Report error Found 12 of ic50 data for polymerid = 50001062
TargetPresenilins-associated rhomboid-like protein, mitochondrial(Human)
Institute of Organic Chemistry and Biochemistry of The Czech Academy of Science
Curated by ChEMBL
Institute of Organic Chemistry and Biochemistry of The Czech Academy of Science
Curated by ChEMBL
Affinity DataIC50: 28nMAssay Description:Inhibition of recombinant C-terminal hexahistidine tagged mature human PARL using Ac-RRRAVFLA-4mc as substrate preincubated for 1 hr followed by subs...More data for this Ligand-Target Pair
TargetPresenilins-associated rhomboid-like protein, mitochondrial(Human)
Institute of Organic Chemistry and Biochemistry of The Czech Academy of Science
Curated by ChEMBL
Institute of Organic Chemistry and Biochemistry of The Czech Academy of Science
Curated by ChEMBL
Affinity DataIC50: 80nMAssay Description:Inhibition of recombinant C-terminal hexahistidine tagged mature human PARL using Ac-RRRAVFLA-4mc as substrate preincubated for 1 hr followed by subs...More data for this Ligand-Target Pair
TargetPresenilins-associated rhomboid-like protein, mitochondrial(Human)
Institute of Organic Chemistry and Biochemistry of The Czech Academy of Science
Curated by ChEMBL
Institute of Organic Chemistry and Biochemistry of The Czech Academy of Science
Curated by ChEMBL
Affinity DataIC50: 150nMAssay Description:Inhibition of human PARL expressed in human HEK293T cells cotransfected human FLAG tagged PGAM5 assessed as inhibition of CCCP induced full length PG...More data for this Ligand-Target Pair
TargetPresenilins-associated rhomboid-like protein, mitochondrial(Human)
Institute of Organic Chemistry and Biochemistry of The Czech Academy of Science
Curated by ChEMBL
Institute of Organic Chemistry and Biochemistry of The Czech Academy of Science
Curated by ChEMBL
Affinity DataIC50: 410nMAssay Description:Inhibition of tetracycline inducible FLAG tagged human PARL expressed in human PARL knockout Flp-In-T-REx-293 cells cotransfected human PGAM5-Myc ass...More data for this Ligand-Target Pair
TargetPresenilins-associated rhomboid-like protein, mitochondrial(Human)
Institute of Organic Chemistry and Biochemistry of The Czech Academy of Science
Curated by ChEMBL
Institute of Organic Chemistry and Biochemistry of The Czech Academy of Science
Curated by ChEMBL
Affinity DataIC50: 700nMAssay Description:Inhibition of human PARL transfected in HEK293T cell membrane assessed as inhibition of FP-Rh labeling treated with compound for 30 mins prior to FP-...More data for this Ligand-Target Pair
TargetPresenilins-associated rhomboid-like protein, mitochondrial(Human)
Institute of Organic Chemistry and Biochemistry of The Czech Academy of Science
Curated by ChEMBL
Institute of Organic Chemistry and Biochemistry of The Czech Academy of Science
Curated by ChEMBL
Affinity DataIC50: 900nMAssay Description:Inhibition of human PARL transfected in HEK293T cell membrane assessed as inhibition of FP-Rh labeling treated with compound for 30 mins prior to FP-...More data for this Ligand-Target Pair
TargetPresenilins-associated rhomboid-like protein, mitochondrial(Human)
Institute of Organic Chemistry and Biochemistry of The Czech Academy of Science
Curated by ChEMBL
Institute of Organic Chemistry and Biochemistry of The Czech Academy of Science
Curated by ChEMBL
Affinity DataIC50: 1.04E+3nMAssay Description:Inhibition of recombinant C-terminal hexahistidine tagged mature human PARL using Ac-RRRAVFLA-4mc as substrate preincubated for 1 hr followed by subs...More data for this Ligand-Target Pair
TargetPresenilins-associated rhomboid-like protein, mitochondrial(Human)
Institute of Organic Chemistry and Biochemistry of The Czech Academy of Science
Curated by ChEMBL
Institute of Organic Chemistry and Biochemistry of The Czech Academy of Science
Curated by ChEMBL
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of human PARL transfected in HEK293T cell membrane assessed as inhibition of FP-Rh labeling treated with compound for 30 mins prior to FP-...More data for this Ligand-Target Pair
TargetPresenilins-associated rhomboid-like protein, mitochondrial(Human)
Institute of Organic Chemistry and Biochemistry of The Czech Academy of Science
Curated by ChEMBL
Institute of Organic Chemistry and Biochemistry of The Czech Academy of Science
Curated by ChEMBL
Affinity DataIC50: 3.20E+3nMAssay Description:Inhibition of tetracycline inducible FLAG tagged human PARL expressed in human PARL knockout Flp-In-T-REx-293 cells cotransfected human PGAM5-Myc ass...More data for this Ligand-Target Pair
TargetPresenilins-associated rhomboid-like protein, mitochondrial(Human)
Institute of Organic Chemistry and Biochemistry of The Czech Academy of Science
Curated by ChEMBL
Institute of Organic Chemistry and Biochemistry of The Czech Academy of Science
Curated by ChEMBL
Affinity DataIC50: 4.30E+3nMAssay Description:Inhibition of human PARL transfected in HEK293T cell membrane assessed as inhibition of FP-Rh labeling treated with compound for 30 mins prior to FP-...More data for this Ligand-Target Pair
TargetPresenilins-associated rhomboid-like protein, mitochondrial(Human)
Institute of Organic Chemistry and Biochemistry of The Czech Academy of Science
Curated by ChEMBL
Institute of Organic Chemistry and Biochemistry of The Czech Academy of Science
Curated by ChEMBL
Affinity DataIC50: 8.80E+3nMAssay Description:Inhibition of human PARL transfected in HEK293T cell membrane assessed as inhibition of FP-Rh labeling treated with compound for 30 mins prior to FP-...More data for this Ligand-Target Pair
TargetPresenilins-associated rhomboid-like protein, mitochondrial(Human)
Institute of Organic Chemistry and Biochemistry of The Czech Academy of Science
Curated by ChEMBL
Institute of Organic Chemistry and Biochemistry of The Czech Academy of Science
Curated by ChEMBL
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of human PARL transfected in HEK293T cell membrane assessed as inhibition of FP-Rh labeling treated with compound for 30 mins prior to FP-...More data for this Ligand-Target Pair
