Compile Data Set for Download or QSAR
Report error Found 45 of ic50 data for polymerid = 50000465,50000974
TargetTryptase beta-2(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50131976(1-Acetyl-pyrrolidine-2-carboxylic acid [1-(benzoth...)
Affinity DataIC50: 2nMAssay Description:Inhibitory activity of compound was determined against human Tryptase betaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTryptase beta-2(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50167514([4-(3-Aminomethyl-phenyl)-piperidin-1-yl]-(1-butyl...)
Affinity DataIC50: 68nMAssay Description:Inhibition concentration against beta tryptase was determinedMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTryptase beta-2(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50524338(CHEMBL4468000)
Affinity DataIC50: 350nMAssay Description:Inhibition of tryptase-beta2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetTryptase beta-2(Mouse)
Weill Cornell Medicine

Curated by ChEMBL
LigandPNGBDBM50511189(CHEMBL4571556)
Affinity DataIC50: 455nMAssay Description:Inhibition of mouse MCP6 pre-incubated for 3 hrs before N-tert-butoxycarbonyl-Gln-Ala-Arg-AMC substrate addition and measured every 30 secs for 15 mi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetTryptase beta-2(Mouse)
Weill Cornell Medicine

Curated by ChEMBL
LigandPNGBDBM50511187(CHEMBL4542067)
Affinity DataIC50: 599nMAssay Description:Inhibition of mouse MCP6 pre-incubated for 3 hrs before N-tert-butoxycarbonyl-Gln-Ala-Arg-AMC substrate addition and measured every 30 secs for 15 mi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetTryptase beta-2(Mouse)
Weill Cornell Medicine

Curated by ChEMBL
LigandPNGBDBM50511190(CHEMBL4592202)
Affinity DataIC50: 1.14E+3nMAssay Description:Inhibition of mouse MCP6 pre-incubated for 3 hrs before N-tert-butoxycarbonyl-Gln-Ala-Arg-AMC substrate addition and measured every 30 secs for 15 mi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetTryptase beta-2(Mouse)
Weill Cornell Medicine

Curated by ChEMBL
LigandPNGBDBM50511191(CHEMBL4467543)
Affinity DataIC50: 1.42E+3nMAssay Description:Inhibition of mouse MCP6 pre-incubated for 3 hrs before N-tert-butoxycarbonyl-Gln-Ala-Arg-AMC substrate addition and measured every 30 secs for 15 mi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetTryptase beta-2(Mouse)
Weill Cornell Medicine

Curated by ChEMBL
LigandPNGBDBM50511179(CHEMBL4453049)
Affinity DataIC50: 1.55E+3nMAssay Description:Inhibition of mouse MCP6 pre-incubated for 3 hrs before N-tert-butoxycarbonyl-Gln-Ala-Arg-AMC substrate addition and measured every 30 secs for 15 mi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetTryptase beta-2(Mouse)
Weill Cornell Medicine

Curated by ChEMBL
LigandPNGBDBM50511186(CHEMBL4553079)
Affinity DataIC50: 2.16E+3nMAssay Description:Inhibition of mouse MCP6 pre-incubated for 3 hrs before N-tert-butoxycarbonyl-Gln-Ala-Arg-AMC substrate addition and measured every 30 secs for 15 mi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetTryptase beta-2(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50162761([4-Guanidino-1-((S)-4-{(S)-5-[4-((S)-4-guanidino-b...)
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibitory concentration against tryptaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTryptase beta-2(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50524345(CHEMBL4475961)
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of tryptase-beta2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetTryptase beta-2(Mouse)
Weill Cornell Medicine

Curated by ChEMBL
LigandPNGBDBM50511181(CHEMBL4464544)
Affinity DataIC50: 2.31E+3nMAssay Description:Inhibition of mouse MCP6 pre-incubated for 3 hrs before N-tert-butoxycarbonyl-Gln-Ala-Arg-AMC substrate addition and measured every 30 secs for 15 mi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetTryptase beta-2(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50162770(N-[4-Guanidino-1-((S)-4-{(S)-5-[4-((S)-4-guanidino...)
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibitory concentration against tryptaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTryptase beta-2(Mouse)
Weill Cornell Medicine

Curated by ChEMBL
LigandPNGBDBM50511182(CHEMBL4576109)
Affinity DataIC50: 2.54E+3nMAssay Description:Inhibition of mouse MCP6 pre-incubated for 3 hrs before N-tert-butoxycarbonyl-Gln-Ala-Arg-AMC substrate addition and measured every 30 secs for 15 mi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetTryptase beta-2(Mouse)
Weill Cornell Medicine

Curated by ChEMBL
LigandPNGBDBM50511180(CHEMBL4548912)
Affinity DataIC50: 2.89E+3nMAssay Description:Inhibition of mouse MCP6 pre-incubated for 3 hrs before N-tert-butoxycarbonyl-Gln-Ala-Arg-AMC substrate addition and measured every 30 secs for 15 mi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetTryptase beta-2(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50524344(CHEMBL4584532)
Affinity DataIC50: 3.30E+3nMAssay Description:Inhibition of tryptase-beta2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetTryptase beta-2(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50524347(CHEMBL4535197)
Affinity DataIC50: 3.30E+3nMAssay Description:Inhibition of tryptase-beta2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetTryptase beta-2(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50524340(CHEMBL4483713)
Affinity DataIC50: 3.60E+3nMAssay Description:Inhibition of tryptase-beta2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetTryptase beta-2(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50167514([4-(3-Aminomethyl-phenyl)-piperidin-1-yl]-(1-butyl...)
Affinity DataIC50: 3.69E+3nMAssay Description:Inhibitory concentration against alpha tryptase was determinedMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTryptase beta-2(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50462108(CHEMBL4246585)
Affinity DataIC50: 3.70E+3nMAssay Description:Inhibition of tryptase-beta2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetTryptase beta-2(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50162764([1-((S)-4-{(S)-5-[4-((S)-(S)-2-Benzyloxycarbonylam...)
Affinity DataIC50: 4.10E+3nMAssay Description:Inhibitory concentration against tryptaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTryptase beta-2(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50162760(4-Guanidino-N-[(S)-4-((S)-5-{4-[2-(2-imino-imidazo...)
Affinity DataIC50: 4.40E+3nMAssay Description:Inhibitory concentration against tryptaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTryptase beta-2(Mouse)
Weill Cornell Medicine

Curated by ChEMBL
LigandPNGBDBM50511192(CHEMBL4578086)
Affinity DataIC50: 4.69E+3nMAssay Description:Inhibition of mouse MCP6 pre-incubated for 3 hrs before N-tert-butoxycarbonyl-Gln-Ala-Arg-AMC substrate addition and measured every 30 secs for 15 mi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetTryptase beta-2(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50162758(4-Guanidino-N-(4-{(S)-5-[4-((S)-4-guanidino-butyry...)
Affinity DataIC50: 4.70E+3nMAssay Description:Inhibitory concentration against tryptaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTryptase beta-2(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50162762([(S)-4-Guanidino-1-((S)-4-{(S)-5-[4-(5-guanidino-p...)
Affinity DataIC50: 5.70E+3nMAssay Description:Inhibitory concentration against tryptaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTryptase beta-2(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50162763(N-((S)-4-{5-[4-(3-Guanidino-propionylamino)-butyl]...)
Affinity DataIC50: 5.90E+3nMAssay Description:Inhibitory concentration against tryptaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTryptase beta-2(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50524346(CHEMBL4548070)
Affinity DataIC50: 6.50E+3nMAssay Description:Inhibition of tryptase-beta2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTryptase beta-2(Mouse)
Weill Cornell Medicine

Curated by ChEMBL
LigandPNGBDBM50511184(CHEMBL4518997)
Affinity DataIC50: 7.43E+3nMAssay Description:Inhibition of mouse MCP6 pre-incubated for 3 hrs before N-tert-butoxycarbonyl-Gln-Ala-Arg-AMC substrate addition and measured every 30 secs for 15 mi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetTryptase beta-2(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50524339(CHEMBL4463116)
Affinity DataIC50: 8.70E+3nMAssay Description:Inhibition of tryptase-beta2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetTryptase beta-2(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50162759([1-(4-{(S)-5-[((S)-3-Carbamimidoyl-phenylcarbamoyl...)
Affinity DataIC50: 9.09E+3nMAssay Description:Inhibitory concentration against tryptaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTryptase beta-2(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50162765((S)-N-[4-Guanidino-1-((S)-4-{(S)-5-[4-(5-guanidino...)
Affinity DataIC50: 9.30E+3nMAssay Description:Inhibitory concentration against tryptaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTryptase beta-2(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50302107(Grassystatin A | CHEMBL567893)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of tryptase beta2 after 10 to 15 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTryptase beta-2(Mouse)
Weill Cornell Medicine

Curated by ChEMBL
LigandPNGBDBM50511183(CHEMBL4465979)
Affinity DataIC50: 1.17E+4nMAssay Description:Inhibition of mouse MCP6 pre-incubated for 3 hrs before N-tert-butoxycarbonyl-Gln-Ala-Arg-AMC substrate addition and measured every 30 secs for 15 mi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetTryptase beta-2(Mouse)
Weill Cornell Medicine

Curated by ChEMBL
LigandPNGBDBM50511185(CHEMBL4446603)
Affinity DataIC50: 1.18E+4nMAssay Description:Inhibition of mouse MCP6 pre-incubated for 3 hrs before N-tert-butoxycarbonyl-Gln-Ala-Arg-AMC substrate addition and measured every 30 secs for 15 mi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetTryptase beta-2(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50162769(N-[(S)-1-(4-{(S)-5-[((S)-3-Carbamimidoyl-phenylcar...)
Affinity DataIC50: 1.24E+4nMAssay Description:Inhibitory concentration against tryptaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTryptase beta-2(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50162766(N-((S)-4-{(S)-5-[(3-Carbamimidoyl-phenylcarbamoyl)...)
Affinity DataIC50: 1.28E+4nMAssay Description:Inhibitory concentration against tryptaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTryptase beta-2(Mouse)
Weill Cornell Medicine

Curated by ChEMBL
LigandPNGBDBM50511188(CHEMBL4461928)
Affinity DataIC50: 1.75E+4nMAssay Description:Inhibition of mouse MCP6 pre-incubated for 3 hrs before N-tert-butoxycarbonyl-Gln-Ala-Arg-AMC substrate addition and measured every 30 secs for 15 mi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetTryptase beta-2(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50162771(N-(3-Carbamimidoyl-phenyl)-2-{(2S,5S)-5-[4-(2-guan...)
Affinity DataIC50: 1.99E+4nMAssay Description:Inhibitory concentration against tryptaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTryptase beta-2(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50524342(CHEMBL4516604)
Affinity DataIC50: 2.10E+4nMAssay Description:Inhibition of tryptase-beta2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetTryptase beta-2(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50162768(N-((S)-4-{(S)-5-[(3-Carbamimidoyl-phenylcarbamoyl)...)
Affinity DataIC50: 2.13E+4nMAssay Description:Inhibitory concentration against tryptaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTryptase beta-2(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50162767(N-((S)-4-{(S)-5-[(3-Carbamimidoyl-phenylcarbamoyl)...)
Affinity DataIC50: 2.36E+4nMAssay Description:Inhibitory concentration against tryptaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTryptase beta-2(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50524343(CHEMBL4546264)
Affinity DataIC50: 5.50E+4nMAssay Description:Inhibition of tryptase-beta2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetTryptase beta-2(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50536834(CHEMBL4590201)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of tryptase beta2 (unknown origin) using Z-GPR-AMC as substrate preincubated for 20 mins followed by substrate addition by fluorescence pl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetTryptase beta-2(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50536839(CHEMBL2402203 | acs.jmedchem.1c00409_ST.724)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of tryptase beta2 (unknown origin) using Z-GPR-AMC as substrate preincubated for 20 mins followed by substrate addition by fluorescence pl...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTryptase beta-2(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50536838(CHEMBL4520267)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of tryptase beta2 (unknown origin) using Z-GPR-AMC as substrate preincubated for 20 mins followed by substrate addition by fluorescence pl...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed