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TargetUbiquitin carboxyl-terminal hydrolase 2(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50608544(CHEMBL3392741)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of human USP2 using Di-Ub IQF as substrate incubated for 15 mins by K63-2 assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetUbiquitin carboxyl-terminal hydrolase 2(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50458422(CHEMBL4216958)
Affinity DataIC50: 3.30E+3nMAssay Description:Inhibition of human USP2a (258 to 605 residues) expressed in Escherichia coli BL21(DE3) using Ub-AMC as substrate incubated for 30 mins measured at 3...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetUbiquitin carboxyl-terminal hydrolase 2(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50591324(CHEMBL5185273)
Affinity DataIC50: 3.80E+3nMAssay Description:Inhibition of USP2 (unknown origin) using Ub-Rho measured after 0.5 to 3 hrsMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetUbiquitin carboxyl-terminal hydrolase 2(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50591321(CHEMBL5172138)
Affinity DataIC50: 5.10E+3nMAssay Description:Inhibition of USP2 (unknown origin) using Ub-Rho measured after 0.5 to 3 hrsMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetUbiquitin carboxyl-terminal hydrolase 2(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50591322(CHEMBL5196686)
Affinity DataIC50: 6.20E+3nMAssay Description:Inhibition of USP2 (unknown origin) using Ub-Rho measured after 0.5 to 3 hrsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetUbiquitin carboxyl-terminal hydrolase 2(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50458415(CHEMBL567508 | EN300-02284)
Affinity DataIC50: 8.70E+3nMAssay Description:Inhibition of human USP2a (258 to 605 residues) expressed in Escherichia coli BL21(DE3) using Ub-AMC as substrate incubated for 30 mins measured at 3...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetUbiquitin carboxyl-terminal hydrolase 2(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50514116(CHEMBL4458718)
Affinity DataIC50: 9.70E+3nMAssay Description:Inhibition of USP2 (unknown origin) using Ub-AMC substrateMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetUbiquitin carboxyl-terminal hydrolase 2(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50538571(CHEMBL4635160)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human GST-tagged USP2 isoform 4 expressed in Escherichia coli assessed as cleavage of Ubiquitin-Rhodamine110-glycine to Ubiquitin and R...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetUbiquitin carboxyl-terminal hydrolase 2(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50591323(CHEMBL5173239)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of USP2 (unknown origin) using Ub-Rho measured after 0.5 to 3 hrsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetUbiquitin carboxyl-terminal hydrolase 2(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50442907(CHEMBL3039433 | Acetyl Isogambogic Acid)
Affinity DataIC50: 1.82E+4nMpH: 7.5 T: 2°CAssay Description:Ubiquitin-7-amino-4-methylcoumarin (Ub-AMC) was generated as previously described.(7) The enzymatic reaction was conducted in fluorometric assay buff...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetUbiquitin carboxyl-terminal hydrolase 2(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM200235(Rifampicin | cid_5381226)
Affinity DataIC50: 2.12E+4nMpH: 7.5 T: 2°CAssay Description:Ubiquitin-7-amino-4-methylcoumarin (Ub-AMC) was generated as previously described.(7) The enzymatic reaction was conducted in fluorometric assay buff...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetUbiquitin carboxyl-terminal hydrolase 2(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM217379(CDDO-Me, 2)
Affinity DataIC50: 2.20E+4nMAssay Description:Inhibition of USP2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetUbiquitin carboxyl-terminal hydrolase 2(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50612971(CHEMBL5273043)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of human His-tagged USP2 (259 to 605 residues) using ubiquitin rhodamine 110 110 as substrate preincubated for 15 to 20 mins followed by e...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetUbiquitin carboxyl-terminal hydrolase 2(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50612980(CHEMBL5275910)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of human His-tagged USP2 (259 to 605 residues) using ubiquitin rhodamine 110 110 as substrate preincubated for 15 to 20 mins followed by e...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetUbiquitin carboxyl-terminal hydrolase 2(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50612979(CHEMBL5274527)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of human His-tagged USP2 (259 to 605 residues) using ubiquitin rhodamine 110 110 as substrate preincubated for 15 to 20 mins followed by e...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetUbiquitin carboxyl-terminal hydrolase 2(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50612978(CHEMBL5269199)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of human His-tagged USP2 (259 to 605 residues) using ubiquitin rhodamine 110 110 as substrate preincubated for 15 to 20 mins followed by e...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetUbiquitin carboxyl-terminal hydrolase 2(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50612977(CHEMBL5278034)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of human His-tagged USP2 (259 to 605 residues) using ubiquitin rhodamine 110 110 as substrate preincubated for 15 to 20 mins followed by e...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetUbiquitin carboxyl-terminal hydrolase 2(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50612972(CHEMBL5271797)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of human His-tagged USP2 (259 to 605 residues) using ubiquitin rhodamine 110 110 as substrate preincubated for 15 to 20 mins followed by e...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetUbiquitin carboxyl-terminal hydrolase 2(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50612973(CHEMBL5266408)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of human His-tagged USP2 (259 to 605 residues) using ubiquitin rhodamine 110 110 as substrate preincubated for 15 to 20 mins followed by e...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetUbiquitin carboxyl-terminal hydrolase 2(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50612981(CHEMBL5275560)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of human His-tagged USP2 (259 to 605 residues) using ubiquitin rhodamine 110 110 as substrate preincubated for 15 to 20 mins followed by e...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetUbiquitin carboxyl-terminal hydrolase 2(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50612974(CHEMBL5269090)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of human His-tagged USP2 (259 to 605 residues) using ubiquitin rhodamine 110 110 as substrate preincubated for 15 to 20 mins followed by e...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetUbiquitin carboxyl-terminal hydrolase 2(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50612975(CHEMBL5269490)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of human His-tagged USP2 (259 to 605 residues) using ubiquitin rhodamine 110 110 as substrate preincubated for 15 to 20 mins followed by e...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetUbiquitin carboxyl-terminal hydrolase 2(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50612976(CHEMBL5266959)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of human His-tagged USP2 (259 to 605 residues) using ubiquitin rhodamine 110 110 as substrate preincubated for 15 to 20 mins followed by e...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetUbiquitin carboxyl-terminal hydrolase 2(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM205457(Celastrol | (2R,4aS,6aR,6aS,14aS,14bR)-10-hydroxy-...)
Affinity DataIC50: 2.87E+4nMpH: 7.5 T: 2°CAssay Description:Ubiquitin-7-amino-4-methylcoumarin (Ub-AMC) was generated as previously described.(7) The enzymatic reaction was conducted in fluorometric assay buff...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetUbiquitin carboxyl-terminal hydrolase 2(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50436152(SPONGIACIDIN C)
Affinity DataIC50: 3.16E+4nMAssay Description:Inhibition of core catalytic domain of USP2 (unknown origin) using diubiquitin IQF K4804 as substrateMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetUbiquitin carboxyl-terminal hydrolase 2(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50072959(CHEMBL3410535)
Affinity DataIC50: 3.26E+4nMAssay Description:Inhibition of USP2 catalytic domain (unknown origin) expressed in bacteria using Ub-AMC as substrate preincubated for 30 mins before substrate additi...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetUbiquitin carboxyl-terminal hydrolase 2(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50200099(CHEMBL727 | 6-thioguanine | 2-Amino-9H-purine-6-th...)
Affinity DataIC50: 4.20E+4nMAssay Description:Inhibition of human USP2 (258 to 605 residues) catalytic domain by fluorescence based assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetUbiquitin carboxyl-terminal hydrolase 2(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50597468(CHEMBL5184337)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of USP2 (267 to 599 residues) (unknown origin) catalytic domain expressed in Escherichia coli BL21 (DE3) cells using ubiquitin-rhodamine -...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetUbiquitin carboxyl-terminal hydrolase 2(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50458419(CHEMBL4203286)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human USP2a (258 to 605 residues) expressed in Escherichia coli BL21(DE3) using Ub-AMC as substrate incubated for 30 mins measured at 3...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetUbiquitin carboxyl-terminal hydrolase 2(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50269827(CHEMBL4089822)
Affinity DataIC50: 6.61E+4nMAssay Description:Inhibition of recombinant human N-terminal His-tagged USP2 catalytic domain (258 to 605 residues) expressed in Escherichia coli BL21(DE3) using human...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetUbiquitin carboxyl-terminal hydrolase 2(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50242207(Mangiferin | CHEMBL455364)
Affinity DataIC50: 6.78E+4nMpH: 7.5 T: 2°CAssay Description:Ubiquitin-7-amino-4-methylcoumarin (Ub-AMC) was generated as previously described.(7) The enzymatic reaction was conducted in fluorometric assay buff...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetUbiquitin carboxyl-terminal hydrolase 2(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50458417(CHEMBL4203489)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human USP2a (258 to 605 residues) expressed in Escherichia coli BL21(DE3) using Ub-AMC as substrate incubated for 30 mins measured at 3...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetUbiquitin carboxyl-terminal hydrolase 2(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50007788(CHEMBL3233809 | med.21724, Compound 167)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human USP2 using Ub-rhodamine 110 as substrateMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetUbiquitin carboxyl-terminal hydrolase 2(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50423778(Mercaptopurine anhydrous | Leukerin | Mercaleukin ...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human USP2 (258 to 605 residues) catalytic domain by fluorescence based assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetUbiquitin carboxyl-terminal hydrolase 2(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50069762(CHEMBL3182437 | ML323 | US9802904, 87)
Affinity DataIC50: 1.14E+5nMpH: 7.5 T: 2°CAssay Description:Ubiquitin-7-amino-4-methylcoumarin (Ub-AMC) was generated as previously described.(7) The enzymatic reaction was conducted in fluorometric assay buff...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetUbiquitin carboxyl-terminal hydrolase 2(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM65524((-)-Aricine | Heterophylline (VAN) | Quinovatine)
Affinity DataIC50: 1.14E+5nMpH: 7.5 T: 2°CAssay Description:Ubiquitin-7-amino-4-methylcoumarin (Ub-AMC) was generated as previously described.(7) The enzymatic reaction was conducted in fluorometric assay buff...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetUbiquitin carboxyl-terminal hydrolase 2(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50608424(CHEMBL5267683)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of human his tagged USP2 by Westernblot analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetUbiquitin carboxyl-terminal hydrolase 2(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50458418(CHEMBL4207578)
Affinity DataIC50: 5.00E+6nMAssay Description:Inhibition of human USP2a (258 to 605 residues) expressed in Escherichia coli BL21(DE3) using Ub-AMC as substrate incubated for 30 mins measured at 3...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetUbiquitin carboxyl-terminal hydrolase 2(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50458420(CHEMBL4207620)
Affinity DataIC50: 5.00E+6nMAssay Description:Inhibition of human USP2a (258 to 605 residues) expressed in Escherichia coli BL21(DE3) using Ub-AMC as substrate incubated for 30 mins measured at 3...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetUbiquitin carboxyl-terminal hydrolase 2(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50458421(CHEMBL1650269)
Affinity DataIC50: 5.00E+6nMAssay Description:Inhibition of human USP2a (258 to 605 residues) expressed in Escherichia coli BL21(DE3) using Ub-AMC as substrate incubated for 30 mins measured at 3...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetUbiquitin carboxyl-terminal hydrolase 2(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50458416(CHEMBL1230155)
Affinity DataIC50: 1.30E+6nMAssay Description:Inhibition of human USP2a (258 to 605 residues) expressed in Escherichia coli BL21(DE3) using Ub-AMC as substrate incubated for 30 mins measured at 3...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed