Compile Data Set for Download or QSAR
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TargetUbiquitin carboxyl-terminal hydrolase 8(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50591324(CHEMBL5185273)
Affinity DataIC50: 0.280nMAssay Description:Inhibition of N-terminal His-6 tagged USP8 (734 to 1110 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3) cells measured after 3 hr...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetUbiquitin carboxyl-terminal hydrolase 8(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50591322(CHEMBL5196686)
Affinity DataIC50: 1.30nMAssay Description:Inhibition of N-terminal His-6 tagged USP8 (734 to 1110 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3) cells measured after 3 hr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetUbiquitin carboxyl-terminal hydrolase 8(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50591323(CHEMBL5173239)
Affinity DataIC50: 2nMAssay Description:Inhibition of N-terminal His-6 tagged USP8 (734 to 1110 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3) cells measured after 3 hr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetUbiquitin carboxyl-terminal hydrolase 8(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50591321(CHEMBL5172138)
Affinity DataIC50: 2.70nMAssay Description:Inhibition of N-terminal His-6 tagged USP8 (734 to 1110 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3) cells measured after 3 hr...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetUbiquitin carboxyl-terminal hydrolase 8(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50436151(CHEMBL2398212)
Affinity DataIC50: 96nMAssay Description:Inhibition of human full-length His-tagged USP8 expressed baculovirus infected insect cells using Ub-AMC as substrate by fluorescence spectroscopic a...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetUbiquitin carboxyl-terminal hydrolase 8(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50436151(CHEMBL2398212)
Affinity DataIC50: 96nMAssay Description:Inhibition of human USP8 using Ub-AMC as substrateMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetUbiquitin carboxyl-terminal hydrolase 8(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50069768(CHEMBL3407548)
Affinity DataIC50: 133nMAssay Description:Inhibition of human USP8 using Ub-AMC as substrateMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetUbiquitin carboxyl-terminal hydrolase 8(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50608392(CHEMBL5281075)
Affinity DataIC50: 250nMAssay Description:Inhibition of human USP8 using Ub-AMC as substrateMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetUbiquitin carboxyl-terminal hydrolase 8(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50608392(CHEMBL5281075)
Affinity DataIC50: 250nMAssay Description:Inhibition of USP8 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetUbiquitin carboxyl-terminal hydrolase 8(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50597448(CHEMBL5180195)
Affinity DataIC50: 280nMAssay Description:Inhibition of human full length USP8 overexpressed in baculovirus-infected insect cells using ubiquitin-C-terminal 7-amido-4-methylcoumarin as substr...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetUbiquitin carboxyl-terminal hydrolase 8(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50608385(CHEMBL4569978)
Affinity DataIC50: 290nMAssay Description:Inhibition of human USP8 using Ub-AMC as substrateMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetUbiquitin carboxyl-terminal hydrolase 8(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50597449(CHEMBL5170305)
Affinity DataIC50: 290nMAssay Description:Inhibition of human full length USP8 overexpressed in baculovirus-infected insect cells using ubiquitin-C-terminal 7-amido-4-methylcoumarin as substr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetUbiquitin carboxyl-terminal hydrolase 8(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50608385(CHEMBL4569978)
Affinity DataIC50: 290nMAssay Description:Inhibition of USP8 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetUbiquitin carboxyl-terminal hydrolase 8(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50608394(CHEMBL5269711)
Affinity DataIC50: 316nMAssay Description:Inhibition of human USP8 using Ub-AMC as substrateMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetUbiquitin carboxyl-terminal hydrolase 8(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50597451(CHEMBL5202404)
Affinity DataIC50: 560nMAssay Description:Inhibition of human full length USP8 overexpressed in baculovirus-infected insect cells using ubiquitin-C-terminal 7-amido-4-methylcoumarin as substr...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetUbiquitin carboxyl-terminal hydrolase 8(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50608389(CHEMBL5276040)
Affinity DataIC50: 710nMAssay Description:Inhibition of human USP8 using Ub-AMC as substrateMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetUbiquitin carboxyl-terminal hydrolase 8(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50608391(CHEMBL4515695)
Affinity DataIC50: 810nMAssay Description:Inhibition of human USP8 using Ub-AMC as substrateMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetUbiquitin carboxyl-terminal hydrolase 8(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50597450(CHEMBL5208383)
Affinity DataIC50: 850nMAssay Description:Inhibition of human full length USP8 overexpressed in baculovirus-infected insect cells using ubiquitin-C-terminal 7-amido-4-methylcoumarin as substr...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetUbiquitin carboxyl-terminal hydrolase 8(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50608390(CHEMBL4584162)
Affinity DataIC50: 930nMAssay Description:Inhibition of human USP8 using Ub-AMC as substrateMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetUbiquitin carboxyl-terminal hydrolase 8(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50608544(CHEMBL3392741)
Affinity DataIC50: 950nMAssay Description:Inhibition of human USP8 using Di-Ub IQF as substrate incubated for 15 mins by K63-2 assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetUbiquitin carboxyl-terminal hydrolase 8(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50436151(CHEMBL2398212)
Affinity DataIC50: 960nMAssay Description:Inhibition of USP8 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetUbiquitin carboxyl-terminal hydrolase 8(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50597468(CHEMBL5184337)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of N-terminal His6-tagged USP8 (unknown origin) catalytic domain (734 to 1110 residues) expressed in Escherichia coli BL21 (DE3) cells ass...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetUbiquitin carboxyl-terminal hydrolase 8(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50597448(CHEMBL5180195)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of N-terminal His6-tagged USP8 (unknown origin) catalytic domain (734 to 1110 residues) expressed in Escherichia coli BL21 (DE3) cells ass...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetUbiquitin carboxyl-terminal hydrolase 8(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50608393(CHEMBL4580655)
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of human USP8 using Ub-AMC as substrateMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetUbiquitin carboxyl-terminal hydrolase 8(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50597463(CHEMBL5176518)
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of N-terminal His6-tagged USP8 (unknown origin) catalytic domain (734 to 1110 residues) expressed in Escherichia coli BL21 (DE3) cells ass...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetUbiquitin carboxyl-terminal hydrolase 8(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50608387(CHEMBL4550273)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of human USP8 using Ub-AMC as substrateMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetUbiquitin carboxyl-terminal hydrolase 8(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50597452(CHEMBL5171659)
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibition of N-terminal His6-tagged USP8 (unknown origin) expressed in Escherichia coli BL21 (DE3) cells using ubiquitin-rhodamine -110 as substrate...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetUbiquitin carboxyl-terminal hydrolase 8(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50608388(CHEMBL5272836)
Affinity DataIC50: 3.10E+3nMAssay Description:Inhibition of human USP8 using Ub-AMC as substrateMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetUbiquitin carboxyl-terminal hydrolase 8(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50597469(CHEMBL5197403)
Affinity DataIC50: 3.50E+3nMAssay Description:Inhibition of N-terminal His6-tagged USP8 (unknown origin) catalytic domain (734 to 1110 residues) expressed in Escherichia coli BL21 (DE3) cells ass...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetUbiquitin carboxyl-terminal hydrolase 8(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50608386(CHEMBL4442330)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of human USP8 using Ub-AMC as substrateMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetUbiquitin carboxyl-terminal hydrolase 8(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50597467(CHEMBL5206972)
Affinity DataIC50: 5.10E+3nMAssay Description:Inhibition of N-terminal His6-tagged USP8 (unknown origin) catalytic domain (734 to 1110 residues) expressed in Escherichia coli BL21 (DE3) cells ass...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetUbiquitin carboxyl-terminal hydrolase 8(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50608395(CHEMBL5282532)
Affinity DataIC50: 8.40E+3nMAssay Description:Inhibition of human USP8 using Ub-AMC as substrateMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetUbiquitin carboxyl-terminal hydrolase 8(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50538571(CHEMBL4635160)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human USP8 expressed in Escherichia coli assessed as cleavage of Ubiquitin-Rhodamine110-glycine to Ubiquitin and Rhodamine110-glycine u...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetUbiquitin carboxyl-terminal hydrolase 8(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50548233(CHEMBL4756029)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of USP8 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetUbiquitin carboxyl-terminal hydrolase 8(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50608384(CHEMBL5276519)
Affinity DataIC50: 1.30E+4nMAssay Description:Inhibition of USP8 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetUbiquitin carboxyl-terminal hydrolase 8(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50608384(CHEMBL5276519)
Affinity DataIC50: 1.30E+4nMAssay Description:Inhibition of human USP8 using Ub-AMC as substrateMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetUbiquitin carboxyl-terminal hydrolase 8(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50597465(CHEMBL5205340)
Affinity DataIC50: 1.55E+4nMAssay Description:Inhibition of N-terminal His6-tagged USP8 (unknown origin) catalytic domain (734 to 1110 residues) expressed in Escherichia coli BL21 (DE3) cells ass...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetUbiquitin carboxyl-terminal hydrolase 8(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50597455(CHEMBL5206674)
Affinity DataIC50: 1.62E+4nMAssay Description:Inhibition of N-terminal His6-tagged USP8 (unknown origin) catalytic domain (734 to 1110 residues) expressed in Escherichia coli BL21 (DE3) cells ass...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetUbiquitin carboxyl-terminal hydrolase 8(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50597457(CHEMBL4469440)
Affinity DataIC50: 1.62E+4nMAssay Description:Inhibition of N-terminal His6-tagged USP8 (unknown origin) catalytic domain (734 to 1110 residues) expressed in Escherichia coli BL21 (DE3) cells ass...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetUbiquitin carboxyl-terminal hydrolase 8(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50597464(CHEMBL5181521)
Affinity DataIC50: 1.63E+4nMAssay Description:Inhibition of N-terminal His6-tagged USP8 (unknown origin) catalytic domain (734 to 1110 residues) expressed in Escherichia coli BL21 (DE3) cells ass...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetUbiquitin carboxyl-terminal hydrolase 8(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50597462(CHEMBL4536844)
Affinity DataIC50: 1.65E+4nMAssay Description:Inhibition of N-terminal His6-tagged USP8 (unknown origin) catalytic domain (734 to 1110 residues) expressed in Escherichia coli BL21 (DE3) cells ass...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetUbiquitin carboxyl-terminal hydrolase 8(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50597456(CHEMBL5198716)
Affinity DataIC50: 1.76E+4nMAssay Description:Inhibition of N-terminal His6-tagged USP8 (unknown origin) catalytic domain (734 to 1110 residues) expressed in Escherichia coli BL21 (DE3) cells ass...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetUbiquitin carboxyl-terminal hydrolase 8(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50597458(CHEMBL4591454)
Affinity DataIC50: 1.83E+4nMAssay Description:Inhibition of N-terminal His6-tagged USP8 (unknown origin) catalytic domain (734 to 1110 residues) expressed in Escherichia coli BL21 (DE3) cells ass...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetUbiquitin carboxyl-terminal hydrolase 8(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50597466(CHEMBL5170419)
Affinity DataIC50: 2.35E+4nMAssay Description:Inhibition of N-terminal His6-tagged USP8 (unknown origin) catalytic domain (734 to 1110 residues) expressed in Escherichia coli BL21 (DE3) cells ass...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetUbiquitin carboxyl-terminal hydrolase 8(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50597454(CHEMBL5175647)
Affinity DataIC50: 2.45E+4nMAssay Description:Inhibition of N-terminal His6-tagged USP8 (unknown origin) catalytic domain (734 to 1110 residues) expressed in Escherichia coli BL21 (DE3) cells ass...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetUbiquitin carboxyl-terminal hydrolase 8(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50608396(CHEMBL4438288)
Affinity DataIC50: 3.10E+4nMAssay Description:Inhibition of USP8 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetUbiquitin carboxyl-terminal hydrolase 8(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50608396(CHEMBL4438288)
Affinity DataIC50: 3.10E+4nMAssay Description:Inhibition of human USP8 using Ub-AMC as substrateMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetUbiquitin carboxyl-terminal hydrolase 8(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50597453(CHEMBL4567355)
Affinity DataIC50: 3.16E+4nMAssay Description:Inhibition of N-terminal His6-tagged USP8 (unknown origin) catalytic domain (734 to 1110 residues) expressed in Escherichia coli BL21 (DE3) cells ass...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetUbiquitin carboxyl-terminal hydrolase 8(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50436152(SPONGIACIDIN C)
Affinity DataIC50: 3.16E+4nMAssay Description:Inhibition of core catalytic domain of USP8 (unknown origin) using ubiquitin-Rh110 as substrateMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetUbiquitin carboxyl-terminal hydrolase 8(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50597459(CHEMBL5170083)
Affinity DataIC50: 3.60E+4nMAssay Description:Inhibition of N-terminal His6-tagged USP8 (unknown origin) catalytic domain (734 to 1110 residues) expressed in Escherichia coli BL21 (DE3) cells ass...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
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