Compile Data Set for Download or QSAR
Report error Found 525 of ic50 data for polymerid = 50001641,50007712
TargetHeparanase(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50614394(CHEMBL5273238)
Affinity DataIC50: 0.0800nMAssay Description:Inhibition of heparanase (unknown origin)More data for this Ligand-Target Pair
Ligand Info
In DepthDetails
PubMed
TargetHeparanase(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50614394(CHEMBL5273238)
Affinity DataIC50: 0.0800nMAssay Description:Inhibition of human heparanase using fondaparinux as substrate incubated for 18 hrs by Polymer-H fluorescence assayMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails
PubMed
TargetHeparanase(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50466629(CHEMBL4280766)
Affinity DataIC50: 5nMAssay Description:Inhibition of recombinant HPSE (unknown origin) using fondaparinux as substrate incubated for 3 hrs in absence of light by WST1 assayMore data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails Article
PubMed
TargetHeparanase(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50611959(CHEMBL5276024)
Affinity DataIC50: 5nMAssay Description:Inhibition of recombinant human heparanase incubated for 4 hrs by beta-scintillation counter analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetHeparanase(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50614397(CHEMBL5279386)
Affinity DataIC50: 12nMAssay Description:Inhibition of heparanase (unknown origin) incubated for 18 hrs by fondaparinux assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetHeparanase(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50612819(CHEMBL5291042)
Affinity DataIC50: 12nMAssay Description:Inhibition of recombinant human HPSE expressed in insect cells by fondaparinux assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetHeparanase(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50611973(CHEMBL5282692)
Affinity DataIC50: 12nMAssay Description:Inhibition of HPSE (unknown origin) using fondaparinux as substrate incubated for 18 hrs by fluorescence plate reader analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetHeparanase(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50093526(CHEMBL426373 | RK-682)
Affinity DataIC50: 17nMAssay Description:Inhibition of HPSE (unknown origin)More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetHeparanase(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50431651(CHEMBL2349236)
Affinity DataIC50: 17nMAssay Description:Inhibition of HPSE (unknown origin)More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetHeparanase(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50614398(CHEMBL5268939)
Affinity DataIC50: 20nMAssay Description:Inhibition of heparanase (unknown origin) incubated for 18 hrs by fondaparinux assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetHeparanase(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50612820(CHEMBL5267246)
Affinity DataIC50: 20nMAssay Description:Inhibition of recombinant human HPSE expressed in insect cells by fondaparinux assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetHeparanase(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50611974(CHEMBL5271999)
Affinity DataIC50: 20nMAssay Description:Inhibition of HPSE (unknown origin) using fondaparinux as substrate incubated for 18 hrs by fluorescence plate reader analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetHeparanase(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50175932(1,3-bis-[4-(5,6-dimethyl-1H-benzoimidazol-2-yl)phe...)
Affinity DataIC50: 75nMAssay Description:Inhibitory activity against heparanase from human plateletsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHeparanase(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50175932(1,3-bis-[4-(5,6-dimethyl-1H-benzoimidazol-2-yl)phe...)
Affinity DataIC50: 75nMAssay Description:Inhibition of recombinant heparanase catalytic stie (unknown origin) expressed in Escherichia coli BL21 (DE3)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHeparanase(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50466636(CHEMBL4286441)
Affinity DataIC50: 80nMAssay Description:Inhibition of recombinant HPSE (unknown origin) using fondaparinux as substrate incubated for 3 hrs in absence of light by WST1 assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetHeparanase(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50104680(3-Hexadecanoyl-5-hydroxymethyl-4-methoxy-5H-furan-...)
Affinity DataIC50: 100nMAssay Description:Inhibition of HPSE (unknown origin)More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetHeparanase(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50611970(CHEMBL5286960)
Affinity DataIC50: 100nMAssay Description:Inhibition of HPSE (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetHeparanase(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50618639(CHEMBL5432881)
Affinity DataIC50: 120nMAssay Description:Inhibition of heparanase (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetHeparanase(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50431662(CHEMBL2349246)
Affinity DataIC50: 130nMAssay Description:Inhibition of recombinant heparanase catalytic stie (unknown origin) expressed in Escherichia coli BL21 (DE3)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHeparanase(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50175938(1,3-bis(4-(7-methyl-1H-benzo[d]imidazol-2-yl)pheny...)
Affinity DataIC50: 150nMAssay Description:Inhibitory activity against heparanase from human plateletsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHeparanase(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50175936(1,3-bis(4-(6-methyl-1H-benzo[d]imidazol-2-yl)pheny...)
Affinity DataIC50: 150nMAssay Description:Inhibitory activity against heparanase from human plateletsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHeparanase(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50175931(1-(4-(1H-benzo[d]imidazol-2-yl)phenyl)-3-(4-(7-met...)
Affinity DataIC50: 150nMAssay Description:Inhibitory activity against heparanase from human plateletsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHeparanase(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50506597(CHEMBL4576477)
Affinity DataIC50: 160nMAssay Description:Inhibition of recombinant HPSE GS3 (unknown origin) using fondaparinux as substrate incubated for 3 hrs in absence of light by WST1 based colorimetryMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetHeparanase(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50466651(CHEMBL4283251)
Affinity DataIC50: 180nMAssay Description:Inhibition of recombinant HPSE (unknown origin) using fondaparinux as substrate incubated for 3 hrs in absence of light by WST1 assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetHeparanase(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50147546(2-[3-(5-Benzo[1,3]dioxol-5-yl-benzooxazol-2-yl)-4-...)
Affinity DataIC50: 200nMAssay Description:In vivo inhibitory activity against human HeparanaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHeparanase(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50147513(2-[3-[5-(4-Chloro-phenyl)-benzooxazol-2-yl]-4-(2-m...)
Affinity DataIC50: 200nMAssay Description:In vivo inhibitory activity against human HeparanaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHeparanase(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50165639(2-(2-(4-(3-(2,4-dichlorophenylamino)-3-oxoprop-1-e...)
Affinity DataIC50: 200nMAssay Description:In vitro inhibitory concentration against human HeparanaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHeparanase(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50165660(2-(3-(5-(4-chlorophenyl)benzo[d]oxazol-2-yl)-4-(pr...)
Affinity DataIC50: 200nMAssay Description:In vitro inhibitory concentration against human HeparanaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHeparanase(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50165653(2-(2-(4-(3-(3,4-dichlorophenylamino)-3-oxoprop-1-e...)
Affinity DataIC50: 200nMAssay Description:In vitro inhibitory concentration against human HeparanaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHeparanase(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50165669(2-(2-(4-(3-(3-bromophenylamino)-3-oxoprop-1-enyl)-...)
Affinity DataIC50: 200nMAssay Description:In vitro inhibitory concentration against human HeparanaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHeparanase(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50431663(CHEMBL2349247)
Affinity DataIC50: 200nMAssay Description:Inhibition of recombinant heparanase catalytic stie (unknown origin) expressed in Escherichia coli BL21 (DE3)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHeparanase(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50165660(2-(3-(5-(4-chlorophenyl)benzo[d]oxazol-2-yl)-4-(pr...)
Affinity DataIC50: 200nMAssay Description:Inhibition of recombinant heparanase catalytic stie (unknown origin) expressed in Escherichia coli BL21 (DE3)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHeparanase(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50165639(2-(2-(4-(3-(2,4-dichlorophenylamino)-3-oxoprop-1-e...)
Affinity DataIC50: 200nMAssay Description:Inhibition of heparanaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHeparanase(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50165669(2-(2-(4-(3-(3-bromophenylamino)-3-oxoprop-1-enyl)-...)
Affinity DataIC50: 200nMAssay Description:Inhibition of heparanaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHeparanase(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50165660(2-(3-(5-(4-chlorophenyl)benzo[d]oxazol-2-yl)-4-(pr...)
Affinity DataIC50: 200nMAssay Description:Inhibition of heparanaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHeparanase(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50165653(2-(2-(4-(3-(3,4-dichlorophenylamino)-3-oxoprop-1-e...)
Affinity DataIC50: 200nMAssay Description:Inhibition of heparanaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHeparanase(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50147546(2-[3-(5-Benzo[1,3]dioxol-5-yl-benzooxazol-2-yl)-4-...)
Affinity DataIC50: 200nMAssay Description:Inhibition of heparanaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHeparanase(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50147546(2-[3-(5-Benzo[1,3]dioxol-5-yl-benzooxazol-2-yl)-4-...)
Affinity DataIC50: 200nMAssay Description:Inhibition of human recombinant HeparanaseMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetHeparanase(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50165660(2-(3-(5-(4-chlorophenyl)benzo[d]oxazol-2-yl)-4-(pr...)
Affinity DataIC50: 200nMAssay Description:Inhibition of human recombinant HeparanaseMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetHeparanase(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50165639(2-(2-(4-(3-(2,4-dichlorophenylamino)-3-oxoprop-1-e...)
Affinity DataIC50: 200nMAssay Description:Inhibition of heparanase (unknown origin)More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetHeparanase(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50614402(CHEMBL5285151)
Affinity DataIC50: 200nMAssay Description:Inhibition of human heparanase assessed as reduction in basic fibroblast growth factor binding incubated for 2 hrs by microplate reader assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetHeparanase(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50412102(CHEMBL495255)
Affinity DataIC50: 200nMAssay Description:Inhibition of human heparanase assessed as reduction in basic fibroblast growth factor binding incubated for 2 hrs by microplate reader assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetHeparanase(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50147546(2-[3-(5-Benzo[1,3]dioxol-5-yl-benzooxazol-2-yl)-4-...)
Affinity DataIC50: 200nMAssay Description:Inhibition of human heparanase assessed as reduction in basic fibroblast growth factor binding incubated for 2 hrs by microplate reader assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetHeparanase(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50147546(2-[3-(5-Benzo[1,3]dioxol-5-yl-benzooxazol-2-yl)-4-...)
Affinity DataIC50: 200nMAssay Description:Inhibition of human HPSE incubated for 2 hrs using TMB peroxidase as substrate by microplate reader analysisMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetHeparanase(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50611966(CHEMBL5277782)
Affinity DataIC50: 200nMAssay Description:Inhibition of human HPSE incubated for 2 hrs using TMB peroxidase as substrate by microplate reader analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetHeparanase(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50175811(N-(4-{[4-(1H-benzoimidazol-2-yl)phenylamino]methyl...)
Affinity DataIC50: 230nMAssay Description:Inhibitory activity against heparanase from human plateletsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHeparanase(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50175811(N-(4-{[4-(1H-benzoimidazol-2-yl)phenylamino]methyl...)
Affinity DataIC50: 230nMAssay Description:Inhibition of recombinant heparanase catalytic stie (unknown origin) expressed in Escherichia coli BL21 (DE3)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHeparanase(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50611968(CHEMBL5266599)
Affinity DataIC50: 230nMAssay Description:Inhibition of HPSE (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetHeparanase(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50147534(1,3-dioxo-2-(3-(5-phenylbenzo[d]oxazol-2-yl)-4-(pr...)
Affinity DataIC50: 250nMAssay Description:In vivo inhibitory activity against human HeparanaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHeparanase(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50375289(CHEMBL258980)
Affinity DataIC50: 250nMAssay Description:Inhibition of human platelet heparanaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
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