Compile Data Set for Download or QSAR
Report error Found 30 of ic50 data for polymerid = 7387
TargetSignal transducer and activator of transcription 5A(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50308060(CEP-701 | 16-hydroxy-16-(hydroxymethyl)-15-methyl-...)
Affinity DataIC50: 10nMAssay Description:Inhibition of STAT5 phosphorylation in HEL 92.1.7 cells incubated for 24 hrs by Western blot analysisMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetSignal transducer and activator of transcription 5A(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50335201(5-Chloro-N2-[(1S)-1-(5-fluoropyrimidin-2-yl)ethyl]...)
Affinity DataIC50: 25nMAssay Description:Inhibition of Stat5 phosphorylation in human SET2 cells after 1 hr by Western blottingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSignal transducer and activator of transcription 5A(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM569234(US11427563, Compound 169 | US11427563, Compound 27...)
Affinity DataIC50: 41nMAssay Description:All compounds were initially prepared as 10 mM stocks in anhydrous dimethylsulfoxide (DMSO). A 20 μl aliquot of the 10 mM solutions was transfer...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetSignal transducer and activator of transcription 5A(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50335201(5-Chloro-N2-[(1S)-1-(5-fluoropyrimidin-2-yl)ethyl]...)
Affinity DataIC50: 41nMAssay Description:Inhibition of Stat5 phosphorylation in human HEL cells after 1 hr by Western blottingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSignal transducer and activator of transcription 5A(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM569237(US11427563, Compound 28 | US11427563, Compound 104)
Affinity DataIC50: 57nMAssay Description:All compounds were initially prepared as 10 mM stocks in anhydrous dimethylsulfoxide (DMSO). A 20 μl aliquot of the 10 mM solutions was transfer...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetSignal transducer and activator of transcription 5A(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM569273(US11427563, Compound 157 | US11427563, Compound 99...)
Affinity DataIC50: 200nMAssay Description:All compounds were initially prepared as 10 mM stocks in anhydrous dimethylsulfoxide (DMSO). A 20 μl aliquot of the 10 mM solutions was transfer...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetSignal transducer and activator of transcription 5A(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50295809(12,13-(2,3-Cis-dihyroxy-1,4-butyl)-6,7,12,13-tetra...)
Affinity DataIC50: 689nMAssay Description:Inhibition of STAT5 phosphorylation in IL2-stimulated healthy human T cells by Western blottingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSignal transducer and activator of transcription 5A(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM569235(US11427563, Compound 10 | US11427563, Compound 143...)
Affinity DataIC50: 1.00E+3nMAssay Description:All compounds were initially prepared as 10 mM stocks in anhydrous dimethylsulfoxide (DMSO). A 20 μl aliquot of the 10 mM solutions was transfer...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetSignal transducer and activator of transcription 5A(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50240455(CHEMBL1253351)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of 5-carboxyfluorescein-GpYLVLDKW-OH binding to C-terminal 6x-His-tagged and an N-terminal maltose-binding protein-tagged STAT5A SH2 domai...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSignal transducer and activator of transcription 5A(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50267892(CHEMBL4088092)
Affinity DataIC50: 4.97E+3nMAssay Description:Displacement of 5-carboxyfluorescein-GY(PO3H2)LVLDKW from C-terminal His6-tagged/N-terminal maltose-binding protein-tagged STAT5A SH2 domain (unknown...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSignal transducer and activator of transcription 5A(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50267888(CHEMBL4104462)
Affinity DataIC50: 7.20E+3nMAssay Description:Displacement of 5-carboxyfluorescein-GY(PO3H2)LVLDKW from STAT5A SH2 domain (unknown origin) pretreated for 1 hr followed by fluorescent tracer addit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetSignal transducer and activator of transcription 5A(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50267878(CHEMBL4104019)
Affinity DataIC50: 7.30E+3nMAssay Description:Displacement of 5-carboxyfluorescein-GY(PO3H2)LVLDKW from STAT5A SH2 domain (unknown origin) pretreated for 1 hr followed by fluorescent tracer addit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetSignal transducer and activator of transcription 5A(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50267887(CHEMBL4077592)
Affinity DataIC50: 7.40E+3nMAssay Description:Displacement of 5-carboxyfluorescein-GY(PO3H2)LVLDKW from STAT5A SH2 domain (unknown origin) pretreated for 1 hr followed by fluorescent tracer addit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetSignal transducer and activator of transcription 5A(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50267890(CHEMBL4085646)
Affinity DataIC50: 7.60E+3nMAssay Description:Displacement of 5-carboxyfluorescein-GY(PO3H2)LVLDKW from STAT5A SH2 domain (unknown origin) pretreated for 1 hr followed by fluorescent tracer addit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetSignal transducer and activator of transcription 5A(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50267886(CHEMBL4093849)
Affinity DataIC50: 8.30E+3nMAssay Description:Displacement of 5-carboxyfluorescein-GY(PO3H2)LVLDKW from STAT5A SH2 domain (unknown origin) pretreated for 1 hr followed by fluorescent tracer addit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetSignal transducer and activator of transcription 5A(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50267877(CHEMBL4103576)
Affinity DataIC50: 8.40E+3nMAssay Description:Displacement of 5-carboxyfluorescein-GY(PO3H2)LVLDKW from STAT5A SH2 domain (unknown origin) pretreated for 1 hr followed by fluorescent tracer addit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetSignal transducer and activator of transcription 5A(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50267876(CHEMBL4080740)
Affinity DataIC50: 8.60E+3nMAssay Description:Displacement of 5-carboxyfluorescein-GY(PO3H2)LVLDKW from STAT5A SH2 domain (unknown origin) pretreated for 1 hr followed by fluorescent tracer addit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetSignal transducer and activator of transcription 5A(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50118228(5,7-Disulfo-4-(3-{3-[3-(4,6,8-trisulfo-naphthalen-...)
Affinity DataIC50: 8.80E+3nMAssay Description:Inhibition of 5-carboxyfluorescein-GpYLVLDKW-OH binding to C-terminal 6x-His-tagged and an N-terminal maltose-binding protein-tagged STAT5A SH2 domai...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSignal transducer and activator of transcription 5A(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50267889(CHEMBL4080219)
Affinity DataIC50: 8.90E+3nMAssay Description:Displacement of 5-carboxyfluorescein-GY(PO3H2)LVLDKW from STAT5A SH2 domain (unknown origin) pretreated for 1 hr followed by fluorescent tracer addit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetSignal transducer and activator of transcription 5A(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50267862(CHEMBL4075745)
Affinity DataIC50: 9.10E+3nMAssay Description:Displacement of 5-carboxyfluorescein-GY(PO3H2)LVLDKW from STAT5A SH2 domain (unknown origin) pretreated for 1 hr followed by fluorescent tracer addit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetSignal transducer and activator of transcription 5A(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50000029(suramin | SURAMIN HEXASODIUM | CHEMBL265502 | 4-Me...)
Affinity DataIC50: 9.40E+3nMAssay Description:Inhibition of 5-carboxyfluorescein-GpYLVLDKW-OH binding to C-terminal 6x-His-tagged and an N-terminal maltose-binding protein-tagged STAT5A SH2 domai...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSignal transducer and activator of transcription 5A(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50267885(CHEMBL4066274)
Affinity DataIC50: 9.70E+3nMAssay Description:Displacement of 5-carboxyfluorescein-GY(PO3H2)LVLDKW from STAT5A SH2 domain (unknown origin) pretreated for 1 hr followed by fluorescent tracer addit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetSignal transducer and activator of transcription 5A(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50267891(CHEMBL4076474)
Affinity DataIC50: 1.05E+4nMAssay Description:Displacement of 5-carboxyfluorescein-GY(PO3H2)LVLDKW from STAT5A SH2 domain (unknown origin) pretreated for 1 hr followed by fluorescent tracer addit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetSignal transducer and activator of transcription 5A(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50267884(CHEMBL4086096)
Affinity DataIC50: 1.06E+4nMAssay Description:Displacement of 5-carboxyfluorescein-GY(PO3H2)LVLDKW from STAT5A SH2 domain (unknown origin) pretreated for 1 hr followed by fluorescent tracer addit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetSignal transducer and activator of transcription 5A(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50267875(CHEMBL4062751)
Affinity DataIC50: 1.19E+4nMAssay Description:Displacement of 5-carboxyfluorescein-GY(PO3H2)LVLDKW from STAT5A SH2 domain (unknown origin) pretreated for 1 hr followed by fluorescent tracer addit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetSignal transducer and activator of transcription 5A(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM165193(4-(Nonanamidomethyl)-1,2-phenylene bis(dihydrogen ...)
Affinity DataKi:  1.23E+4nM IC50: 2.49E+4nMAssay Description:For competition-based fluorescence polarization assays, the ability of the test compounds to displace fluorophore-labeled peptides from their respect...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetSignal transducer and activator of transcription 5A(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM165192(4-((8-Methylnonanamido)methyl)-1,2-phenylene bis(d...)
Affinity DataKi:  1.30E+4nM IC50: 2.64E+4nMAssay Description:For competition-based fluorescence polarization assays, the ability of the test compounds to displace fluorophore-labeled peptides from their respect...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetSignal transducer and activator of transcription 5A(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50408834(CHEMBL5271424)
Affinity DataIC50: 5.08E+4nMAssay Description:Inhibition of STAT5a (unknown origin)More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetSignal transducer and activator of transcription 5A(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM165191(2-Methoxy-4-(nonanamidomethyl)phenyl dihydrogen ph...)
Affinity DataKi:  4.90E+4nM IC50: 9.80E+4nMAssay Description:For competition-based fluorescence polarization assays, the ability of the test compounds to displace fluorophore-labeled peptides from their respect...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetSignal transducer and activator of transcription 5A(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM165190(2-Methoxy-4-((8-methylnonanamido)methyl)phenyl dih...)
Affinity DataKi:  7.50E+4nM IC50: 1.52E+5nMAssay Description:For competition-based fluorescence polarization assays, the ability of the test compounds to displace fluorophore-labeled peptides from their respect...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed