Compile Data Set for Download or QSAR
Report error Found 78 of ic50 data for polymerid = 556
TargetFascin(Human)
Cruk Beatson Institute

Curated by ChEMBL
LigandPNGBDBM50526225(CHEMBL4452711)
Affinity DataIC50: 240nMAssay Description:Inhibition of human (His8)2-tagged fascin (1 to 493 residues) expressed in Escherichia coli BL21(DE3) pLysS assessed as reduction in F-actin bundling...More data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetFascin(Human)
Cruk Beatson Institute

Curated by ChEMBL
LigandPNGBDBM50526241(CHEMBL4461540)
Affinity DataIC50: 330nMAssay Description:Inhibition of human (His8)2-tagged fascin (1 to 493 residues) expressed in Escherichia coli BL21(DE3) pLysS assessed as reduction in F-actin bundling...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetFascin(Human)
Cruk Beatson Institute

Curated by ChEMBL
LigandPNGBDBM350103((Z)-N-(2,3-diphenyl-1,2,4- thiadiazol-5(2H)- ylide...)
Affinity DataIC50: 500nMAssay Description:A high throughput assay was developed to screen for fascin specific inhibitors. Purified polymerized F-actin with or without fascin were mixed and in...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetFascin(Human)
Cruk Beatson Institute

Curated by ChEMBL
LigandPNGBDBM350103((Z)-N-(2,3-diphenyl-1,2,4- thiadiazol-5(2H)- ylide...)
Affinity DataIC50: 500nMAssay Description:About 150,000 compounds were screened. These chemical compounds were from the LOPAC 1280 collection, the Prestwick chemical library, the Pharmakon co...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetFascin(Human)
Cruk Beatson Institute

Curated by ChEMBL
LigandPNGBDBM350103((Z)-N-(2,3-diphenyl-1,2,4- thiadiazol-5(2H)- ylide...)
Affinity DataIC50: 500nMAssay Description:About 150,000 compounds were screened. These chemical compounds were from the LOPAC 1280 collection, the Prestwick chemical library, the Pharmakon co...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetFascin(Human)
Cruk Beatson Institute

Curated by ChEMBL
LigandPNGBDBM350103((Z)-N-(2,3-diphenyl-1,2,4- thiadiazol-5(2H)- ylide...)
Affinity DataIC50: 500nMAssay Description:A high throughput assay was developed to screen for fascin specific inhibitors. Purified polymerized F-actin with or without fascin were mixed and in...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetFascin(Human)
Cruk Beatson Institute

Curated by ChEMBL
LigandPNGBDBM50526227(CHEMBL4574198)
Affinity DataIC50: 510nMAssay Description:Inhibition of human (His8)2-tagged fascin (1 to 493 residues) expressed in Escherichia coli BL21(DE3) pLysS assessed as reduction in F-actin bundling...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetFascin(Human)
Cruk Beatson Institute

Curated by ChEMBL
LigandPNGBDBM350111(US10208043, # 12 | N-(3-(1H-1,2,4-triazol-3- ylthi...)
Affinity DataIC50: 539nMAssay Description:A high throughput assay was developed to screen for fascin specific inhibitors. Purified polymerized F-actin with or without fascin were mixed and in...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetFascin(Human)
Cruk Beatson Institute

Curated by ChEMBL
LigandPNGBDBM350111(US10208043, # 12 | N-(3-(1H-1,2,4-triazol-3- ylthi...)
Affinity DataIC50: 539nMAssay Description:About 150,000 compounds were screened. These chemical compounds were from the LOPAC 1280 collection, the Prestwick chemical library, the Pharmakon co...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetFascin(Human)
Cruk Beatson Institute

Curated by ChEMBL
LigandPNGBDBM50526240(CHEMBL4566108)
Affinity DataIC50: 630nMAssay Description:Inhibition of human (His8)2-tagged fascin (1 to 493 residues) expressed in Escherichia coli BL21(DE3) pLysS assessed as reduction in F-actin bundling...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetFascin(Human)
Cruk Beatson Institute

Curated by ChEMBL
LigandPNGBDBM50526226(CHEMBL4559691)
Affinity DataIC50: 630nMAssay Description:Inhibition of human (His8)2-tagged fascin (1 to 493 residues) expressed in Escherichia coli BL21(DE3) pLysS assessed as reduction in F-actin bundling...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetFascin(Human)
Cruk Beatson Institute

Curated by ChEMBL
LigandPNGBDBM350102(US10208043, # 3 | 2-chloro-N-(6- chlorobenzo[d]thi...)
Affinity DataIC50: 652nMAssay Description:A high throughput assay was developed to screen for fascin specific inhibitors. Purified polymerized F-actin with or without fascin were mixed and in...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetFascin(Human)
Cruk Beatson Institute

Curated by ChEMBL
LigandPNGBDBM350102(US10208043, # 3 | 2-chloro-N-(6- chlorobenzo[d]thi...)
Affinity DataIC50: 652nMAssay Description:About 150,000 compounds were screened. These chemical compounds were from the LOPAC 1280 collection, the Prestwick chemical library, the Pharmakon co...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetFascin(Human)
Cruk Beatson Institute

Curated by ChEMBL
LigandPNGBDBM350107(US10208043, # 8 | N-(3-(1H-1,2,4-triazol-3- ylthio...)
Affinity DataIC50: 683nMAssay Description:About 150,000 compounds were screened. These chemical compounds were from the LOPAC 1280 collection, the Prestwick chemical library, the Pharmakon co...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetFascin(Human)
Cruk Beatson Institute

Curated by ChEMBL
LigandPNGBDBM350107(US10208043, # 8 | N-(3-(1H-1,2,4-triazol-3- ylthio...)
Affinity DataIC50: 683nMAssay Description:A high throughput assay was developed to screen for fascin specific inhibitors. Purified polymerized F-actin with or without fascin were mixed and in...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetFascin(Human)
Cruk Beatson Institute

Curated by ChEMBL
LigandPNGBDBM350100(US10208043, # 1 | 5-(3,4-dichlorobenzyl)-1- (S,S,-...)
Affinity DataIC50: 734nMAssay Description:A high throughput assay was developed to screen for fascin specific inhibitors. Purified polymerized F-actin with or without fascin were mixed and in...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetFascin(Human)
Cruk Beatson Institute

Curated by ChEMBL
LigandPNGBDBM350100(US10208043, # 1 | 5-(3,4-dichlorobenzyl)-1- (S,S,-...)
Affinity DataIC50: 734nMAssay Description:About 150,000 compounds were screened. These chemical compounds were from the LOPAC 1280 collection, the Prestwick chemical library, the Pharmakon co...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetFascin(Human)
Cruk Beatson Institute

Curated by ChEMBL
LigandPNGBDBM350109(US10208043, # 10 | N-(3-(1H-1,2,4-triazol-3- ylthi...)
Affinity DataIC50: 807nMAssay Description:About 150,000 compounds were screened. These chemical compounds were from the LOPAC 1280 collection, the Prestwick chemical library, the Pharmakon co...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetFascin(Human)
Cruk Beatson Institute

Curated by ChEMBL
LigandPNGBDBM350109(US10208043, # 10 | N-(3-(1H-1,2,4-triazol-3- ylthi...)
Affinity DataIC50: 807nMAssay Description:A high throughput assay was developed to screen for fascin specific inhibitors. Purified polymerized F-actin with or without fascin were mixed and in...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetFascin(Human)
Cruk Beatson Institute

Curated by ChEMBL
LigandPNGBDBM350110(US10208043, # 11 | N-(3-(1H-1,2,4-triazol-3- ylthi...)
Affinity DataIC50: 890nMAssay Description:About 150,000 compounds were screened. These chemical compounds were from the LOPAC 1280 collection, the Prestwick chemical library, the Pharmakon co...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetFascin(Human)
Cruk Beatson Institute

Curated by ChEMBL
LigandPNGBDBM350110(US10208043, # 11 | N-(3-(1H-1,2,4-triazol-3- ylthi...)
Affinity DataIC50: 890nMAssay Description:A high throughput assay was developed to screen for fascin specific inhibitors. Purified polymerized F-actin with or without fascin were mixed and in...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetFascin(Human)
Cruk Beatson Institute

Curated by ChEMBL
LigandPNGBDBM350120(US10208043, # 21 | 5-(3-chlorobenzyl)-1-(2- hydrox...)
Affinity DataIC50: 1.20E+3nMAssay Description:A high throughput assay was developed to screen for fascin specific inhibitors. Purified polymerized F-actin with or without fascin were mixed and in...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetFascin(Human)
Cruk Beatson Institute

Curated by ChEMBL
LigandPNGBDBM350120(US10208043, # 21 | 5-(3-chlorobenzyl)-1-(2- hydrox...)
Affinity DataIC50: 1.20E+3nMAssay Description:About 150,000 compounds were screened. These chemical compounds were from the LOPAC 1280 collection, the Prestwick chemical library, the Pharmakon co...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetFascin(Human)
Cruk Beatson Institute

Curated by ChEMBL
LigandPNGBDBM50526224(CHEMBL4451624)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of human (His8)2-tagged fascin (1 to 493 residues) expressed in Escherichia coli BL21(DE3) pLysS assessed as reduction in F-actin bundling...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetFascin(Human)
Cruk Beatson Institute

Curated by ChEMBL
LigandPNGBDBM350108(US10208043, # 9 | N-(3-(1H-1,2,4-triazol-3- ylthio...)
Affinity DataIC50: 1.47E+3nMAssay Description:About 150,000 compounds were screened. These chemical compounds were from the LOPAC 1280 collection, the Prestwick chemical library, the Pharmakon co...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetFascin(Human)
Cruk Beatson Institute

Curated by ChEMBL
LigandPNGBDBM350108(US10208043, # 9 | N-(3-(1H-1,2,4-triazol-3- ylthio...)
Affinity DataIC50: 1.47E+3nMAssay Description:A high throughput assay was developed to screen for fascin specific inhibitors. Purified polymerized F-actin with or without fascin were mixed and in...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetFascin(Human)
Cruk Beatson Institute

Curated by ChEMBL
LigandPNGBDBM350101(US10208043, # 2 | N-(1-(4- (trifluoromethyl)benzyl...)
Affinity DataIC50: 2.00E+3nMAssay Description:A high throughput assay was developed to screen for fascin specific inhibitors. Purified polymerized F-actin with or without fascin were mixed and in...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetFascin(Human)
Cruk Beatson Institute

Curated by ChEMBL
LigandPNGBDBM350101(US10208043, # 2 | N-(1-(4- (trifluoromethyl)benzyl...)
Affinity DataIC50: 2.00E+3nMAssay Description:About 150,000 compounds were screened. These chemical compounds were from the LOPAC 1280 collection, the Prestwick chemical library, the Pharmakon co...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetFascin(Human)
Cruk Beatson Institute

Curated by ChEMBL
LigandPNGBDBM350128(US10208043, # 30 | 5-(3,4-dichlorobenzyl)-1- o-tol...)
Affinity DataIC50: 2.00E+3nMAssay Description:About 150,000 compounds were screened. These chemical compounds were from the LOPAC 1280 collection, the Prestwick chemical library, the Pharmakon co...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetFascin(Human)
Cruk Beatson Institute

Curated by ChEMBL
LigandPNGBDBM350106(N-phenyl-2,3-diphenyl- 1,2,4-thiadiazolium-5- amin...)
Affinity DataIC50: 2.00E+3nMAssay Description:A high throughput assay was developed to screen for fascin specific inhibitors. Purified polymerized F-actin with or without fascin were mixed and in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetFascin(Human)
Cruk Beatson Institute

Curated by ChEMBL
LigandPNGBDBM350118(US10208043, # 19 | N-(6- chlorobenzo[d]thiazol-2- ...)
Affinity DataIC50: 2.00E+3nMAssay Description:About 150,000 compounds were screened. These chemical compounds were from the LOPAC 1280 collection, the Prestwick chemical library, the Pharmakon co...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetFascin(Human)
Cruk Beatson Institute

Curated by ChEMBL
LigandPNGBDBM350112(US10208043, # 13 | (Z)-N-(3-(1H-1,2,4-triazol- 3-y...)
Affinity DataIC50: 2.00E+3nMAssay Description:A high throughput assay was developed to screen for fascin specific inhibitors. Purified polymerized F-actin with or without fascin were mixed and in...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetFascin(Human)
Cruk Beatson Institute

Curated by ChEMBL
LigandPNGBDBM350118(US10208043, # 19 | N-(6- chlorobenzo[d]thiazol-2- ...)
Affinity DataIC50: 2.00E+3nMAssay Description:A high throughput assay was developed to screen for fascin specific inhibitors. Purified polymerized F-actin with or without fascin were mixed and in...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetFascin(Human)
Cruk Beatson Institute

Curated by ChEMBL
LigandPNGBDBM350128(US10208043, # 30 | 5-(3,4-dichlorobenzyl)-1- o-tol...)
Affinity DataIC50: 2.00E+3nMAssay Description:A high throughput assay was developed to screen for fascin specific inhibitors. Purified polymerized F-actin with or without fascin were mixed and in...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetFascin(Human)
Cruk Beatson Institute

Curated by ChEMBL
LigandPNGBDBM350112(US10208043, # 13 | (Z)-N-(3-(1H-1,2,4-triazol- 3-y...)
Affinity DataIC50: 2.00E+3nMAssay Description:About 150,000 compounds were screened. These chemical compounds were from the LOPAC 1280 collection, the Prestwick chemical library, the Pharmakon co...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetFascin(Human)
Cruk Beatson Institute

Curated by ChEMBL
LigandPNGBDBM350106(N-phenyl-2,3-diphenyl- 1,2,4-thiadiazolium-5- amin...)
Affinity DataIC50: 2.00E+3nMAssay Description:About 150,000 compounds were screened. These chemical compounds were from the LOPAC 1280 collection, the Prestwick chemical library, the Pharmakon co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetFascin(Human)
Cruk Beatson Institute

Curated by ChEMBL
LigandPNGBDBM350130(US10208043, # 32 | 5-(3,4-dichlorobenzyl)-1- (2,4-...)
Affinity DataIC50: 2.10E+3nMAssay Description:A high throughput assay was developed to screen for fascin specific inhibitors. Purified polymerized F-actin with or without fascin were mixed and in...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetFascin(Human)
Cruk Beatson Institute

Curated by ChEMBL
LigandPNGBDBM50526230(CHEMBL4457641)
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of human (His8)2-tagged fascin (1 to 493 residues) expressed in Escherichia coli BL21(DE3) pLysS assessed as reduction in F-actin bundling...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetFascin(Human)
Cruk Beatson Institute

Curated by ChEMBL
LigandPNGBDBM350130(US10208043, # 32 | 5-(3,4-dichlorobenzyl)-1- (2,4-...)
Affinity DataIC50: 2.10E+3nMAssay Description:About 150,000 compounds were screened. These chemical compounds were from the LOPAC 1280 collection, the Prestwick chemical library, the Pharmakon co...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetFascin(Human)
Cruk Beatson Institute

Curated by ChEMBL
LigandPNGBDBM350129(US10208043, # 31 | 5-(3,4-dichlorobenzyl)-1- (2,3-...)
Affinity DataIC50: 2.30E+3nMAssay Description:A high throughput assay was developed to screen for fascin specific inhibitors. Purified polymerized F-actin with or without fascin were mixed and in...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetFascin(Human)
Cruk Beatson Institute

Curated by ChEMBL
LigandPNGBDBM350129(US10208043, # 31 | 5-(3,4-dichlorobenzyl)-1- (2,3-...)
Affinity DataIC50: 2.30E+3nMAssay Description:About 150,000 compounds were screened. These chemical compounds were from the LOPAC 1280 collection, the Prestwick chemical library, the Pharmakon co...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetFascin(Human)
Cruk Beatson Institute

Curated by ChEMBL
LigandPNGBDBM50076451(CHEMBL3235887 | US10208043, # 14 | US10941146, # 1...)
Affinity DataIC50: 2.62E+3nMAssay Description:A high throughput assay was developed to screen for fascin specific inhibitors. Purified polymerized F-actin with or without fascin were mixed and in...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetFascin(Human)
Cruk Beatson Institute

Curated by ChEMBL
LigandPNGBDBM50076451(CHEMBL3235887 | US10208043, # 14 | US10941146, # 1...)
Affinity DataIC50: 2.62E+3nMAssay Description:About 150,000 compounds were screened. These chemical compounds were from the LOPAC 1280 collection, the Prestwick chemical library, the Pharmakon co...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetFascin(Human)
Cruk Beatson Institute

Curated by ChEMBL
LigandPNGBDBM350114(US10208043, # 15 | N-(3-(1H-1,2,4-triazol-3- ylthi...)
Affinity DataIC50: 2.70E+3nMAssay Description:About 150,000 compounds were screened. These chemical compounds were from the LOPAC 1280 collection, the Prestwick chemical library, the Pharmakon co...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetFascin(Human)
Cruk Beatson Institute

Curated by ChEMBL
LigandPNGBDBM350114(US10208043, # 15 | N-(3-(1H-1,2,4-triazol-3- ylthi...)
Affinity DataIC50: 2.70E+3nMAssay Description:A high throughput assay was developed to screen for fascin specific inhibitors. Purified polymerized F-actin with or without fascin were mixed and in...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetFascin(Human)
Cruk Beatson Institute

Curated by ChEMBL
LigandPNGBDBM350121(US10208043, # 23 | 2-(4-oxo-1-(S,S,-dioxo- tetrahy...)
Affinity DataIC50: 3.40E+3nMAssay Description:A high throughput assay was developed to screen for fascin specific inhibitors. Purified polymerized F-actin with or without fascin were mixed and in...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetFascin(Human)
Cruk Beatson Institute

Curated by ChEMBL
LigandPNGBDBM350121(US10208043, # 23 | 2-(4-oxo-1-(S,S,-dioxo- tetrahy...)
Affinity DataIC50: 3.40E+3nMAssay Description:About 150,000 compounds were screened. These chemical compounds were from the LOPAC 1280 collection, the Prestwick chemical library, the Pharmakon co...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetFascin(Human)
Cruk Beatson Institute

Curated by ChEMBL
LigandPNGBDBM350127(US10208043, # 29 | 5-(2-(benzo[d][1,3]dioxol- 5-yl...)
Affinity DataIC50: 3.70E+3nMAssay Description:A high throughput assay was developed to screen for fascin specific inhibitors. Purified polymerized F-actin with or without fascin were mixed and in...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetFascin(Human)
Cruk Beatson Institute

Curated by ChEMBL
LigandPNGBDBM350127(US10208043, # 29 | 5-(2-(benzo[d][1,3]dioxol- 5-yl...)
Affinity DataIC50: 3.70E+3nMAssay Description:About 150,000 compounds were screened. These chemical compounds were from the LOPAC 1280 collection, the Prestwick chemical library, the Pharmakon co...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetFascin(Human)
Cruk Beatson Institute

Curated by ChEMBL
LigandPNGBDBM50526235(CHEMBL4516481)
Affinity DataIC50: 3.80E+3nMAssay Description:Inhibition of human (His8)2-tagged fascin (1 to 493 residues) expressed in Escherichia coli BL21(DE3) pLysS assessed as reduction in F-actin bundling...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
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