Compile Data Set for Download or QSAR
Report error Found 72 of ic50 data for polymerid = 50004567
TargetReceptor tyrosine-protein kinase erbB-3(Human)
Wuxi Apptec

Curated by ChEMBL
LigandPNGBDBM50210162(CHEMBL3883534)
Affinity DataIC50: 1nMAssay Description:Inhibition of EGFR L858R mutant phosphorylation in human H3255 cells preincubated for 2 hrs followed by EGF stimulation for 10 mins by sandwich ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-3(Human)
Wuxi Apptec

Curated by ChEMBL
LigandPNGBDBM50461172(CHEMBL4228518)
Affinity DataIC50: 1.20nMAssay Description:Inhibition of EGFR L858R mutant (unknown origin) using poly (Glu, Tyr) as substrate after 40 mins by kinase-glo plus luminescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-3(Human)
Wuxi Apptec

Curated by ChEMBL
LigandPNGBDBM50461178(CHEMBL4225777)
Affinity DataIC50: 1.70nMAssay Description:Inhibition of EGFR L858R mutant (unknown origin) using poly (Glu, Tyr) as substrate after 40 mins by kinase-glo plus luminescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-3(Human)
Wuxi Apptec

Curated by ChEMBL
LigandPNGBDBM50461174(CHEMBL4226676)
Affinity DataIC50: 1.90nMAssay Description:Inhibition of EGFR L858R mutant (unknown origin) using poly (Glu, Tyr) as substrate after 40 mins by kinase-glo plus luminescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-3(Human)
Wuxi Apptec

Curated by ChEMBL
LigandPNGBDBM50461179(CHEMBL4226151)
Affinity DataIC50: 2nMAssay Description:Inhibition of EGFR L858R mutant (unknown origin) using poly (Glu, Tyr) as substrate after 40 mins by kinase-glo plus luminescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-3(Human)
Wuxi Apptec

Curated by ChEMBL
LigandPNGBDBM50112173(CHEMBL3608429)
Affinity DataIC50: 2nMAssay Description:Inhibition of EGFR L858R mutant phosphorylation in human H3255 cells preincubated for 2 hrs followed by EGF stimulation for 10 mins by sandwich ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-3(Human)
Wuxi Apptec

Curated by ChEMBL
LigandPNGBDBM50450868(CHEMBL4216679)
Affinity DataIC50: 2nMAssay Description:Inhibition of EGFR L858R mutant phosphorylation in human H3255 cells preincubated for 2 hrs followed by EGF stimulation for 10 mins by sandwich ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-3(Human)
Wuxi Apptec

Curated by ChEMBL
LigandPNGBDBM50029668(AZD-9291 | Osimertinib | US10085983, Compound AZD-...)
Affinity DataIC50: 2.10nMAssay Description:Inhibition of EGFR L858R mutant (unknown origin) using poly (Glu, Tyr) as substrate after 40 mins by kinase-glo plus luminescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-3(Human)
Wuxi Apptec

Curated by ChEMBL
LigandPNGBDBM50461175(CHEMBL4225565)
Affinity DataIC50: 2.40nMAssay Description:Inhibition of EGFR L858R mutant (unknown origin) using poly (Glu, Tyr) as substrate after 40 mins by kinase-glo plus luminescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-3(Human)
Wuxi Apptec

Curated by ChEMBL
LigandPNGBDBM50461176(CHEMBL4227084)
Affinity DataIC50: 2.60nMAssay Description:Inhibition of EGFR L858R mutant (unknown origin) using poly (Glu, Tyr) as substrate after 40 mins by kinase-glo plus luminescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-3(Human)
Wuxi Apptec

Curated by ChEMBL
LigandPNGBDBM50437353(CHEMBL2408045)
Affinity DataIC50: 4nMAssay Description:Inhibition of human HER3 expressed in baculovirus/Sf21 system by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-3(Human)
Wuxi Apptec

Curated by ChEMBL
LigandPNGBDBM50450870(Mavelertinib | PF-06747775)
Affinity DataIC50: 4nMAssay Description:Inhibition of EGFR L858R mutant phosphorylation in human H3255 cells preincubated for 2 hrs followed by EGF stimulation for 10 mins by sandwich ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-3(Human)
Wuxi Apptec

Curated by ChEMBL
LigandPNGBDBM50461177(CHEMBL4225951)
Affinity DataIC50: 4.20nMAssay Description:Inhibition of EGFR L858R mutant (unknown origin) using poly (Glu, Tyr) as substrate after 40 mins by kinase-glo plus luminescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-3(Human)
Wuxi Apptec

Curated by ChEMBL
LigandPNGBDBM50461180(CHEMBL4225306)
Affinity DataIC50: 4.20nMAssay Description:Inhibition of EGFR L858R mutant (unknown origin) using poly (Glu, Tyr) as substrate after 40 mins by kinase-glo plus luminescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-3(Human)
Wuxi Apptec

Curated by ChEMBL
LigandPNGBDBM50461173(CHEMBL4226937)
Affinity DataIC50: 5.80nMAssay Description:Inhibition of EGFR L858R mutant (unknown origin) using poly (Glu, Tyr) as substrate after 40 mins by kinase-glo plus luminescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-3(Human)
Wuxi Apptec

Curated by ChEMBL
LigandPNGBDBM50112176(CHEMBL3608432)
Affinity DataIC50: 9nMAssay Description:Inhibition of EGFR L858R mutant phosphorylation in human H3255 cells preincubated for 2 hrs followed by EGF stimulation for 10 mins by sandwich ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-3(Human)
Wuxi Apptec

Curated by ChEMBL
LigandPNGBDBM5446(Erlotinib | OSI-774 | N-(3-ethynylphenyl)-6,7-bis(...)
Affinity DataIC50: 10nMAssay Description:Inhibition of EGFR L858R mutant phosphorylation in human H3255 cells preincubated for 2 hrs followed by EGF stimulation for 10 mins by sandwich ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-3(Human)
Wuxi Apptec

Curated by ChEMBL
LigandPNGBDBM50467144(CHEMBL4288300)
Affinity DataIC50: 18nMAssay Description:Inhibition of recombinant human GST-tagged EGFR L858R mutant cytoplasmic domain expressed in baculovirus expression system using FAM-labeled peptide ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-3(Human)
Wuxi Apptec

Curated by ChEMBL
LigandPNGBDBM50159360(CHEMBL3786098)
Affinity DataIC50: 21nMAssay Description:Inhibition of EGFR L858R mutant phosphorylation in human H3255 cells preincubated for 2 hrs followed by EGF stimulation for 10 mins by sandwich ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-3(Human)
Wuxi Apptec

Curated by ChEMBL
LigandPNGBDBM50467162(CHEMBL4282460)
Affinity DataIC50: 21nMAssay Description:Inhibition of recombinant human GST-tagged EGFR L858R mutant cytoplasmic domain expressed in baculovirus expression system using FAM-labeled peptide ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-3(Human)
Wuxi Apptec

Curated by ChEMBL
LigandPNGBDBM50611358(CHEMBL5285282)
Affinity DataIC50: 23nMAssay Description:Inhibition of HER3 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetReceptor tyrosine-protein kinase erbB-3(Human)
Wuxi Apptec

Curated by ChEMBL
LigandPNGBDBM50467143(CHEMBL4283970)
Affinity DataIC50: 27nMAssay Description:Inhibition of recombinant human GST-tagged EGFR L858R mutant cytoplasmic domain expressed in baculovirus expression system using FAM-labeled peptide ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-3(Human)
Wuxi Apptec

Curated by ChEMBL
LigandPNGBDBM50467148(CHEMBL4294156)
Affinity DataIC50: 31nMAssay Description:Inhibition of recombinant human GST-tagged EGFR L858R mutant cytoplasmic domain expressed in baculovirus expression system using FAM-labeled peptide ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-3(Human)
Wuxi Apptec

Curated by ChEMBL
LigandPNGBDBM50450867(CHEMBL4206501)
Affinity DataIC50: 36nMAssay Description:Inhibition of EGFR L858R mutant phosphorylation in human H3255 cells preincubated for 2 hrs followed by EGF stimulation for 10 mins by sandwich ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-3(Human)
Wuxi Apptec

Curated by ChEMBL
LigandPNGBDBM149404(US8975249, I-4 | CO-1686 | Rociletinib | AVL-301 |...)
Affinity DataIC50: 46nMAssay Description:Inhibition of EGFR L858R mutant phosphorylation in human H3255 cells preincubated for 2 hrs followed by EGF stimulation for 10 mins by sandwich ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-3(Human)
Wuxi Apptec

Curated by ChEMBL
LigandPNGBDBM50618990(CHEMBL5399200)
Affinity DataIC50: 49nMAssay Description:Induction of N-terminal 6xHis-tagged GST-fused human Her3 degradation expressed in baculovirus infected insect cells measured after 3 hrs by FRET ana...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetReceptor tyrosine-protein kinase erbB-3(Human)
Wuxi Apptec

Curated by ChEMBL
LigandPNGBDBM50611359(CHEMBL5282275)
Affinity DataIC50: 49nMAssay Description:Inhibition of HER3 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetReceptor tyrosine-protein kinase erbB-3(Human)
Wuxi Apptec

Curated by ChEMBL
LigandPNGBDBM50467152(CHEMBL4283823)
Affinity DataIC50: 60nMAssay Description:Inhibition of recombinant human GST-tagged EGFR L858R mutant cytoplasmic domain expressed in baculovirus expression system using FAM-labeled peptide ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-3(Human)
Wuxi Apptec

Curated by ChEMBL
LigandPNGBDBM50467163(CHEMBL4290750)
Affinity DataIC50: 69nMAssay Description:Inhibition of recombinant human GST-tagged EGFR L858R mutant cytoplasmic domain expressed in baculovirus expression system using FAM-labeled peptide ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-3(Human)
Wuxi Apptec

Curated by ChEMBL
LigandPNGBDBM50467146(CHEMBL1379917)
Affinity DataIC50: 96nMAssay Description:Inhibition of recombinant human GST-tagged EGFR L858R mutant cytoplasmic domain expressed in baculovirus expression system using FAM-labeled peptide ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-3(Human)
Wuxi Apptec

Curated by ChEMBL
LigandPNGBDBM50467151(CHEMBL4293690)
Affinity DataIC50: 167nMAssay Description:Inhibition of recombinant human GST-tagged EGFR L858R mutant cytoplasmic domain expressed in baculovirus expression system using FAM-labeled peptide ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-3(Human)
Wuxi Apptec

Curated by ChEMBL
LigandPNGBDBM50467147(CHEMBL4283097)
Affinity DataIC50: 167nMAssay Description:Inhibition of recombinant human GST-tagged EGFR L858R mutant cytoplasmic domain expressed in baculovirus expression system using FAM-labeled peptide ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-3(Human)
Wuxi Apptec

Curated by ChEMBL
LigandPNGBDBM50467161(CHEMBL4278997)
Affinity DataIC50: 183nMAssay Description:Inhibition of recombinant human GST-tagged EGFR L858R mutant cytoplasmic domain expressed in baculovirus expression system using FAM-labeled peptide ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-3(Human)
Wuxi Apptec

Curated by ChEMBL
LigandPNGBDBM50467158(CHEMBL4280395)
Affinity DataIC50: 230nMAssay Description:Inhibition of recombinant human GST-tagged EGFR L858R mutant cytoplasmic domain expressed in baculovirus expression system using FAM-labeled peptide ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-3(Human)
Wuxi Apptec

Curated by ChEMBL
LigandPNGBDBM50467159(CHEMBL4288262)
Affinity DataIC50: 236nMAssay Description:Inhibition of recombinant human GST-tagged EGFR L858R mutant cytoplasmic domain expressed in baculovirus expression system using FAM-labeled peptide ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-3(Human)
Wuxi Apptec

Curated by ChEMBL
LigandPNGBDBM50467155(CHEMBL4276965)
Affinity DataIC50: 619nMAssay Description:Inhibition of recombinant human GST-tagged EGFR L858R mutant cytoplasmic domain expressed in baculovirus expression system using FAM-labeled peptide ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-3(Human)
Wuxi Apptec

Curated by ChEMBL
LigandPNGBDBM50467149(CHEMBL4287629)
Affinity DataIC50: 825nMAssay Description:Inhibition of recombinant human GST-tagged EGFR L858R mutant cytoplasmic domain expressed in baculovirus expression system using FAM-labeled peptide ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-3(Human)
Wuxi Apptec

Curated by ChEMBL
LigandPNGBDBM50467142(CHEMBL4293134)
Affinity DataIC50: 1.21E+3nMAssay Description:Inhibition of recombinant human GST-tagged EGFR L858R mutant cytoplasmic domain expressed in baculovirus expression system using FAM-labeled peptide ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-3(Human)
Wuxi Apptec

Curated by ChEMBL
LigandPNGBDBM50467153(CHEMBL4289682)
Affinity DataIC50: 1.32E+3nMAssay Description:Inhibition of recombinant human GST-tagged EGFR L858R mutant cytoplasmic domain expressed in baculovirus expression system using FAM-labeled peptide ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-3(Human)
Wuxi Apptec

Curated by ChEMBL
LigandPNGBDBM50467164(CHEMBL4288761)
Affinity DataIC50: 1.35E+3nMAssay Description:Inhibition of recombinant human GST-tagged EGFR L858R mutant cytoplasmic domain expressed in baculovirus expression system using FAM-labeled peptide ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-3(Human)
Wuxi Apptec

Curated by ChEMBL
LigandPNGBDBM50467166(CHEMBL4278031)
Affinity DataIC50: 1.57E+3nMAssay Description:Inhibition of recombinant human GST-tagged EGFR L858R mutant cytoplasmic domain expressed in baculovirus expression system using FAM-labeled peptide ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-3(Human)
Wuxi Apptec

Curated by ChEMBL
LigandPNGBDBM50467160(CHEMBL4281413)
Affinity DataIC50: 1.61E+3nMAssay Description:Inhibition of recombinant human GST-tagged EGFR L858R mutant cytoplasmic domain expressed in baculovirus expression system using FAM-labeled peptide ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-3(Human)
Wuxi Apptec

Curated by ChEMBL
LigandPNGBDBM50467157(CHEMBL4292110)
Affinity DataIC50: 1.75E+3nMAssay Description:Inhibition of recombinant human GST-tagged EGFR L858R mutant cytoplasmic domain expressed in baculovirus expression system using FAM-labeled peptide ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-3(Human)
Wuxi Apptec

Curated by ChEMBL
LigandPNGBDBM50467150(CHEMBL4284911)
Affinity DataIC50: 1.85E+3nMAssay Description:Inhibition of recombinant human GST-tagged EGFR L858R mutant cytoplasmic domain expressed in baculovirus expression system using FAM-labeled peptide ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-3(Human)
Wuxi Apptec

Curated by ChEMBL
LigandPNGBDBM494927(US10994015, Example 66 | (2S,4R)-1-((S)-2-(6-(4-(4...)
Affinity DataIC50: 6.60E+3nMAssay Description:All compounds and PROTACs were serially diluted in three-fold increments using 100% DMSO, followed by an intermediate 10-fold dilution using Buffer A...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails
US Patent

TargetReceptor tyrosine-protein kinase erbB-3(Human)
Wuxi Apptec

Curated by ChEMBL
LigandPNGBDBM494934(US10994015, Example 76 | 2-(2,6-dioxopiperidin-3-y...)
Affinity DataIC50: 8.60E+3nMAssay Description:All compounds and PROTACs were serially diluted in three-fold increments using 100% DMSO, followed by an intermediate 10-fold dilution using Buffer A...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetReceptor tyrosine-protein kinase erbB-3(Human)
Wuxi Apptec

Curated by ChEMBL
LigandPNGBDBM50467165(CHEMBL4283061)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant human GST-tagged EGFR L858R mutant cytoplasmic domain expressed in baculovirus expression system using FAM-labeled peptide ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-3(Human)
Wuxi Apptec

Curated by ChEMBL
LigandPNGBDBM50467156(CHEMBL4286871)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant human GST-tagged EGFR L858R mutant cytoplasmic domain expressed in baculovirus expression system using FAM-labeled peptide ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-3(Human)
Wuxi Apptec

Curated by ChEMBL
LigandPNGBDBM50467141(CHEMBL4283517)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant human GST-tagged EGFR L858R mutant cytoplasmic domain expressed in baculovirus expression system using FAM-labeled peptide ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-3(Human)
Wuxi Apptec

Curated by ChEMBL
LigandPNGBDBM50467145(CHEMBL4282879)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant human GST-tagged EGFR L858R mutant cytoplasmic domain expressed in baculovirus expression system using FAM-labeled peptide ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
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