Compile Data Set for Download or QSAR
Report error Found 176 of ic50 data for polymerid = 50001763,50002301,50007289
TargetAdenylate cyclase type 1(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50001884(8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b...)
Affinity DataIC50: 1.40nMAssay Description:Inhibition of dopamine-sensitive rat brain adenylyl cyclase activity assessed as cAMP levelMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenylate cyclase type 1(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50497055(CHEMBL3244459)
Affinity DataIC50: 4.5nMAssay Description:Inhibition of dopamine-sensitive rat brain adenylyl cyclase activity assessed as cAMP levelMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetAdenylate cyclase type 1(Human)
Food and Drug Administration

Curated by ChEMBL
LigandPNGBDBM50052137(Acetic acid (3R,4aR,5S,6S,6aS,10S,10aR,10bS)-10,10...)
Affinity DataIC50: 21nMAssay Description:Inhibition of [125 I]6-IHPP-forskolin binding to adenylate cyclase 1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenylate cyclase type 1(Human)
Food and Drug Administration

Curated by ChEMBL
LigandPNGBDBM50010274(CHEMBL328561 | Acetic acid (3R,4aR,5S,6S,6aS,10S,1...)
Affinity DataIC50: 31nMAssay Description:Inhibition of [125 I]6-IHPP-forskolin binding to adenylate cyclase 1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenylate cyclase type 1(Human)
Food and Drug Administration

Curated by ChEMBL
LigandPNGBDBM50052124(Acetic acid (3R,4aR,5S,6S,6aS,10S,10aR,10bS)-10,10...)
Affinity DataIC50: 32nMAssay Description:Inhibition of [125 I]6-IHPP-forskolin binding to adenylate cyclase 1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenylate cyclase type 1(Human)
Food and Drug Administration

Curated by ChEMBL
LigandPNGBDBM50052123(Acetic acid (3R,4aR,5S,6S,6aS,10S,10aR,10bS)-10,10...)
Affinity DataIC50: 36nMAssay Description:Inhibition of [125 I]6-IHPP-forskolin binding to adenylate cyclase 1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenylate cyclase type 1(Human)
Food and Drug Administration

Curated by ChEMBL
LigandPNGBDBM50052141(Acetic acid (3R,4aR,5S,6S,6aS,10S,10aR,10bS)-6-[2-...)
Affinity DataIC50: 39nMAssay Description:Inhibition of [125 I]6-IHPP-forskolin binding to adenylate cyclase 1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenylate cyclase type 1(Human)
Food and Drug Administration

Curated by ChEMBL
LigandPNGBDBM50010261(colforsinum | cid_47936 | colforsina | colforsine ...)
Affinity DataIC50: 41nMAssay Description:Inhibition of [125 I]6-IHPP-forskolin binding to adenylate cyclase 1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenylate cyclase type 1(Human)
Food and Drug Administration

Curated by ChEMBL
LigandPNGBDBM50052142((2-Hydroxy-ethyl)-carbamic acid (3R,4aR,5S,6S,6aS,...)
Affinity DataIC50: 43nMAssay Description:Inhibition of [125 I]6-IHPP-forskolin binding to adenylate cyclase 1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenylate cyclase type 1(Human)
Food and Drug Administration

Curated by ChEMBL
LigandPNGBDBM50052136(3-((3R,4aR,5S,6S,6aS,10S,10aR,10bS)-5-Acetoxy-10,1...)
Affinity DataIC50: 44nMAssay Description:Inhibition of [125 I]6-IHPP-forskolin binding to adenylate cyclase 1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenylate cyclase type 1(Human)
Food and Drug Administration

Curated by ChEMBL
LigandPNGBDBM50052143([2-(4-Amino-phenyl)-ethyl]-carbamic acid (3R,4aR,5...)
Affinity DataIC50: 64nMAssay Description:Inhibition of [125 I]6-IHPP-forskolin binding to adenylate cyclase 1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenylate cyclase type 1(Human)
Food and Drug Administration

Curated by ChEMBL
LigandPNGBDBM50052129(Phenethyl-carbamic acid (3R,4aR,5S,6S,6aS,10S,10aR...)
Affinity DataIC50: 65nMAssay Description:Inhibition of [125 I]6-IHPP-forskolin binding to adenylate cyclase 1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenylate cyclase type 1(Human)
Food and Drug Administration

Curated by ChEMBL
LigandPNGBDBM50052132(Acetic acid (3R,4aR,5S,6S,6aS,10S,10aR,10bS)-6-(2-...)
Affinity DataIC50: 73nMAssay Description:Inhibition of [125 I]6-IHPP-forskolin binding to adenylate cyclase 1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenylate cyclase type 1(Human)
Food and Drug Administration

Curated by ChEMBL
LigandPNGBDBM50052127(Acetic acid (3R,4aR,5S,6S,6aS,10S,10aR,10bS)-10,10...)
Affinity DataIC50: 76nMAssay Description:Inhibition of [125 I]6-IHPP-forskolin binding to adenylate cyclase 1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenylate cyclase type 1(Human)
Food and Drug Administration

Curated by ChEMBL
LigandPNGBDBM50052149(Acetic acid (3R,4aR,5S,6S,6aS,10S,10aR,10bS)-6-all...)
Affinity DataIC50: 76nMAssay Description:Inhibition of [125 I]6-IHPP-forskolin binding to adenylate cyclase 1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenylate cyclase type 1(Human)
Food and Drug Administration

Curated by ChEMBL
LigandPNGBDBM50052140(Acetic acid (3R,4aR,5S,6S,6aS,10S,10aR,10bS)-10,10...)
Affinity DataIC50: 82nMAssay Description:Inhibition of [125 I]6-IHPP-forskolin binding to adenylate cyclase 1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenylate cyclase type 1(Human)
Food and Drug Administration

Curated by ChEMBL
LigandPNGBDBM50052131(Propyl-carbamic acid (3R,4aR,5S,6S,6aS,10S,10aR,10...)
Affinity DataIC50: 89nMAssay Description:Inhibition of [125 I]6-IHPP-forskolin binding to adenylate cyclase 1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenylate cyclase type 1(Human)
Food and Drug Administration

Curated by ChEMBL
LigandPNGBDBM50010269(CHEMBL327672 | [2-(4-Hydroxy-phenyl)-ethyl]-carbam...)
Affinity DataIC50: 95nMAssay Description:Inhibition of [125 I]6-IHPP-forskolin binding to adenylate cyclase 1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenylate cyclase type 1(Human)
Food and Drug Administration

Curated by ChEMBL
LigandPNGBDBM50052116(Isobutyl-carbamic acid (3R,4aR,5S,6S,6aS,10S,10aR,...)
Affinity DataIC50: 112nMAssay Description:Inhibition of [125 I]6-IHPP-forskolin binding to adenylate cyclase 1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenylate cyclase type 1(Human)
Food and Drug Administration

Curated by ChEMBL
LigandPNGBDBM50052133(Acetic acid (3R,4aR,5S,6S,6aS,10S,10aR,10bS)-6-cyc...)
Affinity DataIC50: 117nMAssay Description:Inhibition of [125 I]6-IHPP-forskolin binding to adenylate cyclase 1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenylate cyclase type 1(Human)
Food and Drug Administration

Curated by ChEMBL
LigandPNGBDBM50052146((2-Pyridin-2-yl-ethyl)-carbamic acid (3R,4aR,5S,6S...)
Affinity DataIC50: 117nMAssay Description:Inhibition of [125 I]6-IHPP-forskolin binding to adenylate cyclase 1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenylate cyclase type 1(Human)
Food and Drug Administration

Curated by ChEMBL
LigandPNGBDBM50052148((2-Piperidin-1-yl-ethyl)-carbamic acid (3R,4aR,5S,...)
Affinity DataIC50: 123nMAssay Description:Inhibition of [125 I]6-IHPP-forskolin binding to adenylate cyclase 1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenylate cyclase type 1(Human)
Food and Drug Administration

Curated by ChEMBL
LigandPNGBDBM50010268(CHEMBL91909 | (2-Amino-ethyl)-carbamic acid (3R,4a...)
Affinity DataIC50: 128nMAssay Description:Inhibition of [125 I]6-IHPP-forskolin binding to adenylate cyclase 1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenylate cyclase type 1(Human)
Food and Drug Administration

Curated by ChEMBL
LigandPNGBDBM50052150(Acetic acid (3R,4aR,5S,6S,6aS,10S,10aR,10bS)-10,10...)
Affinity DataIC50: 142nMAssay Description:Inhibition of [125 I]6-IHPP-forskolin binding to adenylate cyclase 1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenylate cyclase type 1(Human)
Food and Drug Administration

Curated by ChEMBL
LigandPNGBDBM50052130((2-Pyridin-2-yl-ethyl)-carbamic acid (3R,4aR,5S,6S...)
Affinity DataIC50: 143nMAssay Description:Inhibition of [125 I]6-IHPP-forskolin binding to adenylate cyclase 1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenylate cyclase type 1(Human)
Food and Drug Administration

Curated by ChEMBL
LigandPNGBDBM50052111((2-Methoxy-ethyl)-carbamic acid (3R,4aR,5S,6S,6aS,...)
Affinity DataIC50: 150nMAssay Description:Inhibition of [125 I]6-IHPP-forskolin binding to adenylate cyclase 1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenylate cyclase type 1(Human)
Food and Drug Administration

Curated by ChEMBL
LigandPNGBDBM50010267([2-(4-Hydroxy-phenyl)-ethyl]-carbamic acid (3R,4aR...)
Affinity DataIC50: 150nMAssay Description:Inhibition of [125 I]6-IHPP-forskolin binding to adenylate cyclase 1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenylate cyclase type 1(Human)
Food and Drug Administration

Curated by ChEMBL
LigandPNGBDBM50052121(3-((3R,4aR,5S,6S,6aS,10S,10aR,10bS)-6,10,10b-Trihy...)
Affinity DataIC50: 150nMAssay Description:Inhibition of [125 I]6-IHPP-forskolin binding to adenylate cyclase 1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenylate cyclase type 1(Human)
Food and Drug Administration

Curated by ChEMBL
LigandPNGBDBM50052122(Acetic acid (3R,4aR,5S,6S,6aS,10S,10aR,10bS)-10,10...)
Affinity DataIC50: 150nMAssay Description:Inhibition of [125 I]6-IHPP-forskolin binding to adenylate cyclase 1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenylate cyclase type 1(Human)
Food and Drug Administration

Curated by ChEMBL
LigandPNGBDBM50052139(Allyl-carbamic acid (3R,4aR,5S,6S,6aS,10S,10aR,10b...)
Affinity DataIC50: 150nMAssay Description:Inhibition of [125 I]6-IHPP-forskolin binding to adenylate cyclase 1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenylate cyclase type 1(Human)
Food and Drug Administration

Curated by ChEMBL
LigandPNGBDBM50052120(Isobutyl-carbamic acid (3R,4aR,5S,6S,6aS,10S,10aR,...)
Affinity DataIC50: 150nMAssay Description:Inhibition of [125 I]6-IHPP-forskolin binding to adenylate cyclase 1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenylate cyclase type 1(Human)
Food and Drug Administration

Curated by ChEMBL
LigandPNGBDBM50052128(Cyclohexylmethyl-carbamic acid (3R,4aR,5S,6S,6aS,1...)
Affinity DataIC50: 150nMAssay Description:Inhibition of [125 I]6-IHPP-forskolin binding to adenylate cyclase 1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenylate cyclase type 1(Human)
Food and Drug Administration

Curated by ChEMBL
LigandPNGBDBM50052114(Phenethyl-carbamic acid (3R,4aR,5S,6S,6aS,10S,10aR...)
Affinity DataIC50: 150nMAssay Description:Inhibition of [125 I]6-IHPP-forskolin binding to adenylate cyclase 1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenylate cyclase type 1(Human)
Food and Drug Administration

Curated by ChEMBL
LigandPNGBDBM50052117(Cyclohexylmethyl-carbamic acid (3R,4aR,5S,6S,6aS,1...)
Affinity DataIC50: 150nMAssay Description:Inhibition of [125 I]6-IHPP-forskolin binding to adenylate cyclase 1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenylate cyclase type 1(Human)
Food and Drug Administration

Curated by ChEMBL
LigandPNGBDBM50052125(3-((3R,4aR,5S,6S,6aS,10S,10aR,10bS)-5,10,10b-Trihy...)
Affinity DataIC50: 150nMAssay Description:Inhibition of [125 I]6-IHPP-forskolin binding to adenylate cyclase 1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenylate cyclase type 1(Human)
Food and Drug Administration

Curated by ChEMBL
LigandPNGBDBM50052144((2-Hydroxy-ethyl)-carbamic acid (3R,4aR,5S,6S,6aS,...)
Affinity DataIC50: 150nMAssay Description:Inhibition of [125 I]6-IHPP-forskolin binding to adenylate cyclase 1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenylate cyclase type 1(Human)
Food and Drug Administration

Curated by ChEMBL
LigandPNGBDBM50052115((2-Dimethylamino-ethyl)-carbamic acid (3R,4aR,5S,6...)
Affinity DataIC50: 150nMAssay Description:Inhibition of [125 I]6-IHPP-forskolin binding to adenylate cyclase 1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenylate cyclase type 1(Human)
Food and Drug Administration

Curated by ChEMBL
LigandPNGBDBM50052135((2-Dimethylamino-ethyl)-carbamic acid (3R,4aR,5S,6...)
Affinity DataIC50: 150nMAssay Description:Inhibition of [125 I]6-IHPP-forskolin binding to adenylate cyclase 1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenylate cyclase type 1(Human)
Food and Drug Administration

Curated by ChEMBL
LigandPNGBDBM50052112((3,3-Dimethyl-butyl)-carbamic acid (3R,4aR,5S,6S,6...)
Affinity DataIC50: 150nMAssay Description:Inhibition of [125 I]6-IHPP-forskolin binding to adenylate cyclase 1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenylate cyclase type 1(Human)
Food and Drug Administration

Curated by ChEMBL
LigandPNGBDBM50052138(Allyl-carbamic acid (3R,4aR,5S,6S,6aS,10S,10aR,10b...)
Affinity DataIC50: 150nMAssay Description:Inhibition of [125 I]6-IHPP-forskolin binding to adenylate cyclase 1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenylate cyclase type 1(Human)
Food and Drug Administration

Curated by ChEMBL
LigandPNGBDBM50052145([2-(4-Amino-phenyl)-ethyl]-carbamic acid (3R,4aR,5...)
Affinity DataIC50: 150nMAssay Description:Inhibition of [125 I]6-IHPP-forskolin binding to adenylate cyclase 1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenylate cyclase type 1(Human)
Food and Drug Administration

Curated by ChEMBL
LigandPNGBDBM50052119((3,3-Dimethyl-butyl)-carbamic acid (3R,4aR,5S,6S,6...)
Affinity DataIC50: 150nMAssay Description:Inhibition of [125 I]6-IHPP-forskolin binding to adenylate cyclase 1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenylate cyclase type 1(Human)
Food and Drug Administration

Curated by ChEMBL
LigandPNGBDBM50052118(Propyl-carbamic acid (3R,4aR,5S,6S,6aS,10S,10aR,10...)
Affinity DataIC50: 150nMAssay Description:Inhibition of [125 I]6-IHPP-forskolin binding to Adenylate cyclase 1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenylate cyclase type 1(Human)
Food and Drug Administration

Curated by ChEMBL
LigandPNGBDBM50052113((2-Methoxy-ethyl)-carbamic acid (3R,4aR,5S,6S,6aS,...)
Affinity DataIC50: 150nMAssay Description:Inhibition of [125 I]6-IHPP-forskolin binding to adenylate cyclase 1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenylate cyclase type 1(Human)
Food and Drug Administration

Curated by ChEMBL
LigandPNGBDBM50052126((2-Piperidin-1-yl-ethyl)-carbamic acid (3R,4aR,5S,...)
Affinity DataIC50: 150nMAssay Description:Inhibition of [125 I]6-IHPP-forskolin binding to adenylate cyclase 1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenylate cyclase type 1(Human)
Food and Drug Administration

Curated by ChEMBL
LigandPNGBDBM50052133(Acetic acid (3R,4aR,5S,6S,6aS,10S,10aR,10bS)-6-cyc...)
Affinity DataIC50: 150nMAssay Description:Inhibition of [125 I]6-IHPP-forskolin binding to adenylate cyclase 1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenylate cyclase type 1(Human)
Food and Drug Administration

Curated by ChEMBL
LigandPNGBDBM50052138(Allyl-carbamic acid (3R,4aR,5S,6S,6aS,10S,10aR,10b...)
Affinity DataIC50: 157nMAssay Description:Inhibition of [125 I]6-IHPP-forskolin binding to adenylate cyclase 1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenylate cyclase type 1(Human)
Food and Drug Administration

Curated by ChEMBL
LigandPNGBDBM50052145([2-(4-Amino-phenyl)-ethyl]-carbamic acid (3R,4aR,5...)
Affinity DataIC50: 162nMAssay Description:Inhibition of [125 I]6-IHPP-forskolin binding to adenylate cyclase 1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenylate cyclase type 1(Human)
Food and Drug Administration

Curated by ChEMBL
LigandPNGBDBM50052122(Acetic acid (3R,4aR,5S,6S,6aS,10S,10aR,10bS)-10,10...)
Affinity DataIC50: 167nMAssay Description:Inhibition of [125 I]6-IHPP-forskolin binding to adenylate cyclase 1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenylate cyclase type 1(Human)
Food and Drug Administration

Curated by ChEMBL
LigandPNGBDBM50052125(3-((3R,4aR,5S,6S,6aS,10S,10aR,10bS)-5,10,10b-Trihy...)
Affinity DataIC50: 171nMAssay Description:Inhibition of [125 I]6-IHPP-forskolin binding to adenylate cyclase 1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
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