Compile Data Set for Download or QSAR
Report error Found 10 of ic50 data for polymerid = 50001146
TargetcGMP-dependent protein kinase 2(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM2579(CHEMBL388978 | Staurosporine, 8 | Staurosporin, 4 ...)
Affinity DataIC50: 5.80nMAssay Description:Inhibition of human PKG2 using LRRASLG as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetcGMP-dependent protein kinase 2(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50319716((3S,4R)-N-(7-chloro-1-oxo-1,2-dihydroisoquinolin-6...)
Affinity DataIC50: 24nMAssay Description:Inhibition of PRKG2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetcGMP-dependent protein kinase 2(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM2579(CHEMBL388978 | Staurosporine, 8 | Staurosporin, 4 ...)
Affinity DataIC50: 26.5nMAssay Description:Inhibition of human PKG2 using LRRASLG as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetcGMP-dependent protein kinase 2(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50630232(CHEMBL5433617)
Affinity DataIC50: 34nMAssay Description:Inhibition of PKG2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails
PubMed
TargetcGMP-dependent protein kinase 2(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50627464(CHEMBL5426285)
Affinity DataIC50: 118nMAssay Description:Inhibition of human PRKG2 assessed as remaining activity by eurofins-cerep kinase profiler analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails
PubMed
TargetcGMP-dependent protein kinase 2(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM311191(US10155760, Example 35 | (S)-1-(4-(2-(difluorometh...)
Affinity DataIC50: 380nMAssay Description:Inhibition of PKG2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetcGMP-dependent protein kinase 2(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM311193(US10155760, Example 37 | (S)-1-(2-(difluoromethyl)...)
Affinity DataIC50: 420nMAssay Description:Inhibition of PKG2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetcGMP-dependent protein kinase 2(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50519662(CHEMBL4438748)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant full-length human PRKG2 using KKLRRTLSFAEPG as substrate incubated for 40 mins in presence of [gamma33P]ATP by radiometric ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetcGMP-dependent protein kinase 2(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50631397(CHEMBL5432402)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human PRKG2 assessed as remaining activity by eurofins-cerep kinase profiler analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetcGMP-dependent protein kinase 2(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50537742(CHEMBL4634634 | US11179389, Compound 1-14)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of recombinant full length GST-tagged human PKG2 expressed in baculovirus expression system using Ser/Thr 01 as substrate after 1 hr in pr...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed