Compile Data Set for Download or QSAR
Report error Found 592 of ic50 data for polymerid = 5474,6712
TargetHormone-sensitive lipase(Human)
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50147315(2-(4-(3-fluorophenyl)piperidine-1-carbonyl)-4-(2-m...)
Affinity DataIC50: 0.200nMAssay Description:Inhibition of forskolin-stimulated lipolysis in differentiated 3T3-L1 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHormone-sensitive lipase(Rat)
University of Jordan

Curated by ChEMBL
LigandPNGBDBM50138750(3-(4-chlorophenyl)-N,N-dimethyl-5-(methylthio)-1H-...)
Affinity DataIC50: 0.353nMAssay Description:Inhibition of HSL in Wistar rat isolated fat cells by spectrophotometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHormone-sensitive lipase(Rat)
University of Jordan

Curated by ChEMBL
LigandPNGBDBM50138739(4-tert-butyl-N-(4-(5-methoxy-2-oxo-1,3,4-oxadiazol...)
Affinity DataIC50: 0.410nMAssay Description:Inhibition of HSL in Wistar rat isolated fat cells by spectrophotometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHormone-sensitive lipase(Rat)
University of Jordan

Curated by ChEMBL
LigandPNGBDBM50138743(N,N-dimethyl-5-(methylthio)-3-p-tolyl-1H-1,2,4-tri...)
Affinity DataIC50: 0.530nMAssay Description:Inhibition of HSL in Wistar rat isolated fat cells by spectrophotometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHormone-sensitive lipase(Human)
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50142719(Morpholin-4-yl-carbamic acid 4-[(4-tert-butyl-cycl...)
Affinity DataIC50: 1nMAssay Description:Inhibition of human recombinant hormone sensitive lipase.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHormone-sensitive lipase(Human)
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50147297(4-Isopropyl-2-[4-(3-methoxy-phenyl)-piperazine-1-c...)
Affinity DataIC50: 1nMAssay Description:Inhibition of human recombinant hormone sensitive lipase (HSL)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHormone-sensitive lipase(Rat)
University of Jordan

Curated by ChEMBL
LigandPNGBDBM50147299(4-butyl-3-methyl-2-(4-methylpiperidine-1-carbonyl)...)
Affinity DataIC50: 1nMAssay Description:Inhibition of HSL in Wistar rat isolated fat cells by spectrophotometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHormone-sensitive lipase(Human)
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50147299(4-butyl-3-methyl-2-(4-methylpiperidine-1-carbonyl)...)
Affinity DataIC50: 1nMAssay Description:Inhibition of human recombinant hormone sensitive lipase (HSL)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHormone-sensitive lipase(Rat)
University of Jordan

Curated by ChEMBL
LigandPNGBDBM50138742(3-(4-Chloro-phenyl)-5-propylsulfanyl-[1,2,4]triazo...)
Affinity DataIC50: 1.06nMAssay Description:Inhibition of HSL in Wistar rat isolated fat cells by spectrophotometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHormone-sensitive lipase(Rat)
University of Jordan

Curated by ChEMBL
LigandPNGBDBM50138758(3-(4-Chloro-phenyl)-5-cyclopropylmethylsulfanyl-[1...)
Affinity DataIC50: 1.09nMAssay Description:Inhibition of HSL in Wistar rat isolated fat cells by spectrophotometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHormone-sensitive lipase(Rat)
University of Jordan

Curated by ChEMBL
LigandPNGBDBM50138761(N-methyl-5-(methylthio)-N-phenyl-3-p-tolyl-1H-1,2,...)
Affinity DataIC50: 1.76nMAssay Description:Inhibition of HSL in Wistar rat isolated fat cells by spectrophotometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHormone-sensitive lipase(Rat)
University of Jordan

Curated by ChEMBL
LigandPNGBDBM50138745((3-(4-chlorophenyl)-5-(methylthio)-1H-1,2,4-triazo...)
Affinity DataIC50: 1.76nMAssay Description:Inhibition of HSL in Wistar rat isolated fat cells by spectrophotometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHormone-sensitive lipase(Rat)
University of Jordan

Curated by ChEMBL
LigandPNGBDBM50138733(5-Methylsulfanyl-3-(4-trifluoromethyl-phenyl)-[1,2...)
Affinity DataIC50: 1.76nMAssay Description:Inhibition of HSL in Wistar rat isolated fat cells by spectrophotometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHormone-sensitive lipase(Rat)
University of Jordan

Curated by ChEMBL
LigandPNGBDBM50138759(N,N-dimethyl-5-(methylthio)-3-(4-(trifluoromethoxy...)
Affinity DataIC50: 1.76nMAssay Description:Inhibition of HSL in Wistar rat isolated fat cells by spectrophotometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHormone-sensitive lipase(Human)
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50147270(3-methyl-4-(2-phenoxyethyl)-2-(piperidine-1-carbon...)
Affinity DataIC50: 2nMAssay Description:Inhibition of forskolin-stimulated lipolysis in differentiated 3T3-L1 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHormone-sensitive lipase(Human)
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50147251(4-Isopropyl-3-methyl-5-oxo-5H-isoxazole-2-carboxyl...)
Affinity DataIC50: 2nMAssay Description:Inhibition of human recombinant hormone sensitive lipase (HSL)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHormone-sensitive lipase(Rat)
University of Jordan

Curated by ChEMBL
LigandPNGBDBM50147251(4-Isopropyl-3-methyl-5-oxo-5H-isoxazole-2-carboxyl...)
Affinity DataIC50: 2nMAssay Description:Inhibition of HSL in Wistar rat isolated fat cells by spectrophotometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHormone-sensitive lipase(Rat)
University of Jordan

Curated by ChEMBL
LigandPNGBDBM50147243(4-Isopropyl-3-methyl-2-(piperidine-1-carbonyl)-2H-...)
Affinity DataIC50: 2nMAssay Description:Inhibition of HSL in Wistar rat isolated fat cells by spectrophotometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHormone-sensitive lipase(Human)
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50147243(4-Isopropyl-3-methyl-2-(piperidine-1-carbonyl)-2H-...)
Affinity DataIC50: 2nMAssay Description:Inhibition of human recombinant hormone sensitive lipase (HSL)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHormone-sensitive lipase(Human)
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50233398(CHEMBL4063082)
Affinity DataIC50: 2nMAssay Description:Inhibition of recombinant human HSL expressed in baculovirus infected sf9 cells using PNPB as substrate after 5 mins by spectrophotometric methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHormone-sensitive lipase(Human)
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50233398(CHEMBL4063082)
Affinity DataIC50: 2nMAssay Description:Inhibition of recombinant human HSL expressed in baculovirus infected sf9 insect cells using PNPB as substrate after 5 mins by spectrophotometric ana...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHormone-sensitive lipase(Human)
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM121019(US8722721, 11)
Affinity DataIC50: 2.40nMpH: 7.2 T: 2°CAssay Description:HSL enzyme activity was measured by a colorimetric assay using 2,3-dimercapto-1-propanol tributyrate (Aldrich, St. Louis, Mo.) as a substrate. Typica...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetHormone-sensitive lipase(Rat)
University of Jordan

Curated by ChEMBL
LigandPNGBDBM50138749(3-(4-chlorophenyl)-N-methyl-5-(methylthio)-N-pheny...)
Affinity DataIC50: 2.82nMAssay Description:Inhibition of HSL in Wistar rat isolated fat cells by spectrophotometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHormone-sensitive lipase(Human)
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50138735((S)-4-isopropyl-3-methyl-2-(3-methylpiperidine-1-c...)
Affinity DataIC50: 3nMAssay Description:Inhibition of human recombinant hormone sensitive lipase (HSL)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHormone-sensitive lipase(Human)
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50142713((3,4-Dihydro-1H-isoquinolin-2-yl)-carbamic acid 4-...)
Affinity DataIC50: 3nMAssay Description:Inhibition of human recombinant hormone sensitive lipase.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHormone-sensitive lipase(Rat)
University of Jordan

Curated by ChEMBL
LigandPNGBDBM50138737(3-(4-chlorophenyl)-N-methyl-N-phenyl-5-(2,2,2-trif...)
Affinity DataIC50: 3nMAssay Description:Inhibition of HSL in Wistar rat isolated fat cells by spectrophotometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHormone-sensitive lipase(Rat)
University of Jordan

Curated by ChEMBL
LigandPNGBDBM50147257(4-(2-ethoxyethyl)-3-methyl-2-(4-methylpiperidine-1...)
Affinity DataIC50: 3nMAssay Description:Inhibition of HSL in Wistar rat isolated fat cells by spectrophotometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHormone-sensitive lipase(Rat)
University of Jordan

Curated by ChEMBL
LigandPNGBDBM50147281(4-isobutyl-3-methyl-2-(4-methylpiperidine-1-carbon...)
Affinity DataIC50: 3nMAssay Description:Inhibition of HSL in Wistar rat isolated fat cells by spectrophotometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHormone-sensitive lipase(Rat)
University of Jordan

Curated by ChEMBL
LigandPNGBDBM50138735((S)-4-isopropyl-3-methyl-2-(3-methylpiperidine-1-c...)
Affinity DataIC50: 3nMAssay Description:Inhibition of HSL in Wistar rat isolated fat cells by spectrophotometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHormone-sensitive lipase(Human)
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50147281(4-isobutyl-3-methyl-2-(4-methylpiperidine-1-carbon...)
Affinity DataIC50: 3nMAssay Description:Inhibition of human recombinant hormone sensitive lipase (HSL)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHormone-sensitive lipase(Human)
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50147257(4-(2-ethoxyethyl)-3-methyl-2-(4-methylpiperidine-1...)
Affinity DataIC50: 3nMAssay Description:Inhibition of human recombinant hormone sensitive lipase (HSL)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHormone-sensitive lipase(Human)
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50147251(4-Isopropyl-3-methyl-5-oxo-5H-isoxazole-2-carboxyl...)
Affinity DataIC50: 3nMAssay Description:Inhibition of forskolin-stimulated lipolysis in differentiated 3T3-L1 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHormone-sensitive lipase(Rat)
University of Jordan

Curated by ChEMBL
LigandPNGBDBM50138747([3-(4-Chloro-phenyl)-5-cyclopropylmethylsulfanyl-[...)
Affinity DataIC50: 3.53nMAssay Description:Inhibition of HSL in Wistar rat isolated fat cells by spectrophotometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHormone-sensitive lipase(Human)
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM121018(US8722721, 10)
Affinity DataIC50: 3.70nMpH: 7.2 T: 2°CAssay Description:HSL enzyme activity was measured by a colorimetric assay using 2,3-dimercapto-1-propanol tributyrate (Aldrich, St. Louis, Mo.) as a substrate. Typica...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetHormone-sensitive lipase(Rat)
University of Jordan

Curated by ChEMBL
LigandPNGBDBM50138731(3-(4-chlorophenyl)-5-(ethylthio)-N,N-dimethyl-1H-1...)
Affinity DataIC50: 3.71nMAssay Description:Inhibition of HSL in Wistar rat isolated fat cells by spectrophotometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHormone-sensitive lipase(Human)
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50147253(2-[4-(3-Fluoro-phenyl)-piperidine-1-carbonyl]-4-is...)
Affinity DataIC50: 4nMAssay Description:Inhibition of forskolin-stimulated lipolysis in differentiated 3T3-L1 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHormone-sensitive lipase(Human)
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50147279(N-(2-fluorobenzyl)-4-isopropyl-N,3-dimethyl-5-oxoi...)
Affinity DataIC50: 4nMAssay Description:Inhibition of human recombinant hormone sensitive lipase (HSL)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHormone-sensitive lipase(Human)
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50147245(4-isobutyl-3-methyl-2-(4-phenylpiperidine-1-carbon...)
Affinity DataIC50: 4nMAssay Description:Inhibition of forskolin-stimulated lipolysis in differentiated 3T3-L1 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHormone-sensitive lipase(Rat)
University of Jordan

Curated by ChEMBL
LigandPNGBDBM50147241(4-Isopropyl-3-methyl-5-oxo-5H-isoxazole-2-carboxyl...)
Affinity DataIC50: 4nMAssay Description:Inhibition of HSL in Wistar rat isolated fat cells by spectrophotometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHormone-sensitive lipase(Rat)
University of Jordan

Curated by ChEMBL
LigandPNGBDBM50147279(N-(2-fluorobenzyl)-4-isopropyl-N,3-dimethyl-5-oxoi...)
Affinity DataIC50: 4nMAssay Description:Inhibition of HSL in Wistar rat isolated fat cells by spectrophotometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHormone-sensitive lipase(Rat)
University of Jordan

Curated by ChEMBL
LigandPNGBDBM50147270(3-methyl-4-(2-phenoxyethyl)-2-(piperidine-1-carbon...)
Affinity DataIC50: 4nMAssay Description:Inhibition of HSL in Wistar rat isolated fat cells by spectrophotometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHormone-sensitive lipase(Rat)
University of Jordan

Curated by ChEMBL
LigandPNGBDBM50147267(4-cyclohexyl-3-methyl-2-(4-methylpiperidine-1-carb...)
Affinity DataIC50: 4nMAssay Description:Inhibition of HSL in Wistar rat isolated fat cells by spectrophotometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHormone-sensitive lipase(Human)
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50147241(4-Isopropyl-3-methyl-5-oxo-5H-isoxazole-2-carboxyl...)
Affinity DataIC50: 4nMAssay Description:Inhibition of human recombinant hormone sensitive lipase (HSL)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHormone-sensitive lipase(Human)
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50147267(4-cyclohexyl-3-methyl-2-(4-methylpiperidine-1-carb...)
Affinity DataIC50: 4nMAssay Description:Inhibition of human recombinant hormone sensitive lipase (HSL)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHormone-sensitive lipase(Human)
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50147272(4-(2-methoxyethyl)-3-methyl-2-(4-m-tolylpiperidine...)
Affinity DataIC50: 4nMAssay Description:Inhibition of forskolin-stimulated lipolysis in differentiated 3T3-L1 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHormone-sensitive lipase(Human)
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50147270(3-methyl-4-(2-phenoxyethyl)-2-(piperidine-1-carbon...)
Affinity DataIC50: 4nMAssay Description:Inhibition of human recombinant hormone sensitive lipase (HSL)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHormone-sensitive lipase(Rat)
University of Jordan

Curated by ChEMBL
LigandPNGBDBM50138751(N-methyl-5-(methylthio)-N-phenyl-3-(4-(trifluorome...)
Affinity DataIC50: 4.41nMAssay Description:Inhibition of HSL in Wistar rat isolated fat cells by spectrophotometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHormone-sensitive lipase(Human)
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50147298(4-Isopropyl-3-methyl-5-oxo-5H-isoxazole-2-carboxyl...)
Affinity DataIC50: 5nMAssay Description:Inhibition of human recombinant hormone sensitive lipase (HSL)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHormone-sensitive lipase(Human)
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50142731([4-(Morpholin-4-ylcarbamoyloxy)-phenyl]-acetic aci...)
Affinity DataIC50: 5nMAssay Description:Inhibition of human recombinant hormone sensitive lipase.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHormone-sensitive lipase(Human)
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50147248(4-(2-methoxyethyl)-3-methyl-2-(4-phenylpiperidine-...)
Affinity DataIC50: 5nMAssay Description:Inhibition of forskolin-stimulated lipolysis in differentiated 3T3-L1 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
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