Compile Data Set for Download or QSAR
Report error Found 29 of ic50 data for polymerid = 50007894
TargetmRNA cap guanine-N7 methyltransferase(Human)
Federal University of Alagoas

Curated by ChEMBL
LigandPNGBDBM50378739(SINEFUNGIN | jm2c00120, Sinefungin)
Affinity DataIC50: 0.550nMAssay Description:Inhibition of human guanine-N7 methyltransferase expressed in Saccharomyces cerevisiae YBS40 (MATa leu2 ade2 trp1 his3 ura3 can1 abd1::hisGp360-ABD1)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetmRNA cap guanine-N7 methyltransferase(Human)
Federal University of Alagoas

Curated by ChEMBL
LigandPNGBDBM50378739(SINEFUNGIN | jm2c00120, Sinefungin)
Affinity DataIC50: 50nMAssay Description:Inhibition of N-terminal His6-tagged human RNA-N7 MTase expressed in Escherichia coli using GpppAC4 and [3H]SAM as substrate preincubated with enzyme...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetmRNA cap guanine-N7 methyltransferase(Human)
Federal University of Alagoas

Curated by ChEMBL
LigandPNGBDBM50378739(SINEFUNGIN | jm2c00120, Sinefungin)
Affinity DataIC50: 50nMAssay Description:Inhibition of N-terminus hexa-histidine tagged-human guanine-N7 methyltransferase expressed in Escherichia coli using GpppAC4 RNA as substrate incuba...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetmRNA cap guanine-N7 methyltransferase(Human)
Federal University of Alagoas

Curated by ChEMBL
LigandPNGBDBM50470559(CHEMBL4285979)
Affinity DataIC50: 779nMAssay Description:Inhibition of yeast 20S proteasome beta1 subunit using fluorescent substrate pretreated for 30 mins followed by substrate addition and measured after...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetmRNA cap guanine-N7 methyltransferase(Human)
Federal University of Alagoas

Curated by ChEMBL
LigandPNGBDBM50277889(CHEMBL451887 | CARFILZOMIB)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of yeast 20S proteasome beta1 subunit using fluorescent substrate pretreated for 30 mins followed by substrate addition and measured after...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetmRNA cap guanine-N7 methyltransferase(Human)
Federal University of Alagoas

Curated by ChEMBL
LigandPNGBDBM50277889(CHEMBL451887 | CARFILZOMIB)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of yeast 20S proteasome beta2 subunit using SUC-RLR-AMC as substrate pretreated for 30 mins followed by substrate addition and measured af...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetmRNA cap guanine-N7 methyltransferase(Human)
Federal University of Alagoas

Curated by ChEMBL
LigandPNGBDBM50470536(CHEMBL4292798)
Affinity DataIC50: 1.38E+3nMAssay Description:Inhibition of yeast 20S proteasome beta1 subunit using fluorescent substrate pretreated for 30 mins followed by substrate addition and measured after...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetmRNA cap guanine-N7 methyltransferase(Human)
Federal University of Alagoas

Curated by ChEMBL
LigandPNGBDBM50470539(CHEMBL4293877)
Affinity DataIC50: 2.48E+3nMAssay Description:Inhibition of yeast 20S proteasome beta1 subunit using fluorescent substrate pretreated for 30 mins followed by substrate addition and measured after...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetmRNA cap guanine-N7 methyltransferase(Human)
Federal University of Alagoas

Curated by ChEMBL
LigandPNGBDBM50470536(CHEMBL4292798)
Affinity DataIC50: 2.92E+3nMAssay Description:Inhibition of yeast 20S proteasome beta2 subunit using SUC-RLR-AMC as substrate pretreated for 30 mins followed by substrate addition and measured af...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetmRNA cap guanine-N7 methyltransferase(Human)
Federal University of Alagoas

Curated by ChEMBL
LigandPNGBDBM50470543(CHEMBL4286154)
Affinity DataIC50: 4.18E+3nMAssay Description:Inhibition of yeast 20S proteasome beta1 subunit using fluorescent substrate pretreated for 30 mins followed by substrate addition and measured after...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetmRNA cap guanine-N7 methyltransferase(Human)
Federal University of Alagoas

Curated by ChEMBL
LigandPNGBDBM50378739(SINEFUNGIN | jm2c00120, Sinefungin)
Affinity DataIC50: 5.30E+3nMAssay Description:Inhibition of human RNMT using GpppAC4 and [3H]AdoMet as substrate incubated for 30 mins by liquid scintillation counter analysisMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetmRNA cap guanine-N7 methyltransferase(Human)
Federal University of Alagoas

Curated by ChEMBL
LigandPNGBDBM50470559(CHEMBL4285979)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of yeast 20S proteasome beta2 subunit using SUC-RLR-AMC as substrate pretreated for 30 mins followed by substrate addition and measured af...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetmRNA cap guanine-N7 methyltransferase(Human)
Federal University of Alagoas

Curated by ChEMBL
LigandPNGBDBM50470544(CHEMBL4282765)
Affinity DataIC50: 1.02E+4nMAssay Description:Inhibition of yeast 20S proteasome beta1 subunit using fluorescent substrate pretreated for 30 mins followed by substrate addition and measured after...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetmRNA cap guanine-N7 methyltransferase(Human)
Federal University of Alagoas

Curated by ChEMBL
LigandPNGBDBM50565044(CHEMBL4778451)
Affinity DataIC50: 1.09E+4nMAssay Description:Inhibition of N-terminal His6-tagged human RNA-N7 MTase expressed in Escherichia coli using GpppAC4 and [3H]SAM as substrate preincubated with enzyme...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetmRNA cap guanine-N7 methyltransferase(Human)
Federal University of Alagoas

Curated by ChEMBL
LigandPNGBDBM50470543(CHEMBL4286154)
Affinity DataIC50: 1.46E+4nMAssay Description:Inhibition of yeast 20S proteasome beta2 subunit using SUC-RLR-AMC as substrate pretreated for 30 mins followed by substrate addition and measured af...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetmRNA cap guanine-N7 methyltransferase(Human)
Federal University of Alagoas

Curated by ChEMBL
LigandPNGBDBM50629784(CHEMBL5411560)
Affinity DataIC50: 1.61E+4nMAssay Description:Inhibition of N-terminal 6His-tagged human RNMT activity expressed in Escherichia coli C2566 using GpppAC4 synthetic RNA and [3H]-SAM as substrate in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetmRNA cap guanine-N7 methyltransferase(Human)
Federal University of Alagoas

Curated by ChEMBL
LigandPNGBDBM50470557(CHEMBL4290778)
Affinity DataIC50: 1.78E+4nMAssay Description:Inhibition of yeast 20S proteasome beta1 subunit using fluorescent substrate pretreated for 30 mins followed by substrate addition and measured after...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetmRNA cap guanine-N7 methyltransferase(Human)
Federal University of Alagoas

Curated by ChEMBL
LigandPNGBDBM50470539(CHEMBL4293877)
Affinity DataIC50: 2.61E+4nMAssay Description:Inhibition of yeast 20S proteasome beta2 subunit using SUC-RLR-AMC as substrate pretreated for 30 mins followed by substrate addition and measured af...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetmRNA cap guanine-N7 methyltransferase(Human)
Federal University of Alagoas

Curated by ChEMBL
LigandPNGBDBM50470557(CHEMBL4290778)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of yeast 20S proteasome beta2 subunit using SUC-RLR-AMC as substrate pretreated for 30 mins followed by substrate addition and measured af...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetmRNA cap guanine-N7 methyltransferase(Human)
Federal University of Alagoas

Curated by ChEMBL
LigandPNGBDBM50629779(CHEMBL5438762)
Affinity DataIC50: 5.62E+4nMAssay Description:Inhibition of N-terminal 6His-tagged human RNMT activity expressed in Escherichia coli C2566 using GpppAC4 synthetic RNA and [3H]-SAM as substrate in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetmRNA cap guanine-N7 methyltransferase(Human)
Federal University of Alagoas

Curated by ChEMBL
LigandPNGBDBM50629789(CHEMBL5401656)
Affinity DataIC50: 5.65E+4nMAssay Description:Inhibition of N-terminal 6His-tagged human RNMT activity expressed in Escherichia coli C2566 using GpppAC4 synthetic RNA and [3H]-SAM as substrate in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetmRNA cap guanine-N7 methyltransferase(Human)
Federal University of Alagoas

Curated by ChEMBL
LigandPNGBDBM50470544(CHEMBL4282765)
Affinity DataIC50: 6.16E+4nMAssay Description:Inhibition of yeast 20S proteasome beta2 subunit using SUC-RLR-AMC as substrate pretreated for 30 mins followed by substrate addition and measured af...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetmRNA cap guanine-N7 methyltransferase(Human)
Federal University of Alagoas

Curated by ChEMBL
LigandPNGBDBM50629794(CHEMBL5396377)
Affinity DataIC50: 1.65E+5nMAssay Description:Inhibition of N-terminal 6His-tagged human RNMT activity expressed in Escherichia coli C2566 using GpppAC4 synthetic RNA and [3H]-SAM as substrate in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetmRNA cap guanine-N7 methyltransferase(Human)
Federal University of Alagoas

Curated by ChEMBL
LigandPNGBDBM50565048(CHEMBL4794760)
Affinity DataIC50: 1.69E+5nMAssay Description:Inhibition of N-terminal His6-tagged human RNA-N7 MTase expressed in Escherichia coli using GpppAC4 and [3H]SAM as substrate preincubated with enzyme...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetmRNA cap guanine-N7 methyltransferase(Human)
Federal University of Alagoas

Curated by ChEMBL
LigandPNGBDBM50565050(CHEMBL4793508)
Affinity DataIC50: 2.48E+5nMAssay Description:Inhibition of N-terminal His6-tagged human RNA-N7 MTase expressed in Escherichia coli using GpppAC4 and [3H]SAM as substrate preincubated with enzyme...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetmRNA cap guanine-N7 methyltransferase(Human)
Federal University of Alagoas

Curated by ChEMBL
LigandPNGBDBM50565049(CHEMBL4798931)
Affinity DataIC50: 2.76E+5nMAssay Description:Inhibition of N-terminal His6-tagged human RNA-N7 MTase expressed in Escherichia coli using GpppAC4 and [3H]SAM as substrate preincubated with enzyme...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetmRNA cap guanine-N7 methyltransferase(Human)
Federal University of Alagoas

Curated by ChEMBL
LigandPNGBDBM50565047(CHEMBL4780071)
Affinity DataIC50: 5.00E+5nMAssay Description:Inhibition of N-terminal His6-tagged human RNA-N7 MTase expressed in Escherichia coli using GpppAC4 and [3H]SAM as substrate preincubated with enzyme...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetmRNA cap guanine-N7 methyltransferase(Human)
Federal University of Alagoas

Curated by ChEMBL
LigandPNGBDBM50565046(CHEMBL4794435)
Affinity DataIC50: 5.00E+5nMAssay Description:Inhibition of N-terminal His6-tagged human RNA-N7 MTase expressed in Escherichia coli using GpppAC4 and [3H]SAM as substrate preincubated with enzyme...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetmRNA cap guanine-N7 methyltransferase(Human)
Federal University of Alagoas

Curated by ChEMBL
LigandPNGBDBM50565045(CHEMBL4776021)
Affinity DataIC50: 5.00E+5nMAssay Description:Inhibition of N-terminal His6-tagged human RNA-N7 MTase expressed in Escherichia coli using GpppAC4 and [3H]SAM as substrate preincubated with enzyme...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed