Compile Data Set for Download or QSAR
Report error Found 52 of ic50 data for polymerid = 50001170
TargetMatrix metalloproteinase-16(Human)
Instituto Superior TéCnico

Curated by ChEMBL
LigandPNGBDBM50246599(N-(4-Phenoxybenzenesulfonyl)-N-{[2-(4-sulfamoylphe...)
Affinity DataIC50: 0.310nMAssay Description:Inhibition of MMP16More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMatrix metalloproteinase-16(Human)
Instituto Superior TéCnico

Curated by ChEMBL
LigandPNGBDBM50241252(2-[hydroxycarbamoylmethyl-(4-phenoxy-benzenesulfon...)
Affinity DataIC50: 1nMAssay Description:Inhibition of MMP16More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMatrix metalloproteinase-16(Human)
Instituto Superior TéCnico

Curated by ChEMBL
LigandPNGBDBM50273426(N-(4-Phenoxybenzenesulfonyl)-N-hydroxycarbonylmeth...)
Affinity DataIC50: 1.60nMAssay Description:Inhibition of MMP16More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMatrix metalloproteinase-16(Human)
Instituto Superior TéCnico

Curated by ChEMBL
LigandPNGBDBM50066658((R)-N-Hydroxy-2-[(4-methoxy-benzenesulfonyl)-pyrid...)
Affinity DataIC50: 6.80nMAssay Description:Inhibition of MMP16More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMatrix metalloproteinase-16(Human)
Instituto Superior TéCnico

Curated by ChEMBL
LigandPNGBDBM50062351((R)-N*4*-Hydroxy-N*1*-[2-(1H-indol-3-yl)-1-methylc...)
Affinity DataIC50: 8nMAssay Description:Inhibition of matrix metalloprotease-16 (MMP-16)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMatrix metalloproteinase-16(Human)
Instituto Superior TéCnico

Curated by ChEMBL
LigandPNGBDBM50062351((R)-N*4*-Hydroxy-N*1*-[2-(1H-indol-3-yl)-1-methylc...)
Affinity DataIC50: 8nMAssay Description:Inhibitory activity against MMP16More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMatrix metalloproteinase-16(Human)
Instituto Superior TéCnico

Curated by ChEMBL
LigandPNGBDBM50246601(2-(N-(2-(hydroxyamino)-2-oxoethyl)-4-phenoxyphenyl...)
Affinity DataIC50: 11nMAssay Description:Inhibition of MMP16More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMatrix metalloproteinase-16(Human)
Instituto Superior TéCnico

Curated by ChEMBL
LigandPNGBDBM50137276(6-Hydroxy-7-methoxy-2-(4-methoxy-benzenesulfonyl)-...)
Affinity DataIC50: 16nMAssay Description:Inhibition of matrix metalloprotease-16 (MMP-16)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMatrix metalloproteinase-16(Human)
Instituto Superior TéCnico

Curated by ChEMBL
LigandPNGBDBM50137282(6-Hydroxy-2-(toluene-4-sulfonyl)-1,2,3,4-tetrahydr...)
Affinity DataIC50: 21nMAssay Description:Inhibition of matrix metalloprotease-16 (MMP-16)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMatrix metalloproteinase-16(Human)
Instituto Superior TéCnico

Curated by ChEMBL
LigandPNGBDBM50137283(6-Benzyloxy-2-(4-methoxy-benzenesulfonyl)-1,2,3,4-...)
Affinity DataIC50: 22nMAssay Description:Inhibition of matrix metalloprotease-16 (MMP-16)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMatrix metalloproteinase-16(Human)
Instituto Superior TéCnico

Curated by ChEMBL
LigandPNGBDBM50299051(N-Hydroxy-2-{2-[4-(4-methoxy-phenoxy)benzenesulfon...)
Affinity DataIC50: 32nMAssay Description:Inhibition of human recombinant pro-MMP16 catalytic domain after 4 hrs by fluorimetryMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMatrix metalloproteinase-16(Human)
Instituto Superior TéCnico

Curated by ChEMBL
LigandPNGBDBM50137287(6-(benzyloxy)-N-hydroxy-2-(phenylsulfonyl)-1,2,3,4...)
Affinity DataIC50: 35nMAssay Description:Inhibition of matrix metalloprotease-16 (MMP-16)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMatrix metalloproteinase-16(Human)
Instituto Superior TéCnico

Curated by ChEMBL
LigandPNGBDBM50361601(CHEMBL1939846)
Affinity DataIC50: 39nMAssay Description:Inhibition of human recombinant MMP16 using Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 as substrate preincubated for 4 hrs measured every 15 secs f...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMatrix metalloproteinase-16(Human)
Instituto Superior TéCnico

Curated by ChEMBL
LigandPNGBDBM50137281(N,6-dihydroxy-7-methoxy-2-(phenylsulfonyl)-1,2,3,4...)
Affinity DataIC50: 40nMAssay Description:Inhibition of matrix metalloprotease-16 (MMP-16)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMatrix metalloproteinase-16(Human)
Instituto Superior TéCnico

Curated by ChEMBL
LigandPNGBDBM50241251(N-(4-Methoxybenzenesulfonyl)-N-{[2-(4-sulfamoylphe...)
Affinity DataIC50: 44nMAssay Description:Inhibition of MMP16More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMatrix metalloproteinase-16(Human)
Instituto Superior TéCnico

Curated by ChEMBL
LigandPNGBDBM50294132(N-hydroxy-2-(N-isopropoxy-4'-isopropylbiphenyl-4-y...)
Affinity DataIC50: 51nMAssay Description:Inhibition of human recombinant MMP16More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMatrix metalloproteinase-16(Human)
Instituto Superior TéCnico

Curated by ChEMBL
LigandPNGBDBM50161330((R)-2-[(Biphenyl-4-sulfonyl)-isopropoxy-amino]-N-h...)
Affinity DataIC50: 51nMAssay Description:Inhibition of human recombinant pro-MMP16 catalytic domain after 4 hrs by fluorimetryMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMatrix metalloproteinase-16(Human)
Instituto Superior TéCnico

Curated by ChEMBL
LigandPNGBDBM50137285(6-Benzyloxy-2-(toluene-4-sulfonyl)-1,2,3,4-tetrahy...)
Affinity DataIC50: 56nMAssay Description:Inhibition of matrix metalloprotease-16 (MMP-16)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMatrix metalloproteinase-16(Human)
Instituto Superior TéCnico

Curated by ChEMBL
LigandPNGBDBM50299053(N-Hydroxy-2-(2-(4-methoxyphenylsulfonyl)phenyl)ace...)
Affinity DataIC50: 130nMAssay Description:Inhibition of human recombinant pro-MMP16 catalytic domain after 4 hrs by fluorimetryMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMatrix metalloproteinase-16(Human)
Instituto Superior TéCnico

Curated by ChEMBL
LigandPNGBDBM50299052(N-Hydroxy-2-[2-(4'-methoxy-biphenyl-4-sulfonyl)phe...)
Affinity DataIC50: 130nMAssay Description:Inhibition of human recombinant pro-MMP16 catalytic domain after 4 hrs by fluorimetryMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMatrix metalloproteinase-16(Human)
Instituto Superior TéCnico

Curated by ChEMBL
LigandPNGBDBM50299056((+/-)-N-Hydroxy-2-[2-(4'-methoxy-biphenyl-4-sulfon...)
Affinity DataIC50: 150nMAssay Description:Inhibition of human recombinant pro-MMP16 catalytic domain after 4 hrs by fluorimetryMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMatrix metalloproteinase-16(Human)
Instituto Superior TéCnico

Curated by ChEMBL
LigandPNGBDBM50137279(6-Hydroxy-2-(4-nitro-benzenesulfonyl)-1,2,3,4-tetr...)
Affinity DataIC50: 177nMAssay Description:Inhibition of matrix metalloprotease-16 (MMP-16)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMatrix metalloproteinase-16(Human)
Instituto Superior TéCnico

Curated by ChEMBL
LigandPNGBDBM50137284(2-Benzenesulfonyl-6-hydroxy-1,2,3,4-tetrahydro-iso...)
Affinity DataIC50: 184nMAssay Description:Inhibition of matrix metalloprotease-16 (MMP-16)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMatrix metalloproteinase-16(Human)
Instituto Superior TéCnico

Curated by ChEMBL
LigandPNGBDBM50241253(2-[(biphenyl-4-sulfonyl)-hydroxycarbamoylmethyl-am...)
Affinity DataIC50: 186nMAssay Description:Inhibition of MMP16More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMatrix metalloproteinase-16(Human)
Instituto Superior TéCnico

Curated by ChEMBL
LigandPNGBDBM50137277(2-(4-Amino-benzenesulfonyl)-6-hydroxy-1,2,3,4-tetr...)
Affinity DataIC50: 202nMAssay Description:Inhibition of matrix metalloprotease-16 (MMP-16)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMatrix metalloproteinase-16(Human)
Instituto Superior TéCnico

Curated by ChEMBL
LigandPNGBDBM50299054(2-[2-(Biphenyl-4-sulfonyl)phenyl]N-hydroxy-acetami...)
Affinity DataIC50: 220nMAssay Description:Inhibition of human recombinant pro-MMP16 catalytic domain after 4 hrs by fluorimetryMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMatrix metalloproteinase-16(Human)
Instituto Superior TéCnico

Curated by ChEMBL
LigandPNGBDBM50299058((+/-)-2-[2-(Biphenyl-4-sulfonyl)phenyl]N-hydroxy-p...)
Affinity DataIC50: 470nMAssay Description:Inhibition of human recombinant pro-MMP16 catalytic domain after 4 hrs by fluorimetryMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMatrix metalloproteinase-16(Human)
Instituto Superior TéCnico

Curated by ChEMBL
LigandPNGBDBM50299055([2-(4'-Methoxy-biphenyl-4-sulfonyl)phenyl]acetic A...)
Affinity DataIC50: 730nMAssay Description:Inhibition of human recombinant pro-MMP16 catalytic domain after 4 hrs by fluorimetryMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMatrix metalloproteinase-16(Human)
Instituto Superior TéCnico

Curated by ChEMBL
LigandPNGBDBM50161331(2-[(Biphenyl-4-sulfonyl)-isopropoxy-amino]-N-hydro...)
Affinity DataIC50: 900nMAssay Description:Inhibition of human recombinant MMP16More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMatrix metalloproteinase-16(Human)
Instituto Superior TéCnico

Curated by ChEMBL
LigandPNGBDBM50246600(2-(N-(2-(hydroxyamino)-2-oxoethyl)-4-methoxyphenyl...)
Affinity DataIC50: 996nMAssay Description:Inhibition of MMP16More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMatrix metalloproteinase-16(Human)
Instituto Superior TéCnico

Curated by ChEMBL
LigandPNGBDBM50299060((+/-)-2-[2-(4'-Methoxy-biphenyl-4-sulfonyl)phenyl]...)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of human recombinant pro-MMP16 catalytic domain after 4 hrs by fluorimetryMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMatrix metalloproteinase-16(Human)
Instituto Superior TéCnico

Curated by ChEMBL
LigandPNGBDBM50361599(CHEMBL1939844)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of human recombinant MMP16 using Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 as substrate preincubated for 4 hrs measured every 15 secs f...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMatrix metalloproteinase-16(Human)
Instituto Superior TéCnico

Curated by ChEMBL
LigandPNGBDBM50299059(N-Hydroxy-2-(4'-methoxybiphenyl-4-ylsulfonyl)benza...)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of human recombinant pro-MMP16 catalytic domain after 4 hrs by fluorimetryMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMatrix metalloproteinase-16(Human)
Instituto Superior TéCnico

Curated by ChEMBL
LigandPNGBDBM50299065(N-Hydroxy-2-(4-phenoxy-benzenesulfonyl)benzamide |...)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of human recombinant pro-MMP16 catalytic domain after 4 hrs by fluorimetryMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMatrix metalloproteinase-16(Human)
Instituto Superior TéCnico

Curated by ChEMBL
LigandPNGBDBM50137286(6-Hydroxy-2-(4-methoxy-benzenesulfonyl)-1,2,3,4-te...)
Affinity DataIC50: 1.68E+3nMAssay Description:Inhibition of matrix metalloprotease-16 (MMP-16)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMatrix metalloproteinase-16(Human)
Instituto Superior TéCnico

Curated by ChEMBL
LigandPNGBDBM50137278(2-(2,5-Dichloro-benzenesulfonyl)-6-hydroxy-1,2,3,4...)
Affinity DataIC50: 1.84E+3nMAssay Description:Inhibition of MMP-16 (unknown origin) expressed in Escherichia coli BL21(DE3) and measured for 2 mins by enzymatic assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetMatrix metalloproteinase-16(Human)
Instituto Superior TéCnico

Curated by ChEMBL
LigandPNGBDBM50137278(2-(2,5-Dichloro-benzenesulfonyl)-6-hydroxy-1,2,3,4...)
Affinity DataIC50: 1.84E+3nMAssay Description:Inhibition of matrix metalloprotease-16 (MMP-16)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMatrix metalloproteinase-16(Human)
Instituto Superior TéCnico

Curated by ChEMBL
LigandPNGBDBM50361600(CHEMBL1939845)
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of human recombinant MMP16 using Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 as substrate preincubated for 4 hrs measured every 15 secs f...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMatrix metalloproteinase-16(Human)
Instituto Superior TéCnico

Curated by ChEMBL
LigandPNGBDBM50299061([2-(Biphenyl-4-sulfonyl)phenyl]acetic Acid | CHEMB...)
Affinity DataIC50: 4.30E+3nMAssay Description:Inhibition of human recombinant pro-MMP16 catalytic domain after 4 hrs by fluorimetryMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMatrix metalloproteinase-16(Human)
Instituto Superior TéCnico

Curated by ChEMBL
LigandPNGBDBM50137280(6-Benzyloxy-2-(2,5-dichloro-benzenesulfonyl)-1,2,3...)
Affinity DataIC50: 4.63E+3nMAssay Description:Inhibition of matrix metalloprotease-16 (MMP-16)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMatrix metalloproteinase-16(Human)
Instituto Superior TéCnico

Curated by ChEMBL
LigandPNGBDBM50294131((R)-2-(4'-(4-Chlorobenzyloxy)-N-isopropoxybiphenyl...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of human recombinant MMP16More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMatrix metalloproteinase-16(Human)
Instituto Superior TéCnico

Curated by ChEMBL
LigandPNGBDBM50299064(2-(Biphenyl-4-ylsulfonyl)N-hydroxybenzamide | CHEM...)
Affinity DataIC50: 5.10E+3nMAssay Description:Inhibition of human recombinant pro-MMP16 catalytic domain after 4 hrs by fluorimetryMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMatrix metalloproteinase-16(Human)
Instituto Superior TéCnico

Curated by ChEMBL
LigandPNGBDBM50299063(N-Hydroxy-2-[4-(4-methoxy-phenoxy)benzenesulfonyl]...)
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibition of human recombinant pro-MMP16 catalytic domain after 4 hrs by fluorimetryMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMatrix metalloproteinase-16(Human)
Instituto Superior TéCnico

Curated by ChEMBL
LigandPNGBDBM50299067((+/-)-2-[2-(Biphenyl-4-sulfonyl)phenyl]propionic A...)
Affinity DataIC50: 6.30E+3nMAssay Description:Inhibition of human recombinant pro-MMP16 catalytic domain after 4 hrs by fluorimetryMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMatrix metalloproteinase-16(Human)
Instituto Superior TéCnico

Curated by ChEMBL
LigandPNGBDBM50299062({2-[4-(4-Methoxy-phenoxy)benzenesulfonyl]phenyl}ac...)
Affinity DataIC50: 6.50E+3nMAssay Description:Inhibition of human recombinant pro-MMP16 catalytic domain after 4 hrs by fluorimetryMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMatrix metalloproteinase-16(Human)
Instituto Superior TéCnico

Curated by ChEMBL
LigandPNGBDBM50063917(CHEMBL279785 | marimastat | cid_119031 | (2S,3R)-N...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of MMP16 (unknown origin) catalytic domain using MCA-Arg-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-Glu-Arg-NH2 as substrate preincubated for 60 mins fol...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMatrix metalloproteinase-16(Human)
Instituto Superior TéCnico

Curated by ChEMBL
LigandPNGBDBM50294124(2-(4'-(4-Chlorobenzyloxy)-N-isopropoxybiphenyl-4-y...)
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of human recombinant MMP16More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMatrix metalloproteinase-16(Human)
Instituto Superior TéCnico

Curated by ChEMBL
LigandPNGBDBM50299057((R)-2-(N-isopropoxybiphenyl-4-ylsulfonamido)-3-met...)
Affinity DataIC50: 1.80E+4nMAssay Description:Inhibition of human recombinant pro-MMP16 catalytic domain after 4 hrs by fluorimetryMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMatrix metalloproteinase-16(Human)
Instituto Superior TéCnico

Curated by ChEMBL
LigandPNGBDBM50299068(N-Hydroxy-2-(4-methoxy-benzenesulfonyl)benzamide |...)
Affinity DataIC50: 3.10E+4nMAssay Description:Inhibition of human recombinant pro-MMP16 catalytic domain after 4 hrs by fluorimetryMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMatrix metalloproteinase-16(Human)
Instituto Superior TéCnico

Curated by ChEMBL
LigandPNGBDBM50180601(3-(4-(2-phenylethynyl)benzoyl)pentanoic acid | CHE...)
Affinity DataIC50: 3.20E+4nMAssay Description:Inhibitory activity against MMP16More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Displayed 1 to 50 (of 52 total ) | Next | Last >>
Jump to: