Compile Data Set for Download or QSAR
Report error Found 7 of ic50 data for polymerid = 50000408
TargetCyclin-dependent kinase 18(Human)
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM2579(CHEMBL388978 | Staurosporine, 8 | Staurosporin, 4 ...)
Affinity DataIC50: 66.3nMAssay Description:Inhibition of human CDK18/cyclin-Y using RB protein as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCyclin-dependent kinase 18(Human)
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50593922(CHEMBL5199065)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of CDK18 (unknown origin) incubated for 120 mins in presence of ATP by HotSpot kinase assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetCyclin-dependent kinase 18(Human)
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50404389(CHEMBL5285499)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of CDK18 (unknown origin) incubated for 120 mins in presence of ATP by HotSpot kinase assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetCyclin-dependent kinase 18(Human)
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM126500(US8778951, 310 | US11591322, Compound NVP-2)
Affinity DataIC50: 4.90E+3nMAssay Description:Inhibition of CDK18 (unknown origin) by Kinomescan methodMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetCyclin-dependent kinase 18(Human)
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50539721(CHEMBL4635959)
Affinity DataIC50: 8.00E+3nMAssay Description:Inhibition of CDK18 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCyclin-dependent kinase 18(Human)
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50519662(CHEMBL4438748)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant full length human cyclinY/CDK18 T166M mutant using YRRAAVPPSPSLS as substrate measured after 40 mins in presence of [gamma3...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCyclin-dependent kinase 18(Human)
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50593922(CHEMBL5199065)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of human CDK18/Cyclin Y preincubated for 20 mins followed by 32P-ATP addition and measured after 2 hrs in presence of 20 uM ATPMore data for this Ligand-Target Pair
In DepthDetails
PubMed