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LigandPNGBDBM277687(5-((2-(3-((4-((4-(3-(5-(tert-Butyl)-2-methoxy-3-me...)
Affinity DataIC50: 2.80nMAssay Description:PBMCs from healthy subjects are separated from whole blood using a density gradient (Lymphoprep, Axis-Shield Healthcare). Cells are added to a 96 wel...More data for this Ligand-Target Pair
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LigandPNGBDBM277693(2-((2-(2-(3-((4-((4-(3-(5-(tert-Butyl)-2-methoxy-3...)
Affinity DataIC50: 2.90nMAssay Description:PBMCs from healthy subjects are separated from whole blood using a density gradient (Lymphoprep, Axis-Shield Healthcare). Cells are added to a 96 wel...More data for this Ligand-Target Pair
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LigandPNGBDBM277686(5-((2-(3-((4-((4-(3-(5-(tert-Butyl)-2-methoxy-3-(m...)
Affinity DataIC50: 5.60nMAssay Description:PBMCs from healthy subjects are separated from whole blood using a density gradient (Lymphoprep, Axis-Shield Healthcare). Cells are added to a 96 wel...More data for this Ligand-Target Pair
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LigandPNGBDBM277702(5-((2-(3-((4-((4-(3-(5-tert-Butyl)-2-methoxy-3-(me...)
Affinity DataIC50: 7.30nMAssay Description:PBMCs from healthy subjects are separated from whole blood using a density gradient (Lymphoprep, Axis-Shield Healthcare). Cells are added to a 96 wel...More data for this Ligand-Target Pair
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LigandPNGBDBM277688(2-(2-(2-(3-((4-((4-(3-(5-(tert-Butyl-2-methoxy-3-(...)
Affinity DataIC50: 7.30nMAssay Description:PBMCs from healthy subjects are separated from whole blood using a density gradient (Lymphoprep, Axis-Shield Healthcare). Cells are added to a 96 wel...More data for this Ligand-Target Pair
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LigandPNGBDBM13066({2-[(2,6-dichlorophenyl)amino]phenyl}acetic acid |...)
Affinity DataIC50: 8nMAssay Description:Inhibition of CXCL8-induced chemotaxis in human polymorphonuclear leukocyte pretreated for 15 mins measured after 4 hrs by cell migration assayMore data for this Ligand-Target Pair
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LigandPNGBDBM277682(2-(2-(2-(3-((4-((4-(3-(5-(tert-Butyl)-2-methoxy)-3...)
Affinity DataIC50: 8nMAssay Description:PBMCs from healthy subjects are separated from whole blood using a density gradient (Lymphoprep, Axis-Shield Healthcare). Cells are added to a 96 wel...More data for this Ligand-Target Pair
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LigandPNGBDBM50295276(2-(2-(2-fluorophenylamino)phenyl)acetic acid | CHE...)
Affinity DataIC50: 9nMAssay Description:Inhibition of CXCL8-induced chemotaxis in human polymorphonuclear leukocyte pretreated for 15 mins measured after 4 hrs by cell migration assayMore data for this Ligand-Target Pair
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LigandPNGBDBM50295266(2-{2-[(2,6-Dichlorophenyl)amino]phenyl}propanoic a...)
Affinity DataIC50: 10nMAssay Description:Inhibition of CXCL8-induced chemotaxis in human polymorphonuclear leukocyte pretreated for 15 mins measured after 4 hrs by cell migration assayMore data for this Ligand-Target Pair
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LigandPNGBDBM277694(US10072034, Example 20(a) | US10072034, Example 20...)
Affinity DataIC50: 10.4nMAssay Description:PBMCs from healthy subjects are separated from whole blood using a density gradient (Lymphoprep, Axis-Shield Healthcare). Cells are added to a 96 wel...More data for this Ligand-Target Pair
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LigandPNGBDBM277683(2-(2-(2-(3-((4-((4-(3-(5-(tert-Butyl)-2-methoxy-3-...)
Affinity DataIC50: 11.7nMAssay Description:PBMCs from healthy subjects are separated from whole blood using a density gradient (Lymphoprep, Axis-Shield Healthcare). Cells are added to a 96 wel...More data for this Ligand-Target Pair
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LigandPNGBDBM277685(2-(2-(2-(3-((4-((4-(3-(5-(tert-Butyl)-2-methoxy-3-...)
Affinity DataIC50: 11.7nMAssay Description:PBMCs from healthy subjects are separated from whole blood using a density gradient (Lymphoprep, Axis-Shield Healthcare). Cells are added to a 96 wel...More data for this Ligand-Target Pair
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LigandPNGBDBM50295267(2-{2-[(2,6-Dichlorophenyl)amino]phenyl}propanamide...)
Affinity DataIC50: 12nMAssay Description:Inhibition of CXCL8-induced chemotaxis in human polymorphonuclear leukocyte pretreated for 15 mins measured after 4 hrs by cell migration assayMore data for this Ligand-Target Pair
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LigandPNGBDBM50295281(2-(2-(2-fluorophenoxy)phenyl)acetic acid | [2-(2-F...)
Affinity DataIC50: 13nMAssay Description:Inhibition of CXCL8-induced chemotaxis in human polymorphonuclear leukocyte pretreated for 15 mins measured after 4 hrs by cell migration assayMore data for this Ligand-Target Pair
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LigandPNGBDBM50295268(2-{2-[(2,6-Dichlorophenyl)amino]phenyl}-N-(methyls...)
Affinity DataIC50: 13nMAssay Description:Inhibition of CXCL8-induced chemotaxis in human polymorphonuclear leukocyte pretreated for 15 mins measured after 4 hrs by cell migration assayMore data for this Ligand-Target Pair
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LigandPNGBDBM277696(2-(2-(2-(3-((4-((4-(3-(5-(tert-Butyl)-2-methoxy-3-...)
Affinity DataIC50: 14.4nMAssay Description:PBMCs from healthy subjects are separated from whole blood using a density gradient (Lymphoprep, Axis-Shield Healthcare). Cells are added to a 96 wel...More data for this Ligand-Target Pair
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LigandPNGBDBM277701(5-((2-(3-((4-((4-(3-(5-(tert-Butyl)-2-methoxy-3-(m...)
Affinity DataIC50: 15.3nMAssay Description:PBMCs from healthy subjects are separated from whole blood using a density gradient (Lymphoprep, Axis-Shield Healthcare). Cells are added to a 96 wel...More data for this Ligand-Target Pair
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LigandPNGBDBM277690(2-(2-(2-(3-((4-((4-(3-(5-(tert-Butyl)-3-(ethylsulf...)
Affinity DataIC50: 16.3nMAssay Description:PBMCs from healthy subjects are separated from whole blood using a density gradient (Lymphoprep, Axis-Shield Healthcare). Cells are added to a 96 wel...More data for this Ligand-Target Pair
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LigandPNGBDBM277689(2-(2-(2-(3-((4-((4-(3-(5-(tert-Butyl-3-(ethylsulfo...)
Affinity DataIC50: 16.4nMAssay Description:PBMCs from healthy subjects are separated from whole blood using a density gradient (Lymphoprep, Axis-Shield Healthcare). Cells are added to a 96 wel...More data for this Ligand-Target Pair
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LigandPNGBDBM277691(2-(2-(2-(3-((4-((4-(3-(5-(tert-Butyl) isoxazol-3-y...)
Affinity DataIC50: 17.2nMAssay Description:PBMCs from healthy subjects are separated from whole blood using a density gradient (Lymphoprep, Axis-Shield Healthcare). Cells are added to a 96 wel...More data for this Ligand-Target Pair
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LigandPNGBDBM277677(2-(2-(2-(3-((4-((4-(3-(5-(tert-Butyl)-2-methoxy)-3...)
Affinity DataIC50: 17.3nMAssay Description:PBMCs from healthy subjects are separated from whole blood using a density gradient (Lymphoprep, Axis-Shield Healthcare). Cells are added to a 96 wel...More data for this Ligand-Target Pair
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LigandPNGBDBM277680(2-(2-(2-(3-((4-((4-(3-(5-tert-Butyl-2-methoxy-3-(m...)
Affinity DataIC50: 18.1nMAssay Description:PBMCs from healthy subjects are separated from whole blood using a density gradient (Lymphoprep, Axis-Shield Healthcare). Cells are added to a 96 wel...More data for this Ligand-Target Pair
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LigandPNGBDBM277697(1-(2-(2-(3-((4-((4-(3-(5-(tert-Butyl)-2-methoxy-3-...)
Affinity DataIC50: 18.1nMAssay Description:PBMCs from healthy subjects are separated from whole blood using a density gradient (Lymphoprep, Axis-Shield Healthcare). Cells are added to a 96 wel...More data for this Ligand-Target Pair
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LigandPNGBDBM277694(US10072034, Example 20(a) | US10072034, Example 20...)
Affinity DataIC50: 19.1nMAssay Description:PBMCs from healthy subjects are separated from whole blood using a density gradient (Lymphoprep, Axis-Shield Healthcare). Cells are added to a 96 wel...More data for this Ligand-Target Pair
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LigandPNGBDBM277679(2-(2-(2-(3-((4-((4-(3-(5-(tert-Butyl)-2-(methoxy-d...)
Affinity DataIC50: 19.5nMAssay Description:PBMCs from healthy subjects are separated from whole blood using a density gradient (Lymphoprep, Axis-Shield Healthcare). Cells are added to a 96 wel...More data for this Ligand-Target Pair
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LigandPNGBDBM50169048((R)-2-(3-Benzoylphenyl)propionic acid | (R)-2-(3-b...)
Affinity DataIC50: 20nMAssay Description:Inhibition of CXCL8-induced chemotaxis in human polymorphonuclear leukocyte pretreated for 15 mins measured after 4 hrs by cell migration assayMore data for this Ligand-Target Pair
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LigandPNGBDBM50295270(2-{2-[(2,6-Dichlorophenyl)amino]phenyl}-N-(2-hydro...)
Affinity DataIC50: 20nMAssay Description:Inhibition of CXCL8-induced chemotaxis in human polymorphonuclear leukocyte pretreated for 15 mins measured after 4 hrs by cell migration assayMore data for this Ligand-Target Pair
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LigandPNGBDBM277703(2-(2-(2-(3-((4-((4-(3-(5-(tert-Butyl)-2-methoxy-3-...)
Affinity DataIC50: 20.6nMAssay Description:PBMCs from healthy subjects are separated from whole blood using a density gradient (Lymphoprep, Axis-Shield Healthcare). Cells are added to a 96 wel...More data for this Ligand-Target Pair
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LigandPNGBDBM277681(2-(2-(2-(3-(4-((4-(3-(5-(tert-Butyl)-2-methoxy-3-(...)
Affinity DataIC50: 20.8nMAssay Description:PBMCs from healthy subjects are separated from whole blood using a density gradient (Lymphoprep, Axis-Shield Healthcare). Cells are added to a 96 wel...More data for this Ligand-Target Pair
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LigandPNGBDBM277676(2-(2-(2-(3-((4-((4-(3-(5-(tert-Butyl)-2-methoxy-3-...)
Affinity DataIC50: 24.6nMAssay Description:PBMCs from healthy subjects are separated from whole blood using a density gradient (Lymphoprep, Axis-Shield Healthcare). Cells are added to a 96 wel...More data for this Ligand-Target Pair
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LigandPNGBDBM50090679([2-(2,5-Dichloro-phenylamino)-phenyl]-acetic acid ...)
Affinity DataIC50: 25nMAssay Description:Inhibition of CXCL8-induced chemotaxis in human polymorphonuclear leukocyte pretreated for 15 mins measured after 4 hrs by cell migration assayMore data for this Ligand-Target Pair
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LigandPNGBDBM50295269(2-{2-[(2,6-Dichlorophenyl)amino]phenyl}-N,N'-[3,3-...)
Affinity DataIC50: 25nMAssay Description:Inhibition of CXCL8-induced chemotaxis in human polymorphonuclear leukocyte pretreated for 15 mins measured after 4 hrs by cell migration assayMore data for this Ligand-Target Pair
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LigandPNGBDBM277700(2-(2-(2-(3-((4-((4-(3-(5-(tert-Butyl-2-methoxy-3-(...)
Affinity DataIC50: 26.3nMAssay Description:PBMCs from healthy subjects are separated from whole blood using a density gradient (Lymphoprep, Axis-Shield Healthcare). Cells are added to a 96 wel...More data for this Ligand-Target Pair
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LigandPNGBDBM277684(2-(2-(2-(3-((4-((4-(3-(5-(tert-Butyl)-3-(dimethylp...)
Affinity DataIC50: 26.5nMAssay Description:PBMCs from healthy subjects are separated from whole blood using a density gradient (Lymphoprep, Axis-Shield Healthcare). Cells are added to a 96 wel...More data for this Ligand-Target Pair
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LigandPNGBDBM277698(N-(3-(3-(4-((2-((3-(2-(2-(1H-Tetrazol-5-yl)methoxy...)
Affinity DataIC50: 29.2nMAssay Description:PBMCs from healthy subjects are separated from whole blood using a density gradient (Lymphoprep, Axis-Shield Healthcare). Cells are added to a 96 wel...More data for this Ligand-Target Pair
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LigandPNGBDBM277692(N-(5-(tert-Butl-2-methoxy-3-(3-(4-((2-((3-methoxy-...)
Affinity DataIC50: 29.3nMAssay Description:PBMCs from healthy subjects are separated from whole blood using a density gradient (Lymphoprep, Axis-Shield Healthcare). Cells are added to a 96 wel...More data for this Ligand-Target Pair
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LigandPNGBDBM17638(indometacin | Indocin | 2-{1-[(4-chlorophenyl)carb...)
Affinity DataIC50: 50nMAssay Description:Inhibition of CXCL8-induced chemotaxis in human polymorphonuclear leukocyte pretreated for 15 mins measured after 4 hrs by cell migration assayMore data for this Ligand-Target Pair
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LigandPNGBDBM50295283(2-[2-(2-Fluorophenoxy)phenyl]-N-(methylsulfonyl)ac...)
Affinity DataIC50: 50nMAssay Description:Inhibition of CXCL8-induced chemotaxis in human polymorphonuclear leukocyte pretreated for 15 mins measured after 4 hrs by cell migration assayMore data for this Ligand-Target Pair
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LigandPNGBDBM50169044((2R)-2-[4-(2-methylpropyl)phenyl]propanoic acid | ...)
Affinity DataIC50: 50nMAssay Description:Inhibition of CXCL8-induced chemotaxis in human polymorphonuclear leukocyte pretreated for 15 mins measured after 4 hrs by cell migration assayMore data for this Ligand-Target Pair
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LigandPNGBDBM277699(2-(2-(3-((4-((4-(3-(5-(tert-Buty-2-methoxy-3-(meth...)
Affinity DataIC50: 61.9nMAssay Description:PBMCs from healthy subjects are separated from whole blood using a density gradient (Lymphoprep, Axis-Shield Healthcare). Cells are added to a 96 wel...More data for this Ligand-Target Pair
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LigandPNGBDBM50295287(2-(1-methyl-5-(4-methylbenzoyl)-1H-pyrrol-2-yl)ace...)
Affinity DataIC50: 90nMAssay Description:Inhibition of CXCL8-induced chemotaxis in human polymorphonuclear leukocyte pretreated for 15 mins measured after 4 hrs by cell migration assayMore data for this Ligand-Target Pair
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LigandPNGBDBM277678(2-(2-(2-(3-((4-((4-(3-(5-(tert-Butyl)-2-methoxy-3-...)
Affinity DataIC50: 115nMAssay Description:PBMCs from healthy subjects are separated from whole blood using a density gradient (Lymphoprep, Axis-Shield Healthcare). Cells are added to a 96 wel...More data for this Ligand-Target Pair
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LigandPNGBDBM50295275([2-(2-Chloro-phenylamino)-phenyl]-acetic acid | 2-...)
Affinity DataIC50: 400nMAssay Description:Inhibition of CXCL8-induced chemotaxis in human polymorphonuclear leukocyte pretreated for 15 mins measured after 4 hrs by cell migration assayMore data for this Ligand-Target Pair
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LigandPNGBDBM50295282([2-(2-Chloro-phenoxy)-phenyl]-acetic acid | 2-(2-(...)
Affinity DataIC50: 500nMAssay Description:Inhibition of CXCL8-induced chemotaxis in human polymorphonuclear leukocyte pretreated for 15 mins measured after 4 hrs by cell migration assayMore data for this Ligand-Target Pair
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LigandPNGBDBM50295274(2-(2-(2,6-dichloro-3-methylphenylamino)phenyl)acet...)
Affinity DataIC50: 500nMAssay Description:Inhibition of CXCL8-induced chemotaxis in human polymorphonuclear leukocyte pretreated for 15 mins measured after 4 hrs by cell migration assayMore data for this Ligand-Target Pair
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LigandPNGBDBM59542(SMR000523991 | cid_1088438 | MLS001201458 | 1-(4-m...)
Affinity DataIC50: 551nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...More data for this Ligand-Target Pair
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LigandPNGBDBM59542(SMR000523991 | cid_1088438 | MLS001201458 | 1-(4-m...)
Affinity DataIC50: 596nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...More data for this Ligand-Target Pair
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LigandPNGBDBM50295271(2-{2-[(2,6-Dichlorophenyl)amino]phenyl}-N-(2,6-dim...)
Affinity DataIC50: 600nMAssay Description:Inhibition of CXCL8-induced chemotaxis in human polymorphonuclear leukocyte pretreated for 15 mins measured after 4 hrs by cell migration assayMore data for this Ligand-Target Pair
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LigandPNGBDBM50295272(N-(tert-Butyl)-2-{2-[(2,6-dichlorophenyl)amino]phe...)
Affinity DataIC50: 650nMAssay Description:Inhibition of CXCL8-induced chemotaxis in human polymorphonuclear leukocyte pretreated for 15 mins measured after 4 hrs by cell migration assayMore data for this Ligand-Target Pair
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LigandPNGBDBM50295285(Ibufenac | (4-Isobutyl-phenyl)-acetic acid | 2-(4-...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of CXCL8-induced chemotaxis in human polymorphonuclear leukocyte pretreated for 15 mins measured after 4 hrs by cell migration assayMore data for this Ligand-Target Pair
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