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TargetHomeodomain-interacting protein kinase 4(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50172243(CHEMBL3103192)
Affinity DataIC50: 40nMAssay Description:Inhibition of Hipk4 (unknown origin) by quantitative PCRMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHomeodomain-interacting protein kinase 4(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM16673(Xarelto | BAY439006 | CHEMBL1336 | BAY 43-9006 | 4...)
Affinity DataIC50: 100nMAssay Description:Inhibition of HIPK4 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHomeodomain-interacting protein kinase 4(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50399540(FORETINIB | US10464902, Foretinib | US10882853, Co...)
Affinity DataIC50: 100nMAssay Description:Inhibition of HIPK4 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHomeodomain-interacting protein kinase 4(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50242737((R,Z)-5-(2,6-dichlorobenzylsulfonyl)-3-((3,5-dimet...)
Affinity DataIC50: 100nMAssay Description:Inhibition of HIPK4 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHomeodomain-interacting protein kinase 4(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM17055((9S)-9-[(dimethylamino)methyl]-6,7,10,11-tetrahydr...)
Affinity DataIC50: 100nMAssay Description:Inhibition of HIPK4 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHomeodomain-interacting protein kinase 4(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50563891(CHEMBL4793380)
Affinity DataIC50: 127nMAssay Description:Inhibition of human HIPK4 using RRRFRPASPLRGPPK as substrate after 40 mins by [gamma-33ATP] radiometric assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetHomeodomain-interacting protein kinase 4(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM2579(CHEMBL388978 | Staurosporine, 8 | Staurosporin, 4 ...)
Affinity DataIC50: 138nMAssay Description:Inhibition of human HIPK4 using MBP as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHomeodomain-interacting protein kinase 4(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50506351(CHEMBL4439133)
Affinity DataIC50: 176nMAssay Description:Inhibition of recombinant full-length human N-terminal GST-tagged HIPK4 expressed in baculovirus expression system by Z'-LYTE assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetHomeodomain-interacting protein kinase 4(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM2579(CHEMBL388978 | Staurosporine, 8 | Staurosporin, 4 ...)
Affinity DataIC50: 314nMAssay Description:Inhibition of human HIPK4 using MBP as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHomeodomain-interacting protein kinase 4(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50526803(CHEMBL4434871 | US10870651, Compound 101)
Affinity DataIC50: 550nMAssay Description:Compounds of the invention were assayed for activity against a variety of different kinases.More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetHomeodomain-interacting protein kinase 4(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50627464(CHEMBL5426285)
Affinity DataIC50: 620nMAssay Description:Inhibition of human HIPK4 assessed as remaining activity by eurofins-cerep kinase profiler analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails
PubMed
TargetHomeodomain-interacting protein kinase 4(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM311261(US10155760, Example 117 | (S)-methyl (5-((2-amino-...)
Affinity DataIC50: 650nMAssay Description:Inhibition of HIPK4 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetHomeodomain-interacting protein kinase 4(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM311210(US10155760, Example 66 | (S)-methyl (5-((2-amino-2...)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of HIPK4 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetHomeodomain-interacting protein kinase 4(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50604141(CHEMBL5188433)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of HIPK4 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetHomeodomain-interacting protein kinase 4(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50604138(CHEMBL5184381)
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of HIPK4 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetHomeodomain-interacting protein kinase 4(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50519662(CHEMBL4438748)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant full length HIPK4 using RRRFRPASPLRGP as substrate after 40 mins by [gamma-33ATP] radiometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHomeodomain-interacting protein kinase 4(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50135286(CHEMBL3745885)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human HIPK4 using MBP as substrateMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHomeodomain-interacting protein kinase 4(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50499634(CHEMBL3741589)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of HIPK4 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHomeodomain-interacting protein kinase 4(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50631397(CHEMBL5432402)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human HIPK4 assessed as remaining activity by eurofins-cerep kinase profiler analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetHomeodomain-interacting protein kinase 4(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50537742(CHEMBL4634634 | US11179389, Compound 1-14)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of recombinant full length human N-terminal GST-tagged HIPK4 expressed in baculovirus expression system using serine/threonine-18 peptide ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed