Compile Data Set for Download or QSAR
Report error Found 296 of ic50 data for polymerid = 7752
TargetProstaglandin E synthase 2(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50168766(3-(1-(4-chlorobenzyl)-5-(2-fluoro-2'-methylbipheny...)
Affinity DataIC50: 3nMAssay Description:Inhibitory concentration against human prostaglandin E2 synthase (mPGES-1)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin E synthase 2(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50168776(3-[1-(4-Chloro-benzyl)-5-(2'-chloro-2-fluoro-biphe...)
Affinity DataIC50: 4nMAssay Description:Inhibitory concentration against human prostaglandin E2 synthase (mPGES-1)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin E synthase 2(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50168760(3-(1-(4-chlorobenzyl)-5-(2-fluoro-2'-methoxybiphen...)
Affinity DataIC50: 5nMAssay Description:Inhibitory concentration against human prostaglandin E2 synthase (mPGES-1)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin E synthase 2(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50168785(3-[5-(2'-Acetyl-2-fluoro-biphenyl-4-yl)-1-(4-chlor...)
Affinity DataIC50: 6nMAssay Description:Inhibitory concentration against human prostaglandin E2 synthase (mPGES-1)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin E synthase 2(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50168761(3-(1-(4-chlorobenzyl)-5-(2-fluorobiphenyl-4-yl)-3-...)
Affinity DataIC50: 7nMAssay Description:Inhibitory concentration against human prostaglandin E2 synthase (mPGES-1)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin E synthase 2(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50168770(3-(1-(4-chlorobenzyl)-5-(2,2'-difluorobiphenyl-4-y...)
Affinity DataIC50: 8nMAssay Description:Inhibitory concentration against human prostaglandin E2 synthase (mPGES-1)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin E synthase 2(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50168782(3-[1-(4-Chloro-benzyl)-5-(3-fluoro-4-pyridin-3-yl-...)
Affinity DataIC50: 12nMAssay Description:Inhibitory concentration against human prostaglandin E2 synthase (mPGES-1)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin E synthase 2(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50168768(3-(5-(biphenyl-4-yl)-1-(4-chlorobenzyl)-3-methyl-1...)
Affinity DataIC50: 16nMAssay Description:Inhibitory concentration against human prostaglandin E2 synthase (mPGES-1)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin E synthase 2(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM181966(US9145380, 169)
Affinity DataIC50: 22nMpH: 6.8Assay Description:A solution of test compound was added to a diluted microsome preparation containing human mPGES-1 and pre-incubated for 15 minutes in potassium phosp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetProstaglandin E synthase 2(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50168787(3-(1-(4-chlorobenzyl)-5-(2-chlorobiphenyl-4-yl)-3-...)
Affinity DataIC50: 22nMAssay Description:Inhibitory concentration against human prostaglandin E2 synthase (mPGES-1)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin E synthase 2(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM182037(US9145380, 240)
Affinity DataIC50: 31nMpH: 6.8Assay Description:A solution of test compound was added to a diluted microsome preparation containing human mPGES-1 and pre-incubated for 15 minutes in potassium phosp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetProstaglandin E synthase 2(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50168788(3-[1-(4-Chloro-benzyl)-5-(2-fluoro-4'-methyl-biphe...)
Affinity DataIC50: 31nMAssay Description:Inhibitory concentration against human prostaglandin E2 synthase (mPGES-1)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin E synthase 2(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50168777(3-[1-(4-Chloro-benzyl)-5-(3-fluoro-4-pyrazin-2-yl-...)
Affinity DataIC50: 32nMAssay Description:Inhibitory concentration against human prostaglandin E2 synthase (mPGES-1)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin E synthase 2(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50168763(3-[1-(4-Chloro-benzyl)-5-(2-fluoro-3'-methyl-biphe...)
Affinity DataIC50: 33nMAssay Description:Inhibitory concentration against human prostaglandin E2 synthase (mPGES-1)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin E synthase 2(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM181846(US9145380, 49)
Affinity DataIC50: 36nMpH: 6.8Assay Description:A solution of test compound was added to a diluted microsome preparation containing human mPGES-1 and pre-incubated for 15 minutes in potassium phosp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetProstaglandin E synthase 2(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM181802(US9145380, 5)
Affinity DataIC50: 40nMpH: 6.8Assay Description:A solution of test compound was added to a diluted microsome preparation containing human mPGES-1 and pre-incubated for 15 minutes in potassium phosp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetProstaglandin E synthase 2(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM182009(US9145380, 212)
Affinity DataIC50: 41nMpH: 6.8Assay Description:A solution of test compound was added to a diluted microsome preparation containing human mPGES-1 and pre-incubated for 15 minutes in potassium phosp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetProstaglandin E synthase 2(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM181815(US9145380, 18)
Affinity DataIC50: 44nMpH: 6.8Assay Description:A solution of test compound was added to a diluted microsome preparation containing human mPGES-1 and pre-incubated for 15 minutes in potassium phosp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetProstaglandin E synthase 2(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM182005(US9145380, 208)
Affinity DataIC50: 55nMpH: 6.8Assay Description:A solution of test compound was added to a diluted microsome preparation containing human mPGES-1 and pre-incubated for 15 minutes in potassium phosp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetProstaglandin E synthase 2(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM181833(US9145380, 36)
Affinity DataIC50: 57nMpH: 6.8Assay Description:A solution of test compound was added to a diluted microsome preparation containing human mPGES-1 and pre-incubated for 15 minutes in potassium phosp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetProstaglandin E synthase 2(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM181803(US9145380, 6)
Affinity DataIC50: 74nMpH: 6.8Assay Description:A solution of test compound was added to a diluted microsome preparation containing human mPGES-1 and pre-incubated for 15 minutes in potassium phosp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetProstaglandin E synthase 2(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM181903(US9145380, 106)
Affinity DataIC50: 74nMpH: 6.8Assay Description:A solution of test compound was added to a diluted microsome preparation containing human mPGES-1 and pre-incubated for 15 minutes in potassium phosp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetProstaglandin E synthase 2(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM182008(US9145380, 211)
Affinity DataIC50: 75nMpH: 6.8Assay Description:A solution of test compound was added to a diluted microsome preparation containing human mPGES-1 and pre-incubated for 15 minutes in potassium phosp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetProstaglandin E synthase 2(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM181822(US9145380, 25)
Affinity DataIC50: 77nMpH: 6.8Assay Description:A solution of test compound was added to a diluted microsome preparation containing human mPGES-1 and pre-incubated for 15 minutes in potassium phosp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetProstaglandin E synthase 2(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM181801(US9145380, 4)
Affinity DataIC50: 79nMpH: 6.8Assay Description:A solution of test compound was added to a diluted microsome preparation containing human mPGES-1 and pre-incubated for 15 minutes in potassium phosp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetProstaglandin E synthase 2(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM181980(US9145380, 183)
Affinity DataIC50: 81nMpH: 6.8Assay Description:A solution of test compound was added to a diluted microsome preparation containing human mPGES-1 and pre-incubated for 15 minutes in potassium phosp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetProstaglandin E synthase 2(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM181849(US9145380, 52)
Affinity DataIC50: 84nMpH: 6.8Assay Description:A solution of test compound was added to a diluted microsome preparation containing human mPGES-1 and pre-incubated for 15 minutes in potassium phosp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetProstaglandin E synthase 2(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM181889(US9145380, 92)
Affinity DataIC50: 91nMpH: 6.8Assay Description:A solution of test compound was added to a diluted microsome preparation containing human mPGES-1 and pre-incubated for 15 minutes in potassium phosp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetProstaglandin E synthase 2(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM182004(US9145380, 207)
Affinity DataIC50: 97nMpH: 6.8Assay Description:A solution of test compound was added to a diluted microsome preparation containing human mPGES-1 and pre-incubated for 15 minutes in potassium phosp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetProstaglandin E synthase 2(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM182021(US9145380, 224)
Affinity DataIC50: 100nMpH: 6.8Assay Description:A solution of test compound was added to a diluted microsome preparation containing human mPGES-1 and pre-incubated for 15 minutes in potassium phosp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetProstaglandin E synthase 2(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM181840(US9145380, 43)
Affinity DataIC50: 110nMpH: 6.8Assay Description:A solution of test compound was added to a diluted microsome preparation containing human mPGES-1 and pre-incubated for 15 minutes in potassium phosp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetProstaglandin E synthase 2(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM182014(US9145380, 217)
Affinity DataIC50: 110nMpH: 6.8Assay Description:A solution of test compound was added to a diluted microsome preparation containing human mPGES-1 and pre-incubated for 15 minutes in potassium phosp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetProstaglandin E synthase 2(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM181831(US9145380, 34)
Affinity DataIC50: 120nMpH: 6.8Assay Description:A solution of test compound was added to a diluted microsome preparation containing human mPGES-1 and pre-incubated for 15 minutes in potassium phosp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetProstaglandin E synthase 2(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM181798(US9145380, 1)
Affinity DataIC50: 130nMpH: 6.8Assay Description:A solution of test compound was added to a diluted microsome preparation containing human mPGES-1 and pre-incubated for 15 minutes in potassium phosp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetProstaglandin E synthase 2(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM181847(US9145380, 50)
Affinity DataIC50: 130nMpH: 6.8Assay Description:A solution of test compound was added to a diluted microsome preparation containing human mPGES-1 and pre-incubated for 15 minutes in potassium phosp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetProstaglandin E synthase 2(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM182013(US9145380, 216)
Affinity DataIC50: 130nMpH: 6.8Assay Description:A solution of test compound was added to a diluted microsome preparation containing human mPGES-1 and pre-incubated for 15 minutes in potassium phosp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetProstaglandin E synthase 2(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM182025(US9145380, 228)
Affinity DataIC50: 130nMpH: 6.8Assay Description:A solution of test compound was added to a diluted microsome preparation containing human mPGES-1 and pre-incubated for 15 minutes in potassium phosp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetProstaglandin E synthase 2(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM182028(US9145380, 231)
Affinity DataIC50: 130nMpH: 6.8Assay Description:A solution of test compound was added to a diluted microsome preparation containing human mPGES-1 and pre-incubated for 15 minutes in potassium phosp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetProstaglandin E synthase 2(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM181800(US9145380, 3)
Affinity DataIC50: 140nMpH: 6.8Assay Description:A solution of test compound was added to a diluted microsome preparation containing human mPGES-1 and pre-incubated for 15 minutes in potassium phosp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetProstaglandin E synthase 2(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM181904(US9145380, 107)
Affinity DataIC50: 140nMpH: 6.8Assay Description:A solution of test compound was added to a diluted microsome preparation containing human mPGES-1 and pre-incubated for 15 minutes in potassium phosp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetProstaglandin E synthase 2(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM182030(US9145380, 233)
Affinity DataIC50: 150nMpH: 6.8Assay Description:A solution of test compound was added to a diluted microsome preparation containing human mPGES-1 and pre-incubated for 15 minutes in potassium phosp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetProstaglandin E synthase 2(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM181834(US9145380, 37)
Affinity DataIC50: 160nMpH: 6.8Assay Description:A solution of test compound was added to a diluted microsome preparation containing human mPGES-1 and pre-incubated for 15 minutes in potassium phosp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetProstaglandin E synthase 2(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM181850(US9145380, 53)
Affinity DataIC50: 160nMpH: 6.8Assay Description:A solution of test compound was added to a diluted microsome preparation containing human mPGES-1 and pre-incubated for 15 minutes in potassium phosp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetProstaglandin E synthase 2(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50168762(3-[5-Biphenyl-3-yl-1-(4-chloro-benzyl)-3-methyl-1H...)
Affinity DataIC50: 160nMAssay Description:Inhibitory concentration against human prostaglandin E2 synthase (mPGES-1)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin E synthase 2(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM181832(US9145380, 35)
Affinity DataIC50: 170nMpH: 6.8Assay Description:A solution of test compound was added to a diluted microsome preparation containing human mPGES-1 and pre-incubated for 15 minutes in potassium phosp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetProstaglandin E synthase 2(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM182015(US9145380, 218)
Affinity DataIC50: 180nMpH: 6.8Assay Description:A solution of test compound was added to a diluted microsome preparation containing human mPGES-1 and pre-incubated for 15 minutes in potassium phosp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetProstaglandin E synthase 2(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM181813(US9145380, 16)
Affinity DataIC50: 190nMpH: 6.8Assay Description:A solution of test compound was added to a diluted microsome preparation containing human mPGES-1 and pre-incubated for 15 minutes in potassium phosp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetProstaglandin E synthase 2(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM181881(US9145380, 84)
Affinity DataIC50: 190nMpH: 6.8Assay Description:A solution of test compound was added to a diluted microsome preparation containing human mPGES-1 and pre-incubated for 15 minutes in potassium phosp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetProstaglandin E synthase 2(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM181961(US9145380, 164)
Affinity DataIC50: 190nMpH: 6.8Assay Description:A solution of test compound was added to a diluted microsome preparation containing human mPGES-1 and pre-incubated for 15 minutes in potassium phosp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetProstaglandin E synthase 2(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM181835(US9145380, 38)
Affinity DataIC50: 220nMpH: 6.8Assay Description:A solution of test compound was added to a diluted microsome preparation containing human mPGES-1 and pre-incubated for 15 minutes in potassium phosp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

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