Compile Data Set for Download or QSAR
Report error Found 210 of ic50 data for polymerid = 50000950
TargetRNA demethylase ALKBH5(Human)
Nankai University

Curated by ChEMBL
LigandPNGBDBM50592094(CHEMBL5203605)
Affinity DataIC50: 21nMAssay Description:Inhibition of human recombinant ALKBH5 (66 to 292 residues) expressed in Escherichia coli BL21 (DE3) cells using FAM-labeled ssRNA (5'-CUCGAUACG(m^6A...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetRNA demethylase ALKBH5(Human)
Nankai University

Curated by ChEMBL
LigandPNGBDBM50592105(CHEMBL5172537)
Affinity DataIC50: 61nMAssay Description:Inhibition of human recombinant ALKBH5 (66 to 292 residues) expressed in Escherichia coli BL21 (DE3) cells using FAM-labeled ssRNA (5'-CUCGAUACG(m^6A...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetRNA demethylase ALKBH5(Human)
Nankai University

Curated by ChEMBL
LigandPNGBDBM624931(US20230322715, Compound TR-ALKBH5-29)
Affinity DataIC50: 110nMAssay Description:The in vitro inhibition assay method was adapted from Svenson and Jaffrey, 2016. All reactions were performed in a 96-well plate with 200 μL ass...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetRNA demethylase ALKBH5(Human)
Nankai University

Curated by ChEMBL
LigandPNGBDBM624926(US20230322715, Compound TR-ALKBH5-04)
Affinity DataIC50: 240nMAssay Description:The in vitro inhibition assay method was adapted from Svenson and Jaffrey, 2016. All reactions were performed in a 96-well plate with 200 μL ass...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetRNA demethylase ALKBH5(Human)
Nankai University

Curated by ChEMBL
LigandPNGBDBM624942(US20230322715, Compound TR-ALKBH5-42)
Affinity DataIC50: 250nMAssay Description:The in vitro inhibition assay method was adapted from Svenson and Jaffrey, 2016. All reactions were performed in a 96-well plate with 200 μL ass...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetRNA demethylase ALKBH5(Human)
Nankai University

Curated by ChEMBL
LigandPNGBDBM50592118(CHEMBL5205465)
Affinity DataIC50: 396nMAssay Description:Inhibition of human recombinant ALKBH5 (66 to 292 residues) expressed in Escherichia coli BL21 (DE3) cells using FAM-labeled ssRNA (5'-CUCGAUACG(m^6A...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetRNA demethylase ALKBH5(Human)
Nankai University

Curated by ChEMBL
LigandPNGBDBM624937(US20230322715, Compound TR-ALKBH5-36)
Affinity DataIC50: 400nMAssay Description:The in vitro inhibition assay method was adapted from Svenson and Jaffrey, 2016. All reactions were performed in a 96-well plate with 200 μL ass...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetRNA demethylase ALKBH5(Human)
Nankai University

Curated by ChEMBL
LigandPNGBDBM50592104(CHEMBL5175898)
Affinity DataIC50: 421nMAssay Description:Inhibition of human recombinant ALKBH5 (66 to 292 residues) expressed in Escherichia coli BL21 (DE3) cells using FAM-labeled ssRNA (5'-CUCGAUACG(m^6A...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetRNA demethylase ALKBH5(Human)
Nankai University

Curated by ChEMBL
LigandPNGBDBM624941(US20230322715, Compound TR-ALKBH5-41)
Affinity DataIC50: 450nMAssay Description:The in vitro inhibition assay method was adapted from Svenson and Jaffrey, 2016. All reactions were performed in a 96-well plate with 200 μL ass...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetRNA demethylase ALKBH5(Human)
Nankai University

Curated by ChEMBL
LigandPNGBDBM624928(US20230322715, Compound TR-ALKBH5-08)
Affinity DataIC50: 500nMAssay Description:The in vitro inhibition assay method was adapted from Svenson and Jaffrey, 2016. All reactions were performed in a 96-well plate with 200 μL ass...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetRNA demethylase ALKBH5(Human)
Nankai University

Curated by ChEMBL
LigandPNGBDBM50592117(CHEMBL5186162)
Affinity DataIC50: 559nMAssay Description:Inhibition of human recombinant ALKBH5 (66 to 292 residues) expressed in Escherichia coli BL21 (DE3) cells using FAM-labeled ssRNA (5'-CUCGAUACG(m^6A...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetRNA demethylase ALKBH5(Human)
Nankai University

Curated by ChEMBL
LigandPNGBDBM50592096(CHEMBL5208142)
Affinity DataIC50: 591nMAssay Description:Inhibition of human recombinant ALKBH5 (66 to 292 residues) expressed in Escherichia coli BL21 (DE3) cells using FAM-labeled ssRNA (5'-CUCGAUACG(m^6A...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetRNA demethylase ALKBH5(Human)
Nankai University

Curated by ChEMBL
LigandPNGBDBM50592100(CHEMBL5180828)
Affinity DataIC50: 727nMAssay Description:Inhibition of human recombinant ALKBH5 (66 to 292 residues) expressed in Escherichia coli BL21 (DE3) cells using FAM-labeled ssRNA (5'-CUCGAUACG(m^6A...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetRNA demethylase ALKBH5(Human)
Nankai University

Curated by ChEMBL
LigandPNGBDBM50557836(CHEMBL4752151)
Affinity DataIC50: 840nMAssay Description:Inhibition of ALKBH5 demethylase activity (unknown origin) assessed as increase in methylated 6A-RNA level incubated for 2 hrs by colorimetric analys...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetRNA demethylase ALKBH5(Human)
Nankai University

Curated by ChEMBL
LigandPNGBDBM50557836(CHEMBL4752151)
Affinity DataIC50: 840nMAssay Description:Inhibition of recombinant ALKBH5 (unknown origin) mediated demethylase activity using methylated N6-adenine RNA probe with CUUGUCAm6ACAGCAGA sequence...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetRNA demethylase ALKBH5(Human)
Nankai University

Curated by ChEMBL
LigandPNGBDBM50599016(CHEMBL5198269 | US20230322715, Compound TR-FTO-16)
Affinity DataIC50: 870nMAssay Description:The in vitro inhibition assay method was adapted from Svenson and Jaffrey, 2016. All reactions were performed in a 96-well plate with 200 μL ass...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetRNA demethylase ALKBH5(Human)
Nankai University

Curated by ChEMBL
LigandPNGBDBM50592116(CHEMBL5202184)
Affinity DataIC50: 890nMAssay Description:Inhibition of human recombinant ALKBH5 (66 to 292 residues) expressed in Escherichia coli BL21 (DE3) cells using FAM-labeled ssRNA (5'-CUCGAUACG(m^6A...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetRNA demethylase ALKBH5(Human)
Nankai University

Curated by ChEMBL
LigandPNGBDBM624905(US20230322715, Compound ALK-04)
Affinity DataIC50: 900nMAssay Description:The in vitro inhibition assay method was adapted from Svenson and Jaffrey, 2016. All reactions were performed in a 96-well plate with 200 μL ass...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetRNA demethylase ALKBH5(Human)
Nankai University

Curated by ChEMBL
LigandPNGBDBM624919(US20230322715, Compound ALK-25)
Affinity DataIC50: 900nMAssay Description:The in vitro inhibition assay method was adapted from Svenson and Jaffrey, 2016. All reactions were performed in a 96-well plate with 200 μL ass...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetRNA demethylase ALKBH5(Human)
Nankai University

Curated by ChEMBL
LigandPNGBDBM50599024(CHEMBL5188113)
Affinity DataIC50: 920nMAssay Description:Inhibition of ALKBH5 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetRNA demethylase ALKBH5(Human)
Nankai University

Curated by ChEMBL
LigandPNGBDBM624874(US20230322715, Compound TR-FTO-39)
Affinity DataIC50: 920nMAssay Description:The in vitro inhibition assay method was adapted from Svenson and Jaffrey, 2016. All reactions were performed in a 96-well plate with 200 μL ass...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetRNA demethylase ALKBH5(Human)
Nankai University

Curated by ChEMBL
LigandPNGBDBM624932(US20230322715, Compound TR-ALKBH5-30)
Affinity DataIC50: 1.00E+3nMAssay Description:The in vitro inhibition assay method was adapted from Svenson and Jaffrey, 2016. All reactions were performed in a 96-well plate with 200 μL ass...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetRNA demethylase ALKBH5(Human)
Nankai University

Curated by ChEMBL
LigandPNGBDBM50416557(CHEMBL5282066)
Affinity DataIC50: 1.24E+3nMAssay Description:Inhibition of ALKBH5 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetRNA demethylase ALKBH5(Human)
Nankai University

Curated by ChEMBL
LigandPNGBDBM624920(US20230322715, Compound ALK-30)
Affinity DataIC50: 1.40E+3nMAssay Description:The in vitro inhibition assay method was adapted from Svenson and Jaffrey, 2016. All reactions were performed in a 96-well plate with 200 μL ass...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetRNA demethylase ALKBH5(Human)
Nankai University

Curated by ChEMBL
LigandPNGBDBM624929(US20230322715, Compound TR-ALKBH5-25)
Affinity DataIC50: 1.60E+3nMAssay Description:The in vitro inhibition assay method was adapted from Svenson and Jaffrey, 2016. All reactions were performed in a 96-well plate with 200 μL ass...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetRNA demethylase ALKBH5(Human)
Nankai University

Curated by ChEMBL
LigandPNGBDBM50357221(CHEMBL442218 | US20230322715, Compound ALK-10)
Affinity DataIC50: 1.70E+3nMAssay Description:The in vitro inhibition assay method was adapted from Svenson and Jaffrey, 2016. All reactions were performed in a 96-well plate with 200 μL ass...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetRNA demethylase ALKBH5(Human)
Nankai University

Curated by ChEMBL
LigandPNGBDBM50557837(CHEMBL4753950)
Affinity DataIC50: 1.79E+3nMAssay Description:Inhibition of ALKBH5 demethylase activity (unknown origin) assessed as increase in methylated 6A-RNA level incubated for 2 hrs by colorimetric analys...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetRNA demethylase ALKBH5(Human)
Nankai University

Curated by ChEMBL
LigandPNGBDBM50557837(CHEMBL4753950)
Affinity DataIC50: 1.79E+3nMAssay Description:Inhibition of recombinant ALKBH5 (unknown origin) mediated demethylase activity using methylated N6-adenine RNA probe with CUUGUCAm6ACAGCAGA sequence...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetRNA demethylase ALKBH5(Human)
Nankai University

Curated by ChEMBL
LigandPNGBDBM50592071(CHEMBL5169684)
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of human full length N-terminal His6-tagged ALKBH5 (66 to 292 residues) expressed in Escherichia coli BL21 (DE3) Rosetta cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetRNA demethylase ALKBH5(Human)
Nankai University

Curated by ChEMBL
LigandPNGBDBM50592071(CHEMBL5169684)
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of N-terminal truncated human ALKBH5 (66 to 292 residues) expressed in Escherichia coli BL21 (DE3) Rosetta cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetRNA demethylase ALKBH5(Human)
Nankai University

Curated by ChEMBL
LigandPNGBDBM624927(US20230322715, Compound TR-ALKBH5-05)
Affinity DataIC50: 1.90E+3nMAssay Description:The in vitro inhibition assay method was adapted from Svenson and Jaffrey, 2016. All reactions were performed in a 96-well plate with 200 μL ass...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetRNA demethylase ALKBH5(Human)
Nankai University

Curated by ChEMBL
LigandPNGBDBM624938(US20230322715, Compound TR-ALKBH5-38)
Affinity DataIC50: 1.90E+3nMAssay Description:The in vitro inhibition assay method was adapted from Svenson and Jaffrey, 2016. All reactions were performed in a 96-well plate with 200 μL ass...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetRNA demethylase ALKBH5(Human)
Nankai University

Curated by ChEMBL
LigandPNGBDBM50485565(CHEMBL465179)
Affinity DataIC50: 1.98E+3nMAssay Description:Inhibition of ALKBH5 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetRNA demethylase ALKBH5(Human)
Nankai University

Curated by ChEMBL
LigandPNGBDBM624930(US20230322715, Compound TR-ALKBH5-27)
Affinity DataIC50: 2.00E+3nMAssay Description:The in vitro inhibition assay method was adapted from Svenson and Jaffrey, 2016. All reactions were performed in a 96-well plate with 200 μL ass...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetRNA demethylase ALKBH5(Human)
Nankai University

Curated by ChEMBL
LigandPNGBDBM624934(US20230322715, Compound TR-ALKBH5-32)
Affinity DataIC50: 2.20E+3nMAssay Description:The in vitro inhibition assay method was adapted from Svenson and Jaffrey, 2016. All reactions were performed in a 96-well plate with 200 μL ass...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetRNA demethylase ALKBH5(Human)
Nankai University

Curated by ChEMBL
LigandPNGBDBM50599013(CHEMBL5199622 | US20230322715, Compound TR-FTO-44)
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of ALKBH5 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetRNA demethylase ALKBH5(Human)
Nankai University

Curated by ChEMBL
LigandPNGBDBM50599013(CHEMBL5199622 | US20230322715, Compound TR-FTO-44)
Affinity DataIC50: 2.30E+3nMAssay Description:The in vitro inhibition assay method was adapted from Svenson and Jaffrey, 2016. All reactions were performed in a 96-well plate with 200 μL ass...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetRNA demethylase ALKBH5(Human)
Nankai University

Curated by ChEMBL
LigandPNGBDBM624940(US20230322715, Compound TR-ALKBH5-40)
Affinity DataIC50: 2.30E+3nMAssay Description:The in vitro inhibition assay method was adapted from Svenson and Jaffrey, 2016. All reactions were performed in a 96-well plate with 200 μL ass...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetRNA demethylase ALKBH5(Human)
Nankai University

Curated by ChEMBL
LigandPNGBDBM50599017(CHEMBL5195274 | US20230322715, Compound TR-FTO-17)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of ALKBH5 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetRNA demethylase ALKBH5(Human)
Nankai University

Curated by ChEMBL
LigandPNGBDBM50599017(CHEMBL5195274 | US20230322715, Compound TR-FTO-17)
Affinity DataIC50: 2.50E+3nMAssay Description:The in vitro inhibition assay method was adapted from Svenson and Jaffrey, 2016. All reactions were performed in a 96-well plate with 200 μL ass...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetRNA demethylase ALKBH5(Human)
Nankai University

Curated by ChEMBL
LigandPNGBDBM50599033(CHEMBL5208226)
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibition of ALKBH5 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetRNA demethylase ALKBH5(Human)
Nankai University

Curated by ChEMBL
LigandPNGBDBM624880(US20230322715, Compound TR-FTO-48)
Affinity DataIC50: 2.60E+3nMAssay Description:The in vitro inhibition assay method was adapted from Svenson and Jaffrey, 2016. All reactions were performed in a 96-well plate with 200 μL ass...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetRNA demethylase ALKBH5(Human)
Nankai University

Curated by ChEMBL
LigandPNGBDBM624935(US20230322715, Compound TR-ALKBH5-33)
Affinity DataIC50: 2.60E+3nMAssay Description:The in vitro inhibition assay method was adapted from Svenson and Jaffrey, 2016. All reactions were performed in a 96-well plate with 200 μL ass...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetRNA demethylase ALKBH5(Human)
Nankai University

Curated by ChEMBL
LigandPNGBDBM50592109(CHEMBL5195733)
Affinity DataIC50: 2.73E+3nMAssay Description:Inhibition of human recombinant ALKBH5 (66 to 292 residues) expressed in Escherichia coli BL21 (DE3) cells using FAM-labeled ssRNA (5'-CUCGAUACG(m^6A...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetRNA demethylase ALKBH5(Human)
Nankai University

Curated by ChEMBL
LigandPNGBDBM624918(US20230322715, Compound ALK-23)
Affinity DataIC50: 2.80E+3nMAssay Description:The in vitro inhibition assay method was adapted from Svenson and Jaffrey, 2016. All reactions were performed in a 96-well plate with 200 μL ass...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetRNA demethylase ALKBH5(Human)
Nankai University

Curated by ChEMBL
LigandPNGBDBM50396018(CHEMBL1230640)
Affinity DataIC50: 2.90E+3nMAssay Description:Inhibition of human ALKBH5 (74 to 294 residues) expressed in Escherichia coli BL21(DE3) V2R-pRARE cells using biotin labeled m6A-ss-RNA with UACACUCG...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetRNA demethylase ALKBH5(Human)
Nankai University

Curated by ChEMBL
LigandPNGBDBM50631032(CHEMBL5401284)
Affinity DataIC50: 2.97E+3nMAssay Description:Inhibition of ALKBH5 (66 to 292 residues)(unknown origin) expressed in Escherichia coli BL21(DE3) using 5'-ATTGTCA(m6A)CAGCAGA-FAM-3' as substrate in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetRNA demethylase ALKBH5(Human)
Nankai University

Curated by ChEMBL
LigandPNGBDBM50599025(CHEMBL5207866 | US20230322715, Compound TR-FTO-40)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of ALKBH5 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetRNA demethylase ALKBH5(Human)
Nankai University

Curated by ChEMBL
LigandPNGBDBM50599025(CHEMBL5207866 | US20230322715, Compound TR-FTO-40)
Affinity DataIC50: 3.00E+3nMAssay Description:The in vitro inhibition assay method was adapted from Svenson and Jaffrey, 2016. All reactions were performed in a 96-well plate with 200 μL ass...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetRNA demethylase ALKBH5(Human)
Nankai University

Curated by ChEMBL
LigandPNGBDBM624939(US20230322715, Compound TR-ALKBH5-39)
Affinity DataIC50: 3.10E+3nMAssay Description:The in vitro inhibition assay method was adapted from Svenson and Jaffrey, 2016. All reactions were performed in a 96-well plate with 200 μL ass...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

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