Compile Data Set for Download or QSAR
Report error Found 34 of ic50 data for polymerid = 50007318
TargetProtein mono-ADP-ribosyltransferase PARP16(Human)
Shandong First Medical University and Shandong Academy of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50609916(CHEMBL5284069)
Affinity DataIC50: 362nMAssay Description:Inhibition of PARP16 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetProtein mono-ADP-ribosyltransferase PARP16(Human)
Shandong First Medical University and Shandong Academy of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50594267(CHEMBL5189477)
Affinity DataIC50: 362nMAssay Description:Inhibition of PARP16 (unknown origin) using IRE-1 as substrate incubated for 1 hr by chemiluminescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetProtein mono-ADP-ribosyltransferase PARP16(Human)
Shandong First Medical University and Shandong Academy of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50594267(CHEMBL5189477)
Affinity DataIC50: 362nMAssay Description:Inhibition of PARP16 (unknown origin) using 6xHis-tagged IRE-1 as substrate incubated for 1 hr by chemiluminescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetProtein mono-ADP-ribosyltransferase PARP16(Human)
Shandong First Medical University and Shandong Academy of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50594266(CHEMBL5172255)
Affinity DataIC50: 427nMAssay Description:Inhibition of PARP16 (unknown origin) using IRE-1 as substrate incubated for 1 hr by chemiluminescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetProtein mono-ADP-ribosyltransferase PARP16(Human)
Shandong First Medical University and Shandong Academy of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50242630(CHEMBL4089522)
Affinity DataIC50: 560nMAssay Description:Inhibition of His6-tagged PARP16 (unknown origin) preincubated for 15 mins followed by biotinylated NAD+ addition by chemiluminescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein mono-ADP-ribosyltransferase PARP16(Human)
Shandong First Medical University and Shandong Academy of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50145156(CHEMBL3764816)
Affinity DataIC50: 1.86E+3nMAssay Description:Inhibition of full length recombinant human His6-tagged PARP16 expressed in Escherichia coli BL21(DE3) preincubated for 15 mins followed by biotinyla...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein mono-ADP-ribosyltransferase PARP16(Human)
Shandong First Medical University and Shandong Academy of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50145156(CHEMBL3764816)
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of full length recombinant human His6-tagged PARP16 expressed in Escherichia coli BL21(DE3) preincubated for 15 mins followed by biotinyla...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein mono-ADP-ribosyltransferase PARP16(Human)
Shandong First Medical University and Shandong Academy of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50616441(CHEMBL5404785)
Affinity DataIC50: 3.40E+3nMAssay Description:Inhibition of N-terminal MBP tagged/C-terminal PARP16 (unknown origin) expressed in Escherichia coli in presence of NAD+ by proximity enhanced assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails Article
PubMed
TargetProtein mono-ADP-ribosyltransferase PARP16(Human)
Shandong First Medical University and Shandong Academy of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM199181(4-[(4-Carbamoylcyclohexyl)oxy]cyclohexane-1-carbox...)
Affinity DataIC50: 4.20E+3nMAssay Description:Inhibition of N-terminal His-tagged human ARTD15 (1 to 280 residues) expressed in Escherichia coli Rosetta2 (DE3) after 24 hrs in presence of NAD+More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein mono-ADP-ribosyltransferase PARP16(Human)
Shandong First Medical University and Shandong Academy of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50238428(CHEMBL4087876)
Affinity DataIC50: 5.01E+3nMAssay Description:Binding affinity to PARP16 in human Jurkat cell extract after 45 mins by mass spectrometric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein mono-ADP-ribosyltransferase PARP16(Human)
Shandong First Medical University and Shandong Academy of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50238416(CHEMBL4087470)
Affinity DataIC50: 5.01E+3nMAssay Description:Binding affinity to PARP16 in human Jurkat cell extract after 45 mins by mass spectrometric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein mono-ADP-ribosyltransferase PARP16(Human)
Shandong First Medical University and Shandong Academy of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50238425(CHEMBL4064332)
Affinity DataIC50: 5.01E+3nMAssay Description:Binding affinity to PARP16 in human Jurkat cell extract after 45 mins by mass spectrometric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein mono-ADP-ribosyltransferase PARP16(Human)
Shandong First Medical University and Shandong Academy of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50188594(CHEMBL1086580 | CHEBI:62878 | US20240279201, Compo...)
Affinity DataIC50: 5.01E+3nMAssay Description:Binding affinity to PARP16 in human Jurkat cell extract after 45 mins by mass spectrometric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein mono-ADP-ribosyltransferase PARP16(Human)
Shandong First Medical University and Shandong Academy of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50238419(CHEMBL4060134)
Affinity DataIC50: 5.01E+3nMAssay Description:Binding affinity to PARP16 in human Jurkat cell extract after 45 mins by mass spectrometric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein mono-ADP-ribosyltransferase PARP16(Human)
Shandong First Medical University and Shandong Academy of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM27566(4-({3-[(4-cyclopropanecarbonylpiperazin-1-yl)carbo...)
Affinity DataIC50: 5.10E+3nMAssay Description:Inhibition of full length recombinant human His6-tagged PARP16 expressed in Escherichia coli BL21(DE3) preincubated for 15 mins followed by biotinyla...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein mono-ADP-ribosyltransferase PARP16(Human)
Shandong First Medical University and Shandong Academy of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM27566(4-({3-[(4-cyclopropanecarbonylpiperazin-1-yl)carbo...)
Affinity DataIC50: 5.13E+3nMAssay Description:Inhibition of full length recombinant human His6-tagged PARP16 expressed in Escherichia coli BL21(DE3) preincubated for 15 mins followed by biotinyla...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein mono-ADP-ribosyltransferase PARP16(Human)
Shandong First Medical University and Shandong Academy of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50616435(CHEMBL5431108)
Affinity DataIC50: 5.20E+3nMAssay Description:Inhibition of N-terminal MBP tagged/C-terminal PARP16 (unknown origin) expressed in Escherichia coli in presence of NAD+ by proximity enhanced assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetProtein mono-ADP-ribosyltransferase PARP16(Human)
Shandong First Medical University and Shandong Academy of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50503853(CHEMBL4545565)
Affinity DataIC50: 6.70E+3nMAssay Description:Inhibition of human transmembrane domain deficient His-SUMO-tagged PARP16 expressed in Escherichia coli BL21 assessed as reduction in MARylation of H...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetProtein mono-ADP-ribosyltransferase PARP16(Human)
Shandong First Medical University and Shandong Academy of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50503853(CHEMBL4545565)
Affinity DataIC50: 6.76E+3nMAssay Description:Inhibition of human transmembrane domain deficient His-SUMO-tagged PARP16 expressed in Escherichia coli BL21 assessed as reduction in MARylation of H...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetProtein mono-ADP-ribosyltransferase PARP16(Human)
Shandong First Medical University and Shandong Academy of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50593992(CHEMBL5186967)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human PARP16More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails
PubMed
TargetProtein mono-ADP-ribosyltransferase PARP16(Human)
Shandong First Medical University and Shandong Academy of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50616430(CHEMBL5406267)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of N-terminal MBP tagged/C-terminal PARP16 (unknown origin) expressed in Escherichia coli in presence of NAD+ by proximity enhanced assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails Article
PubMed
TargetProtein mono-ADP-ribosyltransferase PARP16(Human)
Shandong First Medical University and Shandong Academy of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50594011(CHEMBL5200521)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human PARP16More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetProtein mono-ADP-ribosyltransferase PARP16(Human)
Shandong First Medical University and Shandong Academy of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50594010(CHEMBL5200358)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human PARP16More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetProtein mono-ADP-ribosyltransferase PARP16(Human)
Shandong First Medical University and Shandong Academy of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50594005(CHEMBL5181947)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human PARP16More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetProtein mono-ADP-ribosyltransferase PARP16(Human)
Shandong First Medical University and Shandong Academy of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50468581(CHEMBL4287655)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of N-terminal His-tagged human ARTD15 (1 to 280 residues) expressed in Escherichia coli Rosetta2 (DE3) after 24 hrs in presence of NAD+More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetProtein mono-ADP-ribosyltransferase PARP16(Human)
Shandong First Medical University and Shandong Academy of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50340090(4-methoxybenzamide | CHEMBL449635)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of N-terminal His-tagged human ARTD15 (1 to 280 residues) expressed in Escherichia coli Rosetta2 (DE3) after 24 hrs in presence of NAD+More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein mono-ADP-ribosyltransferase PARP16(Human)
Shandong First Medical University and Shandong Academy of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50468579(CHEMBL4287262)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of N-terminal His-tagged human ARTD15 (1 to 280 residues) expressed in Escherichia coli Rosetta2 (DE3) after 24 hrs in presence of NAD+More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein mono-ADP-ribosyltransferase PARP16(Human)
Shandong First Medical University and Shandong Academy of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50452662(CHEMBL4208737)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of N-terminal His-tagged human ARTD15 (1 to 280 residues) expressed in Escherichia coli Rosetta2 (DE3) after 24 hrs in presence of NAD+More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein mono-ADP-ribosyltransferase PARP16(Human)
Shandong First Medical University and Shandong Academy of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50250875(CHEMBL4095003)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human PARP16 using NAD+ as substrate by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetProtein mono-ADP-ribosyltransferase PARP16(Human)
Shandong First Medical University and Shandong Academy of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM431646(5-[[(2S)-1-(3-Oxo-3-[4-[5-(trifluoromethyl)pyrimid...)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of PARP16 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetProtein mono-ADP-ribosyltransferase PARP16(Human)
Shandong First Medical University and Shandong Academy of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50234916(CHEMBL4098188)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of PARP16 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein mono-ADP-ribosyltransferase PARP16(Human)
Shandong First Medical University and Shandong Academy of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50234915(CHEMBL4069447)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of PARP16 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein mono-ADP-ribosyltransferase PARP16(Human)
Shandong First Medical University and Shandong Academy of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50594268(CHEMBL5178746)
Affinity DataIC50: 2.96E+5nMAssay Description:Inhibition of PARP16 (unknown origin) using IRE-1 as substrate incubated for 1 hr by chemiluminescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetProtein mono-ADP-ribosyltransferase PARP16(Human)
Shandong First Medical University and Shandong Academy of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50594268(CHEMBL5178746)
Affinity DataIC50: 2.96E+5nMAssay Description:Inhibition of PARP16 (unknown origin) using 6xHis-tagged IRE-1 as substrate incubated for 1 hr by chemiluminescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed