Compile Data Set for Download or QSAR
Report error Found 1202 of ic50 data for polymerid = 7858,50006570
TargetPoly [ADP-ribose] polymerase tankyrase-2(Human)
University of Bath

Curated by ChEMBL
LigandPNGBDBM50234915(CHEMBL4069447)
Affinity DataIC50: 0.100nMAssay Description:Inhibition of recombinant human N-terminal His-GST-tagged TNKS2 (849 to 1166 residues) expressed in baculovirus infected Sf9 cells using biotinylated...More data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetPoly [ADP-ribose] polymerase tankyrase-2(Human)
University of Bath

Curated by ChEMBL
LigandPNGBDBM50234915(CHEMBL4069447)
Affinity DataIC50: 0.100nMAssay Description:Inhibition of recombinant human N-terminal His-GST-tagged TNKS2 (849 to 1166 residues) expressed in baculovirus infected Sf9 cells using biotinylated...More data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetPoly [ADP-ribose] polymerase tankyrase-2(Human)
University of Bath

Curated by ChEMBL
LigandPNGBDBM50234915(CHEMBL4069447)
Affinity DataIC50: 0.100nMAssay Description:Inhibition of TNKS2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetPoly [ADP-ribose] polymerase tankyrase-2(Human)
University of Bath

Curated by ChEMBL
LigandPNGBDBM50234915(CHEMBL4069447)
Affinity DataIC50: 0.100nMAssay Description:Inhibition of human TNKS2 (873 to 1162 residues) measured after 15 hrs in presence of NAD+ by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails
PubMedPDB3D3D Structure (crystal)
TargetPoly [ADP-ribose] polymerase tankyrase-2(Human)
University of Bath

Curated by ChEMBL
LigandPNGBDBM50169061(CHEMBL3805393)
Affinity DataIC50: 0.160nMAssay Description:Inhibition of GST-tagged TNKS2 (873 to 1166 residues) (unknown origin) autoparsylation using biotinylated NAD incubated for 1 hr by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPoly [ADP-ribose] polymerase tankyrase-2(Human)
University of Bath

Curated by ChEMBL
LigandPNGBDBM50169056(CHEMBL3806163)
Affinity DataIC50: 0.170nMAssay Description:Inhibition of GST-tagged TNKS2 (873 to 1166 residues) (unknown origin) autoparsylation using biotinylated NAD incubated for 1 hr by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPoly [ADP-ribose] polymerase tankyrase-2(Human)
University of Bath

Curated by ChEMBL
LigandPNGBDBM50169057(CHEMBL3805896)
Affinity DataIC50: 0.180nMAssay Description:Inhibition of GST-tagged TNKS2 (873 to 1166 residues) (unknown origin) autoparsylation using biotinylated NAD incubated for 1 hr by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPoly [ADP-ribose] polymerase tankyrase-2(Human)
University of Bath

Curated by ChEMBL
LigandPNGBDBM50169060(CHEMBL3804939)
Affinity DataIC50: 0.190nMAssay Description:Inhibition of GST-tagged TNKS2 (873 to 1166 residues) (unknown origin) autoparsylation using biotinylated NAD incubated for 1 hr by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPoly [ADP-ribose] polymerase tankyrase-2(Human)
University of Bath

Curated by ChEMBL
LigandPNGBDBM435386(US10570116, Compound C2)
Affinity DataIC50: 0.190nMAssay Description:TNKS 1 and 2: The activity ELISA is performed in 384 well Glutathione coated microtiter plates (Express capture Glutathione coated plate, Biocat, Hei...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetPoly [ADP-ribose] polymerase tankyrase-2(Human)
University of Bath

Curated by ChEMBL
LigandPNGBDBM50544643(CHEMBL4634919)
Affinity DataIC50: 0.190nMAssay Description:Inhibition of human GST-tagged tankyrase 2 autophosphorylationMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetPoly [ADP-ribose] polymerase tankyrase-2(Human)
University of Bath

Curated by ChEMBL
LigandPNGBDBM50234916(CHEMBL4098188)
Affinity DataIC50: 0.200nMAssay Description:Inhibition of recombinant human N-terminal His-GST-tagged TNKS2 (849 to 1166 residues) expressed in baculovirus infected Sf9 cells using biotinylated...More data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetPoly [ADP-ribose] polymerase tankyrase-2(Human)
University of Bath

Curated by ChEMBL
LigandPNGBDBM435395(US10570116, Compound C6)
Affinity DataIC50: 0.200nMAssay Description:TNKS 1 and 2: The activity ELISA is performed in 384 well Glutathione coated microtiter plates (Express capture Glutathione coated plate, Biocat, Hei...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetPoly [ADP-ribose] polymerase tankyrase-2(Human)
University of Bath

Curated by ChEMBL
LigandPNGBDBM50234916(CHEMBL4098188)
Affinity DataIC50: 0.200nMAssay Description:Inhibition of human TNKS2 (873 to 1162 residues) measured after 15 hrs in presence of NAD+ by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails
PubMedPDB3D3D Structure (crystal)
TargetPoly [ADP-ribose] polymerase tankyrase-2(Human)
University of Bath

Curated by ChEMBL
LigandPNGBDBM50234916(CHEMBL4098188)
Affinity DataIC50: 0.204nMAssay Description:Inhibition of recombinant human N-terminal His-GST-tagged TNKS2 (849 to 1166 residues) expressed in baculovirus infected Sf9 cells using biotinylated...More data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetPoly [ADP-ribose] polymerase tankyrase-2(Human)
University of Bath

Curated by ChEMBL
LigandPNGBDBM435441(US10570116, Compound C49)
Affinity DataIC50: 0.210nMAssay Description:TNKS 1 and 2: The activity ELISA is performed in 384 well Glutathione coated microtiter plates (Express capture Glutathione coated plate, Biocat, Hei...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetPoly [ADP-ribose] polymerase tankyrase-2(Human)
University of Bath

Curated by ChEMBL
LigandPNGBDBM435439(US10570116, Compound C47)
Affinity DataIC50: 0.220nMAssay Description:TNKS 1 and 2: The activity ELISA is performed in 384 well Glutathione coated microtiter plates (Express capture Glutathione coated plate, Biocat, Hei...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetPoly [ADP-ribose] polymerase tankyrase-2(Human)
University of Bath

Curated by ChEMBL
LigandPNGBDBM435442(US10570116, Compound C50)
Affinity DataIC50: 0.240nMAssay Description:TNKS 1 and 2: The activity ELISA is performed in 384 well Glutathione coated microtiter plates (Express capture Glutathione coated plate, Biocat, Hei...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetPoly [ADP-ribose] polymerase tankyrase-2(Human)
University of Bath

Curated by ChEMBL
LigandPNGBDBM435444(US10570116, Compound C52)
Affinity DataIC50: 0.25nMAssay Description:TNKS 1 and 2: The activity ELISA is performed in 384 well Glutathione coated microtiter plates (Express capture Glutathione coated plate, Biocat, Hei...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetPoly [ADP-ribose] polymerase tankyrase-2(Human)
University of Bath

Curated by ChEMBL
LigandPNGBDBM50544642(CHEMBL4632401)
Affinity DataIC50: 0.25nMAssay Description:Inhibition of human GST-tagged tankyrase 2 autophosphorylationMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetPoly [ADP-ribose] polymerase tankyrase-2(Human)
University of Bath

Curated by ChEMBL
LigandPNGBDBM50544640(CHEMBL4640008)
Affinity DataIC50: 0.260nMAssay Description:Inhibition of human GST-tagged tankyrase 2 autophosphorylationMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetPoly [ADP-ribose] polymerase tankyrase-2(Human)
University of Bath

Curated by ChEMBL
LigandPNGBDBM50544645(CHEMBL4643690)
Affinity DataIC50: 0.270nMAssay Description:Inhibition of human GST-tagged tankyrase 2 autophosphorylationMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetPoly [ADP-ribose] polymerase tankyrase-2(Human)
University of Bath

Curated by ChEMBL
LigandPNGBDBM50169058(CHEMBL3806049)
Affinity DataIC50: 0.280nMAssay Description:Inhibition of GST-tagged TNKS2 (873 to 1166 residues) (unknown origin) autoparsylation using biotinylated NAD incubated for 1 hr by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPoly [ADP-ribose] polymerase tankyrase-2(Human)
University of Bath

Curated by ChEMBL
LigandPNGBDBM50544644(CHEMBL4639702)
Affinity DataIC50: 0.290nMAssay Description:Inhibition of human GST-tagged tankyrase 2 autophosphorylationMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetPoly [ADP-ribose] polymerase tankyrase-2(Human)
University of Bath

Curated by ChEMBL
LigandPNGBDBM50540762(CHEMBL4638701)
Affinity DataIC50: 0.300nMAssay Description:Inhibition of full length human N-terminal GST-tagged TNKS2 ADP-ART catalytic domain (1001 to 1327 residues) using histone H2A as substrate incubated...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPoly [ADP-ribose] polymerase tankyrase-2(Human)
University of Bath

Curated by ChEMBL
LigandPNGBDBM435430(US10570116, Compound C38)
Affinity DataIC50: 0.320nMAssay Description:TNKS 1 and 2: The activity ELISA is performed in 384 well Glutathione coated microtiter plates (Express capture Glutathione coated plate, Biocat, Hei...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetPoly [ADP-ribose] polymerase tankyrase-2(Human)
University of Bath

Curated by ChEMBL
LigandPNGBDBM435409(US10570116, Compound C17)
Affinity DataIC50: 0.330nMAssay Description:TNKS 1 and 2: The activity ELISA is performed in 384 well Glutathione coated microtiter plates (Express capture Glutathione coated plate, Biocat, Hei...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetPoly [ADP-ribose] polymerase tankyrase-2(Human)
University of Bath

Curated by ChEMBL
LigandPNGBDBM435410(US10570116, Compound C18)
Affinity DataIC50: 0.360nMAssay Description:TNKS 1 and 2: The activity ELISA is performed in 384 well Glutathione coated microtiter plates (Express capture Glutathione coated plate, Biocat, Hei...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetPoly [ADP-ribose] polymerase tankyrase-2(Human)
University of Bath

Curated by ChEMBL
LigandPNGBDBM435384(US10570116, Compound C1)
Affinity DataIC50: 0.370nMAssay Description:TNKS 1 and 2: The activity ELISA is performed in 384 well Glutathione coated microtiter plates (Express capture Glutathione coated plate, Biocat, Hei...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetPoly [ADP-ribose] polymerase tankyrase-2(Human)
University of Bath

Curated by ChEMBL
LigandPNGBDBM435403(US10570116, Compound C11)
Affinity DataIC50: 0.400nMAssay Description:TNKS 1 and 2: The activity ELISA is performed in 384 well Glutathione coated microtiter plates (Express capture Glutathione coated plate, Biocat, Hei...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetPoly [ADP-ribose] polymerase tankyrase-2(Human)
University of Bath

Curated by ChEMBL
LigandPNGBDBM435408(US10570116, Compound C16)
Affinity DataIC50: 0.410nMAssay Description:TNKS 1 and 2: The activity ELISA is performed in 384 well Glutathione coated microtiter plates (Express capture Glutathione coated plate, Biocat, Hei...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetPoly [ADP-ribose] polymerase tankyrase-2(Human)
University of Bath

Curated by ChEMBL
LigandPNGBDBM50544641(CHEMBL4645574)
Affinity DataIC50: 0.440nMAssay Description:Inhibition of human GST-tagged tankyrase 2 autophosphorylationMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetPoly [ADP-ribose] polymerase tankyrase-2(Human)
University of Bath

Curated by ChEMBL
LigandPNGBDBM435393(US10570116, Compound C4)
Affinity DataIC50: 0.450nMAssay Description:TNKS 1 and 2: The activity ELISA is performed in 384 well Glutathione coated microtiter plates (Express capture Glutathione coated plate, Biocat, Hei...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetPoly [ADP-ribose] polymerase tankyrase-2(Human)
University of Bath

Curated by ChEMBL
LigandPNGBDBM435425(US10570116, Compound C33)
Affinity DataIC50: 0.450nMAssay Description:TNKS 1 and 2: The activity ELISA is performed in 384 well Glutathione coated microtiter plates (Express capture Glutathione coated plate, Biocat, Hei...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetPoly [ADP-ribose] polymerase tankyrase-2(Human)
University of Bath

Curated by ChEMBL
LigandPNGBDBM435426(US10570116, Compound C34)
Affinity DataIC50: 0.5nMAssay Description:TNKS 1 and 2: The activity ELISA is performed in 384 well Glutathione coated microtiter plates (Express capture Glutathione coated plate, Biocat, Hei...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetPoly [ADP-ribose] polymerase tankyrase-2(Human)
University of Bath

Curated by ChEMBL
LigandPNGBDBM50505331(CHEMBL4458129)
Affinity DataIC50: 0.5nMAssay Description:Inhibition of GST tagged-TEV cleavage site-fused human recombinant TNKS2 (873 to 1166 residues) expressed in baculovirus infected sf9 cells assessed ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetPoly [ADP-ribose] polymerase tankyrase-2(Human)
University of Bath

Curated by ChEMBL
LigandPNGBDBM435399(US10570116, Compound C8)
Affinity DataIC50: 0.530nMAssay Description:TNKS 1 and 2: The activity ELISA is performed in 384 well Glutathione coated microtiter plates (Express capture Glutathione coated plate, Biocat, Hei...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetPoly [ADP-ribose] polymerase tankyrase-2(Human)
University of Bath

Curated by ChEMBL
LigandPNGBDBM435437(US10570116, Compound C45)
Affinity DataIC50: 0.550nMAssay Description:TNKS 1 and 2: The activity ELISA is performed in 384 well Glutathione coated microtiter plates (Express capture Glutathione coated plate, Biocat, Hei...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetPoly [ADP-ribose] polymerase tankyrase-2(Human)
University of Bath

Curated by ChEMBL
LigandPNGBDBM435424(US10570116, Compound C32)
Affinity DataIC50: 0.560nMAssay Description:TNKS 1 and 2: The activity ELISA is performed in 384 well Glutathione coated microtiter plates (Express capture Glutathione coated plate, Biocat, Hei...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetPoly [ADP-ribose] polymerase tankyrase-2(Human)
University of Bath

Curated by ChEMBL
LigandPNGBDBM435422(US10570116, Compound C30)
Affinity DataIC50: 0.570nMAssay Description:TNKS 1 and 2: The activity ELISA is performed in 384 well Glutathione coated microtiter plates (Express capture Glutathione coated plate, Biocat, Hei...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetPoly [ADP-ribose] polymerase tankyrase-2(Human)
University of Bath

Curated by ChEMBL
LigandPNGBDBM435411(US10570116, Compound C19)
Affinity DataIC50: 0.580nMAssay Description:TNKS 1 and 2: The activity ELISA is performed in 384 well Glutathione coated microtiter plates (Express capture Glutathione coated plate, Biocat, Hei...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetPoly [ADP-ribose] polymerase tankyrase-2(Human)
University of Bath

Curated by ChEMBL
LigandPNGBDBM435396(US10570116, Compound C7)
Affinity DataIC50: 0.590nMAssay Description:TNKS 1 and 2: The activity ELISA is performed in 384 well Glutathione coated microtiter plates (Express capture Glutathione coated plate, Biocat, Hei...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetPoly [ADP-ribose] polymerase tankyrase-2(Human)
University of Bath

Curated by ChEMBL
LigandPNGBDBM50232346(CHEMBL4101890)
Affinity DataIC50: 0.600nMAssay Description:Inhibition of recombinant human TNKS2 ADP-ribosyltransferase domain expressed in Escherichia coli BL21(DE3) preincubated for 15 mins followed by biot...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPoly [ADP-ribose] polymerase tankyrase-2(Human)
University of Bath

Curated by ChEMBL
LigandPNGBDBM50232346(CHEMBL4101890)
Affinity DataIC50: 0.600nMAssay Description:Inhibition of recombinant human TNKS2 ADP-ribosyltransferase domain expressed in Escherichia coli BL21(DE3) preincubated for 15 mins followed by biot...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPoly [ADP-ribose] polymerase tankyrase-2(Human)
University of Bath

Curated by ChEMBL
LigandPNGBDBM435431(US10570116, Compound C39)
Affinity DataIC50: 0.610nMAssay Description:TNKS 1 and 2: The activity ELISA is performed in 384 well Glutathione coated microtiter plates (Express capture Glutathione coated plate, Biocat, Hei...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetPoly [ADP-ribose] polymerase tankyrase-2(Human)
University of Bath

Curated by ChEMBL
LigandPNGBDBM435435(US10570116, Compound C43)
Affinity DataIC50: 0.630nMAssay Description:TNKS 1 and 2: The activity ELISA is performed in 384 well Glutathione coated microtiter plates (Express capture Glutathione coated plate, Biocat, Hei...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetPoly [ADP-ribose] polymerase tankyrase-2(Human)
University of Bath

Curated by ChEMBL
LigandPNGBDBM435445(US10570116, Compound C53)
Affinity DataIC50: 0.690nMAssay Description:TNKS 1 and 2: The activity ELISA is performed in 384 well Glutathione coated microtiter plates (Express capture Glutathione coated plate, Biocat, Hei...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetPoly [ADP-ribose] polymerase tankyrase-2(Human)
University of Bath

Curated by ChEMBL
LigandPNGBDBM50505332(CHEMBL4567515)
Affinity DataIC50: 0.700nMAssay Description:Inhibition of GST tagged-TEV cleavage site-fused human recombinant TNKS2 (873 to 1166 residues) expressed in baculovirus infected sf9 cells assessed ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetPoly [ADP-ribose] polymerase tankyrase-2(Human)
University of Bath

Curated by ChEMBL
LigandPNGBDBM435443(US10570116, Compound C51)
Affinity DataIC50: 0.720nMAssay Description:TNKS 1 and 2: The activity ELISA is performed in 384 well Glutathione coated microtiter plates (Express capture Glutathione coated plate, Biocat, Hei...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetPoly [ADP-ribose] polymerase tankyrase-2(Human)
University of Bath

Curated by ChEMBL
LigandPNGBDBM435412(US10570116, Compound C20)
Affinity DataIC50: 0.730nMAssay Description:TNKS 1 and 2: The activity ELISA is performed in 384 well Glutathione coated microtiter plates (Express capture Glutathione coated plate, Biocat, Hei...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetPoly [ADP-ribose] polymerase tankyrase-2(Human)
University of Bath

Curated by ChEMBL
LigandPNGBDBM50579971(CHEMBL5070513 | US11926614, Example 82)
Affinity DataIC50: 0.730nMAssay Description:Inhibition of recombinant human TNKS2 (873 to 1162 residues) incubated for 20 hrs in presence of NADMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
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