Compile Data Set for Download or QSAR
Report error Found 85 of ic50 data for polymerid = 50001002,50002231
TargetAdenylate cyclase type 5(Human)
Nps Allelix

Curated by ChEMBL
LigandPNGBDBM50090529(2-[1-(Naphthalene-1-sulfonyl)-1H-indol-6-yl]-octah...)
Affinity DataIC50: 7.20nMAssay Description:Antagonistic activity evaluated in adenylyl cyclase assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenylate cyclase type 5(Human)
Nps Allelix

Curated by ChEMBL
LigandPNGBDBM50128187((1R,3R)-3-(6-Amino-purin-9-yl)-cyclopentanecarboxy...)
Affinity DataIC50: 200nMAssay Description:Inhibitory activity against recombinant human adenylate cyclase 5 expressed in HEK293 cells.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenylate cyclase type 5(Human)
Nps Allelix

Curated by ChEMBL
LigandPNGBDBM50128192((1S,3R)-2-[4-(6-Amino-purin-9-yl)-cyclopent-2-enyl...)
Affinity DataIC50: 400nMAssay Description:Inhibitory activity against recombinant human adenylate cyclase 5 expressed in HEK293 cells.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenylate cyclase type 5(Human)
Nps Allelix

Curated by ChEMBL
LigandPNGBDBM50128210((1R,3R)-2-[3-(6-Amino-purin-9-yl)-cyclopentyl]-N-h...)
Affinity DataIC50: 600nMAssay Description:Inhibitory activity against recombinant human adenylate cyclase 5 expressed in HEK293 cells.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenylate cyclase type 5(Human)
Nps Allelix

Curated by ChEMBL
LigandPNGBDBM50128207((1S,3S)-2-[4-(6-Amino-purin-9-yl)-cyclopent-2-enyl...)
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibitory activity against recombinant human adenylate cyclase 5 expressed in HEK293 cells.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenylate cyclase type 5(Rat)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50140057(2-Hydroxymethyl-5-(6-methylamino-purin-9-yl)-tetra...)
Affinity DataIC50: 2.80E+3nMAssay Description:Compound was evaluated for inhibition of adenylate cyclase from rat brainMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenylate cyclase type 5(Human)
Nps Allelix

Curated by ChEMBL
LigandPNGBDBM50128209((1R,3S)-2-[4-(6-Amino-purin-9-yl)-cyclopent-2-enyl...)
Affinity DataIC50: 4.30E+3nMAssay Description:Inhibitory activity against recombinant human adenylate cyclase 5 expressed in HEK293 cells.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenylate cyclase type 5(Rat)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50370376(CHEMBL1229920)
Affinity DataIC50: 4.60E+3nMAssay Description:Compound was evaluated for inhibition of adenylate cyclase from rat brainMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenylate cyclase type 5(Human)
Nps Allelix

Curated by ChEMBL
LigandPNGBDBM50128203((1R,3S)-3-(6-Amino-purin-9-yl)-cyclopentanecarboxy...)
Affinity DataIC50: 4.60E+3nMAssay Description:Inhibitory activity against recombinant human adenylate cyclase 5 expressed in HEK293 cells.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenylate cyclase type 5(Human)
Nps Allelix

Curated by ChEMBL
LigandPNGBDBM50128199((1S,3S)-4-(6-Amino-purin-9-yl)-cyclopent-2-enecarb...)
Affinity DataIC50: 4.90E+3nMAssay Description:Inhibitory activity against recombinant human adenylate cyclase 5 expressed in HEK293 cells.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenylate cyclase type 5(Human)
Nps Allelix

Curated by ChEMBL
LigandPNGBDBM50119826(5-(6-Amino-purin-9-yl)-pentanoic acid hydroxyamide...)
Affinity DataIC50: 7.60E+3nMAssay Description:Inhibition of recombinant human adenylate cyclase 5 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenylate cyclase type 5(Human)
Nps Allelix

Curated by ChEMBL
LigandPNGBDBM50119826(5-(6-Amino-purin-9-yl)-pentanoic acid hydroxyamide...)
Affinity DataIC50: 7.60E+3nMAssay Description:Inhibitory activity against recombinant human adenylate cyclase 5 expressed in HEK293 cells.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenylate cyclase type 5(Human)
Nps Allelix

Curated by ChEMBL
LigandPNGBDBM50119826(5-(6-Amino-purin-9-yl)-pentanoic acid hydroxyamide...)
Affinity DataIC50: 7.60E+3nMAssay Description:Inhibitory concentration against type V Adenyl Cyclase enzymeMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenylate cyclase type 5(Human)
Nps Allelix

Curated by ChEMBL
LigandPNGBDBM50119832(4-(6-Amino-purin-9-yl)-N-hydroxy-butyramide | CHEM...)
Affinity DataIC50: 7.90E+3nMAssay Description:Inhibitory activity against recombinant human adenylate cyclase 5 expressed in HEK293 cells.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenylate cyclase type 5(Human)
Nps Allelix

Curated by ChEMBL
LigandPNGBDBM50119832(4-(6-Amino-purin-9-yl)-N-hydroxy-butyramide | CHEM...)
Affinity DataIC50: 7.90E+3nMAssay Description:Inhibition of recombinant human adenylate cyclase 5 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenylate cyclase type 5(Human)
Nps Allelix

Curated by ChEMBL
LigandPNGBDBM50119832(4-(6-Amino-purin-9-yl)-N-hydroxy-butyramide | CHEM...)
Affinity DataIC50: 7.90E+3nMAssay Description:Inhibitory concentration against type V Adenyl Cyclase enzymeMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenylate cyclase type 5(Human)
Nps Allelix

Curated by ChEMBL
LigandPNGBDBM50128188((1S,3R)-[4-(6-Amino-purin-9-yl)-cyclopent-2-enyl]-...)
Affinity DataIC50: 8.20E+3nMAssay Description:Inhibitory activity against recombinant human adenylate cyclase 5 expressed in HEK293 cells.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenylate cyclase type 5(Human)
Nps Allelix

Curated by ChEMBL
LigandPNGBDBM50128206((1S,3S)-2-[3-(6-Amino-purin-9-yl)-cyclopentyl]-N-h...)
Affinity DataIC50: 9.40E+3nMAssay Description:Inhibitory activity against recombinant human adenylate cyclase 5 expressed in HEK293 cells.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenylate cyclase type 5(Human)
Nps Allelix

Curated by ChEMBL
LigandPNGBDBM50128191(2-[3-(6-Amino-purin-9-yl)-cyclopentyloxy]-N-hydrox...)
Affinity DataIC50: 1.08E+4nMAssay Description:Inhibitory activity against recombinant human adenylate cyclase 5 expressed in HEK293 cells.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenylate cyclase type 5(Human)
Nps Allelix

Curated by ChEMBL
LigandPNGBDBM50119858(2-[(S)-3-((S)-6-Amino-purin-9-yl)-cyclopentyloxy]-...)
Affinity DataIC50: 1.08E+4nMAssay Description:Inhibitory concentration against Type V Adenyl Cyclase enzymeMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenylate cyclase type 5(Human)
Nps Allelix

Curated by ChEMBL
LigandPNGBDBM50119858(2-[(S)-3-((S)-6-Amino-purin-9-yl)-cyclopentyloxy]-...)
Affinity DataIC50: 1.08E+4nMAssay Description:Inhibitory concentration against type V Adenyl Cyclase enzymeMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenylate cyclase type 5(Human)
Nps Allelix

Curated by ChEMBL
LigandPNGBDBM50119855(2-{[(1S,4R)-4-(6-amino-9H-purin-9-yl)cyclopent-2-e...)
Affinity DataIC50: 1.36E+4nMAssay Description:Inhibitory concentration against Type V Adenyl Cyclase enzymeMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenylate cyclase type 5(Human)
Nps Allelix

Curated by ChEMBL
LigandPNGBDBM50128205(2-[4-(6-Amino-purin-9-yl)-cyclopent-2-enyloxy]-N-h...)
Affinity DataIC50: 1.36E+4nMAssay Description:Inhibitory activity against recombinant human adenylate cyclase 5 expressed in HEK293 cells.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenylate cyclase type 5(Human)
Nps Allelix

Curated by ChEMBL
LigandPNGBDBM50119855(2-{[(1S,4R)-4-(6-amino-9H-purin-9-yl)cyclopent-2-e...)
Affinity DataIC50: 1.36E+4nMAssay Description:Inhibitory concentration against type V Adenyl Cyclase enzymeMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenylate cyclase type 5(Rat)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50025883(2'deoxyadenosine | 2'-Deoxyadenosine | 2'-Deox...)
Affinity DataIC50: 1.50E+4nMAssay Description:Compound was evaluated for inhibition of adenylate cyclase from rat brainMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenylate cyclase type 5(Human)
Nps Allelix

Curated by ChEMBL
LigandPNGBDBM50119844(2-{[2-(6-Amino-purin-9-yl)-ethyl]-methyl-amino}-N-...)
Affinity DataIC50: 1.53E+4nMAssay Description:Inhibition of recombinant human adenylate cyclase 5 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenylate cyclase type 5(Human)
Nps Allelix

Curated by ChEMBL
LigandPNGBDBM50128204((1R,3R)-2-[4-(6-Amino-purin-9-yl)-cyclopent-2-enyl...)
Affinity DataIC50: 1.63E+4nMAssay Description:Inhibitory activity against recombinant human adenylate cyclase 5 expressed in HEK293 cells.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenylate cyclase type 5(Human)
Nps Allelix

Curated by ChEMBL
LigandPNGBDBM50128202((1R,3S)-2-[3-(6-Amino-purin-9-yl)-cyclopentyl]-N-h...)
Affinity DataIC50: 2.51E+4nMAssay Description:Inhibitory activity against recombinant human adenylate cyclase 5 expressed in HEK293 cells.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenylate cyclase type 5(Human)
Nps Allelix

Curated by ChEMBL
LigandPNGBDBM50128195((1R,3R)-[3-(6-Amino-purin-9-yl)-cyclopentyl]-aceti...)
Affinity DataIC50: 2.88E+4nMAssay Description:Inhibitory activity against recombinant human adenylate cyclase 5 expressed in HEK293 cells.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenylate cyclase type 5(Human)
Nps Allelix

Curated by ChEMBL
LigandPNGBDBM50119842(6-(6-Amino-purin-9-yl)-hexanoic acid hydroxyamide ...)
Affinity DataIC50: 3.54E+4nMAssay Description:Inhibitory activity against recombinant human adenylate cyclase 5 expressed in HEK293 cells.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenylate cyclase type 5(Human)
Nps Allelix

Curated by ChEMBL
LigandPNGBDBM50119842(6-(6-Amino-purin-9-yl)-hexanoic acid hydroxyamide ...)
Affinity DataIC50: 3.54E+4nMAssay Description:Inhibition of recombinant human adenylate cyclase 5 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenylate cyclase type 5(Human)
Nps Allelix

Curated by ChEMBL
LigandPNGBDBM50119842(6-(6-Amino-purin-9-yl)-hexanoic acid hydroxyamide ...)
Affinity DataIC50: 3.54E+4nMAssay Description:Inhibitory concentration against type V Adenyl Cyclase enzymeMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenylate cyclase type 5(Human)
Nps Allelix

Curated by ChEMBL
LigandPNGBDBM50128197((1S,3R)-2-[3-(6-Amino-purin-9-yl)-cyclopentyl]-N-h...)
Affinity DataIC50: 5.50E+4nMAssay Description:Inhibitory activity against recombinant human adenylate cyclase 5 expressed in HEK293 cells.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenylate cyclase type 5(Human)
Nps Allelix

Curated by ChEMBL
LigandPNGBDBM50128201((1S,3R)-3-(6-Amino-purin-9-yl)-cyclopentanecarboxy...)
Affinity DataIC50: 7.00E+4nMAssay Description:Inhibitory activity against recombinant human adenylate cyclase 5 expressed in HEK293 cells.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenylate cyclase type 5(Human)
Nps Allelix

Curated by ChEMBL
LigandPNGBDBM50119853(2-{[(1S,4S)-4-(6-amino-9H-purin-9-yl)cyclopent-2-e...)
Affinity DataIC50: 7.20E+4nMAssay Description:Inhibitory concentration against type V Adenyl Cyclase enzymeMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenylate cyclase type 5(Human)
Nps Allelix

Curated by ChEMBL
LigandPNGBDBM50128190((1S,3S)-[4-(6-Amino-purin-9-yl)-cyclopent-2-enyl]-...)
Affinity DataIC50: 7.32E+4nMAssay Description:Inhibitory activity against recombinant human adenylate cyclase 5 expressed in HEK293 cells.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenylate cyclase type 5(Human)
Nps Allelix

Curated by ChEMBL
LigandPNGBDBM50119860(2-{[(1S,4R)-4-(6-amino-9H-purin-9-yl)cyclopent-2-e...)
Affinity DataIC50: 7.80E+4nMAssay Description:Inhibitory concentration against type V Adenyl Cyclase enzymeMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenylate cyclase type 5(Human)
Nps Allelix

Curated by ChEMBL
LigandPNGBDBM50128186((1S,3S)-3-(6-Amino-purin-9-yl)-cyclopentanecarboxy...)
Affinity DataIC50: 7.80E+4nMAssay Description:Inhibitory activity against recombinant human adenylate cyclase 5 expressed in HEK293 cells.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenylate cyclase type 5(Human)
Nps Allelix

Curated by ChEMBL
LigandPNGBDBM50119857([(S)-3-((S)-6-Amino-purin-9-yl)-cyclopentyloxy]-ac...)
Affinity DataIC50: 7.90E+4nMAssay Description:Inhibitory concentration against type V Adenyl Cyclase enzymeMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenylate cyclase type 5(Human)
Nps Allelix

Curated by ChEMBL
LigandPNGBDBM50119821(2-[3-(6-Amino-purin-9-yl)-propoxy]-N-hydroxy-aceta...)
Affinity DataIC50: 9.40E+4nMAssay Description:Inhibition of recombinant human adenylate cyclase 5 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenylate cyclase type 5(Human)
Nps Allelix

Curated by ChEMBL
LigandPNGBDBM50119821(2-[3-(6-Amino-purin-9-yl)-propoxy]-N-hydroxy-aceta...)
Affinity DataIC50: 9.40E+4nMAssay Description:Inhibitory concentration against type V Adenyl Cyclase enzymeMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenylate cyclase type 5(Human)
Nps Allelix

Curated by ChEMBL
LigandPNGBDBM50119854(2-{[(1R,4S)-4-(6-amino-9H-purin-9-yl)cyclopent-2-e...)
Affinity DataIC50: 9.60E+4nMAssay Description:Inhibitory concentration against Type V Adenyl Cyclase enzymeMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenylate cyclase type 5(Human)
Nps Allelix

Curated by ChEMBL
LigandPNGBDBM50119861(2-{[(1R,4S)-4-(6-amino-9H-purin-9-yl)cyclopent-2-e...)
Affinity DataIC50: 9.80E+4nMAssay Description:Inhibitory concentration against type V Adenyl Cyclase enzymeMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenylate cyclase type 5(Rat)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50008363(CHEMBL279654 | 5-(6-Amino-2-fluoro-purin-9-yl)-2-h...)
Affinity DataIC50: 1.00E+5nMAssay Description:Compound was evaluated for inhibition of adenylate cyclase from rat brainMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenylate cyclase type 5(Human)
Nps Allelix

Curated by ChEMBL
LigandPNGBDBM50128194((1R,3R)-4-(6-Amino-purin-9-yl)-cyclopent-2-enecarb...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibitory activity against recombinant human adenylate cyclase 5 expressed in HEK293 cells.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenylate cyclase type 5(Human)
Nps Allelix

Curated by ChEMBL
LigandPNGBDBM50128189((1S,3S)-[3-(6-Amino-purin-9-yl)-cyclopentyl]-aceti...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibitory activity against recombinant human adenylate cyclase 5 expressed in HEK293 cells.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenylate cyclase type 5(Human)
Nps Allelix

Curated by ChEMBL
LigandPNGBDBM50119854(2-{[(1R,4S)-4-(6-amino-9H-purin-9-yl)cyclopent-2-e...)
Affinity DataIC50: 1.02E+5nMAssay Description:Inhibitory concentration against type V Adenyl Cyclase enzymeMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenylate cyclase type 5(Human)
Nps Allelix

Curated by ChEMBL
LigandPNGBDBM50119851(2-[(R)-3-((R)-6-Amino-purin-9-yl)-cyclopentyloxy]-...)
Affinity DataIC50: 1.10E+5nMAssay Description:Inhibitory concentration against type V Adenyl Cyclase enzymeMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenylate cyclase type 5(Human)
Nps Allelix

Curated by ChEMBL
LigandPNGBDBM50119829([3-(6-Amino-purin-9-yl)-propoxy]-acetic acid | CHE...)
Affinity DataIC50: 1.41E+5nMAssay Description:Inhibition of recombinant human adenylate cyclase 5 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenylate cyclase type 5(Human)
Nps Allelix

Curated by ChEMBL
LigandPNGBDBM50128211((1S,3R)-4-(6-Amino-purin-9-yl)-cyclopent-2-enecarb...)
Affinity DataIC50: 1.88E+5nMAssay Description:Inhibitory activity against recombinant human adenylate cyclase 5 expressed in HEK293 cells.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
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