Compile Data Set for Download or QSAR
Report error Found 173 of ic50 data for polymerid = 50003362
TargetC-C chemokine receptor type 8(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50203831(N-(4-{[(1-butyrylpiperidin-4-yl)amino]sulfonyl}-1-...)
Affinity DataIC50: 0.300nMAssay Description:Antagonist activity against human CCR8 expressed in CHO/Galpha16 cells assessed as inhibition of CCL1-induced increase of intracellular calcium by FL...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetC-C chemokine receptor type 8(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50185909(2-(3-((1-(3-(2-chlorophenoxy)benzyl)piperidin-4-yl...)
Affinity DataIC50: 1nMAssay Description:Inhibition of I309-induced chemotaxis in L1.2 cells expressing CCR8More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetC-C chemokine receptor type 8(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50632703(CHEMBL5424187)
Affinity DataIC50: 1nMAssay Description:Antagonist activity against CCR8 (unknown origin) expressed in CHO-K1 cells preincubated for 1 hr followed by CCL1 addition measured after 24 hrs by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetC-C chemokine receptor type 8(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50632695(CHEMBL5404620)
Affinity DataIC50: 1.20nMAssay Description:Antagonist activity against CCR8 (unknown origin) expressed in CHO-K1 cells preincubated for 1 hr followed by CCL1 addition measured after 24 hrs by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetC-C chemokine receptor type 8(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50632707(CHEMBL5397693)
Affinity DataIC50: 1.30nMAssay Description:Antagonist activity against CCR8 (unknown origin) expressed in CHO-K1 cells preincubated for 1 hr followed by CCL1 addition measured after 24 hrs by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetC-C chemokine receptor type 8(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50632708(CHEMBL5411391)
Affinity DataIC50: 1.70nMAssay Description:Antagonist activity against CCR8 (unknown origin) expressed in CHO-K1 cells preincubated for 1 hr followed by CCL1 addition measured after 24 hrs by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetC-C chemokine receptor type 8(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50632709(CHEMBL5412884)
Affinity DataIC50: 1.70nMAssay Description:Antagonist activity against CCR8 (unknown origin) expressed in CHO-K1 cells preincubated for 1 hr followed by CCL1 addition measured after 24 hrs by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetC-C chemokine receptor type 8(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50414981(CHEMBL567417)
Affinity DataIC50: 2.40nMAssay Description:Antagonist activity at human CCR8More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetC-C chemokine receptor type 8(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50414974(CHEMBL568523)
Affinity DataIC50: 2.63nMAssay Description:Antagonist activity at human CCR8More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetC-C chemokine receptor type 8(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50414982(CHEMBL579072)
Affinity DataIC50: 2.63nMAssay Description:Antagonist activity at human CCR8More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetC-C chemokine receptor type 8(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50414980(CHEMBL568294)
Affinity DataIC50: 2.82nMAssay Description:Antagonist activity at human CCR8More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetC-C chemokine receptor type 8(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50185912(2-(4-{1-[3-(2-chloro-phenoxy)-benzyl]-piperidin-4-...)
Affinity DataIC50: 4nMAssay Description:Inhibition of I309-induced chemotaxis in L1.2 cells expressing CCR8More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetC-C chemokine receptor type 8(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50632700(CHEMBL5399936)
Affinity DataIC50: 4nMAssay Description:Antagonist activity against CCR8 (unknown origin) expressed in CHO-K1 cells preincubated for 1 hr followed by CCL1 addition measured after 24 hrs by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetC-C chemokine receptor type 8(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50203882(2-methyl-N-{4-[1-(4-methyl-piperazine-1-carbonyl)-...)
Affinity DataIC50: 4nMAssay Description:Antagonist activity against CCR8 (unknown origin) expressed in CHO-K1 cells preincubated for 1 hr followed by CCL1 addition measured after 24 hrs by ...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetC-C chemokine receptor type 8(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50203869(3-pyrrolidin-1-ylpropyl 4-[({4-[(2-methylbenzoyl)a...)
Affinity DataIC50: 4.20nMAssay Description:Antagonist activity against human CCR8 expressed in CHO/Galpha16 cells assessed as inhibition of CCL1-induced increase of intracellular calcium by FL...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetC-C chemokine receptor type 8(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50414983(CHEMBL574655)
Affinity DataIC50: 4.90nMAssay Description:Antagonist activity at human CCR8More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetC-C chemokine receptor type 8(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50203908(N-(4-{[(1-butyrylpiperidin-4-yl)amino]sulfonyl}-1-...)
Affinity DataIC50: 5.10nMAssay Description:Antagonist activity against human CCR8 expressed in CHO/Galpha16 cells assessed as inhibition of CCL1-induced increase of intracellular calcium by FL...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetC-C chemokine receptor type 8(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50414986(CHEMBL568522)
Affinity DataIC50: 5.62nMAssay Description:Antagonist activity at human CCR8More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetC-C chemokine receptor type 8(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50632699(CHEMBL5404280)
Affinity DataIC50: 6nMAssay Description:Antagonist activity against CCR8 (unknown origin) expressed in CHO-K1 cells preincubated for 1 hr followed by CCL1 addition measured after 24 hrs by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetC-C chemokine receptor type 8(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50632701(CHEMBL5412094)
Affinity DataIC50: 6nMAssay Description:Antagonist activity against CCR8 (unknown origin) expressed in CHO-K1 cells preincubated for 1 hr followed by CCL1 addition measured after 24 hrs by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetC-C chemokine receptor type 8(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50203922(cyclohexanecarboxylic acid [4-(1-butyryl-piperidin...)
Affinity DataIC50: 6.10nMAssay Description:Antagonist activity against human CCR8 expressed in CHO/Galpha16 cells assessed as inhibition of CCL1-induced increase of intracellular calcium by FL...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetC-C chemokine receptor type 8(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50414975(CHEMBL584087)
Affinity DataIC50: 6.61nMAssay Description:Antagonist activity at human CCR8More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetC-C chemokine receptor type 8(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50203899(4-tert-butyl-N-(4-{[(1-butyrylpiperidin-4-yl)amino...)
Affinity DataIC50: 6.90nMAssay Description:Antagonist activity against human CCR8 expressed in CHO/Galpha16 cells assessed as inhibition of CCL1-induced increase of intracellular calcium by FL...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetC-C chemokine receptor type 8(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50203877(N-(4-{[(1-butyrylpiperidin-4-yl)amino]sulfonyl}-1-...)
Affinity DataIC50: 7.65nMAssay Description:Antagonist activity against human CCR8 expressed in CHO/Galpha16 cells assessed as inhibition of CCL1-induced increase of intracellular calcium by FL...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetC-C chemokine receptor type 8(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50414978(CHEMBL566543)
Affinity DataIC50: 8.13nMAssay Description:Antagonist activity at human CCR8More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetC-C chemokine receptor type 8(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50203842(N-(4-{[(1-butyrylpiperidin-4-yl)amino]sulfonyl}-1-...)
Affinity DataIC50: 9.5nMAssay Description:Antagonist activity against human CCR8 expressed in CHO/Galpha16 cells assessed as inhibition of CCL1-induced increase of intracellular calcium by FL...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetC-C chemokine receptor type 8(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50203870(3-(dimethylamino)propyl 4-[({4-[(2-methylbenzoyl)a...)
Affinity DataIC50: 9.80nMAssay Description:Antagonist activity against human CCR8 expressed in CHO/Galpha16 cells assessed as inhibition of CCL1-induced increase of intracellular calcium by FL...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetC-C chemokine receptor type 8(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50203896(N-(4-{[(1-butyrylpiperidin-4-yl)amino]sulfonyl}-1-...)
Affinity DataIC50: 10.8nMAssay Description:Antagonist activity against human CCR8 expressed in CHO/Galpha16 cells assessed as inhibition of CCL1-induced increase of intracellular calcium by FL...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetC-C chemokine receptor type 8(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50185905(4-phenyl-piperidine-4-carboxylic acid {1-[3-(2-met...)
Affinity DataIC50: 11nMAssay Description:Inhibition of I309-induced chemotaxis in L1.2 cells expressing CCR8More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetC-C chemokine receptor type 8(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50414964(CHEMBL271128)
Affinity DataIC50: 11.5nMAssay Description:Antagonist activity at human CCR8More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetC-C chemokine receptor type 8(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50423492(CHEMBL409648)
Affinity DataIC50: 12nMAssay Description:Antagonist activity at CCR8 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetC-C chemokine receptor type 8(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50414964(CHEMBL271128)
Affinity DataIC50: 12nMAssay Description:Antagonist activity at CCR8 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetC-C chemokine receptor type 8(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50203864(N-(4-{[(1-butyrylpiperidin-4-yl)amino]-sulfonyl}-1...)
Affinity DataIC50: 12.5nMAssay Description:Antagonist activity against human CCR8 expressed in CHO/Galpha16 cells assessed as inhibition of CCL1-induced increase of intracellular calcium by FL...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetC-C chemokine receptor type 8(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50632696(CHEMBL5400674)
Affinity DataIC50: 13nMAssay Description:Antagonist activity against CCR8 (unknown origin) expressed in CHO-K1 cells preincubated for 1 hr followed by CCL1 addition measured after 24 hrs by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetC-C chemokine receptor type 8(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50632694(CHEMBL5400852)
Affinity DataIC50: 14nMAssay Description:Antagonist activity against CCR8 (unknown origin) expressed in CHO-K1 cells preincubated for 1 hr followed by CCL1 addition measured after 24 hrs by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetC-C chemokine receptor type 8(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50203887(3-(diethylamino)propyl 4-[({4-[(2-methylbenzoyl)am...)
Affinity DataIC50: 14.5nMAssay Description:Antagonist activity against human CCR8 expressed in CHO/Galpha16 cells assessed as inhibition of CCL1-induced increase of intracellular calcium by FL...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetC-C chemokine receptor type 8(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50414966(CHEMBL573216)
Affinity DataIC50: 14.8nMAssay Description:Antagonist activity at human CCR8More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetC-C chemokine receptor type 8(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50203915(4-butyl-N-(4-{[(1-butyrylpiperidin-4-yl)amino]sulf...)
Affinity DataIC50: 15.3nMAssay Description:Antagonist activity against human CCR8 expressed in CHO/Galpha16 cells assessed as inhibition of CCL1-induced increase of intracellular calcium by FL...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetC-C chemokine receptor type 8(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50411749(CHEMBL271127)
Affinity DataIC50: 16nMAssay Description:Antagonist activity at CCR8 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetC-C chemokine receptor type 8(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50414967(CHEMBL271801)
Affinity DataIC50: 17.4nMAssay Description:Antagonist activity at human CCR8More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetC-C chemokine receptor type 8(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50414967(CHEMBL271801)
Affinity DataIC50: 18nMAssay Description:Antagonist activity at CCR8 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetC-C chemokine receptor type 8(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50414957(CHEMBL429436)
Affinity DataIC50: 19nMAssay Description:Antagonist activity at CCR8 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetC-C chemokine receptor type 8(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50414957(CHEMBL429436)
Affinity DataIC50: 19.1nMAssay Description:Antagonist activity at human CCR8More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetC-C chemokine receptor type 8(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50203907(N-[4-(1-butyryl-piperidin-4-ylsulfamoyl)-naphthale...)
Affinity DataIC50: 19.2nMAssay Description:Antagonist activity against human CCR8 expressed in CHO/Galpha16 cells assessed as inhibition of CCL1-induced increase of intracellular calcium by FL...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetC-C chemokine receptor type 8(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50203893(3-(2,6-dimethylmorpholin-4-yl)propyl-4-[({4-[(2-me...)
Affinity DataIC50: 19.6nMAssay Description:Antagonist activity against human CCR8 expressed in CHO/Galpha16 cells assessed as inhibition of CCL1-induced increase of intracellular calcium by FL...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetC-C chemokine receptor type 8(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50203852(N-(4-{[(1-butyrylpiperidin-4-yl)amino]sulfonyl}-1-...)
Affinity DataIC50: 20nMAssay Description:Antagonist activity against human CCR8 expressed in CHO/Galpha16 cells assessed as inhibition of CCL1-induced increase of intracellular calcium by FL...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetC-C chemokine receptor type 8(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50423246(SB-649701 | CHEMBL245568)
Affinity DataIC50: 20nMAssay Description:Antagonist activity at human recombinant CCR8 expressed in RBL cells assessed as inhibition of I-309-induced intracellular calcium mobilization by FL...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetC-C chemokine receptor type 8(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50203891(N-(4-{[(1-butyrylpiperidin-4-yl)amino]sulfonyl}-1-...)
Affinity DataIC50: 20.4nMAssay Description:Antagonist activity against human CCR8 expressed in CHO/Galpha16 cells assessed as inhibition of CCL1-induced increase of intracellular calcium by FL...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetC-C chemokine receptor type 8(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50185904((+/-) 3-phenyl-pyrrolidine-3-carboxylic acid {1-[3...)
Affinity DataIC50: 22nMAssay Description:Inhibition of I309-induced chemotaxis in L1.2 cells expressing CCR8More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetC-C chemokine receptor type 8(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50414976(CHEMBL566324)
Affinity DataIC50: 22.4nMAssay Description:Antagonist activity at human CCR8More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
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