Compile Data Set for Download or QSAR
Report error Found 1059 of ic50 data for polymerid = 50000059
TargetAcyl-CoA:cholesterol acyltransferase(Rabbit)
TBA

Curated by ChEMBL
LigandPNGBDBM50289051(N-(2,6-Diisopropyl-phenyl)-malonamic acid (R)-1-me...)
Affinity DataIC50: 4nMAssay Description:In vitro inhibitory activity against Acyl coenzyme A:cholesterol acyltransferase in intestinal microsomes isolated from cholesterol fed rabbits (IAI)...More data for this Ligand-Target Pair
In DepthDetails Article

TargetAcyl-CoA:cholesterol acyltransferase(Rabbit)
TBA

Curated by ChEMBL
LigandPNGBDBM50289025(N-(2,6-Diisopropyl-phenyl)-malonamic acid (S)-1-me...)
Affinity DataIC50: 4nMAssay Description:In vitro inhibitory activity against Acyl coenzyme A:cholesterol acyltransferase in intestinal microsomes isolated from cholesterol fed rabbits (IAI)...More data for this Ligand-Target Pair
In DepthDetails Article

TargetAcyl-CoA:cholesterol acyltransferase(Rabbit)
TBA

Curated by ChEMBL
LigandPNGBDBM50079715(Tetradecanethioic acid (2,6-diisopropyl-phenyl)-am...)
Affinity DataIC50: 6nMAssay Description:Compound was tested for inhibitory activity against ACAT from rabbit intestineMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAcyl-CoA:cholesterol acyltransferase(Rabbit)
TBA

Curated by ChEMBL
LigandPNGBDBM50289024(N-(2,6-Diisopropyl-phenyl)-malonamic acid 1-methyl...)
Affinity DataIC50: 6nMAssay Description:In vitro inhibitory activity against Acyl coenzyme A:cholesterol acyltransferase in intestinal microsomes isolated from cholesterol fed rabbits (IAI)...More data for this Ligand-Target Pair
In DepthDetails Article

TargetAcyl-CoA:cholesterol acyltransferase(Rabbit)
TBA

Curated by ChEMBL
LigandPNGBDBM50045906(3-Oxo-hexadecanoic acid (2,6-diisopropyl-phenyl)-a...)
Affinity DataIC50: 6nMAssay Description:In vitro inhibition of Acyl coenzyme A:cholesterol acyltransferase in intestinal microsomes isolated from cholesterol-fed rabbitsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAcyl-CoA:cholesterol acyltransferase(Rabbit)
TBA

Curated by ChEMBL
LigandPNGBDBM50069886((2,6-Diisopropyl-phenylcarbamoyl)-methanesulfonic ...)
Affinity DataIC50: 7nMAssay Description:In vitro inhibition of ACAT by incubation with [1-14C]oleolyl-CoA and intestinal microsomes isolated from cholesterol-fed rabbits.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAcyl-CoA:cholesterol acyltransferase(Rabbit)
TBA

Curated by ChEMBL
LigandPNGBDBM50069883((2,6-Diisopropyl-phenylcarbamoyl)-methanesulfonic ...)
Affinity DataIC50: 7nMAssay Description:In vitro inhibition of ACAT by incubation with [1-14C]oleolyl-CoA and intestinal microsomes isolated from cholesterol-fed rabbits.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAcyl-CoA:cholesterol acyltransferase(Rabbit)
TBA

Curated by ChEMBL
LigandPNGBDBM50040815(2-Methylsulfanyl-6,11-dihydro-dibenzo[b,e]oxepine-...)
Affinity DataIC50: 7nMAssay Description:In vitro inhibitory activity against acyl coenzyme A:cholesterol acyltransferase in liver microsomes isolated from cholesterol-fed rabbitsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAcyl-CoA:cholesterol acyltransferase(Rabbit)
TBA

Curated by ChEMBL
LigandPNGBDBM50005955(CHEMBL40608 | Octadec-9-enoic acid (2,6-diisopropy...)
Affinity DataIC50: 7nMAssay Description:In vitro inhibition of acyl coenzyme A:cholesterol acyltransferase, in intestinal microsomes isolated from cholesterol-fed rabbitsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAcyl-CoA:cholesterol acyltransferase(Rabbit)
TBA

Curated by ChEMBL
LigandPNGBDBM50039427(+/-(1-Methyl-Tridecyl)Thiocarbonyl-carbamic acid 2...)
Affinity DataIC50: 8nMAssay Description:In vitro Acyl coenzyme A:cholesterol acyltransferase inhibitory activity (IAI) was determined by measuring the incorporation of [1-14C]oleolyl-CoA in...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAcyl-CoA:cholesterol acyltransferase(Rabbit)
TBA

Curated by ChEMBL
LigandPNGBDBM50051460(2-(2-Dodecyl-2H-tetrazol-5-yl)-2-phenyl-N-(2,4,6-t...)
Affinity DataIC50: 8nMAssay Description:Inhibitory concentration against Acyl coenzyme A:cholesterol acyltransferase 1 from rabbit intestineMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAcyl-CoA:cholesterol acyltransferase(Rabbit)
TBA

Curated by ChEMBL
LigandPNGBDBM50281484(1-(2,6-Diisopropyl-phenyl)-3-(4-undecyl-phenyl)-ur...)
Affinity DataIC50: 9nMAssay Description:In vitro inhibition of intestinal Acyl coenzyme A:cholesterol acyltransferase in cholesterol-fed rabbits.More data for this Ligand-Target Pair
In DepthDetails Article

TargetAcyl-CoA:cholesterol acyltransferase(Rabbit)
TBA

Curated by ChEMBL
LigandPNGBDBM50281487(1-(2,6-Diisopropyl-phenyl)-3-(4-nonyl-phenyl)-urea...)
Affinity DataIC50: 9nMAssay Description:In vitro inhibition of intestinal Acyl coenzyme A:cholesterol acyltransferase in cholesterol-fed rabbits.More data for this Ligand-Target Pair
In DepthDetails Article

TargetAcyl-CoA:cholesterol acyltransferase(Rabbit)
TBA

Curated by ChEMBL
LigandPNGBDBM50039428(Tridecyloxycarbonyl-carbamic acid 2,6-diisopropyl-...)
Affinity DataIC50: 9nMAssay Description:In vitro Acyl coenzyme A:cholesterol acyltransferase inhibitory activity (IAI) was determined by measuring the incorporation of [1-14C]oleolyl-CoA in...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAcyl-CoA:cholesterol acyltransferase(Rabbit)
TBA

Curated by ChEMBL
LigandPNGBDBM50054305(1-(2,6-Diisopropyl-phenyl)-3-(2-undecyl-2,3-dihydr...)
Affinity DataIC50: 9nMAssay Description:Acyl coenzyme A:cholesterol acyltransferase 1 inhibition in vitro measured in rabbit intestinal microsomesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAcyl-CoA:cholesterol acyltransferase(Rabbit)
TBA

Curated by ChEMBL
LigandPNGBDBM50054300(1-(2,6-Diisopropyl-phenyl)-3-(2-tridecyl-2,3-dihyd...)
Affinity DataIC50: 9nMAssay Description:Acyl coenzyme A:cholesterol acyltransferase 1 inhibition in vitro measured in rabbit intestinal microsomesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAcyl-CoA:cholesterol acyltransferase(Rabbit)
TBA

Curated by ChEMBL
LigandPNGBDBM50067769(1-Benzyl-1-[4-(4-fluoro-phenoxy)-benzyl]-3-(6-meth...)
Affinity DataIC50: 9.10nMAssay Description:In vitro inhibition of acyl coenzyme A:cholesterol acyltransferase (ACAT) from rabbit intestinal microsomesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAcyl-CoA:cholesterol acyltransferase(Rabbit)
TBA

Curated by ChEMBL
LigandPNGBDBM50039402(Tetradecyloxycarbonyl-carbamic acid 2,6-diisopropy...)
Affinity DataIC50: 10nMAssay Description:In vitro Acyl coenzyme A:cholesterol acyltransferase inhibitory activity (IAI) was determined by measuring the incorporation of [1-14C]oleolyl-CoA in...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAcyl-CoA:cholesterol acyltransferase(Rabbit)
TBA

Curated by ChEMBL
LigandPNGBDBM50067756(1-Benzyl-1-[4-(4-bromo-phenoxy)-benzyl]-3-(6-methy...)
Affinity DataIC50: 10nMAssay Description:In vitro inhibition of acyl coenzyme A:cholesterol acyltransferase (ACAT) from rabbit intestinal microsomesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAcyl-CoA:cholesterol acyltransferase(Rabbit)
TBA

Curated by ChEMBL
LigandPNGBDBM50281483(1-(2,6-Diisopropyl-phenyl)-3-(4-octyl-phenyl)-urea...)
Affinity DataIC50: 11nMAssay Description:In vitro inhibition of intestinal Acyl coenzyme A:cholesterol acyltransferase in cholesterol-fed rabbits.More data for this Ligand-Target Pair
In DepthDetails Article

TargetAcyl-CoA:cholesterol acyltransferase(Rabbit)
TBA

Curated by ChEMBL
LigandPNGBDBM50281490(1-(2,6-Diisopropyl-phenyl)-3-(4-tridecyl-phenyl)-u...)
Affinity DataIC50: 11nMAssay Description:In vitro inhibition of intestinal Acyl coenzyme A:cholesterol acyltransferase in cholesterol-fed rabbits.More data for this Ligand-Target Pair
In DepthDetails Article

TargetAcyl-CoA:cholesterol acyltransferase(Rabbit)
TBA

Curated by ChEMBL
LigandPNGBDBM50289048(N-(2,6-Diisopropyl-phenyl)-malonamic acid dodecyl ...)
Affinity DataIC50: 11nMAssay Description:In vitro inhibitory activity against Acyl coenzyme A:cholesterol acyltransferase in intestinal microsomes isolated from cholesterol fed rabbits (IAI)...More data for this Ligand-Target Pair
In DepthDetails Article

TargetAcyl-CoA:cholesterol acyltransferase(Rabbit)
TBA

Curated by ChEMBL
LigandPNGBDBM50289042(N-(2,6-Diisopropyl-phenyl)-malonamic acid 1-methyl...)
Affinity DataIC50: 11nMAssay Description:In vitro inhibitory activity against Acyl coenzyme A:cholesterol acyltransferase in intestinal microsomes isolated from cholesterol fed rabbits (IAI)...More data for this Ligand-Target Pair
In DepthDetails Article

TargetAcyl-CoA:cholesterol acyltransferase(Rabbit)
TBA

Curated by ChEMBL
LigandPNGBDBM50284967(1-[1-(2,6-Dichloro-phenyl)-1H-benzoimidazol-2-yl]-...)
Affinity DataIC50: 11nMAssay Description:In vitro inhibitory activity towards acyl CoA cholesterol acyltransferase (ACAT) of cholesterol-fed rabbits by the displacement of [14C]oleolyl-CoAMore data for this Ligand-Target Pair
In DepthDetails Article

TargetAcyl-CoA:cholesterol acyltransferase(Rabbit)
TBA

Curated by ChEMBL
LigandPNGBDBM50045915(N-(2,6-Diisopropyl-phenyl)-3-oxo-3-(1-phenyl-cyclo...)
Affinity DataIC50: 11nMAssay Description:In vitro inhibition of Acyl coenzyme A:cholesterol acyltransferase in intestinal microsomes isolated from cholesterol-fed rabbitsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAcyl-CoA:cholesterol acyltransferase(Rabbit)
TBA

Curated by ChEMBL
LigandPNGBDBM50045911(3-Oxo-pentadecanoic acid (2,6-diisopropyl-phenyl)-...)
Affinity DataIC50: 11nMAssay Description:In vitro inhibition of Acyl coenzyme A:cholesterol acyltransferase in intestinal microsomes isolated from cholesterol-fed rabbitsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAcyl-CoA:cholesterol acyltransferase(Rabbit)
TBA

Curated by ChEMBL
LigandPNGBDBM50041733(1-(2,6-Diisopropyl-phenyl)-3-[1-(3-morpholin-4-ylm...)
Affinity DataIC50: 11nMAssay Description:Tested for in vitro inhibition against Acyl coenzyme A:cholesterol acyltransferase of intestinal microsomes in cholesterol-fed rabbitsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAcyl-CoA:cholesterol acyltransferase(Rabbit)
TBA

Curated by ChEMBL
LigandPNGBDBM50289039(N-(2,6-Diisopropyl-phenyl)-malonamic acid 1,1-dime...)
Affinity DataIC50: 12nMAssay Description:In vitro inhibitory activity against Acyl coenzyme A:cholesterol acyltransferase in intestinal microsomes isolated from cholesterol fed rabbits (IAI)...More data for this Ligand-Target Pair
In DepthDetails Article

TargetAcyl-CoA:cholesterol acyltransferase(Rabbit)
TBA

Curated by ChEMBL
LigandPNGBDBM50289050(N-(2,6-Diisopropyl-phenyl)-malonamic acid 1-methyl...)
Affinity DataIC50: 12nMAssay Description:In vitro inhibitory activity against Acyl coenzyme A:cholesterol acyltransferase in intestinal microsomes isolated from cholesterol fed rabbits (IAI)...More data for this Ligand-Target Pair
In DepthDetails Article

TargetAcyl-CoA:cholesterol acyltransferase(Rabbit)
TBA

Curated by ChEMBL
LigandPNGBDBM50054288(1-(2,6-Diisopropyl-phenyl)-3-(2-tetradecyl-2,3-dih...)
Affinity DataIC50: 12nMAssay Description:Acyl coenzyme A:cholesterol acyltransferase 1 inhibition in vitro measured in rabbit intestinal microsomesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAcyl-CoA:cholesterol acyltransferase(Rabbit)
TBA

Curated by ChEMBL
LigandPNGBDBM50054279(1-(2,6-Diisopropyl-phenyl)-3-(2-dodecyl-2,3-dihydr...)
Affinity DataIC50: 12nMAssay Description:Acyl coenzyme A:cholesterol acyltransferase 1 inhibition in vitro measured in rabbit intestinal microsomesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAcyl-CoA:cholesterol acyltransferase(Rabbit)
TBA

Curated by ChEMBL
LigandPNGBDBM50067746(3-(4-Chloro-6-methyl-2-methylsulfanyl-pyridin-3-yl...)
Affinity DataIC50: 12nMAssay Description:In vitro inhibition of acyl coenzyme A:cholesterol acyltransferase (ACAT) from rabbit intestinal microsomesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAcyl-CoA:cholesterol acyltransferase(Rabbit)
TBA

Curated by ChEMBL
LigandPNGBDBM50454946(CHEMBL79602)
Affinity DataIC50: 12nMAssay Description:In vitro inhibitory activity against Acyl coenzyme A:cholesterol acyltransferase (ACAT) in rabbit intestinal microsomesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAcyl-CoA:cholesterol acyltransferase(Rabbit)
TBA

Curated by ChEMBL
LigandPNGBDBM50047595(1-Butyl-3-{2-[3-(5-isopropyl-4-phenyl-imidazol-1-y...)
Affinity DataIC50: 12nMAssay Description:Tested for inhibition against Acyl coenzyme A:cholesterol acyltransferase derived from rabbit aorta homogenate (>, denotes no effect at the concentra...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAcyl-CoA:cholesterol acyltransferase(Rabbit)
TBA

Curated by ChEMBL
LigandPNGBDBM50042104(1-(2,6-Diisopropyl-phenyl)-3-(1-thiophen-2-yl-cycl...)
Affinity DataIC50: 12nMAssay Description:In vitro inhibition of Acyl coenzyme A:cholesterol acyltransferase using intestinal microsomes isolated from cholesterol fed rabbitsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAcyl-CoA:cholesterol acyltransferase(Rabbit)
TBA

Curated by ChEMBL
LigandPNGBDBM50281496(1-(4-Decyl-phenyl)-3-(2,6-diisopropyl-phenyl)-urea...)
Affinity DataIC50: 13nMAssay Description:In vitro inhibition of intestinal Acyl coenzyme A:cholesterol acyltransferase in cholesterol-fed rabbits.More data for this Ligand-Target Pair
In DepthDetails Article

TargetAcyl-CoA:cholesterol acyltransferase(Rabbit)
TBA

Curated by ChEMBL
LigandPNGBDBM50054281(1-(2,6-Diisopropyl-phenyl)-3-(3-tridecyl-isoxazol-...)
Affinity DataIC50: 13nMAssay Description:Acyl coenzyme A:cholesterol acyltransferase 1 inhibition in vitro measured in rabbit intestinal microsomesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAcyl-CoA:cholesterol acyltransferase(Rabbit)
TBA

Curated by ChEMBL
LigandPNGBDBM50041764(1-(2,6-Diisopropyl-phenyl)-3-[1-(3-methoxy-phenyl)...)
Affinity DataIC50: 13nMAssay Description:Tested for in vitro inhibition against Acyl coenzyme A:cholesterol acyltransferase of intestinal microsomes in cholesterol-fed rabbitsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAcyl-CoA:cholesterol acyltransferase(Rabbit)
TBA

Curated by ChEMBL
LigandPNGBDBM50050362(2,2-Dimethyl-dodecanoic acid (7-methoxy-4-oxo-chro...)
Affinity DataIC50: 13nMAssay Description:Inhibitory activity against Acyl coenzyme A:cholesterol acyltransferase 1 obtained from rabbit intestine microsomesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAcyl-CoA:cholesterol acyltransferase(Rabbit)
TBA

Curated by ChEMBL
LigandPNGBDBM50296994(N-(5-Methanesulfonylamino-4,6-dimethyl-1-octylindo...)
Affinity DataIC50: 13nMAssay Description:Inhibition of ACAT in Japanese White rabbit liver microsomesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAcyl-CoA:cholesterol acyltransferase(Rabbit)
TBA

Curated by ChEMBL
LigandPNGBDBM50065041(1-Benzyl-1-[3-(2H-pyrazol-3-yl)-benzyl]-3-(2,4,6-t...)
Affinity DataIC50: 14nMAssay Description:In vitro inhibitory activity towards ACAT by the displacement of [1-14C]oleolyl-CoA from the small intestine of cholesterol-fed rabbitsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAcyl-CoA:cholesterol acyltransferase(Rabbit)
TBA

Curated by ChEMBL
LigandPNGBDBM50054278(1-(2,6-Diisopropyl-phenyl)-3-(5-tridecyl-isoxazol-...)
Affinity DataIC50: 14nMAssay Description:Acyl coenzyme A:cholesterol acyltransferase 1 inhibition in vitro measured in rabbit intestinal microsomesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAcyl-CoA:cholesterol acyltransferase(Rabbit)
TBA

Curated by ChEMBL
LigandPNGBDBM50054284(1-(2-Decyl-2,3-dihydro-1H-tetrazol-5-yl)-3-(2,6-di...)
Affinity DataIC50: 14nMAssay Description:Acyl coenzyme A:cholesterol acyltransferase 1 inhibition in vitro measured in rabbit intestinal microsomesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAcyl-CoA:cholesterol acyltransferase(Rabbit)
TBA

Curated by ChEMBL
LigandPNGBDBM50054302(1-(2,6-Diisopropyl-phenyl)-3-(2-dodecyl-2,3-dihydr...)
Affinity DataIC50: 14nMAssay Description:Acyl coenzyme A:cholesterol acyltransferase 1 inhibition in vitro measured in rabbit intestinal microsomesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAcyl-CoA:cholesterol acyltransferase(Rabbit)
TBA

Curated by ChEMBL
LigandPNGBDBM50065041(1-Benzyl-1-[3-(2H-pyrazol-3-yl)-benzyl]-3-(2,4,6-t...)
Affinity DataIC50: 14nMAssay Description:In vitro inhibition of acyl coenzyme A:cholesterol acyltransferase (ACAT) from rabbit intestinal microsomesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAcyl-CoA:cholesterol acyltransferase(Rabbit)
TBA

Curated by ChEMBL
LigandPNGBDBM50067753(1-Cycloheptyl-3-(2,4-dichloro-6-methyl-pyridin-3-y...)
Affinity DataIC50: 14nMAssay Description:In vitro inhibition of acyl coenzyme A:cholesterol acyltransferase (ACAT) from rabbit intestinal microsomesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAcyl-CoA:cholesterol acyltransferase(Rabbit)
TBA

Curated by ChEMBL
LigandPNGBDBM50065041(1-Benzyl-1-[3-(2H-pyrazol-3-yl)-benzyl]-3-(2,4,6-t...)
Affinity DataIC50: 14nMAssay Description:In vitro inhibitory activity against Acyl coenzyme A:cholesterol acyltransferase (ACAT) in rabbit intestinal microsomesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAcyl-CoA:cholesterol acyltransferase(Rabbit)
TBA

Curated by ChEMBL
LigandPNGBDBM50281494(1-(2,6-Diisopropyl-phenyl)-3-(4-dodecyl-phenyl)-ur...)
Affinity DataIC50: 15nMAssay Description:In vitro inhibition of intestinal Acyl coenzyme A:cholesterol acyltransferase in cholesterol-fed rabbits.More data for this Ligand-Target Pair
In DepthDetails Article

TargetAcyl-CoA:cholesterol acyltransferase(Rabbit)
TBA

Curated by ChEMBL
LigandPNGBDBM50079715(Tetradecanethioic acid (2,6-diisopropyl-phenyl)-am...)
Affinity DataIC50: 15nMAssay Description:Compound was tested for inhibitory activity against ACAT from rabbit liverMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAcyl-CoA:cholesterol acyltransferase(Rabbit)
TBA

Curated by ChEMBL
LigandPNGBDBM50289036(N-(2,6-Diisopropyl-phenyl)-malonamic acid 1,1-dime...)
Affinity DataIC50: 15nMAssay Description:In vitro inhibitory activity against Acyl coenzyme A:cholesterol acyltransferase in intestinal microsomes isolated from cholesterol fed rabbits (IAI)...More data for this Ligand-Target Pair
In DepthDetails Article

Displayed 1 to 50 (of 1059 total ) | Next | Last >>
Jump to: