Compile Data Set for Download or QSAR
Report error Found 26 of ic50 data for polymerid = 7388,50000502
TargetSignal transducer and activator of transcription 5B(Human)
Leipzig University

Curated by ChEMBL
LigandPNGBDBM50267892(CHEMBL4088092)
Affinity DataIC50: 154nMAssay Description:Displacement of 5-carboxyfluorescein-GY(PO3H2)LVLDKW from STAT5B SH2 domain (unknown origin) pretreated for 1 hr followed by fluorescent tracer addit...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSignal transducer and activator of transcription 5B(Human)
Leipzig University

Curated by ChEMBL
LigandPNGBDBM50267888(CHEMBL4104462)
Affinity DataIC50: 220nMAssay Description:Displacement of 5-carboxyfluorescein-GY(PO3H2)LVLDKW from STAT5B SH2 domain (unknown origin) pretreated for 1 hr followed by fluorescent tracer addit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetSignal transducer and activator of transcription 5B(Human)
Leipzig University

Curated by ChEMBL
LigandPNGBDBM50267877(CHEMBL4103576)
Affinity DataIC50: 234nMAssay Description:Displacement of 5-carboxyfluorescein-GY(PO3H2)LVLDKW from STAT5B SH2 domain (unknown origin) pretreated for 1 hr followed by fluorescent tracer addit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetSignal transducer and activator of transcription 5B(Human)
Leipzig University

Curated by ChEMBL
LigandPNGBDBM50267890(CHEMBL4085646)
Affinity DataIC50: 240nMAssay Description:Displacement of 5-carboxyfluorescein-GY(PO3H2)LVLDKW from STAT5B SH2 domain (unknown origin) pretreated for 1 hr followed by fluorescent tracer addit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetSignal transducer and activator of transcription 5B(Human)
Leipzig University

Curated by ChEMBL
LigandPNGBDBM50267878(CHEMBL4104019)
Affinity DataIC50: 260nMAssay Description:Displacement of 5-carboxyfluorescein-GY(PO3H2)LVLDKW from STAT5B SH2 domain (unknown origin) pretreated for 1 hr followed by fluorescent tracer addit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetSignal transducer and activator of transcription 5B(Human)
Leipzig University

Curated by ChEMBL
LigandPNGBDBM50267889(CHEMBL4080219)
Affinity DataIC50: 270nMAssay Description:Displacement of 5-carboxyfluorescein-GY(PO3H2)LVLDKW from STAT5B SH2 domain (unknown origin) pretreated for 1 hr followed by fluorescent tracer addit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetSignal transducer and activator of transcription 5B(Human)
Leipzig University

Curated by ChEMBL
LigandPNGBDBM50267885(CHEMBL4066274)
Affinity DataIC50: 280nMAssay Description:Displacement of 5-carboxyfluorescein-GY(PO3H2)LVLDKW from STAT5B SH2 domain (unknown origin) pretreated for 1 hr followed by fluorescent tracer addit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetSignal transducer and activator of transcription 5B(Human)
Leipzig University

Curated by ChEMBL
LigandPNGBDBM50267884(CHEMBL4086096)
Affinity DataIC50: 290nMAssay Description:Displacement of 5-carboxyfluorescein-GY(PO3H2)LVLDKW from STAT5B SH2 domain (unknown origin) pretreated for 1 hr followed by fluorescent tracer addit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetSignal transducer and activator of transcription 5B(Human)
Leipzig University

Curated by ChEMBL
LigandPNGBDBM50267887(CHEMBL4077592)
Affinity DataIC50: 330nMAssay Description:Displacement of 5-carboxyfluorescein-GY(PO3H2)LVLDKW from STAT5B SH2 domain (unknown origin) pretreated for 1 hr followed by fluorescent tracer addit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetSignal transducer and activator of transcription 5B(Human)
Leipzig University

Curated by ChEMBL
LigandPNGBDBM50267886(CHEMBL4093849)
Affinity DataIC50: 350nMAssay Description:Displacement of 5-carboxyfluorescein-GY(PO3H2)LVLDKW from STAT5B SH2 domain (unknown origin) pretreated for 1 hr followed by fluorescent tracer addit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetSignal transducer and activator of transcription 5B(Human)
Leipzig University

Curated by ChEMBL
LigandPNGBDBM50267876(CHEMBL4080740)
Affinity DataIC50: 390nMAssay Description:Displacement of 5-carboxyfluorescein-GY(PO3H2)LVLDKW from STAT5B SH2 domain (unknown origin) pretreated for 1 hr followed by fluorescent tracer addit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetSignal transducer and activator of transcription 5B(Human)
Leipzig University

Curated by ChEMBL
LigandPNGBDBM50267862(CHEMBL4075745)
Affinity DataIC50: 460nMAssay Description:Displacement of 5-carboxyfluorescein-GY(PO3H2)LVLDKW from STAT5B SH2 domain (unknown origin) pretreated for 1 hr followed by fluorescent tracer addit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetSignal transducer and activator of transcription 5B(Human)
Leipzig University

Curated by ChEMBL
LigandPNGBDBM50267875(CHEMBL4062751)
Affinity DataIC50: 620nMAssay Description:Displacement of 5-carboxyfluorescein-GY(PO3H2)LVLDKW from STAT5B SH2 domain (unknown origin) pretreated for 1 hr followed by fluorescent tracer addit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetSignal transducer and activator of transcription 5B(Human)
Leipzig University

Curated by ChEMBL
LigandPNGBDBM50267891(CHEMBL4076474)
Affinity DataIC50: 660nMAssay Description:Displacement of 5-carboxyfluorescein-GY(PO3H2)LVLDKW from STAT5B SH2 domain (unknown origin) pretreated for 1 hr followed by fluorescent tracer addit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetSignal transducer and activator of transcription 5B(Human)
Leipzig University

Curated by ChEMBL
LigandPNGBDBM165192(4-((8-Methylnonanamido)methyl)-1,2-phenylene bis(d...)
Affinity DataKi:  340nM IC50: 750nMAssay Description:For competition-based fluorescence polarization assays, the ability of the test compounds to displace fluorophore-labeled peptides from their respect...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetSignal transducer and activator of transcription 5B(Human)
Leipzig University

Curated by ChEMBL
LigandPNGBDBM165193(4-(Nonanamidomethyl)-1,2-phenylene bis(dihydrogen ...)
Affinity DataKi:  390nM IC50: 860nMAssay Description:For competition-based fluorescence polarization assays, the ability of the test compounds to displace fluorophore-labeled peptides from their respect...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetSignal transducer and activator of transcription 5B(Human)
Leipzig University

Curated by ChEMBL
LigandPNGBDBM50514407(CHEMBL4483038)
Affinity DataIC50: 1.40E+3nMAssay Description:Binding affinity to MBP-tagged recombinant STAT5b-SH2 domain (unknown origin) using carboxyfluoresceine-labeled phosphotyrosine octapeptide incubated...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSignal transducer and activator of transcription 5B(Human)
Leipzig University

Curated by ChEMBL
LigandPNGBDBM50240455(CHEMBL1253351)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of 5-carboxyfluorescein-GpYLVLDKW-OH binding to STAT5B SH2 domain (unknown origin) pre-incubated for 1 hr before fluorescent-labelled pept...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSignal transducer and activator of transcription 5B(Human)
Leipzig University

Curated by ChEMBL
LigandPNGBDBM50514413(CHEMBL4555061)
Affinity DataIC50: 2.90E+3nMAssay Description:Binding affinity to MBP-tagged recombinant STAT5b-SH2 domain (unknown origin) using carboxyfluoresceine-labeled phosphotyrosine octapeptide incubated...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetSignal transducer and activator of transcription 5B(Human)
Leipzig University

Curated by ChEMBL
LigandPNGBDBM50000029(suramin | SURAMIN HEXASODIUM | CHEMBL265502 | 4-Me...)
Affinity DataIC50: 1.04E+4nMAssay Description:Inhibition of 5-carboxyfluorescein-GpYLVLDKW-OH binding to STAT5B SH2 domain (unknown origin) pre-incubated for 1 hr before fluorescent-labelled pept...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSignal transducer and activator of transcription 5B(Human)
Leipzig University

Curated by ChEMBL
LigandPNGBDBM50118228(5,7-Disulfo-4-(3-{3-[3-(4,6,8-trisulfo-naphthalen-...)
Affinity DataIC50: 1.27E+4nMAssay Description:Inhibition of 5-carboxyfluorescein-GpYLVLDKW-OH binding to STAT5B SH2 domain (unknown origin) pre-incubated for 1 hr before fluorescent-labelled pept...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50514414(CHEMBL4439829)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of STAT5b in mouse BaF3/FLT3-ITD cells assessed as reduction in cell proliferationMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetSignal transducer and activator of transcription 5B(Human)
Leipzig University

Curated by ChEMBL
LigandPNGBDBM50514414(CHEMBL4439829)
Affinity DataIC50: 3.70E+4nMAssay Description:Binding affinity to MBP-tagged recombinant STAT5b-SH2 domain (unknown origin) using carboxyfluoresceine-labeled phosphotyrosine octapeptide incubated...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
LigandPNGBDBM50514413(CHEMBL4555061)
Affinity DataIC50: 7.60E+4nMAssay Description:Inhibition of STAT5b in mouse BaF3/FLT3-ITD cells assessed as reduction in cell proliferationMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
LigandPNGBDBM50514407(CHEMBL4483038)
Affinity DataIC50: 1.53E+5nMAssay Description:Inhibition of STAT5b in mouse BaF3/FLT3-ITD cells assessed as reduction in cell proliferationMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSignal transducer and activator of transcription 5B(Human)
Leipzig University

Curated by ChEMBL
LigandPNGBDBM165191(2-Methoxy-4-(nonanamidomethyl)phenyl dihydrogen ph...)
Affinity DataKi:  9.60E+4nM IC50: 1.96E+5nMAssay Description:For competition-based fluorescence polarization assays, the ability of the test compounds to displace fluorophore-labeled peptides from their respect...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed