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Report error Found 44 of ic50 data for polymerid = 6643,50007732
LigandPNGBDBM2579(CHEMBL388978 | Staurosporine, 8 | Staurosporin, 4 ...)
Affinity DataIC50: 0.387nMAssay Description:Inhibition of human CAMK2G using KKLNRTLSFAEPG as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM2579(CHEMBL388978 | Staurosporine, 8 | Staurosporin, 4 ...)
Affinity DataIC50: 0.656nMAssay Description:Inhibition of human CAMK2G using KKLNRTLSFAEPG as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM139540(US8889696, Staurosporine | US9051313, Staurosporin...)
Affinity DataIC50: 0.700nMAssay Description:The compound of Example 39, 2-(1H-indol-5-ylamino)-6-(2,4-difluorophenylsulfonyl)-8-methylpyrido[2,3-d]pyrimidin-7(8H)-one, was subjected to a kinase...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

LigandPNGBDBM50520464(CHEMBL4556306)
Affinity DataIC50: 0.790nMAssay Description:Inhibition of CamK-II (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
LigandPNGBDBM458847(US10759792, Compound I-14 | US11325908, Compound I...)
Affinity DataIC50: 100nMAssay Description:The inhibition of CaMKII activity was evaluated using a coupled assay measuring ADP released following ATP hydrolysis and phosphor-transfer to the pe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

LigandPNGBDBM458846(US10759792, Compound I-13 | US11325908, Compound I...)
Affinity DataIC50: 100nMAssay Description:The inhibition of CaMKII activity was evaluated using a coupled assay measuring ADP released following ATP hydrolysis and phosphor-transfer to the pe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

LigandPNGBDBM458844(US10759792, Compound I-12 | US11325908, Compound I...)
Affinity DataIC50: 100nMAssay Description:The inhibition of CaMKII activity was evaluated using a coupled assay measuring ADP released following ATP hydrolysis and phosphor-transfer to the pe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

LigandPNGBDBM458823(US10759792, Compound 9j | US11325908, Compound 9j)
Affinity DataIC50: 100nMAssay Description:The inhibition of CaMKII activity was evaluated using a coupled assay measuring ADP released following ATP hydrolysis and phosphor-transfer to the pe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

LigandPNGBDBM458842(US10759792, Compound I-11 | US11325908, Compound I...)
Affinity DataIC50: 100nMAssay Description:The inhibition of CaMKII activity was evaluated using a coupled assay measuring ADP released following ATP hydrolysis and phosphor-transfer to the pe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

LigandPNGBDBM458840(US10759792, Compound I-10 | US11325908, Compound I...)
Affinity DataIC50: 100nMAssay Description:The inhibition of CaMKII activity was evaluated using a coupled assay measuring ADP released following ATP hydrolysis and phosphor-transfer to the pe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

LigandPNGBDBM458837(US10759792, Compound I-9 | US11325908, Compound I-...)
Affinity DataIC50: 100nMAssay Description:The inhibition of CaMKII activity was evaluated using a coupled assay measuring ADP released following ATP hydrolysis and phosphor-transfer to the pe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

LigandPNGBDBM458833(US10759792, Compound I-7 | US11325908, Compound I-...)
Affinity DataIC50: 100nMAssay Description:The inhibition of CaMKII activity was evaluated using a coupled assay measuring ADP released following ATP hydrolysis and phosphor-transfer to the pe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

LigandPNGBDBM458835(US10759792, Compound I-8 | US11325908, Compound I-...)
Affinity DataIC50: 100nMAssay Description:The inhibition of CaMKII activity was evaluated using a coupled assay measuring ADP released following ATP hydrolysis and phosphor-transfer to the pe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

LigandPNGBDBM4552(CHEMBL288441 | SKI-606 | 4-[(2,4-Dichloro-5-methox...)
Affinity DataIC50: 184nMAssay Description:Inhibition of CAMK2GMore data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
LigandPNGBDBM458822(US10759792, Compound I-4 | US11325908, Compound I-...)
Affinity DataIC50: 550nMAssay Description:The inhibition of CaMKII activity was evaluated using a coupled assay measuring ADP released following ATP hydrolysis and phosphor-transfer to the pe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

LigandPNGBDBM458831(US10759792, Compound I-6 | US11325908, Compound I-...)
Affinity DataIC50: 550nMAssay Description:The inhibition of CaMKII activity was evaluated using a coupled assay measuring ADP released following ATP hydrolysis and phosphor-transfer to the pe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

LigandPNGBDBM458796(US10759792, Compound I-1 | US11325908, Compound I-...)
Affinity DataIC50: 550nMAssay Description:The inhibition of CaMKII activity was evaluated using a coupled assay measuring ADP released following ATP hydrolysis and phosphor-transfer to the pe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

LigandPNGBDBM50520464(CHEMBL4556306)
Affinity DataIC50: 790nMAssay Description:Inhibition of CAMK-II (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
LigandPNGBDBM50563780(CHEMBL4795714)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of wild-type human CAMK2gamma using KKLNRTLSFAEPG peptide as substrate in presence of Ca2+ calmodulin and [gamma-33P]-ATP by radiometric h...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
LigandPNGBDBM458836(US10759792, Compound 9n | US11325908, Compound 9n)
Affinity DataIC50: 5.50E+3nMAssay Description:The inhibition of CaMKII activity was evaluated using a coupled assay measuring ADP released following ATP hydrolysis and phosphor-transfer to the pe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

LigandPNGBDBM458799(US10759792, Compound 9a | US11325908, Compound 9a)
Affinity DataIC50: 5.50E+3nMAssay Description:The inhibition of CaMKII activity was evaluated using a coupled assay measuring ADP released following ATP hydrolysis and phosphor-transfer to the pe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

LigandPNGBDBM458843(US10759792, Compound 8q | US11325908, Compound 8q)
Affinity DataIC50: 5.50E+3nMAssay Description:The inhibition of CaMKII activity was evaluated using a coupled assay measuring ADP released following ATP hydrolysis and phosphor-transfer to the pe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

LigandPNGBDBM458829(US10759792, Compound I-5 | US11325908, Compound I-...)
Affinity DataIC50: 5.50E+3nMAssay Description:The inhibition of CaMKII activity was evaluated using a coupled assay measuring ADP released following ATP hydrolysis and phosphor-transfer to the pe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

LigandPNGBDBM50252338(CHEMBL4090364)
Affinity DataIC50: 9.20E+3nMAssay Description:Inhibition of CaMK2gamma (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM139539(US8889696, 39)
Affinity DataIC50: 1.00E+4nMAssay Description:The compound of Example 39, 2-(1H-indol-5-ylamino)-6-(2,4-difluorophenylsulfonyl)-8-methylpyrido[2,3-d]pyrimidin-7(8H)-one, was subjected to a kinase...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

LigandPNGBDBM50519662(CHEMBL4438748)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant human CaMK2gamma (1 to 330 residues) using calmodulin as substrate incubated for 40 mins in presence of [gamma-33ATP] by ra...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50401152(CHEMBL2205766)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CAMK2GMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50499634(CHEMBL3741589)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CaMK2gamma (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50135286(CHEMBL3745885)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human CAMK2gamma using [KKLNRTLSFAEPG] as substrateMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM458834(US10759792, Compound 9m | US11325908, Compound 9m)
Affinity DataIC50: 5.50E+4nMAssay Description:The inhibition of CaMKII activity was evaluated using a coupled assay measuring ADP released following ATP hydrolysis and phosphor-transfer to the pe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

LigandPNGBDBM458810(US10759792, Compound 9e | US11325908, Compound 9e)
Affinity DataIC50: 5.50E+4nMAssay Description:The inhibition of CaMKII activity was evaluated using a coupled assay measuring ADP released following ATP hydrolysis and phosphor-transfer to the pe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

LigandPNGBDBM458804(US10759792, Compound I-2 | US11325908, Compound I-...)
Affinity DataIC50: 5.50E+4nMAssay Description:The inhibition of CaMKII activity was evaluated using a coupled assay measuring ADP released following ATP hydrolysis and phosphor-transfer to the pe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

LigandPNGBDBM458838(US10759792, Compound 9o | US11325908, Compound 9o)
Affinity DataIC50: 5.50E+4nMAssay Description:The inhibition of CaMKII activity was evaluated using a coupled assay measuring ADP released following ATP hydrolysis and phosphor-transfer to the pe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

LigandPNGBDBM458830(US10759792, Compound 9k | US11325908, Compound 9k)
Affinity DataIC50: 5.50E+4nMAssay Description:The inhibition of CaMKII activity was evaluated using a coupled assay measuring ADP released following ATP hydrolysis and phosphor-transfer to the pe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

LigandPNGBDBM553989(US11325908, Compound 8p)
Affinity DataIC50: 5.50E+4nMAssay Description:The inhibition of CaMKII activity was evaluated using a coupled assay measuring ADP released following ATP hydrolysis and phosphor-transfer to the pe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

LigandPNGBDBM458811(US10759792, Compound I-3 | US11325908, Compound I-...)
Affinity DataIC50: 5.50E+4nMAssay Description:The inhibition of CaMKII activity was evaluated using a coupled assay measuring ADP released following ATP hydrolysis and phosphor-transfer to the pe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

LigandPNGBDBM458832(US10759792, Compound 9l | US11325908, Compound 9l)
Affinity DataIC50: 5.50E+4nMAssay Description:The inhibition of CaMKII activity was evaluated using a coupled assay measuring ADP released following ATP hydrolysis and phosphor-transfer to the pe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

LigandPNGBDBM458845(US10759792, Compound 8r | US11325908, Compound 8r)
Affinity DataIC50: 5.50E+4nMAssay Description:The inhibition of CaMKII activity was evaluated using a coupled assay measuring ADP released following ATP hydrolysis and phosphor-transfer to the pe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

LigandPNGBDBM458812(US10759792, Compound 9h | US11325908, Compound 9h)
Affinity DataIC50: 5.50E+4nMAssay Description:The inhibition of CaMKII activity was evaluated using a coupled assay measuring ADP released following ATP hydrolysis and phosphor-transfer to the pe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

LigandPNGBDBM50469777(CHEMBL115531)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of Calcium/calmodulin-dependent protein kinase type IIMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
LigandPNGBDBM50469778(CHEMBL116963)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of Calcium/calmodulin-dependent protein kinase type IIMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
LigandPNGBDBM50074289(CHEMBL536932 | CHEMBL278819 | (4-Methyl-6-phenyl-p...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of Calcium/calmodulin-dependent protein kinase type IIMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50469776(CHEMBL117443)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of Calcium/calmodulin-dependent protein kinase type IIMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
LigandPNGBDBM50043341(CHEMBL3355059)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of CAMK2gamma (unknown origin) by Millipore kinase analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed