Compile Data Set for Download or QSAR
Report error Found 136 of ic50 data for polymerid = 50000514,50002538,50004371
TargetDeoxyhypusine synthase(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50612294(CHEMBL5281395)
Affinity DataIC50: 9.20nMAssay Description:Displacement of [3H]spermidine trihydrochloride from N-terminal 6his tagged TEV fused human DHPS expressed in Escherichia coli BL21 (DE3) incubated f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetDeoxyhypusine synthase(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50612293(CHEMBL5265996)
Affinity DataIC50: 11nMAssay Description:Displacement of [3H]spermidine trihydrochloride from N-terminal 6his tagged TEV fused human DHPS expressed in Escherichia coli BL21 (DE3) incubated f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetDeoxyhypusine synthase(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50612290(CHEMBL5288132)
Affinity DataIC50: 12nMAssay Description:Displacement of [3H]spermidine trihydrochloride from N-terminal 6his tagged TEV fused human DHPS expressed in Escherichia coli BL21 (DE3) incubated f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetDeoxyhypusine synthase(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50583904(CHEMBL5091313)
Affinity DataIC50: 14nMAssay Description:Inhibition of DHPS (unknown origin ) incubated for 30 mins by NAD/NADH-Glow assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDeoxyhypusine synthase(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50612285(CHEMBL5269564)
Affinity DataIC50: 14nMAssay Description:Displacement of [3H]spermidine trihydrochloride from N-terminal 6his tagged TEV fused human DHPS expressed in Escherichia coli BL21 (DE3) incubated f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetDeoxyhypusine synthase(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50612287(CHEMBL5274333)
Affinity DataIC50: 18nMAssay Description:Displacement of [3H]spermidine trihydrochloride from N-terminal 6his tagged TEV fused human DHPS expressed in Escherichia coli BL21 (DE3) incubated f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetDeoxyhypusine synthase(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50612292(CHEMBL5268272)
Affinity DataIC50: 26nMAssay Description:Displacement of [3H]spermidine trihydrochloride from N-terminal 6his tagged TEV fused human DHPS expressed in Escherichia coli BL21 (DE3) incubated f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetDeoxyhypusine synthase(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50612295(CHEMBL5267547)
Affinity DataIC50: 29nMAssay Description:Displacement of [3H]spermidine trihydrochloride from N-terminal 6his tagged TEV fused human DHPS expressed in Escherichia coli BL21 (DE3) incubated f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetDeoxyhypusine synthase(Rat)
National Institute of Dental Research

Curated by ChEMBL
LigandPNGBDBM50216786(N-(7-Amino-heptyl)-guanidine | N-guanyl-1,7-diamin...)
Affinity DataIC50: 30nMAssay Description:In vitro IC50 value by measuring the inhibition of deoxyhypusine synthase.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDeoxyhypusine synthase(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50612291(CHEMBL5278471)
Affinity DataIC50: 30nMAssay Description:Displacement of [3H]spermidine trihydrochloride from N-terminal 6his tagged TEV fused human DHPS expressed in Escherichia coli BL21 (DE3) incubated f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetDeoxyhypusine synthase(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50583911(CHEMBL5079375)
Affinity DataIC50: 40nMAssay Description:Inhibition of DHPS (unknown origin ) incubated for 30 mins by NAD/NADH-Glow assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetDeoxyhypusine synthase(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50583914(CHEMBL5074971)
Affinity DataIC50: 50nMAssay Description:Inhibition of DHPS (unknown origin ) incubated for 30 mins by NAD/NADH-Glow assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetDeoxyhypusine synthase(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50514710(CHEMBL4555677)
Affinity DataIC50: 62nMAssay Description:Inhibition of human N-terminal His6-tagged TEV protease site linked DHPS expressed in Escherichia coli BL21 (DE3) assessed as reduction in radiolabel...More data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetDeoxyhypusine synthase(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50514710(CHEMBL4555677)
Affinity DataIC50: 62nMAssay Description:Displacement of [3H]spermidine trihydrochloride from N-terminal 6his tagged TEV fused human DHPS expressed in Escherichia coli BL21 (DE3) incubated f...More data for this Ligand-Target Pair
In DepthDetails
PubMedPDB3D3D Structure (crystal)
TargetDeoxyhypusine synthase(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50612294(CHEMBL5281395)
Affinity DataIC50: 69nMAssay Description:Displacement of [3H]spermidine trihydrochloride from N-terminal 6his tagged TEV fused human DHPS expressed in Escherichia coli BL21 (DE3) incubated f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetDeoxyhypusine synthase(Rat)
National Institute of Dental Research

Curated by ChEMBL
LigandPNGBDBM50032510(N-[7-(7-Guanidino-heptylamino)-heptyl]-guanidine |...)
Affinity DataIC50: 80nMAssay Description:In vitro IC50 value by measuring the inhibition of deoxyhypusine synthase.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDeoxyhypusine synthase(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50514715(CHEMBL4543218)
Affinity DataIC50: 92nMAssay Description:Inhibition of human N-terminal His6-tagged TEV protease site linked DHPS expressed in Escherichia coli BL21 (DE3) assessed as reduction in radiolabel...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetDeoxyhypusine synthase(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50583906(CHEMBL5075342)
Affinity DataIC50: 100nMAssay Description:Inhibition of DHPS (unknown origin ) incubated for 30 mins by NAD/NADH-Glow assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetDeoxyhypusine synthase(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50612289(CHEMBL5282634)
Affinity DataIC50: 110nMAssay Description:Displacement of [3H]spermidine trihydrochloride from N-terminal 6his tagged TEV fused human DHPS expressed in Escherichia coli BL21 (DE3) incubated f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetDeoxyhypusine synthase(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50514717(CHEMBL4462702)
Affinity DataIC50: 120nMAssay Description:Inhibition of human N-terminal His6-tagged TEV protease site linked DHPS expressed in Escherichia coli BL21 (DE3) assessed as reduction in radiolabel...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetDeoxyhypusine synthase(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50216786(N-(7-Amino-heptyl)-guanidine | N-guanyl-1,7-diamin...)
Affinity DataIC50: 140nMAssay Description:Inhibition of human N-terminal His6-tagged TEV protease site linked DHPS expressed in Escherichia coli BL21 (DE3) assessed as reduction in radiolabel...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDeoxyhypusine synthase(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50612288(CHEMBL5281552)
Affinity DataIC50: 150nMAssay Description:Displacement of [3H]spermidine trihydrochloride from N-terminal 6his tagged TEV fused human DHPS expressed in Escherichia coli BL21 (DE3) incubated f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetDeoxyhypusine synthase(Rat)
National Institute of Dental Research

Curated by ChEMBL
LigandPNGBDBM50032469(N-[4-(4-Amino-butylamino)-butyl]-guanidine | CHEMB...)
Affinity DataIC50: 160nMAssay Description:In vitro IC50 value by measuring the inhibition of deoxyhypusine synthase.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDeoxyhypusine synthase(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50612286(CHEMBL5287156)
Affinity DataIC50: 160nMAssay Description:Displacement of [3H]spermidine trihydrochloride from N-terminal 6his tagged TEV fused human DHPS expressed in Escherichia coli BL21 (DE3) incubated f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetDeoxyhypusine synthase(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50612290(CHEMBL5288132)
Affinity DataIC50: 170nMAssay Description:Displacement of [3H]spermidine trihydrochloride from N-terminal 6his tagged TEV fused human DHPS expressed in Escherichia coli BL21 (DE3) incubated f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetDeoxyhypusine synthase(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50583898(CHEMBL5084409)
Affinity DataIC50: 180nMAssay Description:Inhibition of DHPS (unknown origin ) incubated for 30 mins by NAD/NADH-Glow assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetDeoxyhypusine synthase(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50583902(CHEMBL5091281)
Affinity DataIC50: 180nMAssay Description:Inhibition of DHPS (unknown origin ) incubated for 30 mins by NAD/NADH-Glow assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetDeoxyhypusine synthase(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50612293(CHEMBL5265996)
Affinity DataIC50: 230nMAssay Description:Displacement of [3H]spermidine trihydrochloride from N-terminal 6his tagged TEV fused human DHPS expressed in Escherichia coli BL21 (DE3) incubated f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetDeoxyhypusine synthase(Rat)
National Institute of Dental Research

Curated by ChEMBL
LigandPNGBDBM50032467(N-[7-(7-Amino-heptylamino)-heptyl]-guanidine | CHE...)
Affinity DataIC50: 300nMAssay Description:In vitro IC50 value by measuring the inhibition of deoxyhypusine synthase.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDeoxyhypusine synthase(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50583900(CHEMBL5090481)
Affinity DataIC50: 320nMAssay Description:Inhibition of DHPS (unknown origin ) incubated for 30 mins by NAD/NADH-Glow assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetDeoxyhypusine synthase(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50583895(CHEMBL5078063)
Affinity DataIC50: 330nMAssay Description:Inhibition of DHPS (unknown origin ) incubated for 30 mins by NAD/NADH-Glow assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetDeoxyhypusine synthase(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50612285(CHEMBL5269564)
Affinity DataIC50: 410nMAssay Description:Displacement of [3H]spermidine trihydrochloride from N-terminal 6his tagged TEV fused human DHPS expressed in Escherichia coli BL21 (DE3) incubated f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetDeoxyhypusine synthase(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50514706(CHEMBL4442298)
Affinity DataIC50: 430nMAssay Description:Inhibition of human N-terminal His6-tagged TEV protease site linked DHPS expressed in Escherichia coli BL21 (DE3) assessed as reduction in radiolabel...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetDeoxyhypusine synthase(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50612284(CHEMBL5283409)
Affinity DataIC50: 440nMAssay Description:Displacement of [3H]spermidine trihydrochloride from N-terminal 6his tagged TEV fused human DHPS expressed in Escherichia coli BL21 (DE3) incubated f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetDeoxyhypusine synthase(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50216786(N-(7-Amino-heptyl)-guanidine | N-guanyl-1,7-diamin...)
Affinity DataIC50: 500nMAssay Description:Competitive inhibition of human N-terminal His6-tagged TEV protease site linked DHPS expressed in Escherichia coli BL21 (DE3) assessed as reduction i...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDeoxyhypusine synthase(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50583915(CHEMBL5091279)
Affinity DataIC50: 530nMAssay Description:Inhibition of DHPS (unknown origin ) incubated for 30 mins by NAD/NADH-Glow assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetDeoxyhypusine synthase(Rat)
National Institute of Dental Research

Curated by ChEMBL
LigandPNGBDBM50032485(N-(8-Amino-octyl)-guanidine | CHEMBL101419)
Affinity DataIC50: 550nMAssay Description:In vitro IC50 value by measuring the inhibition of deoxyhypusine synthase.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDeoxyhypusine synthase(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50583889(CHEMBL5070084)
Affinity DataIC50: 560nMAssay Description:Inhibition of DHPS (unknown origin ) incubated for 30 mins by NAD/NADH-Glow assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetDeoxyhypusine synthase(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50612291(CHEMBL5278471)
Affinity DataIC50: 580nMAssay Description:Displacement of [3H]spermidine trihydrochloride from N-terminal 6his tagged TEV fused human DHPS expressed in Escherichia coli BL21 (DE3) incubated f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetDeoxyhypusine synthase(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50612295(CHEMBL5267547)
Affinity DataIC50: 630nMAssay Description:Displacement of [3H]spermidine trihydrochloride from N-terminal 6his tagged TEV fused human DHPS expressed in Escherichia coli BL21 (DE3) incubated f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetDeoxyhypusine synthase(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50583908(CHEMBL5081296)
Affinity DataIC50: 640nMAssay Description:Inhibition of DHPS (unknown origin ) incubated for 30 mins by NAD/NADH-Glow assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetDeoxyhypusine synthase(Rat)
National Institute of Dental Research

Curated by ChEMBL
LigandPNGBDBM50032495(N-[3-(3-Amino-propoxy)-propyl]-guanidine | CHEMBL1...)
Affinity DataIC50: 700nMAssay Description:In vitro IC50 value by measuring the inhibition of deoxyhypusine synthase.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDeoxyhypusine synthase(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50612292(CHEMBL5268272)
Affinity DataIC50: 790nMAssay Description:Displacement of [3H]spermidine trihydrochloride from N-terminal 6his tagged TEV fused human DHPS expressed in Escherichia coli BL21 (DE3) incubated f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetDeoxyhypusine synthase(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50514699(CHEMBL4447948)
Affinity DataIC50: 840nMAssay Description:Inhibition of human N-terminal His6-tagged TEV protease site linked DHPS expressed in Escherichia coli BL21 (DE3) assessed as reduction in radiolabel...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDeoxyhypusine synthase(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50583899(CHEMBL5075319)
Affinity DataIC50: 1.17E+3nMAssay Description:Inhibition of DHPS (unknown origin ) incubated for 30 mins by NAD/NADH-Glow assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetDeoxyhypusine synthase(Rat)
National Institute of Dental Research

Curated by ChEMBL
LigandPNGBDBM50032503(N-[3-(3-Amino-propylamino)-propyl]-guanidine | CHE...)
Affinity DataIC50: 1.20E+3nMAssay Description:In vitro IC50 value by measuring the inhibition of deoxyhypusine synthase.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDeoxyhypusine synthase(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50216786(N-(7-Amino-heptyl)-guanidine | N-guanyl-1,7-diamin...)
Affinity DataIC50: 1.72E+3nMAssay Description:Inhibition of DHPS (unknown origin ) incubated for 30 mins by NAD/NADH-Glow assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDeoxyhypusine synthase(Rat)
National Institute of Dental Research

Curated by ChEMBL
LigandPNGBDBM50032472(N-[3-(3-Amino-propylsulfanyl)-propyl]-guanidine | ...)
Affinity DataIC50: 1.90E+3nMAssay Description:In vitro IC50 value by measuring the inhibition of deoxyhypusine synthase.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDeoxyhypusine synthase(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50583888(CHEMBL5089864)
Affinity DataIC50: 2.29E+3nMAssay Description:Inhibition of DHPS (unknown origin ) incubated for 30 mins by NAD/NADH-Glow assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetDeoxyhypusine synthase(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50514698(CHEMBL4470208)
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of human N-terminal His6-tagged TEV protease site linked DHPS expressed in Escherichia coli BL21 (DE3) assessed as reduction in radiolabel...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
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