Compile Data Set for Download or QSAR
Report error Found 382 of ic50 data for polymerid = 50003956
TargetHuntingtin(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50578375(CHEMBL4875017)
Affinity DataIC50: 1.60nMAssay Description:Inhibition of endogenous Huntingtin protein (unknown origin) incubated for overnight in presence of MW1/MAB2166 monoclonal antibody by ELISA-based MS...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetHuntingtin(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50578380(CHEMBL4878942)
Affinity DataIC50: 1.70nMAssay Description:Inhibition of endogenous Huntingtin protein (unknown origin) incubated for overnight in presence of MW1/MAB2166 monoclonal antibody by ELISA-based MS...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetHuntingtin(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50578376(CHEMBL4863336)
Affinity DataIC50: 2.10nMAssay Description:Inhibition of endogenous Huntingtin protein (unknown origin) incubated for overnight in presence of MW1/MAB2166 monoclonal antibody by ELISA-based MS...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetHuntingtin(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50578377(CHEMBL4847156)
Affinity DataIC50: 2.10nMAssay Description:Inhibition of endogenous Huntingtin protein (unknown origin) incubated for overnight in presence of MW1/MAB2166 monoclonal antibody by ELISA-based MS...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetHuntingtin(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50578378(CHEMBL4867927)
Affinity DataIC50: 2.20nMAssay Description:Inhibition of endogenous Huntingtin protein (unknown origin) incubated for overnight in presence of MW1/MAB2166 monoclonal antibody by ELISA-based MS...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetHuntingtin(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50578379(CHEMBL4859053)
Affinity DataIC50: 2.30nMAssay Description:Inhibition of endogenous Huntingtin protein (unknown origin) incubated for overnight in presence of MW1/MAB2166 monoclonal antibody by ELISA-based MS...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetHuntingtin(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50595435(CHEMBL5179682)
Affinity DataIC50: 8nMAssay Description:Inhibition of HTT (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetHuntingtin(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50595435(CHEMBL5179682)
Affinity DataIC50: 8nMAssay Description:Inhibition of HTT (unknown origin) by HTS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetHuntingtin(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM37533((2E,4S,4aS,5aS,6S,12aS)-2-[amino(hydroxy)methylide...)
Affinity DataIC50: 10nMAssay Description:The mutation underlying Huntington's disease is an expansion of a polyglutamine tract in the N-terminus of the protein huntingtin (htt). Under no...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2011
Entry Details
PCBioAssay
TargetHuntingtin(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM37535(cid_6603543 | SMR000059002 | MLS000069428 | CHLORT...)
Affinity DataIC50: 10nMAssay Description:The mutation underlying Huntington's disease is an expansion of a polyglutamine tract in the N-terminus of the protein huntingtin (htt). Under no...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2011
Entry Details
PCBioAssay
TargetHuntingtin(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50595433(CHEMBL5195936)
Affinity DataIC50: 40nMAssay Description:Inhibition of HTT (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetHuntingtin(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50595433(CHEMBL5195936)
Affinity DataIC50: 40nMAssay Description:Inhibition of HTT (unknown origin) by HTS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetHuntingtin(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM32023(SMR000058220 | (2E,4S,4aS,5aS,6S,12aS)-2-[amino(hy...)
Affinity DataIC50: 80nMAssay Description:The mutation underlying Huntington's disease is an expansion of a polyglutamine tract in the N-terminus of the protein huntingtin (htt). Under no...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2011
Entry Details
PCBioAssay
TargetHuntingtin(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50595434(CHEMBL5175104)
Affinity DataIC50: 80nMAssay Description:Inhibition of HTT (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetHuntingtin(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50595434(CHEMBL5175104)
Affinity DataIC50: 80nMAssay Description:Inhibition of HTT (unknown origin) by HTS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetHuntingtin(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM37534(MINOCYCLINE HYDROCHLORIDE | (2E,4R,12aR)-2-[amino(...)
Affinity DataIC50: 100nMAssay Description:The mutation underlying Huntington's disease is an expansion of a polyglutamine tract in the N-terminus of the protein huntingtin (htt). Under no...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2011
Entry Details
PCBioAssay
TargetHuntingtin(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM37536((2E,4S,4aR,5S,5aR,6S,12aS)-2-[azanyl(oxidanyl)meth...)
Affinity DataIC50: 100nMAssay Description:The mutation underlying Huntington's disease is an expansion of a polyglutamine tract in the N-terminus of the protein huntingtin (htt). Under no...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2011
Entry Details
PCBioAssay
TargetHuntingtin(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM96500(cid_7497069 | MLS001157845 | N'-[(1E)-1-(1-cyclohe...)
Affinity DataIC50: 450nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2013
Entry Details
PCBioAssay
TargetHuntingtin(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM96499(cid_5928270 | MLS001158344 | N'-[(1Z)-1-[1-cyclohe...)
Affinity DataIC50: 452nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2013
Entry Details
PCBioAssay
TargetHuntingtin(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM96534(SMR001282215 | N-(5-chloranylthiophen-2-yl)sulfony...)
Affinity DataIC50: 462nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2013
Entry Details
PCBioAssay
TargetHuntingtin(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM96471(methyl 3-[(2E)-2-(1-cyano-2-oxo-2-phenylethylidene...)
Affinity DataIC50: 561nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2013
Entry Details
PCBioAssay
TargetHuntingtin(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM64759(3-[2-furanyl(oxo)methyl]-4-hydroxy-1-(6-methyl-1,3...)
Affinity DataIC50: 624nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2013
Entry Details
PCBioAssay
TargetHuntingtin(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM58741(methyl 2-[4-hydroxy-3-(5-methylfuran-2-carbonyl)-2...)
Affinity DataIC50: 636nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2013
Entry Details
PCBioAssay
TargetHuntingtin(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50257650(CHEMBL493153 | cid_23631972 | 4-(2-(6-chloroquinaz...)
Affinity DataIC50: 710nMAssay Description:Inhibition of Huntingtin protein aggregation by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHuntingtin(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50256(cid_1595371 | (5E)-1-butyl-5-[(E)-3-(furan-2-yl)pr...)
Affinity DataIC50: 721nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2013
Entry Details
PCBioAssay
TargetHuntingtin(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM48867((5Z)-4-methyl-5-[[5-(4-methyl-2-nitrophenyl)furan-...)
Affinity DataIC50: 784nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2013
Entry Details
PCBioAssay
TargetHuntingtin(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM96419(6-chloranyl-N-[2-(2-chlorophenyl)ethyl]-5-methyl-7...)
Affinity DataIC50: 796nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2013
Entry Details
PCBioAssay
TargetHuntingtin(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM53725(N-[(5Z)-5-[(4,5-dimethoxy-2-nitrophenyl)methyliden...)
Affinity DataIC50: 848nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2013
Entry Details
PCBioAssay
TargetHuntingtin(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM90877(MLS001199048 | cid_16012569 | 3-[(3-fluorobenzoyl)...)
Affinity DataIC50: 859nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2013
Entry Details
PCBioAssay
TargetHuntingtin(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM53935(4-methyl-N-[(5Z)-4-oxo-5-(phenylmethylene)-2-thiaz...)
Affinity DataIC50: 879nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2013
Entry Details
PCBioAssay
TargetHuntingtin(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM61891(cid_3152768 | 1-(6-chloro-1,3-benzothiazol-2-yl)-2...)
Affinity DataIC50: 987nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2013
Entry Details
PCBioAssay
TargetHuntingtin(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM96413(SMR000066316 | 6-(2-furanyl)-3-methyl-1-phenyl-4-p...)
Affinity DataIC50: 1.01E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2013
Entry Details
PCBioAssay
TargetHuntingtin(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM96462(MLS000516399 | 2-[(6E)-6-[(4-methoxyphenyl)methyli...)
Affinity DataIC50: 1.01E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2013
Entry Details
PCBioAssay
TargetHuntingtin(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM70228(3-[5-[(Z)-(5-imino-7-oxo-3-propan-2-ylsulfonyl-[1,...)
Affinity DataIC50: 1.06E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2013
Entry Details
PCBioAssay
TargetHuntingtin(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM54149(cid_2807878 | 5-thiophen-3-yl-3-[[4-(trifluorometh...)
Affinity DataIC50: 1.06E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2013
Entry Details
PCBioAssay
TargetHuntingtin(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50257498(4-(4-(benzo[d][1,3]dioxol-5-ylmethyl)piperazin-1-y...)
Affinity DataIC50: 1.07E+3nMAssay Description:Inhibition of Huntingtin protein aggregation by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHuntingtin(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM46036(2-[[3-(3-oxidanylidene-1,2-benzothiazol-2-yl)pheny...)
Affinity DataIC50: 1.10E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2013
Entry Details
PCBioAssay
TargetHuntingtin(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM46215(2-[4-[[5-(4-chlorophenyl)-7-methyl-3-oxo-6-[oxo(pr...)
Affinity DataIC50: 1.11E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2013
Entry Details
PCBioAssay
TargetHuntingtin(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50257649(4-(2-(6-bromoquinazolin-4-ylamino)ethyl)phenol | C...)
Affinity DataIC50: 1.11E+3nMAssay Description:Inhibition of Huntingtin protein aggregation by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHuntingtin(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM96446(SMR000260936 | MLS000391903 | cid_2318621)
Affinity DataIC50: 1.12E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2013
Entry Details
PCBioAssay
TargetHuntingtin(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM60895(4-[[3-[(5Z)-5-(2-furanylmethylidene)-4-oxo-2-sulfa...)
Affinity DataIC50: 1.18E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2013
Entry Details
PCBioAssay
TargetHuntingtin(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM75042((6Z)-5-imino-6-(1H-indol-3-ylmethylene)-3-(methyls...)
Affinity DataIC50: 1.19E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2013
Entry Details
PCBioAssay
TargetHuntingtin(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM66209(3-(1-benzofuran-2-ylcarbonyl)-2-(3-chlorophenyl)-1...)
Affinity DataIC50: 1.19E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2013
Entry Details
PCBioAssay
TargetHuntingtin(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50430741(CHEMBL2333942)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of HD exon 1 fusion protein with 51 glutamine residues (unknown origin) aggregation expressed in Escherichia coli SURE after 16 hrs by Wes...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetHuntingtin(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM96523(sodium;(6R,7R)-3-(acetyloxymethyl)-7-[[(2Z)-2-(2-a...)
Affinity DataIC50: 1.21E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2013
Entry Details
PCBioAssay
TargetHuntingtin(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM96424(5-(butylcarbamoyl)-3-(naphthalen-1-ylsulfanylmethy...)
Affinity DataIC50: 1.21E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2013
Entry Details
PCBioAssay
TargetHuntingtin(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM96519(MLS002252338 | cid_2381372 | 4-chloro-2-[[2-[4-[(4...)
Affinity DataIC50: 1.24E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2013
Entry Details
PCBioAssay
TargetHuntingtin(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50258237(cid_720655 | CHEMBL495005 | 6-bromo-4-(4-methylpip...)
Affinity DataIC50: 1.31E+3nMAssay Description:Inhibition of Huntingtin protein aggregation by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHuntingtin(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM96417(5-(4-methylnaphthalen-1-yl)-N-(4-methylphenyl)sulf...)
Affinity DataIC50: 1.34E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2013
Entry Details
PCBioAssay
TargetHuntingtin(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM96537(1-[1-(4-chlorophenyl)cyclobutanecarbonyl]-2-methyl...)
Affinity DataIC50: 1.37E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2013
Entry Details
PCBioAssay
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