Compile Data Set for Download or QSAR
Report error Found 73 of ic50 data for polymerid = 50007384
TargetProtein mono-ADP-ribosyltransferase PARP11(Human)
University of Oulu

Curated by ChEMBL
LigandPNGBDBM50594012(CHEMBL5191676)
Affinity DataIC50: 14nMAssay Description:Inhibition of human full length PARP11 expressed in Escherichia coli BL21 (DE3) competent cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein mono-ADP-ribosyltransferase PARP11(Human)
University of Oulu

Curated by ChEMBL
LigandPNGBDBM50594012(CHEMBL5191676)
Affinity DataIC50: 14nMAssay Description:Inhibition of PARP11 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetProtein mono-ADP-ribosyltransferase PARP11(Human)
University of Oulu

Curated by ChEMBL
LigandPNGBDBM50594012(CHEMBL5191676)
Affinity DataIC50: 14nMAssay Description:Inhibition of human full length GFP-tagged PARP11 in human HeLa cells incubated for 3 hrs by chemiluminescence based analysisMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetProtein mono-ADP-ribosyltransferase PARP11(Human)
University of Oulu

Curated by ChEMBL
LigandPNGBDBM50593627(CHEMBL5199558)
Affinity DataIC50: 67nMAssay Description:Inhibition of N-terminal GST-tagged/C-terminal 6xHis-tagged human recombinant PARP11 (8 to 338 residues) expressed in Sf9 insect cells by chemilumine...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetProtein mono-ADP-ribosyltransferase PARP11(Human)
University of Oulu

Curated by ChEMBL
LigandPNGBDBM50594250(CHEMBL5207717)
Affinity DataIC50: 99nMAssay Description:Inhibition of PARP11 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails
PubMed
TargetProtein mono-ADP-ribosyltransferase PARP11(Human)
University of Oulu

Curated by ChEMBL
LigandPNGBDBM50084621(BMN 673 | Talazoparib)
Affinity DataIC50: 140nMAssay Description:Inhibition of human N-terminal FLAG-tagged/C-terminal His-tagged recombinant PARP11 (8 to 338 (end) residues) expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetProtein mono-ADP-ribosyltransferase PARP11(Human)
University of Oulu

Curated by ChEMBL
LigandPNGBDBM50590269(CHEMBL5187963)
Affinity DataIC50: 200nMAssay Description:Inhibition of N-terminal His-tagged full length human PARP11 expressed in Escherichia coli BL21 (DE3) preincubated with 6-a-NAD+ for 5 to 10 mins fol...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetProtein mono-ADP-ribosyltransferase PARP11(Human)
University of Oulu

Curated by ChEMBL
LigandPNGBDBM50616441(CHEMBL5404785)
Affinity DataIC50: 240nMAssay Description:Inhibition of N-terminal MBP tagged/C-terminal PARP11 (unknown origin) expressed in Escherichia coli in presence of NAD+ by proximity enhanced assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails Article
PubMed
TargetProtein mono-ADP-ribosyltransferase PARP11(Human)
University of Oulu

Curated by ChEMBL
LigandPNGBDBM50616435(CHEMBL5431108)
Affinity DataIC50: 470nMAssay Description:Inhibition of N-terminal MBP tagged/C-terminal PARP11 (unknown origin) expressed in Escherichia coli in presence of NAD+ by proximity enhanced assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetProtein mono-ADP-ribosyltransferase PARP11(Human)
University of Oulu

Curated by ChEMBL
LigandPNGBDBM50594249(CHEMBL5186007)
Affinity DataIC50: 550nMAssay Description:Inhibition of PARP11 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails
PubMed
TargetProtein mono-ADP-ribosyltransferase PARP11(Human)
University of Oulu

Curated by ChEMBL
LigandPNGBDBM50503870(CHEMBL4580007)
Affinity DataIC50: 1.18E+3nMAssay Description:Inhibition of full length human His-SUMO-tagged PARP11 expressed in Escherichia coli BL21 assessed as reduction in MARylation of His6-tagged SRPK2 su...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein mono-ADP-ribosyltransferase PARP11(Human)
University of Oulu

Curated by ChEMBL
LigandPNGBDBM50503870(CHEMBL4580007)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of full length human His-SUMO-tagged PARP11 expressed in Escherichia coli BL21 assessed as reduction in MARylation of His6-tagged SRPK2 su...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein mono-ADP-ribosyltransferase PARP11(Human)
University of Oulu

Curated by ChEMBL
LigandPNGBDBM199181(4-[(4-Carbamoylcyclohexyl)oxy]cyclohexane-1-carbox...)
Affinity DataIC50: 2.09E+3nMAssay Description:Inhibition of full length human His-SUMO-tagged PARP11 expressed in Escherichia coli BL21 assessed as reduction in MARylation of His6-tagged SRPK2 su...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein mono-ADP-ribosyltransferase PARP11(Human)
University of Oulu

Curated by ChEMBL
LigandPNGBDBM199181(4-[(4-Carbamoylcyclohexyl)oxy]cyclohexane-1-carbox...)
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of full length human His-SUMO-tagged PARP11 expressed in Escherichia coli BL21 assessed as reduction in MARylation of His6-tagged SRPK2 su...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein mono-ADP-ribosyltransferase PARP11(Human)
University of Oulu

Curated by ChEMBL
LigandPNGBDBM27682(5-methyl-1,2,3,4-tetrahydroisoquinolin-1-one | CHE...)
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of full length human His-SUMO-tagged PARP11 expressed in Escherichia coli BL21 assessed as reduction in MARylation of His6-tagged SRPK2 su...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein mono-ADP-ribosyltransferase PARP11(Human)
University of Oulu

Curated by ChEMBL
LigandPNGBDBM27682(5-methyl-1,2,3,4-tetrahydroisoquinolin-1-one | CHE...)
Affinity DataIC50: 2.14E+3nMAssay Description:Inhibition of full length human His-SUMO-tagged PARP11 expressed in Escherichia coli BL21 assessed as reduction in MARylation of His6-tagged SRPK2 su...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein mono-ADP-ribosyltransferase PARP11(Human)
University of Oulu

Curated by ChEMBL
LigandPNGBDBM50628429(CHEMBL5402698)
Affinity DataIC50: 2.17E+3nMAssay Description:Inhibition of PARP11 (unknown origin) using biotinylated NAD+ as substrate by luminescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetProtein mono-ADP-ribosyltransferase PARP11(Human)
University of Oulu

Curated by ChEMBL
LigandPNGBDBM431646(5-[[(2S)-1-(3-Oxo-3-[4-[5-(trifluoromethyl)pyrimid...)
Affinity DataIC50: 2.28E+3nMAssay Description:Inhibition of human recombinant N-terminal GST-tagged / C-terminal His-tagged PARP11 (8 to 338 end residues) expressed in baculovirus infected Sf9 ce...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetProtein mono-ADP-ribosyltransferase PARP11(Human)
University of Oulu

Curated by ChEMBL
LigandPNGBDBM207624(US9260440, 69 | US9617273, Example 69 | US10501467...)
Affinity DataIC50: 2.70E+3nMAssay Description:Inhibition of PARP-11 (unknown origin) pre-incubated for 30 mins before addition of activated DNA and NAD by chemiluminescent assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein mono-ADP-ribosyltransferase PARP11(Human)
University of Oulu

Curated by ChEMBL
LigandPNGBDBM50503852(CHEMBL4470303)
Affinity DataIC50: 2.88E+3nMAssay Description:Inhibition of full length human His-SUMO-tagged PARP11 expressed in Escherichia coli BL21 assessed as reduction in MARylation of His6-tagged SRPK2 su...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein mono-ADP-ribosyltransferase PARP11(Human)
University of Oulu

Curated by ChEMBL
LigandPNGBDBM50503852(CHEMBL4470303)
Affinity DataIC50: 2.90E+3nMAssay Description:Inhibition of full length human His-SUMO-tagged PARP11 expressed in Escherichia coli BL21 assessed as reduction in MARylation of His6-tagged SRPK2 su...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein mono-ADP-ribosyltransferase PARP11(Human)
University of Oulu

Curated by ChEMBL
LigandPNGBDBM50503857(CHEMBL4455412)
Affinity DataIC50: 4.17E+3nMAssay Description:Inhibition of full length human His-SUMO-tagged PARP11 expressed in Escherichia coli BL21 assessed as reduction in MARylation of His6-tagged SRPK2 su...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetProtein mono-ADP-ribosyltransferase PARP11(Human)
University of Oulu

Curated by ChEMBL
LigandPNGBDBM50503857(CHEMBL4455412)
Affinity DataIC50: 4.20E+3nMAssay Description:Inhibition of full length human His-SUMO-tagged PARP11 expressed in Escherichia coli BL21 assessed as reduction in MARylation of His6-tagged SRPK2 su...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetProtein mono-ADP-ribosyltransferase PARP11(Human)
University of Oulu

Curated by ChEMBL
LigandPNGBDBM50503864(CHEMBL4573527)
Affinity DataIC50: 4.57E+3nMAssay Description:Inhibition of full length human His-SUMO-tagged PARP11 expressed in Escherichia coli BL21 assessed as reduction in MARylation of His6-tagged SRPK2 su...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetProtein mono-ADP-ribosyltransferase PARP11(Human)
University of Oulu

Curated by ChEMBL
LigandPNGBDBM50503864(CHEMBL4573527)
Affinity DataIC50: 4.60E+3nMAssay Description:Inhibition of full length human His-SUMO-tagged PARP11 expressed in Escherichia coli BL21 assessed as reduction in MARylation of His6-tagged SRPK2 su...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetProtein mono-ADP-ribosyltransferase PARP11(Human)
University of Oulu

Curated by ChEMBL
LigandPNGBDBM50503854(CHEMBL4577063)
Affinity DataIC50: 4.90E+3nMAssay Description:Inhibition of full length human His-SUMO-tagged PARP11 expressed in Escherichia coli BL21 assessed as reduction in MARylation of His6-tagged SRPK2 su...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetProtein mono-ADP-ribosyltransferase PARP11(Human)
University of Oulu

Curated by ChEMBL
LigandPNGBDBM50503854(CHEMBL4577063)
Affinity DataIC50: 4.90E+3nMAssay Description:Inhibition of full length human His-SUMO-tagged PARP11 expressed in Escherichia coli BL21 assessed as reduction in MARylation of His6-tagged SRPK2 su...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetProtein mono-ADP-ribosyltransferase PARP11(Human)
University of Oulu

Curated by ChEMBL
LigandPNGBDBM50238419(CHEMBL4060134)
Affinity DataIC50: 5.01E+3nMAssay Description:Binding affinity to PARP11 in human Jurkat cell extract after 45 mins by mass spectrometric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein mono-ADP-ribosyltransferase PARP11(Human)
University of Oulu

Curated by ChEMBL
LigandPNGBDBM50238416(CHEMBL4087470)
Affinity DataIC50: 5.01E+3nMAssay Description:Binding affinity to PARP11 in human Jurkat cell extract after 45 mins by mass spectrometric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein mono-ADP-ribosyltransferase PARP11(Human)
University of Oulu

Curated by ChEMBL
LigandPNGBDBM50188594(CHEMBL1086580 | CHEBI:62878 | US20240279201, Compo...)
Affinity DataIC50: 5.01E+3nMAssay Description:Binding affinity to PARP11 in human Jurkat cell extract after 45 mins by mass spectrometric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein mono-ADP-ribosyltransferase PARP11(Human)
University of Oulu

Curated by ChEMBL
LigandPNGBDBM50238428(CHEMBL4087876)
Affinity DataIC50: 5.01E+3nMAssay Description:Binding affinity to PARP11 in human Jurkat cell extract after 45 mins by mass spectrometric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein mono-ADP-ribosyltransferase PARP11(Human)
University of Oulu

Curated by ChEMBL
LigandPNGBDBM50238425(CHEMBL4064332)
Affinity DataIC50: 5.01E+3nMAssay Description:Binding affinity to PARP11 in human Jurkat cell extract after 45 mins by mass spectrometric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein mono-ADP-ribosyltransferase PARP11(Human)
University of Oulu

Curated by ChEMBL
LigandPNGBDBM50503863(CHEMBL4450751)
Affinity DataIC50: 5.75E+3nMAssay Description:Inhibition of full length human His-SUMO-tagged PARP11 expressed in Escherichia coli BL21 assessed as reduction in MARylation of His6-tagged SRPK2 su...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetProtein mono-ADP-ribosyltransferase PARP11(Human)
University of Oulu

Curated by ChEMBL
LigandPNGBDBM50503863(CHEMBL4450751)
Affinity DataIC50: 5.80E+3nMAssay Description:Inhibition of full length human His-SUMO-tagged PARP11 expressed in Escherichia coli BL21 assessed as reduction in MARylation of His6-tagged SRPK2 su...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetProtein mono-ADP-ribosyltransferase PARP11(Human)
University of Oulu

Curated by ChEMBL
LigandPNGBDBM50503869(CHEMBL4572268)
Affinity DataIC50: 6.03E+3nMAssay Description:Inhibition of full length human His-SUMO-tagged PARP11 expressed in Escherichia coli BL21 assessed as reduction in MARylation of His6-tagged SRPK2 su...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetProtein mono-ADP-ribosyltransferase PARP11(Human)
University of Oulu

Curated by ChEMBL
LigandPNGBDBM50503869(CHEMBL4572268)
Affinity DataIC50: 6.10E+3nMAssay Description:Inhibition of full length human His-SUMO-tagged PARP11 expressed in Escherichia coli BL21 assessed as reduction in MARylation of His6-tagged SRPK2 su...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetProtein mono-ADP-ribosyltransferase PARP11(Human)
University of Oulu

Curated by ChEMBL
LigandPNGBDBM27566(4-({3-[(4-cyclopropanecarbonylpiperazin-1-yl)carbo...)
Affinity DataIC50: 7.81E+3nMAssay Description:Inhibition of PARP11 (unknown origin) using biotinylated NAD+ as substrate by luminescence assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetProtein mono-ADP-ribosyltransferase PARP11(Human)
University of Oulu

Curated by ChEMBL
LigandPNGBDBM50339016(3,4-dihydroisoquinolin-1(2H)-one | CHEMBL1688212)
Affinity DataIC50: 7.94E+3nMAssay Description:Inhibition of full length human His-SUMO-tagged PARP11 expressed in Escherichia coli BL21 assessed as reduction in MARylation of His6-tagged SRPK2 su...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein mono-ADP-ribosyltransferase PARP11(Human)
University of Oulu

Curated by ChEMBL
LigandPNGBDBM50339016(3,4-dihydroisoquinolin-1(2H)-one | CHEMBL1688212)
Affinity DataIC50: 8.00E+3nMAssay Description:Inhibition of full length human His-SUMO-tagged PARP11 expressed in Escherichia coli BL21 assessed as reduction in MARylation of His6-tagged SRPK2 su...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein mono-ADP-ribosyltransferase PARP11(Human)
University of Oulu

Curated by ChEMBL
LigandPNGBDBM50503862(CHEMBL4565850)
Affinity DataIC50: 8.70E+3nMAssay Description:Inhibition of full length human His-SUMO-tagged PARP11 expressed in Escherichia coli BL21 assessed as reduction in MARylation of His6-tagged SRPK2 su...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein mono-ADP-ribosyltransferase PARP11(Human)
University of Oulu

Curated by ChEMBL
LigandPNGBDBM50503862(CHEMBL4565850)
Affinity DataIC50: 8.71E+3nMAssay Description:Inhibition of full length human His-SUMO-tagged PARP11 expressed in Escherichia coli BL21 assessed as reduction in MARylation of His6-tagged SRPK2 su...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein mono-ADP-ribosyltransferase PARP11(Human)
University of Oulu

Curated by ChEMBL
LigandPNGBDBM50616430(CHEMBL5406267)
Affinity DataIC50: 9.40E+3nMAssay Description:Inhibition of N-terminal MBP tagged/C-terminal PARP11 (unknown origin) expressed in Escherichia coli in presence of NAD+ by proximity enhanced assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails Article
PubMed
TargetProtein mono-ADP-ribosyltransferase PARP11(Human)
University of Oulu

Curated by ChEMBL
LigandPNGBDBM50505333(CHEMBL4437173)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human N-terminal GST-tagged PARP11 (8 to 338 residues) expressed in baculovirus infected Sf9 insect cells using biotinylated substrate ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein mono-ADP-ribosyltransferase PARP11(Human)
University of Oulu

Curated by ChEMBL
LigandPNGBDBM50503858(CHEMBL4462418)
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of full length human His-SUMO-tagged PARP11 expressed in Escherichia coli BL21 assessed as reduction in MARylation of His6-tagged SRPK2 su...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetProtein mono-ADP-ribosyltransferase PARP11(Human)
University of Oulu

Curated by ChEMBL
LigandPNGBDBM50503858(CHEMBL4462418)
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of full length human His-SUMO-tagged PARP11 expressed in Escherichia coli BL21 assessed as reduction in MARylation of His6-tagged SRPK2 su...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetProtein mono-ADP-ribosyltransferase PARP11(Human)
University of Oulu

Curated by ChEMBL
LigandPNGBDBM50503861(CHEMBL4565268)
Affinity DataIC50: 1.35E+4nMAssay Description:Inhibition of full length human His-SUMO-tagged PARP11 expressed in Escherichia coli BL21 assessed as reduction in MARylation of His6-tagged SRPK2 su...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein mono-ADP-ribosyltransferase PARP11(Human)
University of Oulu

Curated by ChEMBL
LigandPNGBDBM50503861(CHEMBL4565268)
Affinity DataIC50: 1.35E+4nMAssay Description:Inhibition of full length human His-SUMO-tagged PARP11 expressed in Escherichia coli BL21 assessed as reduction in MARylation of His6-tagged SRPK2 su...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein mono-ADP-ribosyltransferase PARP11(Human)
University of Oulu

Curated by ChEMBL
LigandPNGBDBM50503851(CHEMBL4585230)
Affinity DataIC50: 1.38E+4nMAssay Description:Inhibition of full length human His-SUMO-tagged PARP11 expressed in Escherichia coli BL21 assessed as reduction in MARylation of His6-tagged SRPK2 su...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetProtein mono-ADP-ribosyltransferase PARP11(Human)
University of Oulu

Curated by ChEMBL
LigandPNGBDBM50503851(CHEMBL4585230)
Affinity DataIC50: 1.40E+4nMAssay Description:Inhibition of full length human His-SUMO-tagged PARP11 expressed in Escherichia coli BL21 assessed as reduction in MARylation of His6-tagged SRPK2 su...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetProtein mono-ADP-ribosyltransferase PARP11(Human)
University of Oulu

Curated by ChEMBL
LigandPNGBDBM50503871(CHEMBL4515501)
Affinity DataIC50: 1.66E+4nMAssay Description:Inhibition of full length human His-SUMO-tagged PARP11 expressed in Escherichia coli BL21 assessed as reduction in MARylation of His6-tagged SRPK2 su...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
Displayed 1 to 50 (of 73 total ) | Next | Last >>
Jump to: