Report error Found 744 of ic50 data for polymerid = 50003142,50007719
TargetVoltage-dependent T-type calcium channel subunit alpha-1G(Human)
Idorsia Pharmaceuticals
Curated by ChEMBL
Idorsia Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:Inhibition of recombinant Cav3.1 (unknown origin) expressed in HEK293 cells assessed as decrease in calcium flux preincubated for 3 mins followed by ...More data for this Ligand-Target Pair
TargetVoltage-dependent T-type calcium channel subunit alpha-1G(Human)
Idorsia Pharmaceuticals
Curated by ChEMBL
Idorsia Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 1.10nMAssay Description:Inhibition of recombinant Cav3.1 (unknown origin) expressed in HEK293 cells assessed as decrease in calcium flux preincubated for 3 mins followed by ...More data for this Ligand-Target Pair
TargetVoltage-dependent T-type calcium channel subunit alpha-1G(Human)
Idorsia Pharmaceuticals
Curated by ChEMBL
Idorsia Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 1.10nMAssay Description:Inhibition of recombinant Cav3.1 (unknown origin) expressed in HEK293 cells assessed as decrease in calcium flux preincubated for 3 mins followed by ...More data for this Ligand-Target Pair
TargetVoltage-dependent T-type calcium channel subunit alpha-1G(Human)
Idorsia Pharmaceuticals
Curated by ChEMBL
Idorsia Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 1.10nMAssay Description:Inhibition of recombinant Cav3.1 (unknown origin) expressed in HEK293 cells assessed as decrease in calcium flux preincubated for 3 mins followed by ...More data for this Ligand-Target Pair
TargetVoltage-dependent T-type calcium channel subunit alpha-1G(Human)
Idorsia Pharmaceuticals
Curated by ChEMBL
Idorsia Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 1.20nMAssay Description:Inhibition of human T-type calcium channel Cav3.1 expressed in CHO cells assessed as inhibition of calcium tail current at -90 mV holding potential m...More data for this Ligand-Target Pair
TargetVoltage-dependent T-type calcium channel subunit alpha-1G(Human)
Idorsia Pharmaceuticals
Curated by ChEMBL
Idorsia Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 1.20nMAssay Description:Inhibition of CaV 3.1 channel (unknown origin) expressed in HEK293 cells by FLEPR Ca2+ flux assayMore data for this Ligand-Target Pair
TargetVoltage-dependent T-type calcium channel subunit alpha-1G(Human)
Idorsia Pharmaceuticals
Curated by ChEMBL
Idorsia Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 1.30nMAssay Description:Inhibition of recombinant Cav3.1 (unknown origin) expressed in HEK293 cells assessed as decrease in calcium flux preincubated for 3 mins followed by ...More data for this Ligand-Target Pair
TargetVoltage-dependent T-type calcium channel subunit alpha-1G(Human)
Idorsia Pharmaceuticals
Curated by ChEMBL
Idorsia Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 1.40nMAssay Description:Inhibition of recombinant Cav3.1 (unknown origin) expressed in HEK293 cells assessed as decrease in calcium flux preincubated for 3 mins followed by ...More data for this Ligand-Target Pair
TargetVoltage-dependent T-type calcium channel subunit alpha-1G(Human)
Idorsia Pharmaceuticals
Curated by ChEMBL
Idorsia Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 1.40nMAssay Description:Inhibition of recombinant Cav3.1 (unknown origin) expressed in HEK293 cells assessed as decrease in calcium flux preincubated for 3 mins followed by ...More data for this Ligand-Target Pair
TargetVoltage-dependent T-type calcium channel subunit alpha-1G(Human)
Idorsia Pharmaceuticals
Curated by ChEMBL
Idorsia Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 1.5nMAssay Description:Inhibition of recombinant Cav3.1 (unknown origin) expressed in HEK293 cells assessed as decrease in calcium flux preincubated for 3 mins followed by ...More data for this Ligand-Target Pair
TargetVoltage-dependent T-type calcium channel subunit alpha-1G(Human)
Idorsia Pharmaceuticals
Curated by ChEMBL
Idorsia Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 1.90nMAssay Description:Inhibition of recombinant Cav3.1 (unknown origin) expressed in HEK293 cells assessed as decrease in calcium flux preincubated for 3 mins followed by ...More data for this Ligand-Target Pair
TargetVoltage-dependent T-type calcium channel subunit alpha-1G(Human)
Idorsia Pharmaceuticals
Curated by ChEMBL
Idorsia Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 2.20nMAssay Description:Inhibition of recombinant Cav3.1 (unknown origin) expressed in HEK293 cells assessed as decrease in calcium flux preincubated for 3 mins followed by ...More data for this Ligand-Target Pair
TargetVoltage-dependent T-type calcium channel subunit alpha-1G(Human)
Idorsia Pharmaceuticals
Curated by ChEMBL
Idorsia Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 2.20nMAssay Description:Inhibition of recombinant Cav3.1 (unknown origin) expressed in HEK293 cells assessed as decrease in calcium flux preincubated for 3 mins followed by ...More data for this Ligand-Target Pair
TargetVoltage-dependent T-type calcium channel subunit alpha-1G(Human)
Idorsia Pharmaceuticals
Curated by ChEMBL
Idorsia Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 2.20nMAssay Description:Inhibition of recombinant Cav3.1 (unknown origin) expressed in HEK293 cells assessed as decrease in calcium flux preincubated for 3 mins followed by ...More data for this Ligand-Target Pair
TargetVoltage-dependent T-type calcium channel subunit alpha-1G(Human)
Idorsia Pharmaceuticals
Curated by ChEMBL
Idorsia Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 2.20nMAssay Description:Inhibition of recombinant Cav3.1 (unknown origin) expressed in HEK293 cells assessed as decrease in calcium flux preincubated for 3 mins followed by ...More data for this Ligand-Target Pair
TargetVoltage-dependent T-type calcium channel subunit alpha-1G(Human)
Idorsia Pharmaceuticals
Curated by ChEMBL
Idorsia Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 2.30nMAssay Description:Inhibition of recombinant Cav3.1 (unknown origin) expressed in HEK293 cells assessed as decrease in calcium flux preincubated for 3 mins followed by ...More data for this Ligand-Target Pair
TargetVoltage-dependent T-type calcium channel subunit alpha-1G(Human)
Idorsia Pharmaceuticals
Curated by ChEMBL
Idorsia Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 2.30nMAssay Description:Inhibition of recombinant Cav3.1 (unknown origin) expressed in HEK293 cells assessed as decrease in calcium flux preincubated for 3 mins followed by ...More data for this Ligand-Target Pair
TargetVoltage-dependent T-type calcium channel subunit alpha-1G(Human)
Idorsia Pharmaceuticals
Curated by ChEMBL
Idorsia Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 2.40nMAssay Description:Inhibition of recombinant Cav3.1 (unknown origin) expressed in HEK293 cells assessed as decrease in calcium flux preincubated for 3 mins followed by ...More data for this Ligand-Target Pair
TargetVoltage-dependent T-type calcium channel subunit alpha-1G(Human)
Idorsia Pharmaceuticals
Curated by ChEMBL
Idorsia Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 2.5nMAssay Description:Inhibition of recombinant Cav3.1 (unknown origin) expressed in HEK293 cells assessed as decrease in calcium flux preincubated for 3 mins followed by ...More data for this Ligand-Target Pair
TargetVoltage-dependent T-type calcium channel subunit alpha-1G(Human)
Idorsia Pharmaceuticals
Curated by ChEMBL
Idorsia Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 2.60nMAssay Description:Inhibition of recombinant Cav3.1 (unknown origin) expressed in HEK293 cells assessed as decrease in calcium flux preincubated for 3 mins followed by ...More data for this Ligand-Target Pair
TargetVoltage-dependent T-type calcium channel subunit alpha-1G(Human)
Idorsia Pharmaceuticals
Curated by ChEMBL
Idorsia Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 2.80nMAssay Description:Inhibition of recombinant Cav3.1 (unknown origin) expressed in HEK293 cells assessed as decrease in calcium flux preincubated for 3 mins followed by ...More data for this Ligand-Target Pair
TargetVoltage-dependent T-type calcium channel subunit alpha-1G(Human)
Idorsia Pharmaceuticals
Curated by ChEMBL
Idorsia Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 3.10nMAssay Description:Inhibition of recombinant Cav3.1 (unknown origin) expressed in HEK293 cells assessed as decrease in calcium flux preincubated for 3 mins followed by ...More data for this Ligand-Target Pair
TargetVoltage-dependent T-type calcium channel subunit alpha-1G(Human)
Idorsia Pharmaceuticals
Curated by ChEMBL
Idorsia Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 3.20nMAssay Description:Inhibition of recombinant Cav3.1 (unknown origin) expressed in HEK293 cells assessed as decrease in calcium flux preincubated for 3 mins followed by ...More data for this Ligand-Target Pair
TargetVoltage-dependent T-type calcium channel subunit alpha-1G(Human)
Idorsia Pharmaceuticals
Curated by ChEMBL
Idorsia Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 3.40nMAssay Description:Inhibition of recombinant Cav3.1 (unknown origin) expressed in HEK293 cells assessed as decrease in calcium flux preincubated for 3 mins followed by ...More data for this Ligand-Target Pair
TargetVoltage-dependent T-type calcium channel subunit alpha-1G(Human)
Idorsia Pharmaceuticals
Curated by ChEMBL
Idorsia Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 3.40nMAssay Description:Inhibition of recombinant Cav3.1 (unknown origin) expressed in HEK293 cells assessed as decrease in calcium flux preincubated for 3 mins followed by ...More data for this Ligand-Target Pair
TargetVoltage-dependent T-type calcium channel subunit alpha-1G(Human)
Idorsia Pharmaceuticals
Curated by ChEMBL
Idorsia Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 3.40nMAssay Description:Inhibition of recombinant Cav3.1 (unknown origin) expressed in HEK293 cells assessed as decrease in calcium flux preincubated for 3 mins followed by ...More data for this Ligand-Target Pair
TargetVoltage-dependent T-type calcium channel subunit alpha-1G(Human)
Idorsia Pharmaceuticals
Curated by ChEMBL
Idorsia Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 3.5nMAssay Description:Inhibition of recombinant Cav3.1 (unknown origin) expressed in HEK293 cells assessed as decrease in calcium flux preincubated for 3 mins followed by ...More data for this Ligand-Target Pair
TargetVoltage-dependent T-type calcium channel subunit alpha-1G(Human)
Idorsia Pharmaceuticals
Curated by ChEMBL
Idorsia Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 3.5nMAssay Description:Inhibition of recombinant Cav3.1 (unknown origin) expressed in HEK293 cells assessed as decrease in calcium flux preincubated for 3 mins followed by ...More data for this Ligand-Target Pair
TargetVoltage-dependent T-type calcium channel subunit alpha-1G(Human)
Idorsia Pharmaceuticals
Curated by ChEMBL
Idorsia Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 4nMAssay Description:Channel blocking activity at recombinant human CaV 3.1 channel expressed in HEK293 cells assessed as inhibition of Ca2+ flux preincubated for 3 mins ...More data for this Ligand-Target Pair
TargetVoltage-dependent T-type calcium channel subunit alpha-1G(Human)
Idorsia Pharmaceuticals
Curated by ChEMBL
Idorsia Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 4nMAssay Description:Channel blocking activity at recombinant human CaV 3.1 channel expressed in HEK293 cells assessed as inhibition of Ca2+ flux preincubated for 3 mins ...More data for this Ligand-Target Pair
TargetVoltage-dependent T-type calcium channel subunit alpha-1G(Human)
Idorsia Pharmaceuticals
Curated by ChEMBL
Idorsia Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 4.20nMAssay Description:Inhibition of recombinant Cav3.1 (unknown origin) expressed in HEK293 cells assessed as decrease in calcium flux preincubated for 3 mins followed by ...More data for this Ligand-Target Pair
TargetVoltage-dependent T-type calcium channel subunit alpha-1G(Human)
Idorsia Pharmaceuticals
Curated by ChEMBL
Idorsia Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 4.30nMAssay Description:Inhibition of recombinant Cav3.1 (unknown origin) expressed in HEK293 cells assessed as decrease in calcium flux preincubated for 3 mins followed by ...More data for this Ligand-Target Pair
TargetVoltage-dependent T-type calcium channel subunit alpha-1G(Human)
Idorsia Pharmaceuticals
Curated by ChEMBL
Idorsia Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 4.5nMAssay Description:Cells were plated in 384-well, clear-bottom, black-walled, poly-D-lysine coated plates (Becton Dickinson, Franklin Lake, N.J.) 2 days prior to use in...More data for this Ligand-Target Pair
TargetVoltage-dependent T-type calcium channel subunit alpha-1G(Human)
Idorsia Pharmaceuticals
Curated by ChEMBL
Idorsia Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 4.5nMAssay Description:Inhibition of recombinant Cav3.1 (unknown origin) expressed in HEK293 cells assessed as decrease in calcium flux preincubated for 3 mins followed by ...More data for this Ligand-Target Pair
TargetVoltage-dependent T-type calcium channel subunit alpha-1G(Human)
Idorsia Pharmaceuticals
Curated by ChEMBL
Idorsia Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 4.60nMAssay Description:Inhibition of recombinant Cav3.1 (unknown origin) expressed in HEK293 cells assessed as decrease in calcium flux preincubated for 3 mins followed by ...More data for this Ligand-Target Pair
TargetVoltage-dependent T-type calcium channel subunit alpha-1G(Human)
Idorsia Pharmaceuticals
Curated by ChEMBL
Idorsia Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:Channel blocking activity at recombinant human CaV 3.1 channel expressed in HEK293 cells assessed as inhibition of Ca2+ flux preincubated for 3 mins ...More data for this Ligand-Target Pair
TargetVoltage-dependent T-type calcium channel subunit alpha-1G(Human)
Idorsia Pharmaceuticals
Curated by ChEMBL
Idorsia Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:Inhibition of recombinant Cav3.1 (unknown origin) expressed in HEK293 cells assessed as decrease in calcium flux preincubated for 3 mins followed by ...More data for this Ligand-Target Pair
TargetVoltage-dependent T-type calcium channel subunit alpha-1G(Human)
Idorsia Pharmaceuticals
Curated by ChEMBL
Idorsia Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 5.10nMAssay Description:Inhibition of recombinant Cav3.1 (unknown origin) expressed in HEK293 cells assessed as decrease in calcium flux preincubated for 3 mins followed by ...More data for this Ligand-Target Pair
TargetVoltage-dependent T-type calcium channel subunit alpha-1G(Human)
Idorsia Pharmaceuticals
Curated by ChEMBL
Idorsia Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 6nMAssay Description:Channel blocking activity at recombinant human CaV 3.1 channel expressed in HEK293 cells assessed as inhibition of Ca2+ flux preincubated for 3 mins ...More data for this Ligand-Target Pair
TargetVoltage-dependent T-type calcium channel subunit alpha-1G(Human)
Idorsia Pharmaceuticals
Curated by ChEMBL
Idorsia Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 6.20nMAssay Description:Inhibition of recombinant Cav3.1 (unknown origin) expressed in HEK293 cells assessed as decrease in calcium flux preincubated for 3 mins followed by ...More data for this Ligand-Target Pair
TargetVoltage-dependent T-type calcium channel subunit alpha-1G(Human)
Idorsia Pharmaceuticals
Curated by ChEMBL
Idorsia Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 6.40nMAssay Description:Inhibition of recombinant Cav3.1 (unknown origin) expressed in HEK293 cells assessed as decrease in calcium flux preincubated for 3 mins followed by ...More data for this Ligand-Target Pair
TargetVoltage-dependent T-type calcium channel subunit alpha-1G(Human)
Idorsia Pharmaceuticals
Curated by ChEMBL
Idorsia Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 6.5nMAssay Description:Inhibition of recombinant Cav3.1 (unknown origin) expressed in HEK293 cells assessed as decrease in calcium flux preincubated for 3 mins followed by ...More data for this Ligand-Target Pair
TargetVoltage-dependent T-type calcium channel subunit alpha-1G(Human)
Idorsia Pharmaceuticals
Curated by ChEMBL
Idorsia Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 6.80nMAssay Description:Inhibition of recombinant Cav3.1 (unknown origin) expressed in HEK293 cells assessed as decrease in calcium flux preincubated for 3 mins followed by ...More data for this Ligand-Target Pair
TargetVoltage-dependent T-type calcium channel subunit alpha-1G(Human)
Idorsia Pharmaceuticals
Curated by ChEMBL
Idorsia Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 7nMAssay Description:Channel blocking activity at recombinant human CaV 3.1 channel expressed in HEK293 cells assessed as inhibition of Ca2+ flux preincubated for 3 mins ...More data for this Ligand-Target Pair
TargetVoltage-dependent T-type calcium channel subunit alpha-1G(Human)
Idorsia Pharmaceuticals
Curated by ChEMBL
Idorsia Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 7nMAssay Description:Channel blocking activity at recombinant human CaV 3.1 channel expressed in HEK293 cells assessed as inhibition of Ca2+ flux preincubated for 3 mins ...More data for this Ligand-Target Pair
TargetVoltage-dependent T-type calcium channel subunit alpha-1G(Human)
Idorsia Pharmaceuticals
Curated by ChEMBL
Idorsia Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 7nMAssay Description:Inhibition of recombinant Cav3.1 (unknown origin) expressed in HEK293 cells assessed as decrease in calcium flux preincubated for 3 mins followed by ...More data for this Ligand-Target Pair
TargetVoltage-dependent T-type calcium channel subunit alpha-1G(Human)
Idorsia Pharmaceuticals
Curated by ChEMBL
Idorsia Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 7.10nMAssay Description:Inhibition of recombinant Cav3.1 (unknown origin) expressed in HEK293 cells assessed as decrease in calcium flux preincubated for 3 mins followed by ...More data for this Ligand-Target Pair
TargetVoltage-dependent T-type calcium channel subunit alpha-1G(Human)
Idorsia Pharmaceuticals
Curated by ChEMBL
Idorsia Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 8nMAssay Description:Channel blocking activity at recombinant human CaV 3.1 channel expressed in HEK293 cells assessed as inhibition of Ca2+ flux preincubated for 3 mins ...More data for this Ligand-Target Pair
TargetVoltage-dependent T-type calcium channel subunit alpha-1G(Human)
Idorsia Pharmaceuticals
Curated by ChEMBL
Idorsia Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 8nMAssay Description:Channel blocking activity at recombinant human CaV 3.1 channel expressed in HEK293 cells assessed as inhibition of Ca2+ flux preincubated for 3 mins ...More data for this Ligand-Target Pair
TargetVoltage-dependent T-type calcium channel subunit alpha-1G(Human)
Idorsia Pharmaceuticals
Curated by ChEMBL
Idorsia Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 8.10nMAssay Description:Inhibition of recombinant Cav3.1 (unknown origin) expressed in HEK293 cells assessed as decrease in calcium flux preincubated for 3 mins followed by ...More data for this Ligand-Target Pair
