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Report error Found 31 of ic50 data for polymerid = 693

Protein polybromo-1 [645-766](Human)
Genentech

US Patent

BDBM394585(US10308614, Example 188 | 2-(6-amino-5-(1-(1-)

IC50: 2.5nMAssay Description:Histidine-Flag-PB1-BD5 Bromodomain645-766 (S645-D766; Swiss Prot Q86U86; mhhhhhhasdykddddkgslvprgsSGISPKKSKYMTPMQQKLNEVYEAVKNYTDKRGRRLSAI FLRLPSRSELP...More data for this Ligand-Target Pair

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Protein polybromo-1 [645-766](Human)
Genentech

US Patent

BDBM394584(US10308614, Example 187 | 2-(6-amino-5-(1-methyl-)

IC50: 3.70nMAssay Description:Histidine-Flag-PB1-BD5 Bromodomain645-766 (S645-D766; Swiss Prot Q86U86; mhhhhhhasdykddddkgslvprgsSGISPKKSKYMTPMQQKLNEVYEAVKNYTDKRGRRLSAI FLRLPSRSELP...More data for this Ligand-Target Pair

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Protein polybromo-1 [645-766](Human)
Genentech

US Patent

BDBM394605(US10308614, Example 209 | 2-(6-amino-5-cyclohexylp...)

IC50: 5.20nMAssay Description:Histidine-Flag-PB1-BD5 Bromodomain645-766 (S645-D766; Swiss Prot Q86U86; mhhhhhhasdykddddkgslvprgsSGISPKKSKYMTPMQQKLNEVYEAVKNYTDKRGRRLSAI FLRLPSRSELP...More data for this Ligand-Target Pair

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Protein polybromo-1 [645-766](Human)
Genentech

US Patent

BDBM394575(US10308614, Example 178 | 2-(6-amino-5-(2-)

IC50: 5.30nMAssay Description:Histidine-Flag-PB1-BD5 Bromodomain645-766 (S645-D766; Swiss Prot Q86U86; mhhhhhhasdykddddkgslvprgsSGISPKKSKYMTPMQQKLNEVYEAVKNYTDKRGRRLSAI FLRLPSRSELP...More data for this Ligand-Target Pair

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Protein polybromo-1 [645-766](Human)
Genentech

US Patent

BDBM394528(US10308614, Example 129 | 1-(4-(3-amino-6-(2-)

IC50: 6.80nMAssay Description:Histidine-Flag-PB1-BD5 Bromodomain645-766 (S645-D766; Swiss Prot Q86U86; mhhhhhhasdykddddkgslvprgsSGISPKKSKYMTPMQQKLNEVYEAVKNYTDKRGRRLSAI FLRLPSRSELP...More data for this Ligand-Target Pair

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Protein polybromo-1 [645-766](Human)
Genentech

US Patent

BDBM394571(US10308614, Example 174 | 2-(6-amino-5-)

IC50: 8.80nMAssay Description:Histidine-Flag-PB1-BD5 Bromodomain645-766 (S645-D766; Swiss Prot Q86U86; mhhhhhhasdykddddkgslvprgsSGISPKKSKYMTPMQQKLNEVYEAVKNYTDKRGRRLSAI FLRLPSRSELP...More data for this Ligand-Target Pair

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Protein polybromo-1 [645-766](Human)
Genentech

US Patent

BDBM394583(US10308614, Example 186 | 2-(6-amino-5-phenylpyrid...)

IC50: 8.90nMAssay Description:Histidine-Flag-PB1-BD5 Bromodomain645-766 (S645-D766; Swiss Prot Q86U86; mhhhhhhasdykddddkgslvprgsSGISPKKSKYMTPMQQKLNEVYEAVKNYTDKRGRRLSAI FLRLPSRSELP...More data for this Ligand-Target Pair

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Protein polybromo-1 [645-766](Human)
Genentech

US Patent

BDBM394567(US10308614, Example 170 | (S)-2-(6-amino-5-(1-)

IC50: 9.60nMAssay Description:Histidine-Flag-PB1-BD5 Bromodomain645-766 (S645-D766; Swiss Prot Q86U86; mhhhhhhasdykddddkgslvprgsSGISPKKSKYMTPMQQKLNEVYEAVKNYTDKRGRRLSAI FLRLPSRSELP...More data for this Ligand-Target Pair

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Protein polybromo-1 [645-766](Human)
Genentech

US Patent

BDBM394456(US10308614, Example 57 | 2-(6-amino-5-(3-)

IC50: 13.3nMAssay Description:Histidine-Flag-PB1-BD5 Bromodomain645-766 (S645-D766; Swiss Prot Q86U86; mhhhhhhasdykddddkgslvprgsSGISPKKSKYMTPMQQKLNEVYEAVKNYTDKRGRRLSAI FLRLPSRSELP...More data for this Ligand-Target Pair

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Protein polybromo-1 [645-766](Human)
Genentech

US Patent

BDBM394490(US10308614, Example 90 | 2-(6-amino-5-(piperidin-1...)

IC50: 13.9nMAssay Description:Histidine-Flag-PB1-BD5 Bromodomain645-766 (S645-D766; Swiss Prot Q86U86; mhhhhhhasdykddddkgslvprgsSGISPKKSKYMTPMQQKLNEVYEAVKNYTDKRGRRLSAI FLRLPSRSELP...More data for this Ligand-Target Pair

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Protein polybromo-1 [645-766](Human)
Genentech

US Patent

BDBM394606(US10308614, Example 210 | 2-(6-amino-5-)

IC50: 14.9nMAssay Description:Histidine-Flag-PB1-BD5 Bromodomain645-766 (S645-D766; Swiss Prot Q86U86; mhhhhhhasdykddddkgslvprgsSGISPKKSKYMTPMQQKLNEVYEAVKNYTDKRGRRLSAI FLRLPSRSELP...More data for this Ligand-Target Pair

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Protein polybromo-1 [645-766](Human)
Genentech

US Patent

BDBM394507(US10308614, Example 108 | 2-(6-amino-5-(3-methyl-4...)

IC50: 15.9nMAssay Description:Histidine-Flag-PB1-BD5 Bromodomain645-766 (S645-D766; Swiss Prot Q86U86; mhhhhhhasdykddddkgslvprgsSGISPKKSKYMTPMQQKLNEVYEAVKNYTDKRGRRLSAI FLRLPSRSELP...More data for this Ligand-Target Pair

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Protein polybromo-1 [645-766](Human)
Genentech

US Patent

BDBM394521(US10308614, Example 122 | 1-(4-(3-amino-6-(2-hydro...)

IC50: 16.3nMAssay Description:Histidine-Flag-PB1-BD5 Bromodomain645-766 (S645-D766; Swiss Prot Q86U86; mhhhhhhasdykddddkgslvprgsSGISPKKSKYMTPMQQKLNEVYEAVKNYTDKRGRRLSAI FLRLPSRSELP...More data for this Ligand-Target Pair

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Protein polybromo-1 [645-766](Human)
Genentech

US Patent

BDBM394403(US10308614, Example 5 | 2-(6-amino-5-(4-((dimethyl...)

IC50: 16.4nMAssay Description:Histidine-Flag-PB1-BD5 Bromodomain645-766 (S645-D766; Swiss Prot Q86U86; mhhhhhhasdykddddkgslvprgsSGISPKKSKYMTPMQQKLNEVYEAVKNYTDKRGRRLSAI FLRLPSRSELP...More data for this Ligand-Target Pair

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US Patent

Protein polybromo-1 [645-766](Human)
Genentech

US Patent

BDBM394408(US10308614, Example 9 | 2-(6-amino-5-((3aR,6aS)-5-)

IC50: 18.2nMAssay Description:Histidine-Flag-PB1-BD5 Bromodomain645-766 (S645-D766; Swiss Prot Q86U86; mhhhhhhasdykddddkgslvprgsSGISPKKSKYMTPMQQKLNEVYEAVKNYTDKRGRRLSAI FLRLPSRSELP...More data for this Ligand-Target Pair

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Protein polybromo-1 [645-766](Human)
Genentech

US Patent

BDBM394444(US10308614, Example 45 | 2-(6-amino-5-)

IC50: 20.9nMAssay Description:Histidine-Flag-PB1-BD5 Bromodomain645-766 (S645-D766; Swiss Prot Q86U86; mhhhhhhasdykddddkgslvprgsSGISPKKSKYMTPMQQKLNEVYEAVKNYTDKRGRRLSAI FLRLPSRSELP...More data for this Ligand-Target Pair

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Protein polybromo-1 [645-766](Human)
Genentech

US Patent

BDBM394518(US10308614, Example 119 | 2-(6-amino-5-(3-benzyl-)

IC50: 23.3nMAssay Description:Histidine-Flag-PB1-BD5 Bromodomain645-766 (S645-D766; Swiss Prot Q86U86; mhhhhhhasdykddddkgslvprgsSGISPKKSKYMTPMQQKLNEVYEAVKNYTDKRGRRLSAI FLRLPSRSELP...More data for this Ligand-Target Pair

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Protein polybromo-1 [645-766](Human)
Genentech

US Patent

BDBM394432(US10308614, Example 33 | 2-(6-amino-5-(2,6-)

IC50: 24nMAssay Description:Histidine-Flag-PB1-BD5 Bromodomain645-766 (S645-D766; Swiss Prot Q86U86; mhhhhhhasdykddddkgslvprgsSGISPKKSKYMTPMQQKLNEVYEAVKNYTDKRGRRLSAI FLRLPSRSELP...More data for this Ligand-Target Pair

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Protein polybromo-1 [645-766](Human)
Genentech

US Patent

BDBM394414(US10308614, Example 15 | 2-(6-amino-5-(4-(1-)

IC50: 24.5nMAssay Description:Histidine-Flag-PB1-BD5 Bromodomain645-766 (S645-D766; Swiss Prot Q86U86; mhhhhhhasdykddddkgslvprgsSGISPKKSKYMTPMQQKLNEVYEAVKNYTDKRGRRLSAI FLRLPSRSELP...More data for this Ligand-Target Pair

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UniProtKB/SwissProt
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Protein polybromo-1 [645-766](Human)
Genentech

US Patent

BDBM394402(US10308614, Example 4 | 1-(4-(3-amino-6-(2-)

IC50: 24.6nMAssay Description:Histidine-Flag-PB1-BD5 Bromodomain645-766 (S645-D766; Swiss Prot Q86U86; mhhhhhhasdykddddkgslvprgsSGISPKKSKYMTPMQQKLNEVYEAVKNYTDKRGRRLSAI FLRLPSRSELP...More data for this Ligand-Target Pair

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Protein polybromo-1 [645-766](Human)
Genentech

US Patent

BDBM394401(US10308614, Example 3 | 2-(6-amino-5-(4-(pyridin-)

IC50: 25.2nMAssay Description:Histidine-Flag-PB1-BD5 Bromodomain645-766 (S645-D766; Swiss Prot Q86U86; mhhhhhhasdykddddkgslvprgsSGISPKKSKYMTPMQQKLNEVYEAVKNYTDKRGRRLSAI FLRLPSRSELP...More data for this Ligand-Target Pair

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UniProtKB/SwissProt
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Protein polybromo-1 [645-766](Human)
Genentech

US Patent

BDBM394586(US10308614, Example 189 | 2-(6-amino-5-(4-)

IC50: 28.8nMAssay Description:Histidine-Flag-PB1-BD5 Bromodomain645-766 (S645-D766; Swiss Prot Q86U86; mhhhhhhasdykddddkgslvprgsSGISPKKSKYMTPMQQKLNEVYEAVKNYTDKRGRRLSAI FLRLPSRSELP...More data for this Ligand-Target Pair

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UniProtKB/SwissProt
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Protein polybromo-1 [645-766](Human)
Genentech

US Patent

BDBM394574(US10308614, Example 177 | 2-(6-amino-5-((1-)

IC50: 29.2nMAssay Description:Histidine-Flag-PB1-BD5 Bromodomain645-766 (S645-D766; Swiss Prot Q86U86; mhhhhhhasdykddddkgslvprgsSGISPKKSKYMTPMQQKLNEVYEAVKNYTDKRGRRLSAI FLRLPSRSELP...More data for this Ligand-Target Pair

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UniProtKB/SwissProt
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Protein polybromo-1 [645-766](Human)
Genentech

US Patent

BDBM394602(US10308614, Example 206 | 2-(6-amino-5-phenylpyrid...)

IC50: 29.5nMAssay Description:Histidine-Flag-PB1-BD5 Bromodomain645-766 (S645-D766; Swiss Prot Q86U86; mhhhhhhasdykddddkgslvprgsSGISPKKSKYMTPMQQKLNEVYEAVKNYTDKRGRRLSAI FLRLPSRSELP...More data for this Ligand-Target Pair

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UniProtKB/SwissProt
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US Patent

Protein polybromo-1 [645-766](Human)
Genentech

US Patent

BDBM394577(US10308614, Example 180 | 2-(6-amino-5-((1-)

IC50: 43.9nMAssay Description:Histidine-Flag-PB1-BD5 Bromodomain645-766 (S645-D766; Swiss Prot Q86U86; mhhhhhhasdykddddkgslvprgsSGISPKKSKYMTPMQQKLNEVYEAVKNYTDKRGRRLSAI FLRLPSRSELP...More data for this Ligand-Target Pair

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UniProtKB/SwissProt
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Protein polybromo-1 [645-766](Human)
Genentech

US Patent

BDBM394614(US10308614, Example 218 | 2-(6-amino-5-(1-benzylpi...)

IC50: 44.8nMAssay Description:Histidine-Flag-PB1-BD5 Bromodomain645-766 (S645-D766; Swiss Prot Q86U86; mhhhhhhasdykddddkgslvprgsSGISPKKSKYMTPMQQKLNEVYEAVKNYTDKRGRRLSAI FLRLPSRSELP...More data for this Ligand-Target Pair

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UniProtKB/SwissProt
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Protein polybromo-1 [645-766](Human)
Genentech

US Patent

BDBM394415(US10308614, Example 16 | 2-(6-amino-5-(8-benzyl-3,...)

IC50: 51.3nMAssay Description:Histidine-Flag-PB1-BD5 Bromodomain645-766 (S645-D766; Swiss Prot Q86U86; mhhhhhhasdykddddkgslvprgsSGISPKKSKYMTPMQQKLNEVYEAVKNYTDKRGRRLSAI FLRLPSRSELP...More data for this Ligand-Target Pair

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UniProtKB/SwissProt
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Protein polybromo-1 [645-766](Human)
Genentech

US Patent

BDBM394565(US10308614, Example 168 | 2-(6-amino-5-(1-)

IC50: 113nMAssay Description:Histidine-Flag-PB1-BD5 Bromodomain645-766 (S645-D766; Swiss Prot Q86U86; mhhhhhhasdykddddkgslvprgsSGISPKKSKYMTPMQQKLNEVYEAVKNYTDKRGRRLSAI FLRLPSRSELP...More data for this Ligand-Target Pair

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Protein polybromo-1 [645-766](Human)
Genentech

US Patent

BDBM394570(US10308614, Example 173 | 2-(6-amino-5-(2-)

IC50: 257nMAssay Description:Histidine-Flag-PB1-BD5 Bromodomain645-766 (S645-D766; Swiss Prot Q86U86; mhhhhhhasdykddddkgslvprgsSGISPKKSKYMTPMQQKLNEVYEAVKNYTDKRGRRLSAI FLRLPSRSELP...More data for this Ligand-Target Pair

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Protein polybromo-1 [645-766](Human)
Genentech

US Patent

BDBM394613(US10308614, Example 217 | 2-(6-amino-5-(1-(phenyls...)

IC50: 268nMAssay Description:Histidine-Flag-PB1-BD5 Bromodomain645-766 (S645-D766; Swiss Prot Q86U86; mhhhhhhasdykddddkgslvprgsSGISPKKSKYMTPMQQKLNEVYEAVKNYTDKRGRRLSAI FLRLPSRSELP...More data for this Ligand-Target Pair

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Protein polybromo-1 [645-766](Human)
Genentech

US Patent

BDBM394600(US10308614, Example 204 | 2-(6-(methylamino)pyrida...)

IC50: 349nMAssay Description:Histidine-Flag-PB1-BD5 Bromodomain645-766 (S645-D766; Swiss Prot Q86U86; mhhhhhhasdykddddkgslvprgsSGISPKKSKYMTPMQQKLNEVYEAVKNYTDKRGRRLSAI FLRLPSRSELP...More data for this Ligand-Target Pair

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