Compile Data Set for Download or QSAR
Report error Found 48 of ic50 data for polymerid = 50006705
TargetProtein polybromo-1(Human)
Constellation, A Morphosys

Curated by ChEMBL
LigandPNGBDBM394583(US10308614, Example 186 | 2-(6-amino-5-phenylpyrid...)
Affinity DataIC50: 8.90nMAssay Description:Inhibition of PBRM1 bromodomain 5 (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetProtein polybromo-1(Human)
Constellation, A Morphosys

Curated by ChEMBL
LigandPNGBDBM50591380(CHEMBL5180611 | US20240190828, Compound 34)
Affinity DataIC50: 160nMAssay Description:Inhibition of biotinylated histone H3K14 (1 to 20 residues) peptide binding to His6-tagged recombinant human PBRM1 BD2 transfected in Escherichia col...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetProtein polybromo-1(Human)
Constellation, A Morphosys

Curated by ChEMBL
LigandPNGBDBM50591362(CHEMBL5195502 | US20240190828, Compound 15)
Affinity DataIC50: 200nMAssay Description:Inhibition of biotinylated histone H3K14 (1 to 20 residues) peptide binding to His6-tagged recombinant human PBRM1 BD2 transfected in Escherichia col...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetProtein polybromo-1(Human)
Constellation, A Morphosys

Curated by ChEMBL
LigandPNGBDBM50184981(CHEMBL3823055 | US20240190828, Compound 7)
Affinity DataIC50: 200nMAssay Description:Inhibition of biotinylated histone H3K14 (1 to 20 residues) peptide binding to His6-tagged recombinant human PBRM1 BD2 transfected in Escherichia col...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetProtein polybromo-1(Human)
Constellation, A Morphosys

Curated by ChEMBL
LigandPNGBDBM50591371(CHEMBL5187356 | US20240190828, Compound 25)
Affinity DataIC50: 220nMAssay Description:Inhibition of biotinylated histone H3K14 (1 to 20 residues) peptide binding to His6-tagged recombinant human PBRM1 BD2 transfected in Escherichia col...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetProtein polybromo-1(Human)
Constellation, A Morphosys

Curated by ChEMBL
LigandPNGBDBM50591363(CHEMBL5170275 | US20240190828, Compound 16)
Affinity DataIC50: 260nMAssay Description:Inhibition of biotinylated histone H3K14 (1 to 20 residues) peptide binding to His6-tagged recombinant human PBRM1 BD2 transfected in Escherichia col...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetProtein polybromo-1(Human)
Constellation, A Morphosys

Curated by ChEMBL
LigandPNGBDBM50591372(CHEMBL5207236 | US20240190828, Compound 26)
Affinity DataIC50: 290nMAssay Description:Inhibition of biotinylated histone H3K14 (1 to 20 residues) peptide binding to His6-tagged recombinant human PBRM1 BD2 transfected in Escherichia col...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetProtein polybromo-1(Human)
Constellation, A Morphosys

Curated by ChEMBL
LigandPNGBDBM50591381(CHEMBL5184118)
Affinity DataIC50: 290nMAssay Description:Inhibition of biotinylated histone H3K14 (1 to 20 residues) peptide binding to His6-tagged recombinant human PBRM1 BD2 transfected in Escherichia col...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetProtein polybromo-1(Human)
Constellation, A Morphosys

Curated by ChEMBL
LigandPNGBDBM50591370(CHEMBL5185774 | US20240190828, Compound 24)
Affinity DataIC50: 430nMAssay Description:Inhibition of biotinylated histone H3K14 (1 to 20 residues) peptide binding to His6-tagged recombinant human PBRM1 BD2 transfected in Escherichia col...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetProtein polybromo-1(Human)
Constellation, A Morphosys

Curated by ChEMBL
LigandPNGBDBM50266286(CHEMBL4650213)
Affinity DataIC50: 550nMAssay Description:Alphascreen assay. Binding to PB1A (domain start/stop: S613-D734) by alphascreen assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein polybromo-1(Human)
Constellation, A Morphosys

Curated by ChEMBL
LigandPNGBDBM50028142(CHEMBL2177300)
Affinity DataIC50: 631nMAssay Description:Inhibition of human PBRM1 bromodomain 1 by BROMOscan assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein polybromo-1(Human)
Constellation, A Morphosys

Curated by ChEMBL
LigandPNGBDBM50591367(CHEMBL5195542 | US20240190828, Compound 21)
Affinity DataIC50: 860nMAssay Description:Inhibition of biotinylated histone H3K14 (1 to 20 residues) peptide binding to His6-tagged recombinant human PBRM1 BD2 transfected in Escherichia col...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetProtein polybromo-1(Human)
Constellation, A Morphosys

Curated by ChEMBL
LigandPNGBDBM50591364(CHEMBL5194300 | US20240190828, Compound 17)
Affinity DataIC50: 870nMAssay Description:Inhibition of biotinylated histone H3K14 (1 to 20 residues) peptide binding to His6-tagged recombinant human PBRM1 BD2 transfected in Escherichia col...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetProtein polybromo-1(Human)
Constellation, A Morphosys

Curated by ChEMBL
LigandPNGBDBM50256397(CHEMBL4088466)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human PBRM1 bromodomain 5 (S645 to D766 residues) expressed in bacterial expression system by BROMOscan assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetProtein polybromo-1(Human)
Constellation, A Morphosys

Curated by ChEMBL
LigandPNGBDBM342597(N-[3-(3-methyl-4-oxo-4,5,6,7-tetrahydro-2H-isoindo...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human PBRM1 bromodomain 5 (S645 to D766 residues) expressed in bacterial expression system by BROMOscan assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetProtein polybromo-1(Human)
Constellation, A Morphosys

Curated by ChEMBL
LigandPNGBDBM50591358(CHEMBL5204703 | US20240190828, Compound 11)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of biotinylated histone H3K14 (1 to 20 residues) peptide binding to His6-tagged recombinant human PBRM1 BD2 transfected in Escherichia col...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetProtein polybromo-1(Human)
Constellation, A Morphosys

Curated by ChEMBL
LigandPNGBDBM50591359(CHEMBL5170175 | US20240190828, Compound 12)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of biotinylated histone H3K14 (1 to 20 residues) peptide binding to His6-tagged recombinant human PBRM1 BD2 transfected in Escherichia col...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetProtein polybromo-1(Human)
Constellation, A Morphosys

Curated by ChEMBL
LigandPNGBDBM50591379(CHEMBL5176658 | US20240190828, Compound 33)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of biotinylated histone H3K14 (1 to 20 residues) peptide binding to His6-tagged recombinant human PBRM1 BD2 transfected in Escherichia col...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetProtein polybromo-1(Human)
Constellation, A Morphosys

Curated by ChEMBL
LigandPNGBDBM50591368(CHEMBL5181215 | US20240190828, Compound 22)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of biotinylated histone H3K14 (1 to 20 residues) peptide binding to His6-tagged recombinant human PBRM1 BD2 transfected in Escherichia col...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetProtein polybromo-1(Human)
Constellation, A Morphosys

Curated by ChEMBL
LigandPNGBDBM50591360(CHEMBL5205087 | US20240190828, Compound 13)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of biotinylated histone H3K14 (1 to 20 residues) peptide binding to His6-tagged recombinant human PBRM1 BD2 transfected in Escherichia col...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetProtein polybromo-1(Human)
Constellation, A Morphosys

Curated by ChEMBL
LigandPNGBDBM50591361(CHEMBL5197320 | US20240190828, Compound 14)
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of biotinylated histone H3K14 (1 to 20 residues) peptide binding to His6-tagged recombinant human PBRM1 BD2 transfected in Escherichia col...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetProtein polybromo-1(Human)
Constellation, A Morphosys

Curated by ChEMBL
LigandPNGBDBM50591365(CHEMBL5171156 | US20240190828, Compound 18)
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of biotinylated histone H3K14 (1 to 20 residues) peptide binding to His6-tagged recombinant human PBRM1 BD2 transfected in Escherichia col...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetProtein polybromo-1(Human)
Constellation, A Morphosys

Curated by ChEMBL
LigandPNGBDBM50598934(CHEMBL5183240)
Affinity DataIC50: 3.10E+3nMAssay Description:Inhibition of PBRM1 bromodomain 5 (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails
PubMed
TargetProtein polybromo-1(Human)
Constellation, A Morphosys

Curated by ChEMBL
LigandPNGBDBM50591366(CHEMBL5203878 | US20240190828, Compound 20)
Affinity DataIC50: 5.60E+3nMAssay Description:Inhibition of biotinylated histone H3K14 (1 to 20 residues) peptide binding to His6-tagged recombinant human PBRM1 BD2 transfected in Escherichia col...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetProtein polybromo-1(Human)
Constellation, A Morphosys

Curated by ChEMBL
LigandPNGBDBM50591378(CHEMBL5178860 | US20240190828, Compound 32)
Affinity DataIC50: 5.60E+3nMAssay Description:Inhibition of biotinylated histone H3K14 (1 to 20 residues) peptide binding to His6-tagged recombinant human PBRM1 BD2 transfected in Escherichia col...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetProtein polybromo-1(Human)
Constellation, A Morphosys

Curated by ChEMBL
LigandPNGBDBM50591357(CHEMBL5205514 | US20240190828, Compound 8)
Affinity DataIC50: 6.30E+3nMAssay Description:Inhibition of biotinylated histone H3K14 (1 to 20 residues) peptide binding to His6-tagged recombinant human PBRM1 BD2 transfected in Escherichia col...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetProtein polybromo-1(Human)
Constellation, A Morphosys

Curated by ChEMBL
LigandPNGBDBM50591383(CHEMBL5184333 | US20240190828, Compound 36)
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibition of biotinylated histone H3K14 (1 to 20 residues) peptide binding to His6-tagged recombinant human PBRM1 BD2 transfected in Escherichia col...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetProtein polybromo-1(Human)
Constellation, A Morphosys

Curated by ChEMBL
LigandPNGBDBM310898(US10150767, Example 22 | N,N-dimethyl-3-(6-methyl-...)
Affinity DataIC50: 7.60E+3nMAssay Description:Binding affinity to human partial length PBRM1(2) expressed in bacterial expression system by BROMOscan assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails Article
PubMed
TargetProtein polybromo-1(Human)
Constellation, A Morphosys

Curated by ChEMBL
LigandPNGBDBM310898(US10150767, Example 22 | N,N-dimethyl-3-(6-methyl-...)
Affinity DataIC50: 7.60E+3nMAssay Description:Binding affinity to human partial length PBRM1(2) expressed in bacterial expression system by BROMOscan assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails Article
PubMed
TargetProtein polybromo-1(Human)
Constellation, A Morphosys

Curated by ChEMBL
LigandPNGBDBM342597(N-[3-(3-methyl-4-oxo-4,5,6,7-tetrahydro-2H-isoindo...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human PBRM1 bromodomain 2 (S178 to E291 residues) expressed in bacterial expression system by BROMOscan assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetProtein polybromo-1(Human)
Constellation, A Morphosys

Curated by ChEMBL
LigandPNGBDBM50158624(CHEMBL3786012)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human PBRM1 bromodomain 2 (S178 to E291 residues) expressed in bacterial expression system by BROMOscan assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein polybromo-1(Human)
Constellation, A Morphosys

Curated by ChEMBL
LigandPNGBDBM50256397(CHEMBL4088466)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human PBRM1 bromodomain 2 (S178 to E291 residues) expressed in bacterial expression system by BROMOscan assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetProtein polybromo-1(Human)
Constellation, A Morphosys

Curated by ChEMBL
LigandPNGBDBM50591374(CHEMBL5172472 | US20240190828, Compound 28)
Affinity DataIC50: 1.70E+4nMAssay Description:Inhibition of biotinylated histone H3K14 (1 to 20 residues) peptide binding to His6-tagged recombinant human PBRM1 BD2 transfected in Escherichia col...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetProtein polybromo-1(Human)
Constellation, A Morphosys

Curated by ChEMBL
LigandPNGBDBM50591382(CHEMBL5171944 | US20240190828, Compound 35)
Affinity DataIC50: 2.60E+4nMAssay Description:Inhibition of biotinylated histone H3K14 (1 to 20 residues) peptide binding to His6-tagged recombinant human PBRM1 BD2 transfected in Escherichia col...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetProtein polybromo-1(Human)
Constellation, A Morphosys

Curated by ChEMBL
LigandPNGBDBM50028142(CHEMBL2177300)
Affinity DataIC50: 3.16E+4nMAssay Description:Inhibition of human PBRM1 bromodomain 5 by BROMOscan assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein polybromo-1(Human)
Constellation, A Morphosys

Curated by ChEMBL
LigandPNGBDBM50104297(CHEMBL3594130 | US20240190828, Compound 19)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of biotinylated histone H3K14 (1 to 20 residues) peptide binding to His6-tagged recombinant human PBRM1 BD2 transfected in Escherichia col...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetProtein polybromo-1(Human)
Constellation, A Morphosys

Curated by ChEMBL
LigandPNGBDBM50591369(CHEMBL5186537 | US20240190828, Compound 23)
Affinity DataIC50: 7.00E+4nMAssay Description:Inhibition of biotinylated histone H3K14 (1 to 20 residues) peptide binding to His6-tagged recombinant human PBRM1 BD2 transfected in Escherichia col...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetProtein polybromo-1(Human)
Constellation, A Morphosys

Curated by ChEMBL
LigandPNGBDBM50591377(CHEMBL5200761 | US20240190828, Compound 31)
Affinity DataIC50: 7.00E+4nMAssay Description:Inhibition of biotinylated histone H3K14 (1 to 20 residues) peptide binding to His6-tagged recombinant human PBRM1 BD2 transfected in Escherichia col...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetProtein polybromo-1(Human)
Constellation, A Morphosys

Curated by ChEMBL
LigandPNGBDBM50591376(CHEMBL5196748 | US20240190828, Compound 30)
Affinity DataIC50: 8.99E+4nMAssay Description:Inhibition of biotinylated histone H3K14 (1 to 20 residues) peptide binding to His6-tagged recombinant human PBRM1 BD2 transfected in Escherichia col...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetProtein polybromo-1(Human)
Constellation, A Morphosys

Curated by ChEMBL
LigandPNGBDBM50495432(CHEMBL3108806)
Affinity DataIC50: 1.00E+5nMAssay Description:Displacement of H3K14(Ac) peptide from PB1-5 bromodomain (unknown origin) by AlphaScreen assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein polybromo-1(Human)
Constellation, A Morphosys

Curated by ChEMBL
LigandPNGBDBM50495427(CHEMBL1513201)
Affinity DataIC50: 1.00E+5nMAssay Description:Displacement of H3K14(Ac) peptide from PB1-5 bromodomain (unknown origin) by AlphaScreen assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein polybromo-1(Human)
Constellation, A Morphosys

Curated by ChEMBL
LigandPNGBDBM50495428(CHEMBL3110357)
Affinity DataIC50: 1.00E+5nMAssay Description:Displacement of H3K14(Ac) peptide from PB1-5 bromodomain (unknown origin) by AlphaScreen assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein polybromo-1(Human)
Constellation, A Morphosys

Curated by ChEMBL
LigandPNGBDBM50495429(CHEMBL3108781)
Affinity DataIC50: 1.00E+5nMAssay Description:Displacement of H3K14(Ac) peptide from PB1-5 bromodomain (unknown origin) by AlphaScreen assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein polybromo-1(Human)
Constellation, A Morphosys

Curated by ChEMBL
LigandPNGBDBM50591373(CHEMBL5171878 | US20240190828, Compound 27)
Affinity DataIC50: 1.19E+5nMAssay Description:Inhibition of biotinylated histone H3K14 (1 to 20 residues) peptide binding to His6-tagged recombinant human PBRM1 BD2 transfected in Escherichia col...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetProtein polybromo-1(Human)
Constellation, A Morphosys

Curated by ChEMBL
LigandPNGBDBM50591347(CHEMBL541514 | US20240190828, Compound 6)
Affinity DataIC50: 1.27E+5nMAssay Description:Inhibition of biotinylated histone H3K14 (1 to 20 residues) peptide binding to His6-tagged recombinant human PBRM1 BD2 transfected in Escherichia col...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetProtein polybromo-1(Human)
Constellation, A Morphosys

Curated by ChEMBL
LigandPNGBDBM50591375(CHEMBL5202589 | US20240190828, Compound 29)
Affinity DataIC50: 2.36E+5nMAssay Description:Inhibition of biotinylated histone H3K14 (1 to 20 residues) peptide binding to His6-tagged recombinant human PBRM1 BD2 transfected in Escherichia col...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetProtein polybromo-1(Human)
Constellation, A Morphosys

Curated by ChEMBL
LigandPNGBDBM50591384(Lobenzarit | LOBENZARIT | US20240190828, Compound ...)
Affinity DataIC50: 2.50E+5nMAssay Description:Inhibition of biotinylated histone H3K14 (1 to 20 residues) peptide binding to His6-tagged recombinant human PBRM1 BD2 transfected in Escherichia col...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetProtein polybromo-1(Human)
Constellation, A Morphosys

Curated by ChEMBL
LigandPNGBDBM50591385(CHEMBL5169618 | US20240190828, Compound 38)
Affinity DataIC50: 2.50E+5nMAssay Description:Inhibition of biotinylated histone H3K14 (1 to 20 residues) peptide binding to His6-tagged recombinant human PBRM1 BD2 transfected in Escherichia col...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed