Compile Data Set for Download or QSAR
Report error Found 206 of ic50 data for polymerid = 50001761,50003780
TargetNon-lysosomal glucosylceramidase(Human)
Leiden University

Curated by ChEMBL
LigandPNGBDBM50028244(CHEMBL3354627)
Affinity DataIC50: 0.0800nMAssay Description:Inhibition of GBA2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNon-lysosomal glucosylceramidase(Human)
Leiden University

Curated by ChEMBL
LigandPNGBDBM50028179(CHEMBL3354624)
Affinity DataIC50: 0.0800nMAssay Description:Inhibition of GBA2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNon-lysosomal glucosylceramidase(Human)
Leiden University

Curated by ChEMBL
LigandPNGBDBM50028180(CHEMBL3354625)
Affinity DataIC50: 0.0800nMAssay Description:Inhibition of GBA2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNon-lysosomal glucosylceramidase(Human)
Leiden University

Curated by ChEMBL
LigandPNGBDBM50028254(CHEMBL3354634)
Affinity DataIC50: 0.100nMAssay Description:Inhibition of GBA2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNon-lysosomal glucosylceramidase(Human)
Leiden University

Curated by ChEMBL
LigandPNGBDBM50028255(CHEMBL3354635)
Affinity DataIC50: 0.100nMAssay Description:Inhibition of GBA2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNon-lysosomal glucosylceramidase(Human)
Leiden University

Curated by ChEMBL
LigandPNGBDBM50028181(CHEMBL3354626)
Affinity DataIC50: 0.120nMAssay Description:Inhibition of GBA2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNon-lysosomal glucosylceramidase(Human)
Leiden University

Curated by ChEMBL
LigandPNGBDBM50299749((2R,3R,4R,5S)-1-[5-(Adamantan-1-ylmethoxy)-pentyl]...)
Affinity DataIC50: 0.300nMAssay Description:Inhibition of non-lysosomal glucosylceramidase in cultured melanoma cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNon-lysosomal glucosylceramidase(Human)
Leiden University

Curated by ChEMBL
LigandPNGBDBM50028256(CHEMBL3354636)
Affinity DataIC50: 0.400nMAssay Description:Inhibition of GBA2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNon-lysosomal glucosylceramidase(Human)
Leiden University

Curated by ChEMBL
LigandPNGBDBM50335390(N-Hexoxypentyl-1-deoxynojirimycin | CHEMBL1651630)
Affinity DataIC50: 0.400nMAssay Description:Inhibition of NLGase in human SH-SY5Y cells using MUG-Gluc as fluorogenic substrate preincubated for 30 mins followed by substrate addition and measu...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNon-lysosomal glucosylceramidase(Human)
Leiden University

Curated by ChEMBL
LigandPNGBDBM50028221(CHEMBL3354041)
Affinity DataIC50: 0.5nMAssay Description:Inhibition of GBA2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNon-lysosomal glucosylceramidase(Human)
Leiden University

Curated by ChEMBL
LigandPNGBDBM50028257(CHEMBL3354637)
Affinity DataIC50: 0.600nMAssay Description:Inhibition of GBA2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNon-lysosomal glucosylceramidase(Human)
Leiden University

Curated by ChEMBL
LigandPNGBDBM50312527(N-[5-(Adamantan-1-yl-methoxy)-pentyl]-L-ido-1-deox...)
Affinity DataIC50: 1nMAssay Description:Inhibition of GBA2 by HPLCMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNon-lysosomal glucosylceramidase(Human)
Leiden University

Curated by ChEMBL
LigandPNGBDBM50312529(N-[5-(Adamantan-1-yl-methoxy)-pentyl]-D-galacto-1-...)
Affinity DataIC50: 1nMAssay Description:Inhibition of GBA2 by HPLCMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNon-lysosomal glucosylceramidase(Human)
Leiden University

Curated by ChEMBL
LigandPNGBDBM50028249(CHEMBL3354629)
Affinity DataIC50: 1nMAssay Description:Inhibition of GBA2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNon-lysosomal glucosylceramidase(Human)
Leiden University

Curated by ChEMBL
LigandPNGBDBM50312529(N-[5-(Adamantan-1-yl-methoxy)-pentyl]-D-galacto-1-...)
Affinity DataIC50: 1nMAssay Description:Inhibition of GBA2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNon-lysosomal glucosylceramidase(Human)
Leiden University

Curated by ChEMBL
LigandPNGBDBM50028176(CHEMBL3354621)
Affinity DataIC50: 1nMAssay Description:Inhibition of GBA2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNon-lysosomal glucosylceramidase(Human)
Leiden University

Curated by ChEMBL
LigandPNGBDBM50312527(N-[5-(Adamantan-1-yl-methoxy)-pentyl]-L-ido-1-deox...)
Affinity DataIC50: 1nMAssay Description:Inhibition of GBA2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNon-lysosomal glucosylceramidase(Human)
Leiden University

Curated by ChEMBL
LigandPNGBDBM50028188(CHEMBL3354019)
Affinity DataIC50: 1nMAssay Description:Inhibition of GBA2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNon-lysosomal glucosylceramidase(Human)
Leiden University

Curated by ChEMBL
LigandPNGBDBM50028203(CHEMBL3354021)
Affinity DataIC50: 1nMAssay Description:Inhibition of GBA2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNon-lysosomal glucosylceramidase(Human)
Leiden University

Curated by ChEMBL
LigandPNGBDBM50028204(CHEMBL3354022)
Affinity DataIC50: 1nMAssay Description:Inhibition of GBA2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNon-lysosomal glucosylceramidase(Human)
Leiden University

Curated by ChEMBL
LigandPNGBDBM50028215(CHEMBL3354035)
Affinity DataIC50: 1nMAssay Description:Inhibition of GBA2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNon-lysosomal glucosylceramidase(Human)
Leiden University

Curated by ChEMBL
LigandPNGBDBM50028217(CHEMBL3354037)
Affinity DataIC50: 1nMAssay Description:Inhibition of GBA2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNon-lysosomal glucosylceramidase(Human)
Leiden University

Curated by ChEMBL
LigandPNGBDBM50028229(CHEMBL3354048)
Affinity DataIC50: 1nMAssay Description:Inhibition of GBA2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNon-lysosomal glucosylceramidase(Human)
Leiden University

Curated by ChEMBL
LigandPNGBDBM50028230(CHEMBL3354049)
Affinity DataIC50: 1nMAssay Description:Inhibition of GBA2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNon-lysosomal glucosylceramidase(Human)
Leiden University

Curated by ChEMBL
LigandPNGBDBM50299749((2R,3R,4R,5S)-1-[5-(Adamantan-1-ylmethoxy)-pentyl]...)
Affinity DataIC50: 1nMAssay Description:Inhibition of human GBA2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNon-lysosomal glucosylceramidase(Human)
Leiden University

Curated by ChEMBL
LigandPNGBDBM50299749((2R,3R,4R,5S)-1-[5-(Adamantan-1-ylmethoxy)-pentyl]...)
Affinity DataIC50: 1nMAssay Description:Inhibition of GBA2 by HPLCMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNon-lysosomal glucosylceramidase(Human)
Leiden University

Curated by ChEMBL
LigandPNGBDBM50299749((2R,3R,4R,5S)-1-[5-(Adamantan-1-ylmethoxy)-pentyl]...)
Affinity DataIC50: 1nMAssay Description:Inhibition of recombinant GBA2 preincubated with compound for 30 mins using 4-methylumbelliferyl-B-glucoside substrate by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNon-lysosomal glucosylceramidase(Human)
Leiden University

Curated by ChEMBL
LigandPNGBDBM50299749((2R,3R,4R,5S)-1-[5-(Adamantan-1-ylmethoxy)-pentyl]...)
Affinity DataIC50: 1nMAssay Description:Inhibition of glucosylceramidase 2 from spleen of patient with gaucher's disease by fluorimetric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNon-lysosomal glucosylceramidase(Human)
Leiden University

Curated by ChEMBL
LigandPNGBDBM50524479(CHEMBL4459011)
Affinity DataIC50: 1nMAssay Description:Inhibition of NLGase in human SH-SY5Y cells using MUG-Gluc as fluorogenic substrate preincubated for 30 mins followed by substrate addition and measu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetNon-lysosomal glucosylceramidase(Human)
Leiden University

Curated by ChEMBL
LigandPNGBDBM50299749((2R,3R,4R,5S)-1-[5-(Adamantan-1-ylmethoxy)-pentyl]...)
Affinity DataIC50: 2nMAssay Description:Inhibition of non-lysosomal glucosylceramidaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNon-lysosomal glucosylceramidase(Human)
Leiden University

Curated by ChEMBL
LigandPNGBDBM50028235(CHEMBL3354054)
Affinity DataIC50: 2nMAssay Description:Inhibition of GBA2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNon-lysosomal glucosylceramidase(Human)
Leiden University

Curated by ChEMBL
LigandPNGBDBM50028173(CHEMBL3354063)
Affinity DataIC50: 2nMAssay Description:Inhibition of GBA2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNon-lysosomal glucosylceramidase(Human)
Leiden University

Curated by ChEMBL
LigandPNGBDBM50028248(CHEMBL3354628)
Affinity DataIC50: 2nMAssay Description:Inhibition of GBA2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNon-lysosomal glucosylceramidase(Human)
Leiden University

Curated by ChEMBL
LigandPNGBDBM50028251(CHEMBL3354631)
Affinity DataIC50: 2nMAssay Description:Inhibition of GBA2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNon-lysosomal glucosylceramidase(Human)
Leiden University

Curated by ChEMBL
LigandPNGBDBM50028252(CHEMBL3354632)
Affinity DataIC50: 2nMAssay Description:Inhibition of GBA2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNon-lysosomal glucosylceramidase(Human)
Leiden University

Curated by ChEMBL
LigandPNGBDBM50028253(CHEMBL3354633)
Affinity DataIC50: 2nMAssay Description:Inhibition of GBA2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNon-lysosomal glucosylceramidase(Human)
Leiden University

Curated by ChEMBL
LigandPNGBDBM50028258(CHEMBL3354638)
Affinity DataIC50: 2nMAssay Description:Inhibition of GBA2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNon-lysosomal glucosylceramidase(Human)
Leiden University

Curated by ChEMBL
LigandPNGBDBM50028214(CHEMBL3354032)
Affinity DataIC50: 2nMAssay Description:Inhibition of GBA2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNon-lysosomal glucosylceramidase(Human)
Leiden University

Curated by ChEMBL
LigandPNGBDBM50299749((2R,3R,4R,5S)-1-[5-(Adamantan-1-ylmethoxy)-pentyl]...)
Affinity DataIC50: 2nMAssay Description:Inhibition of GBA2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNon-lysosomal glucosylceramidase(Human)
Leiden University

Curated by ChEMBL
LigandPNGBDBM50028185(CHEMBL3354016)
Affinity DataIC50: 2nMAssay Description:Inhibition of GBA2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNon-lysosomal glucosylceramidase(Human)
Leiden University

Curated by ChEMBL
LigandPNGBDBM50028207(CHEMBL3354025)
Affinity DataIC50: 2nMAssay Description:Inhibition of GBA2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNon-lysosomal glucosylceramidase(Human)
Leiden University

Curated by ChEMBL
LigandPNGBDBM50028220(CHEMBL3354040)
Affinity DataIC50: 2nMAssay Description:Inhibition of GBA2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNon-lysosomal glucosylceramidase(Human)
Leiden University

Curated by ChEMBL
LigandPNGBDBM50028226(CHEMBL3354046)
Affinity DataIC50: 2nMAssay Description:Inhibition of GBA2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNon-lysosomal glucosylceramidase(Human)
Leiden University

Curated by ChEMBL
LigandPNGBDBM50028231(CHEMBL3354050)
Affinity DataIC50: 2nMAssay Description:Inhibition of GBA2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNon-lysosomal glucosylceramidase(Human)
Leiden University

Curated by ChEMBL
LigandPNGBDBM50028232(CHEMBL3354051)
Affinity DataIC50: 2nMAssay Description:Inhibition of GBA2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNon-lysosomal glucosylceramidase(Human)
Leiden University

Curated by ChEMBL
LigandPNGBDBM50242628(N-dodecyldeoxynojirimycin | CHEMBL450985)
Affinity DataIC50: 2nMAssay Description:Inhibition of bile acid beta-glucosidase activity of human liver GBA2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNon-lysosomal glucosylceramidase(Human)
Leiden University

Curated by ChEMBL
LigandPNGBDBM50028211(CHEMBL3354029)
Affinity DataIC50: 2.5nMAssay Description:Inhibition of GBA2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNon-lysosomal glucosylceramidase(Human)
Leiden University

Curated by ChEMBL
LigandPNGBDBM50028243(CHEMBL3354062)
Affinity DataIC50: 3nMAssay Description:Inhibition of GBA2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNon-lysosomal glucosylceramidase(Human)
Leiden University

Curated by ChEMBL
LigandPNGBDBM50028250(CHEMBL3354630)
Affinity DataIC50: 3nMAssay Description:Inhibition of GBA2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNon-lysosomal glucosylceramidase(Human)
Leiden University

Curated by ChEMBL
LigandPNGBDBM50028260(CHEMBL3354034)
Affinity DataIC50: 3nMAssay Description:Inhibition of GBA2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
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