIC50: 2nMAssay Description:Inhibition of Tie2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAngiopoietin-1 receptor(Human)
Xi'An Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50319572(N-(4-(3-(2-(2-(1-methylpyrrolidin-2-yl)ethylamino)...)
Affinity DataIC50: 2nMAssay Description:Inhibition of Tie2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAngiopoietin-1 receptor(Human)
Xi'An Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50266221(N-[3-methyl-4-({3-[2-(methylamino)pyrimidin-4-yl]p...)
Affinity DataIC50: 2nMAssay Description:Inhibition of Tie2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAngiopoietin-1 receptor(Human)
Xi'An Jiaotong University

Curated by ChEMBL
LigandPNGBDBM14949(3-(2-aminoquinazolin-6-yl)-4-methyl-N-[3-(trifluor...)
Affinity DataIC50: 2nMAssay Description:Inhibition of Tie2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAngiopoietin-1 receptor(Human)
Xi'An Jiaotong University

Curated by ChEMBL
LigandPNGBDBM5815(3-{4-[4-amino-6-(4-methoxyphenyl)furo[2,3-d]pyrimi...)
Affinity DataIC50: 2nMAssay Description:Inhibition of Tie2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAngiopoietin-1 receptor(Human)
Xi'An Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50230174(CHEMBL4085495)
Affinity DataIC50: 2nMAssay Description:Inhibition of TIE-2 (unknown origin) after 60 mins by ADP-Glo assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAngiopoietin-1 receptor(Human)
Xi'An Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50283033(CHEMBL4160854)
Affinity DataIC50: 2.10nMAssay Description:Inhibition of TIE2 (unknown origin) after 4 hrs by ADP-Glo assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
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