Compile Data Set for Download or QSAR
Report error Found 168 of ic50 data for polymerid = 50001533
TargetCocaine esterase(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50409669(CHEMBL155514)
Affinity DataIC50: 0.178nMAssay Description:In vitro inhibition of carboxylesterase in human liver microsomes.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCocaine esterase(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50409660(CHEMBL155513)
Affinity DataIC50: 3.39nMAssay Description:In vitro inhibition of carboxylesterase in human liver microsomes.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCocaine esterase(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50570553(CHEMBL4854298)
Affinity DataIC50: 4nMAssay Description:Inhibition of human recombinant CES2 expressed in mouse NSO cells using 4-NPA as substrate by spectrophotometric analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetCocaine esterase(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50570549(CHEMBL4853742)
Affinity DataIC50: 4.30nMAssay Description:Inhibition of human recombinant CES2 expressed in mouse NSO cells using 4-NPA as substrate by spectrophotometric analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetCocaine esterase(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50409672(CHEMBL153080)
Affinity DataIC50: 5.5nMAssay Description:In vitro inhibition of carboxylesterase in human liver microsomes.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCocaine esterase(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50371970(CHEMBL89506)
Affinity DataIC50: 5.80nMAssay Description:Inhibition of human recombinant carboxylesterase 2 after 15 minsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCocaine esterase(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50371971(CHEMBL440542)
Affinity DataIC50: 6.92nMAssay Description:In vitro inhibition of carboxylesterase in human liver microsomes.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCocaine esterase(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50371961(CHEMBL270373)
Affinity DataIC50: 7.40nMAssay Description:Inhibition of human recombinant carboxylesterase 2 after 15 minsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCocaine esterase(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50371970(CHEMBL89506)
Affinity DataIC50: 8.5nMAssay Description:Inhibition of human recombinant carboxylesterase 2 after 5 minsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCocaine esterase(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50570554(CHEMBL4858186)
Affinity DataIC50: 9.80nMAssay Description:Inhibition of human recombinant CES2 expressed in mouse NSO cells using 4-NPA as substrate by spectrophotometric analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetCocaine esterase(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50371961(CHEMBL270373)
Affinity DataIC50: 11nMAssay Description:Inhibition of human recombinant carboxylesterase 2 after 5 minsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCocaine esterase(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50570555(CHEMBL4868014)
Affinity DataIC50: 11nMAssay Description:Inhibition of human recombinant CES2 expressed in mouse NSO cells using 4-NPA as substrate by spectrophotometric analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetCocaine esterase(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50570561(CHEMBL4855838)
Affinity DataIC50: 17nMAssay Description:Inhibition of human recombinant CES2 expressed in mouse NSO cells using 4-NPA as substrate by spectrophotometric analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetCocaine esterase(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50154561(CHEMBL3774603)
Affinity DataIC50: 20nMAssay Description:Inhibition of CE2 in human liver microsomes using fluorescein diacetate as substrate preincubated for 10 mins followed by substrate addition measured...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCocaine esterase(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50371959(CHEMBL86668)
Affinity DataIC50: 20nMAssay Description:Inhibition of human recombinant carboxylesterase 2 after 15 minsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCocaine esterase(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50371964(CHEMBL273139)
Affinity DataIC50: 21nMAssay Description:Inhibition of human recombinant carboxylesterase 2 after 15 minsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCocaine esterase(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50570551(CHEMBL4853637)
Affinity DataIC50: 23nMAssay Description:Inhibition of human recombinant CES2 expressed in mouse NSO cells using 4-NPA as substrate by spectrophotometric analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetCocaine esterase(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50371964(CHEMBL273139)
Affinity DataIC50: 26nMAssay Description:Inhibition of human recombinant carboxylesterase 2 after 5 minsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCocaine esterase(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50409657(CHEMBL153015)
Affinity DataIC50: 32.4nMAssay Description:In vitro inhibition of carboxylesterase in human liver microsomes.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCocaine esterase(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50371959(CHEMBL86668)
Affinity DataIC50: 36nMAssay Description:Inhibition of human recombinant carboxylesterase 2 after 5 minsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCocaine esterase(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM22722(1,2-diphenylethane-1,2-dione | Diphenylethane-1,2-...)
Affinity DataIC50: 38nMAssay Description:Inhibition of human recombinant carboxylesterase 2 after 5 minsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCocaine esterase(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM22722(1,2-diphenylethane-1,2-dione | Diphenylethane-1,2-...)
Affinity DataIC50: 44nMAssay Description:Inhibition of human recombinant carboxylesterase 2 after 15 minsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCocaine esterase(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50371960(CHEMBL155621)
Affinity DataIC50: 46.8nMAssay Description:In vitro inhibition of carboxylesterase in human liver microsomes.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCocaine esterase(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50409670(CHEMBL421992)
Affinity DataIC50: 47.9nMAssay Description:In vitro inhibition of carboxylesterase in human liver microsomes.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCocaine esterase(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50570558(CHEMBL4849436)
Affinity DataIC50: 48nMAssay Description:Inhibition of human recombinant CES2 expressed in mouse NSO cells using 4-NPA as substrate by spectrophotometric analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetCocaine esterase(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50552232(CHEMBL4776624)
Affinity DataIC50: 52nMAssay Description:Inhibition of hCES2A in human liver microsome assessed as reduction in fluorescein diacetate hydrolysis preincubated for 10 mins followed by substrat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetCocaine esterase(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50570552(CHEMBL4855755)
Affinity DataIC50: 71nMAssay Description:Inhibition of human recombinant CES2 expressed in mouse NSO cells using 4-NPA as substrate by spectrophotometric analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetCocaine esterase(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50570550(CHEMBL4849361)
Affinity DataIC50: 72nMAssay Description:Inhibition of human recombinant CES2 expressed in mouse NSO cells using 4-NPA as substrate by spectrophotometric analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetCocaine esterase(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50409658(CHEMBL153177)
Affinity DataIC50: 100nMAssay Description:In vitro inhibition of carboxylesterase in human liver microsomes.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCocaine esterase(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50571105(CHEMBL4851375)
Affinity DataIC50: 130nMAssay Description:Inhibition of CES2 in human liver microsomes assessed as reduction in substrate hydrolysis using fluorescein diacetate as substrate preincubated for ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetCocaine esterase(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50570559(CHEMBL4868687)
Affinity DataIC50: 193nMAssay Description:Inhibition of human recombinant CES2 expressed in mouse NSO cells using 4-NPA as substrate by spectrophotometric analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetCocaine esterase(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50570566(CHEMBL4849604)
Affinity DataIC50: 230nMAssay Description:Inhibition of human recombinant CES2 expressed in mouse NSO cells using 4-NPA as substrate by spectrophotometric analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetCocaine esterase(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50505364(CHEMBL4460898)
Affinity DataIC50: 260nMAssay Description:Inhibition of CES2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCocaine esterase(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50371962(CHEMBL155396)
Affinity DataIC50: 309nMAssay Description:In vitro inhibition of carboxylesterase in human liver microsomes.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCocaine esterase(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50570560(CHEMBL4872772)
Affinity DataIC50: 339nMAssay Description:Inhibition of human recombinant CES2 expressed in mouse NSO cells using 4-NPA as substrate by spectrophotometric analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetCocaine esterase(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50552233(CHEMBL4748399)
Affinity DataIC50: 380nMAssay Description:Inhibition of hCES2A in human liver microsome assessed as reduction in fluorescein diacetate hydrolysis preincubated for 10 mins followed by substrat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetCocaine esterase(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50552231(CHEMBL4740149)
Affinity DataIC50: 610nMAssay Description:Inhibition of hCES2A in human liver microsome assessed as reduction in fluorescein diacetate hydrolysis preincubated for 10 mins followed by substrat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetCocaine esterase(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50570564(CHEMBL4853013)
Affinity DataIC50: 610nMAssay Description:Inhibition of human recombinant CES2 expressed in mouse NSO cells using 4-NPA as substrate by spectrophotometric analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetCocaine esterase(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50556551(CHEMBL4780848)
Affinity DataIC50: 630nMAssay Description:Inhibition of hCES2A in human liver microsome assessed as reduction in fluorescein diacetate hydrolysis preincubated for 10 mins followed by substrat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetCocaine esterase(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50154559(CHEMBL2151605)
Affinity DataIC50: 660nMAssay Description:Inhibition of CE2 in human liver microsomes using fluorescein diacetate as substrate preincubated for 10 mins followed by substrate addition measured...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCocaine esterase(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50556550(CHEMBL4748929)
Affinity DataIC50: 810nMAssay Description:Inhibition of hCES2A in human liver microsome assessed as reduction in fluorescein diacetate hydrolysis preincubated for 10 mins followed by substrat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetCocaine esterase(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50552214(CHEMBL4747287)
Affinity DataIC50: 1.09E+3nMAssay Description:Inhibition of hCES2A in human liver microsome assessed as reduction in fluorescein diacetate hydrolysis preincubated for 10 mins followed by substrat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetCocaine esterase(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50552212(CHEMBL4761197)
Affinity DataIC50: 1.31E+3nMAssay Description:Inhibition of hCES2A in human liver microsome assessed as reduction in fluorescein diacetate hydrolysis preincubated for 10 mins followed by substrat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetCocaine esterase(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50552215(CHEMBL4751728)
Affinity DataIC50: 1.48E+3nMAssay Description:Inhibition of hCES2A in human liver microsome assessed as reduction in fluorescein diacetate hydrolysis preincubated for 10 mins followed by substrat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetCocaine esterase(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50233165(CHEMBL1222042)
Affinity DataIC50: 1.57E+3nMAssay Description:Inhibition of CES2 in human liver microsomes assessed as reduction in substrate hydrolysis using fluorescein diacetate as substrate preincubated for ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCocaine esterase(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50552229(CHEMBL4752404)
Affinity DataIC50: 1.62E+3nMAssay Description:Inhibition of hCES2A in human liver microsome assessed as reduction in fluorescein diacetate hydrolysis preincubated for 10 mins followed by substrat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetCocaine esterase(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50553890(CHEMBL4756952)
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of CES2A1 in human liver microsomes using D-luciferin methyl ester as substrate preincubated for 10 mins followed by substrate addition an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetCocaine esterase(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50553891(CHEMBL4763518)
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of CES2A1 in human liver microsomes using D-luciferin methyl ester as substrate preincubated for 10 mins followed by substrate addition an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetCocaine esterase(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50553892(CHEMBL4798331)
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of CES2A1 in human liver microsomes using D-luciferin methyl ester as substrate preincubated for 10 mins followed by substrate addition an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetCocaine esterase(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50553893(CHEMBL4759191)
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of CES2A1 in human liver microsomes using D-luciferin methyl ester as substrate preincubated for 10 mins followed by substrate addition an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
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