Compile Data Set for Download or QSAR
Report error Found 15 of ic50 data for polymerid = 8021
TargetArachidonate 15-lipoxygenase(Pseudomonas aeruginosa)
University of California Santa Cruz

LigandPNGBDBM50329323(4-(5-(Naphthalen-1-yl)-1,3,4-oxadiazol-2-ylthio)bu...)
Affinity DataIC50: 10nMpH: 7.0 T: 2°CAssay Description:The one-point inhibition percentages were determined for human LOX inhibitors by following the formation of the conjugated diene product at 234 nm (&...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetArachidonate 15-lipoxygenase(Pseudomonas aeruginosa)
University of California Santa Cruz

LigandPNGBDBM32020(LOX inhibitor, N/A | 4-[4-(3,4-dihydroxyphenyl)-2,...)
Affinity DataIC50: 500nMpH: 7.0 T: 2°CAssay Description:The one-point inhibition percentages were determined for human LOX inhibitors by following the formation of the conjugated diene product at 234 nm (&...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetArachidonate 15-lipoxygenase(Pseudomonas aeruginosa)
University of California Santa Cruz

LigandPNGBDBM190652(PT171 | LOX inhibitor, 13)
Affinity DataIC50: 520nMpH: 7.0 T: 2°CAssay Description:The one-point inhibition percentages were determined for human LOX inhibitors by following the formation of the conjugated diene product at 234 nm (&...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetArachidonate 15-lipoxygenase(Pseudomonas aeruginosa)
University of California Santa Cruz

LigandPNGBDBM190651(PT113 | LOX inhibitor, 5)
Affinity DataIC50: 1.00E+3nMpH: 7.0 T: 2°CAssay Description:The one-point inhibition percentages were determined for human LOX inhibitors by following the formation of the conjugated diene product at 234 nm (&...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetArachidonate 15-lipoxygenase(Pseudomonas aeruginosa)
University of California Santa Cruz

LigandPNGBDBM190650(PT91 | LOX inhibitor, MLS000545091)
Affinity DataIC50: 2.60E+3nMpH: 7.0 T: 2°CAssay Description:The one-point inhibition percentages were determined for human LOX inhibitors by following the formation of the conjugated diene product at 234 nm (&...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails Article
PubMed
TargetArachidonate 15-lipoxygenase(Pseudomonas aeruginosa)
University of California Santa Cruz

LigandPNGBDBM26948(CHEMBL46516 | cid_3396 | FLUSPIRILENE | 8-[4,4-bis...)
Affinity DataIC50: 4.10E+3nMT: 2°CAssay Description:Briefly, 3 uL of enzyme (approximately 20 nM LoxA, final concentration) or buffer (no-enzyme control) was dispensed into 1536-well Greiner black clea...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetArachidonate 15-lipoxygenase(Pseudomonas aeruginosa)
University of California Santa Cruz

LigandPNGBDBM50017702(cid_6365505 | 1-(bis(4-fluorophenyl)methyl)-4-cinn...)
Affinity DataIC50: 4.50E+3nMT: 2°CAssay Description:Briefly, 3 uL of enzyme (approximately 20 nM LoxA, final concentration) or buffer (no-enzyme control) was dispensed into 1536-well Greiner black clea...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetArachidonate 15-lipoxygenase(Pseudomonas aeruginosa)
University of California Santa Cruz

LigandPNGBDBM50334150(1-(1-(4,4-bis(4-fluorophenyl)butyl)piperidin-4-yl)...)
Affinity DataIC50: 5.80E+3nMT: 2°CAssay Description:Briefly, 3 uL of enzyme (approximately 20 nM LoxA, final concentration) or buffer (no-enzyme control) was dispensed into 1536-well Greiner black clea...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetArachidonate 15-lipoxygenase(Pseudomonas aeruginosa)
University of California Santa Cruz

LigandPNGBDBM20607((2-{4-[(1Z)-1,2-diphenylbut-1-en-1-yl]phenoxy}ethy...)
Affinity DataIC50: 6.70E+3nMT: 2°CAssay Description:Briefly, 3 uL of enzyme (approximately 20 nM LoxA, final concentration) or buffer (no-enzyme control) was dispensed into 1536-well Greiner black clea...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetArachidonate 15-lipoxygenase(Pseudomonas aeruginosa)
University of California Santa Cruz

LigandPNGBDBM22165(Vanoxerine | CHEMBL542933 | GBR-12909 | CHEMBL5438...)
Affinity DataIC50: 8.00E+3nMT: 2°CAssay Description:Briefly, 3 uL of enzyme (approximately 20 nM LoxA, final concentration) or buffer (no-enzyme control) was dispensed into 1536-well Greiner black clea...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetArachidonate 15-lipoxygenase(Pseudomonas aeruginosa)
University of California Santa Cruz

LigandPNGBDBM22873(Bactil | CHEMBL305660 | 1-(4-tert-butylphenyl)-4-[...)
Affinity DataIC50: 1.01E+4nMT: 2°CAssay Description:Briefly, 3 uL of enzyme (approximately 20 nM LoxA, final concentration) or buffer (no-enzyme control) was dispensed into 1536-well Greiner black clea...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetArachidonate 15-lipoxygenase(Pseudomonas aeruginosa)
University of California Santa Cruz

LigandPNGBDBM21383(6-[4-(2-phenylphenyl)piperazin-1-yl]-N-(1,2,3,4-te...)
Affinity DataIC50: 1.14E+4nMT: 2°CAssay Description:Briefly, 3 uL of enzyme (approximately 20 nM LoxA, final concentration) or buffer (no-enzyme control) was dispensed into 1536-well Greiner black clea...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetArachidonate 15-lipoxygenase(Pseudomonas aeruginosa)
University of California Santa Cruz

LigandPNGBDBM79021(Sertraline | SMR000466298 | cid_63009 | (1S,4S)-4-...)
Affinity DataIC50: 1.31E+4nMT: 2°CAssay Description:Briefly, 3 uL of enzyme (approximately 20 nM LoxA, final concentration) or buffer (no-enzyme control) was dispensed into 1536-well Greiner black clea...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetArachidonate 15-lipoxygenase(Pseudomonas aeruginosa)
University of California Santa Cruz

LigandPNGBDBM50017712(Apoplon | 3,4,5-trimethoxybenzoyl methyl reserpate...)
Affinity DataIC50: 1.38E+4nMT: 2°CAssay Description:Briefly, 3 uL of enzyme (approximately 20 nM LoxA, final concentration) or buffer (no-enzyme control) was dispensed into 1536-well Greiner black clea...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetArachidonate 15-lipoxygenase(Pseudomonas aeruginosa)
University of California Santa Cruz

LigandPNGBDBM50092228(7-Cyclopentyl-5-(4-phenoxy-phenyl)-7H-pyrrolo[2,3-...)
Affinity DataIC50: 1.62E+4nMT: 2°CAssay Description:Briefly, 3 uL of enzyme (approximately 20 nM LoxA, final concentration) or buffer (no-enzyme control) was dispensed into 1536-well Greiner black clea...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed