Compile Data Set for Download or QSAR
Report error Found 94 of ic50 data for polymerid = 50003963,50007219
TargetDiacylglycerol lipase-beta(Mouse)
Leiden University

Curated by ChEMBL
LigandPNGBDBM434879(US10583137, Compound 17 | tert-Butyl 3-benzyl-4-(4...)
Affinity DataIC50: 2.5nMAssay Description:Inhibition mouse DAGLbeta expressed in HEK293T cell membrane fractions using DAG as substrate preincubated for 30 mins followed by ABP HT01 probe add...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDiacylglycerol lipase-beta(Mouse)
Leiden University

Curated by ChEMBL
LigandPNGBDBM434879(US10583137, Compound 17 | tert-Butyl 3-benzyl-4-(4...)
Affinity DataIC50: 2.5nMAssay Description:Inhibition mouse DAGLbeta expressed in HEK293T cell membrane fractions using DAG as substrate preincubated for 30 mins followed by ABP HT01 probe add...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDiacylglycerol lipase-beta(Mouse)
Leiden University

Curated by ChEMBL
LigandPNGBDBM50211257(CHEMBL3895863 | US10583137, Compound 14)
Affinity DataIC50: 5nMAssay Description:Inhibition mouse DAGLbeta expressed in HEK293T cell membrane fractions using DAG as substrate preincubated for 30 mins followed by ABP HT01 probe add...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDiacylglycerol lipase-beta(Mouse)
Leiden University

Curated by ChEMBL
LigandPNGBDBM50211257(CHEMBL3895863 | US10583137, Compound 14)
Affinity DataIC50: 5nMAssay Description:Inhibition mouse DAGLbeta expressed in HEK293T cell membrane fractions using DAG as substrate preincubated for 30 mins followed by ABP HT01 probe add...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDiacylglycerol lipase-beta(Human)
Leiden University

Curated by ChEMBL
LigandPNGBDBM50532885(CHEMBL4470017)
Affinity DataIC50: 6.30nMAssay Description:Inhibition of human GST-tagged DAGLbeta catalytic domain expressed in HEK293F cell membranes using EnzChek as substrate preincubated for 5 mins follo...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails Article
PubMed
TargetDiacylglycerol lipase-beta(Human)
Leiden University

Curated by ChEMBL
LigandPNGBDBM50532885(CHEMBL4470017)
Affinity DataIC50: 6.30nMAssay Description:Inhibition of human GST-tagged DAGLbeta catalytic domain expressed in HEK293F cell membranes using EnzChek as substrate preincubated for 5 mins follo...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails Article
PubMed
TargetDiacylglycerol lipase-beta(Mouse)
Leiden University

Curated by ChEMBL
LigandPNGBDBM434879(US10583137, Compound 17 | tert-Butyl 3-benzyl-4-(4...)
Affinity DataIC50: 7.90nMAssay Description:Inhibition of mouse DAGLbeta expressed in HEK293T cell membranes using SAG as substrate preincubated for 30 mins followed by substrate addition by en...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDiacylglycerol lipase-beta(Mouse)
Leiden University

Curated by ChEMBL
LigandPNGBDBM434879(US10583137, Compound 17 | tert-Butyl 3-benzyl-4-(4...)
Affinity DataIC50: 7.90nMAssay Description:Inhibition of mouse DAGLbeta expressed in HEK293T cell membranes using SAG as substrate preincubated for 30 mins followed by substrate addition by en...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDiacylglycerol lipase-beta(Mouse)
Leiden University

Curated by ChEMBL
LigandPNGBDBM50211260(CHEMBL3964338)
Affinity DataIC50: 13nMAssay Description:Inhibition of HT-01 probe binding to recombinant mouse DAGLbeta expressed in HEK293T cell membrane proteomes preincubated for 30 mins followed by HT-...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDiacylglycerol lipase-beta(Human)
Leiden University

Curated by ChEMBL
LigandPNGBDBM50532882(CHEMBL4476210)
Affinity DataIC50: 25nMAssay Description:Inhibition of human GST-tagged DAGLbeta catalytic domain expressed in HEK293F cell membranes using EnzChek as substrate preincubated for 5 mins follo...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDiacylglycerol lipase-beta(Human)
Leiden University

Curated by ChEMBL
LigandPNGBDBM50532882(CHEMBL4476210)
Affinity DataIC50: 25nMAssay Description:Inhibition of human GST-tagged DAGLbeta catalytic domain expressed in HEK293F cell membranes using EnzChek as substrate preincubated for 5 mins follo...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDiacylglycerol lipase-beta(Mouse)
Leiden University

Curated by ChEMBL
LigandPNGBDBM50211236(CHEMBL2144065)
Affinity DataIC50: 40nMAssay Description:Inhibition mouse DAGLbeta expressed in HEK293T cell membrane fractions using DAG as substrate preincubated for 30 mins followed by ABP HT01 probe add...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDiacylglycerol lipase-beta(Mouse)
Leiden University

Curated by ChEMBL
LigandPNGBDBM50211236(CHEMBL2144065)
Affinity DataIC50: 40nMAssay Description:Inhibition of HT-01 probe binding to recombinant mouse DAGLbeta expressed in HEK293T cell membrane proteomes preincubated for 30 mins followed by HT-...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDiacylglycerol lipase-beta(Human)
Leiden University

Curated by ChEMBL
LigandPNGBDBM50147615(CHEMBL3764876)
Affinity DataIC50: 40nMAssay Description:Inhibition of DAGLbeta (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDiacylglycerol lipase-beta(Human)
Leiden University

Curated by ChEMBL
LigandPNGBDBM50148158(CHEMBL3764017)
Affinity DataIC50: 40nMAssay Description:Inhibition of DAGLbeta (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDiacylglycerol lipase-beta(Mouse)
Leiden University

Curated by ChEMBL
LigandPNGBDBM50211236(CHEMBL2144065)
Affinity DataIC50: 40nMAssay Description:Inhibition mouse DAGLbeta expressed in HEK293T cell membrane fractions using DAG as substrate preincubated for 30 mins followed by ABP HT01 probe add...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDiacylglycerol lipase-beta(Human)
Leiden University

Curated by ChEMBL
LigandPNGBDBM24567(Tetrahydrolipstatin | CHEMBL175247 | Xenical | (2S...)
Affinity DataIC50: 60nMAssay Description:Inhibition of human recombinant DAGLbeta overexpressed in african green monkey COS7 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDiacylglycerol lipase-beta(Human)
Leiden University

Curated by ChEMBL
LigandPNGBDBM50240877(Quinolyl derivatives | cyclohexanone O-6-((cyclohe...)
Affinity DataIC50: 60nMAssay Description:Inhibition of human recombinant DAGLbeta overexpressed in african green monkey COS7 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDiacylglycerol lipase-beta(Mouse)
Leiden University

Curated by ChEMBL
LigandPNGBDBM50532883(CHEMBL2136920)
Affinity DataIC50: 63nMAssay Description:Inhibition mouse DAGLbeta expressed in HEK293T cell membrane fractions using DAG as substrate preincubated for 30 mins followed by ABP HT01 probe add...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDiacylglycerol lipase-beta(Mouse)
Leiden University

Curated by ChEMBL
LigandPNGBDBM50532883(CHEMBL2136920)
Affinity DataIC50: 63nMAssay Description:Inhibition mouse DAGLbeta expressed in HEK293T cell membrane fractions using DAG as substrate preincubated for 30 mins followed by ABP HT01 probe add...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDiacylglycerol lipase-beta(Mouse)
Leiden University

Curated by ChEMBL
LigandPNGBDBM50211236(CHEMBL2144065)
Affinity DataIC50: 79nMAssay Description:Inhibition of V-tagged mouse DAGLbeta expressed in HEK2934T cell membrane fractions using SAG as substrate assessed as accumulation of 2-AG preincuba...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDiacylglycerol lipase-beta(Mouse)
Leiden University

Curated by ChEMBL
LigandPNGBDBM50532883(CHEMBL2136920)
Affinity DataIC50: 79nMAssay Description:Inhibition of V-tagged mouse DAGLbeta expressed in HEK2934T cell membrane fractions using SAG as substrate assessed as accumulation of 2-AG preincuba...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDiacylglycerol lipase-beta(Mouse)
Leiden University

Curated by ChEMBL
LigandPNGBDBM50532883(CHEMBL2136920)
Affinity DataIC50: 79nMAssay Description:Inhibition of V-tagged mouse DAGLbeta expressed in HEK2934T cell membrane fractions using SAG as substrate assessed as accumulation of 2-AG preincuba...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDiacylglycerol lipase-beta(Mouse)
Leiden University

Curated by ChEMBL
LigandPNGBDBM50211236(CHEMBL2144065)
Affinity DataIC50: 79nMAssay Description:Inhibition of V-tagged mouse DAGLbeta expressed in HEK2934T cell membrane fractions using SAG as substrate assessed as accumulation of 2-AG preincuba...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDiacylglycerol lipase-beta(Mouse)
Leiden University

Curated by ChEMBL
LigandPNGBDBM50211236(CHEMBL2144065)
Affinity DataIC50: 79nMAssay Description:Inhibition of recombinant mouse DAGLbeta expressed in HEK293T cell membranes using PNP butyrate as substrate by colorimetric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDiacylglycerol lipase-beta(Mouse)
Leiden University

Curated by ChEMBL
LigandPNGBDBM50211235(CHEMBL3974512)
Affinity DataIC50: 79nMAssay Description:Inhibition of HT-01 probe binding to recombinant mouse DAGLbeta expressed in HEK293T cell membrane proteomes preincubated for 30 mins followed by HT-...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDiacylglycerol lipase-beta(Human)
Leiden University

Curated by ChEMBL
LigandPNGBDBM50148187(CHEMBL3764093)
Affinity DataIC50: 80nMAssay Description:Inhibition of DAGLbeta (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDiacylglycerol lipase-beta(Mouse)
Leiden University

Curated by ChEMBL
LigandPNGBDBM50532882(CHEMBL4476210)
Affinity DataIC50: 100nMAssay Description:Inhibition of full length 3' FLAG-tagged mouse DAGLbeta expressed in African green monkey COS7 cells using sn-1-stearoyl-[14C]-arachidonoyl-glycerol ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDiacylglycerol lipase-beta(Mouse)
Leiden University

Curated by ChEMBL
LigandPNGBDBM50532882(CHEMBL4476210)
Affinity DataIC50: 100nMAssay Description:Inhibition of full length 3' FLAG-tagged mouse DAGLbeta expressed in African green monkey COS7 cells using sn-1-stearoyl-[14C]-arachidonoyl-glycerol ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDiacylglycerol lipase-beta(Human)
Leiden University

Curated by ChEMBL
LigandPNGBDBM50147618(CHEMBL3765022)
Affinity DataIC50: 112nMAssay Description:Inhibition of DAGLbeta (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDiacylglycerol lipase-beta(Human)
Leiden University

Curated by ChEMBL
LigandPNGBDBM50147617(CHEMBL3765421)
Affinity DataIC50: 146nMAssay Description:Inhibition of DAGLbeta (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDiacylglycerol lipase-beta(Human)
Leiden University

Curated by ChEMBL
LigandPNGBDBM434939(US10583137, Compound 136 | N-(2-ethylbutyl)-N-(2-(...)
Affinity DataIC50: 400nMAssay Description:Briefly, membrane proteome (1 mg/ml, 20 μL) was prepared from HEK293T cells (transiently transfected with hDAGLα-FLAG or hDAGLα-S472A-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetDiacylglycerol lipase-beta(Human)
Leiden University

Curated by ChEMBL
LigandPNGBDBM434937(US10583137, Compound 134 | N-neopentyl-N-(2-(pyrid...)
Affinity DataIC50: 400nMAssay Description:Briefly, membrane proteome (1 mg/ml, 20 μL) was prepared from HEK293T cells (transiently transfected with hDAGLα-FLAG or hDAGLα-S472A-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetDiacylglycerol lipase-beta(Human)
Leiden University

Curated by ChEMBL
LigandPNGBDBM434935(US10583137, Compound 132 | N-neopentyl-N-(2-(pyrid...)
Affinity DataIC50: 400nMAssay Description:Briefly, membrane proteome (1 mg/ml, 20 μL) was prepared from HEK293T cells (transiently transfected with hDAGLα-FLAG or hDAGLα-S472A-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetDiacylglycerol lipase-beta(Human)
Leiden University

Curated by ChEMBL
LigandPNGBDBM434933(US10583137, Compound 130 | N-(cyclopropylmethyl)-N...)
Affinity DataIC50: 400nMAssay Description:Briefly, membrane proteome (1 mg/ml, 20 μL) was prepared from HEK293T cells (transiently transfected with hDAGLα-FLAG or hDAGLα-S472A-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetDiacylglycerol lipase-beta(Human)
Leiden University

Curated by ChEMBL
LigandPNGBDBM434930(US10583137, Compound 127 | N-neopentyl-N-phenethyl...)
Affinity DataIC50: 400nMAssay Description:Briefly, membrane proteome (1 mg/ml, 20 μL) was prepared from HEK293T cells (transiently transfected with hDAGLα-FLAG or hDAGLα-S472A-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetDiacylglycerol lipase-beta(Human)
Leiden University

Curated by ChEMBL
LigandPNGBDBM434929(US10583137, Compound 126 | N-(2-ethylbutyl)-N-phen...)
Affinity DataIC50: 400nMAssay Description:Briefly, membrane proteome (1 mg/ml, 20 μL) was prepared from HEK293T cells (transiently transfected with hDAGLα-FLAG or hDAGLα-S472A-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetDiacylglycerol lipase-beta(Human)
Leiden University

Curated by ChEMBL
LigandPNGBDBM434928(US10583137, Compound 125 | N-cyclopropyl-N-pheneth...)
Affinity DataIC50: 400nMAssay Description:Briefly, membrane proteome (1 mg/ml, 20 μL) was prepared from HEK293T cells (transiently transfected with hDAGLα-FLAG or hDAGLα-S472A-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetDiacylglycerol lipase-beta(Human)
Leiden University

Curated by ChEMBL
LigandPNGBDBM434927(US10583137, Compound 124 | N-cyclobutyl-N-phenethy...)
Affinity DataIC50: 400nMAssay Description:Briefly, membrane proteome (1 mg/ml, 20 μL) was prepared from HEK293T cells (transiently transfected with hDAGLα-FLAG or hDAGLα-S472A-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetDiacylglycerol lipase-beta(Human)
Leiden University

Curated by ChEMBL
LigandPNGBDBM434926(US10583137, Compound 123 | N-neopentyl-N-phenethyl...)
Affinity DataIC50: 400nMAssay Description:Briefly, membrane proteome (1 mg/ml, 20 μL) was prepared from HEK293T cells (transiently transfected with hDAGLα-FLAG or hDAGLα-S472A-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetDiacylglycerol lipase-beta(Human)
Leiden University

Curated by ChEMBL
LigandPNGBDBM434925(US10583137, Compound 122 | N-(2-ethylbutyl)-N-phen...)
Affinity DataIC50: 400nMAssay Description:Briefly, membrane proteome (1 mg/ml, 20 μL) was prepared from HEK293T cells (transiently transfected with hDAGLα-FLAG or hDAGLα-S472A-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetDiacylglycerol lipase-beta(Human)
Leiden University

Curated by ChEMBL
LigandPNGBDBM434920(US10583137, Compound 90 | (2-benzylpiperidin-1-yl)...)
Affinity DataIC50: 400nMAssay Description:Briefly, membrane proteome (1 mg/ml, 20 μL) was prepared from HEK293T cells (transiently transfected with hDAGLα-FLAG or hDAGLα-S472A-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetDiacylglycerol lipase-beta(Human)
Leiden University

Curated by ChEMBL
LigandPNGBDBM434919(US10583137, Compound 89 | (2-benzylpiperidin-1-yl)...)
Affinity DataIC50: 400nMAssay Description:Briefly, membrane proteome (1 mg/ml, 20 μL) was prepared from HEK293T cells (transiently transfected with hDAGLα-FLAG or hDAGLα-S472A-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetDiacylglycerol lipase-beta(Human)
Leiden University

Curated by ChEMBL
LigandPNGBDBM434918(US10583137, Compound 88 | 4-(1-(2-benzylpiperidine...)
Affinity DataIC50: 400nMAssay Description:Briefly, membrane proteome (1 mg/ml, 20 μL) was prepared from HEK293T cells (transiently transfected with hDAGLα-FLAG or hDAGLα-S472A-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetDiacylglycerol lipase-beta(Human)
Leiden University

Curated by ChEMBL
LigandPNGBDBM434913(US10583137, Compound 87 | (2-benzylpiperidin-1-yl)...)
Affinity DataIC50: 400nMAssay Description:Briefly, membrane proteome (1 mg/ml, 20 μL) was prepared from HEK293T cells (transiently transfected with hDAGLα-FLAG or hDAGLα-S472A-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetDiacylglycerol lipase-beta(Human)
Leiden University

Curated by ChEMBL
LigandPNGBDBM434908(US10583137, Compound 86 | (2-benzylpiperidin-1-yl)...)
Affinity DataIC50: 400nMAssay Description:Briefly, membrane proteome (1 mg/ml, 20 μL) was prepared from HEK293T cells (transiently transfected with hDAGLα-FLAG or hDAGLα-S472A-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetDiacylglycerol lipase-beta(Human)
Leiden University

Curated by ChEMBL
LigandPNGBDBM434892(US10583137, Compound 66 | (4-([1,1'-biphenyl]-4-yl...)
Affinity DataIC50: 400nMAssay Description:Briefly, membrane proteome (1 mg/ml, 20 μL) was prepared from HEK293T cells (transiently transfected with hDAGLα-FLAG or hDAGLα-S472A-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetDiacylglycerol lipase-beta(Human)
Leiden University

Curated by ChEMBL
LigandPNGBDBM434899(US10583137, Compound 73 | (2-benzylpiperidin-1-yl)...)
Affinity DataIC50: 400nMAssay Description:Briefly, membrane proteome (1 mg/ml, 20 μL) was prepared from HEK293T cells (transiently transfected with hDAGLα-FLAG or hDAGLα-S472A-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetDiacylglycerol lipase-beta(Human)
Leiden University

Curated by ChEMBL
LigandPNGBDBM434908(US10583137, Compound 86 | (2-benzylpiperidin-1-yl)...)
Affinity DataIC50: 400nMAssay Description:Briefly, membrane proteome (1 mg/ml, 20 μL) was prepared from HEK293T cells (transiently transfected with hDAGLα-FLAG or hDAGLα-S472A-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetDiacylglycerol lipase-beta(Human)
Leiden University

Curated by ChEMBL
LigandPNGBDBM434882(US10583137, Compound 53 | N-(2-Ethylbutyl)-N-(2-(p...)
Affinity DataIC50: 400nMAssay Description:Briefly, membrane proteome (1 mg/ml, 20 μL) was prepared from HEK293T cells (transiently transfected with hDAGLα-FLAG or hDAGLα-S472A-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

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