Compile Data Set for Download or QSAR
Report error Found 123 of ic50 data for polymerid = 50000581,50004328
TargetCatenin beta-1(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM50408050(CHEMBL5282944)
Affinity DataIC50: 4.20nMAssay Description:Binding affinity to human beta catenin assessed as dissociation constantMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetCatenin beta-1(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM396286(US10314832, Compound 2)
Affinity DataIC50: 13nMAssay Description:Compounds that enhance the Wnt activity, or Activators, were assayed as follows. Reporter cell lines were generated by stably transducing cells of ca...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetCatenin beta-1(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM396284(US10314832, Compound 1)
Affinity DataIC50: 28.5nMAssay Description:Compounds that enhance the Wnt activity, or Activators, were assayed as follows. Reporter cell lines were generated by stably transducing cells of ca...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetCatenin beta-1(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM396287(US10314832, Compound 3)
Affinity DataIC50: 38.5nMAssay Description:Compounds that enhance the Wnt activity, or Activators, were assayed as follows. Reporter cell lines were generated by stably transducing cells of ca...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetCatenin beta-1(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM396292(US10314832, Compound 8)
Affinity DataIC50: 83nMAssay Description:Compounds that enhance the Wnt activity, or Activators, were assayed as follows. Reporter cell lines were generated by stably transducing cells of ca...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetCatenin beta-1(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM396291(US10314832, Compound 7)
Affinity DataIC50: 183nMAssay Description:Compounds that enhance the Wnt activity, or Activators, were assayed as follows. Reporter cell lines were generated by stably transducing cells of ca...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetCatenin beta-1(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM50014132(CHEMBL2323032)
Affinity DataIC50: 500nMAssay Description:Inhibition of beta catenin (unknown origin)More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetCatenin beta-1(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM396288(US10314832, Compound 11 | US10314832, Compound 4)
Affinity DataIC50: 805nMAssay Description:Compounds that enhance the Wnt activity, or Activators, were assayed as follows. Reporter cell lines were generated by stably transducing cells of ca...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetCatenin beta-1(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM396289(US10314832, Compound 5)
Affinity DataIC50: 1.27E+3nMAssay Description:Compounds that enhance the Wnt activity, or Activators, were assayed as follows. Reporter cell lines were generated by stably transducing cells of ca...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetCatenin beta-1(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM50616640(CHEMBL5398967)
Affinity DataIC50: 1.37E+3nMAssay Description:Inhibition of beta-catenin transcriptional activity in human HCT-116 cells harbouring TCF/LEF luciferase reporter gene assessed as TCF/LEF reporter a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetCatenin beta-1(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM396298(US10314832, Compound 15)
Affinity DataIC50: 1.39E+3nMAssay Description:Compounds that enhance the Wnt activity, or Activators, were assayed as follows. Reporter cell lines were generated by stably transducing cells of ca...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetCatenin beta-1(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM50616633(CHEMBL5416539)
Affinity DataIC50: 1.56E+3nMAssay Description:Inhibition of beta-catenin transcriptional activity in human HCT-116 cells harbouring TCF/LEF luciferase reporter gene assessed as TCF/LEF reporter a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetCatenin beta-1(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM50509812(CHEMBL4548532)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of C-terminal fluorescein-labeled human TCF4 (7 to 51 residues) binding to wild-type C-terminal His6-tagged beta-catenin (138 to 781 resid...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetCatenin beta-1(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM50589223(CHEMBL5185515)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of human recombinant GST tagged beta catenin ARD by Alphascreen assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetCatenin beta-1(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM50616639(CHEMBL5399058)
Affinity DataIC50: 2.06E+3nMAssay Description:Inhibition of beta-catenin transcriptional activity in human HCT-116 cells harbouring TCF/LEF luciferase reporter gene assessed as TCF/LEF reporter a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetCatenin beta-1(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM396290(US10314832, Compound 6)
Affinity DataIC50: 2.10E+3nMAssay Description:Compounds that enhance the Wnt activity, or Activators, were assayed as follows. Reporter cell lines were generated by stably transducing cells of ca...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetCatenin beta-1(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM50509813(CHEMBL4451478)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of C-terminal fluorescein-labeled human TCF4 (7 to 51 residues) binding to wild-type C-terminal His6-tagged beta-catenin (138 to 781 resid...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetCatenin beta-1(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM396299(US10314832, Compound 16)
Affinity DataIC50: 2.57E+3nMAssay Description:Compounds that enhance the Wnt activity, or Activators, were assayed as follows. Reporter cell lines were generated by stably transducing cells of ca...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetCatenin beta-1(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM396302(US10314832, Compound 19)
Affinity DataIC50: 3.90E+3nMAssay Description:Compounds that enhance the Wnt activity, or Activators, were assayed as follows. Reporter cell lines were generated by stably transducing cells of ca...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetCatenin beta-1(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM50436054(CHEMBL2397077)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of beta-catenin-mediated transcriptional activity in Wnt3a-stimulated human HeLa cells after 24 hrs by Dual-Glo luciferase reporter gene a...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCatenin beta-1(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM50436055(CHEMBL2397076)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of beta-catenin-mediated transcriptional activity in Wnt3a-stimulated human HeLa cells after 24 hrs by Dual-Glo luciferase reporter gene a...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCatenin beta-1(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM50509810(CHEMBL4464142)
Affinity DataIC50: 5.90E+3nMAssay Description:Inhibition of C-terminal fluorescein-labeled human TCF4 (7 to 51 residues) binding to wild-type C-terminal His6-tagged beta-catenin (138 to 781 resid...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetCatenin beta-1(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM396301(US10314832, Compound 18)
Affinity DataIC50: 6.00E+3nMAssay Description:Compounds that enhance the Wnt activity, or Activators, were assayed as follows. Reporter cell lines were generated by stably transducing cells of ca...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetCatenin beta-1(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM50014148(CHEMBL3260853)
Affinity DataIC50: 6.30E+3nMAssay Description:Inhibition of human wild-type beta-catenin (residues 138-686)/C-terminally fluorescein labeled human wild-type Tcf4 (residues 7-51) interaction after...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCatenin beta-1(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM50509801(CHEMBL4464433)
Affinity DataIC50: 7.30E+3nMAssay Description:Inhibition of C-terminal fluorescein-labeled human TCF4 (7 to 51 residues) binding to wild-type C-terminal His6-tagged beta-catenin (138 to 781 resid...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetCatenin beta-1(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM50509781(CHEMBL4450852)
Affinity DataIC50: 7.50E+3nMAssay Description:Inhibition of C-terminal fluorescein-labeled human TCF4 (7 to 51 residues) binding to wild-type C-terminal His6-tagged beta-catenin (138 to 781 resid...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCatenin beta-1(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM50509803(CHEMBL4449577)
Affinity DataIC50: 8.50E+3nMAssay Description:Inhibition of C-terminal fluorescein-labeled human TCF4 (7 to 51 residues) binding to wild-type C-terminal His6-tagged beta-catenin (138 to 781 resid...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetCatenin beta-1(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM50509802(CHEMBL4515157)
Affinity DataIC50: 8.90E+3nMAssay Description:Inhibition of C-terminal fluorescein-labeled human TCF4 (7 to 51 residues) binding to wild-type C-terminal His6-tagged beta-catenin (138 to 781 resid...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetCatenin beta-1(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM50509818(CHEMBL4579221)
Affinity DataIC50: 9.30E+3nMAssay Description:Inhibition of C-terminal fluorescein-labeled human TCF4 (7 to 51 residues) binding to wild-type C-terminal His6-tagged beta-catenin (138 to 781 resid...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetCatenin beta-1(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM50509819(CHEMBL4460073)
Affinity DataIC50: 9.80E+3nMAssay Description:Inhibition of C-terminal fluorescein-labeled human TCF4 (7 to 51 residues) binding to wild-type C-terminal His6-tagged beta-catenin (138 to 781 resid...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetCatenin beta-1(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM396293(US10314832, Compound 9)
Affinity DataIC50: 1.00E+4nMAssay Description:Compounds that enhance the Wnt activity, or Activators, were assayed as follows. Reporter cell lines were generated by stably transducing cells of ca...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetCatenin beta-1(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM396294(US10314832, Compound 10)
Affinity DataIC50: 1.00E+4nMAssay Description:Compounds that enhance the Wnt activity, or Activators, were assayed as follows. Reporter cell lines were generated by stably transducing cells of ca...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetCatenin beta-1(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM396288(US10314832, Compound 11 | US10314832, Compound 4)
Affinity DataIC50: 1.00E+4nMAssay Description:Compounds that enhance the Wnt activity, or Activators, were assayed as follows. Reporter cell lines were generated by stably transducing cells of ca...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetCatenin beta-1(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM396296(US10314832, Compound 12)
Affinity DataIC50: 1.00E+4nMAssay Description:Compounds that enhance the Wnt activity, or Activators, were assayed as follows. Reporter cell lines were generated by stably transducing cells of ca...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetCatenin beta-1(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM396297(US10314832, Compound 14)
Affinity DataIC50: 1.00E+4nMAssay Description:Compounds that enhance the Wnt activity, or Activators, were assayed as follows. Reporter cell lines were generated by stably transducing cells of ca...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetCatenin beta-1(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM396300(US10314832, Compound 17)
Affinity DataIC50: 1.00E+4nMAssay Description:Compounds that enhance the Wnt activity, or Activators, were assayed as follows. Reporter cell lines were generated by stably transducing cells of ca...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetCatenin beta-1(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM50509804(CHEMBL4455488)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of C-terminal fluorescein-labeled human TCF4 (7 to 51 residues) binding to wild-type C-terminal His6-tagged beta-catenin (138 to 781 resid...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetCatenin beta-1(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM50509817(CHEMBL4565782)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of C-terminal fluorescein-labeled human TCF4 (7 to 51 residues) binding to wild-type C-terminal His6-tagged beta-catenin (138 to 781 resid...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetCatenin beta-1(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM50509799(CHEMBL4532791)
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of C-terminal fluorescein-labeled human TCF4 (7 to 51 residues) binding to wild-type C-terminal His6-tagged beta-catenin (138 to 781 resid...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetCatenin beta-1(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM50509807(CHEMBL4560197)
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of C-terminal fluorescein-labeled human TCF4 (7 to 51 residues) binding to wild-type C-terminal His6-tagged beta-catenin (138 to 781 resid...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetCatenin beta-1(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM50577925(CHEMBL4846565)
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of beta-catenin (unknown origin) transfected in HEK293 cells cotransfected with pCMV-RL assessed as reduction in luciferase activity measu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetCatenin beta-1(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM50509829(CHEMBL4456139)
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of C-terminal fluorescein-labeled human TCF4 (7 to 51 residues) binding to wild-type C-terminal His6-tagged beta-catenin (138 to 781 resid...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetCatenin beta-1(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM50014132(CHEMBL2323032)
Affinity DataIC50: 1.30E+4nMAssay Description:Inhibition of human wild-type beta-catenin (residues 138-686)/C-terminally fluorescein labeled human wild-type Tcf4 (residues 7-51) interaction after...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCatenin beta-1(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM50509780(CHEMBL4538548)
Affinity DataIC50: 1.30E+4nMAssay Description:Inhibition of C-terminal fluorescein-labeled human TCF4 (7 to 51 residues) binding to wild-type C-terminal His6-tagged beta-catenin (138 to 781 resid...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetCatenin beta-1(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM50509796(CHEMBL4535419)
Affinity DataIC50: 1.30E+4nMAssay Description:Inhibition of C-terminal fluorescein-labeled human TCF4 (7 to 51 residues) binding to wild-type C-terminal His6-tagged beta-catenin (138 to 781 resid...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetCatenin beta-1(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM50509833(CHEMBL4464915)
Affinity DataIC50: 1.30E+4nMAssay Description:Inhibition of C-terminal fluorescein-labeled human TCF4 (7 to 51 residues) binding to wild-type C-terminal His6-tagged beta-catenin (138 to 781 resid...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetCatenin beta-1(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM50509798(CHEMBL4515538)
Affinity DataIC50: 1.40E+4nMAssay Description:Inhibition of C-terminal fluorescein-labeled human TCF4 (7 to 51 residues) binding to wild-type C-terminal His6-tagged beta-catenin (138 to 781 resid...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetCatenin beta-1(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM50509805(CHEMBL4451874)
Affinity DataIC50: 1.40E+4nMAssay Description:Inhibition of C-terminal fluorescein-labeled human TCF4 (7 to 51 residues) binding to wild-type C-terminal His6-tagged beta-catenin (138 to 781 resid...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetCatenin beta-1(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM50094490(CHEMBL3589156)
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of human wild-type beta-catenin (residues 138-686)/C-terminally fluorescein labeled human wild-type Tcf4 (residues 7-51) interaction after...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCatenin beta-1(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM50014148(CHEMBL3260853)
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of C-terminal fluorescein-labeled human TCF4 (7 to 51 residues) binding to wild-type C-terminal His6-tagged beta-catenin (138 to 781 resid...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
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