Compile Data Set for Download or QSAR
Report error Found 125 of ic50 data for polymerid = 49001107
TargetSentrin-specific protease 2(Human)
Stanford University

LigandPNGBDBM81515(VEA-499)
Affinity DataIC50: 250nMpH: 8.0 T: 2°CAssay Description:The fluorogenic substrate library screen was performed with hSENP1 in low salt tris buffer at final concentration of 2uM. Fluorophore release (AFC) ...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails Article
PubMed
TargetSentrin-specific protease 2(Human)
Stanford University

LigandPNGBDBM50565392(CHEMBL4791433)
Affinity DataIC50: 560nMAssay Description:Inhibition of recombinant human SNEP2 (365 to 589 residues) expressed in Escherichia coli (DE3) cells using RanGAP-SUMO2 substrate preincubated for 1...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetSentrin-specific protease 2(Human)
Stanford University

LigandPNGBDBM50565398(CHEMBL4776158)
Affinity DataIC50: 690nMAssay Description:Inhibition of recombinant human SNEP2 (365 to 589 residues) expressed in Escherichia coli (DE3) cells using RanGAP-SUMO2 substrate preincubated for 1...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSentrin-specific protease 2(Human)
Stanford University

LigandPNGBDBM81516(VEA-500)
Affinity DataIC50: 860nMpH: 8.0 T: 2°CAssay Description:The fluorogenic substrate library screen was performed with hSENP1 in low salt tris buffer at final concentration of 2uM. Fluorophore release (AFC) ...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails Article
PubMed
TargetSentrin-specific protease 2(Human)
Stanford University

LigandPNGBDBM103826(SPI-01 | US9791447, Compound SPI-01 | US11041859, ...)
Affinity DataIC50: 1.10E+3nMpH: 7.4Assay Description:Assays were performedby incubating SENPs with various concentrations of the inhibitor (0−60 μM) at RT for 10 min in assay buffer (50 mM Tr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetSentrin-specific protease 2(Human)
Stanford University

LigandPNGBDBM50565346(CHEMBL4781794)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of human His-tagged SENP2 (364 to 589 residues) expressed in Escherichia coli (DE3) cells using DUB-Glo as substrate preincubated for 10 m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetSentrin-specific protease 2(Human)
Stanford University

LigandPNGBDBM50565391(CHEMBL4792569)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of recombinant human SNEP2 (365 to 589 residues) expressed in Escherichia coli (DE3) cells using RanGAP-SUMO2 substrate preincubated for 1...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetSentrin-specific protease 2(Human)
Stanford University

LigandPNGBDBM50565393(CHEMBL4780770)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of recombinant human SNEP2 (365 to 589 residues) expressed in Escherichia coli (DE3) cells using RanGAP-SUMO2 substrate preincubated for 1...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetSentrin-specific protease 2(Human)
Stanford University

LigandPNGBDBM103826(SPI-01 | US9791447, Compound SPI-01 | US11041859, ...)
Affinity DataIC50: 1.42E+3nMpH: 7.4Assay Description:Assays were performedby incubating SENPs with various concentrations of the inhibitor (0−60 μM) at RT for 10 min in assay buffer (50 mM Tr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetSentrin-specific protease 2(Human)
Stanford University

LigandPNGBDBM103829(SPI-04 | US9791447, Compound SPI-04 | US11041859, ...)
Affinity DataIC50: 1.60E+3nMpH: 7.4Assay Description:Assays were performedby incubating SENPs with various concentrations of the inhibitor (0−60 μM) at RT for 10 min in assay buffer (50 mM Tr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetSentrin-specific protease 2(Human)
Stanford University

LigandPNGBDBM50565390(CHEMBL4780586)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of recombinant human SNEP2 (365 to 589 residues) expressed in Escherichia coli (DE3) cells using RanGAP-SUMO2 substrate preincubated for 1...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetSentrin-specific protease 2(Human)
Stanford University

LigandPNGBDBM103827(SPI-02 | US9791447, Compound SPI-02 | US11041859, ...)
Affinity DataIC50: 2.00E+3nMAssay Description:The binding of SPI-01 to the enzyme-substrate complex was investigated. CSP analysis was carried out on the 40 kDa complex of 15N-labeled full length...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetSentrin-specific protease 2(Human)
Stanford University

LigandPNGBDBM103827(SPI-02 | US9791447, Compound SPI-02 | US11041859, ...)
Affinity DataIC50: 2.00E+3nMAssay Description:The inhibitors confer the non-competitive inhibitory mechanism, as shown by nuclear magnetic resonance (NMR) and quantitative enzyme kinetic analysis...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetSentrin-specific protease 2(Human)
Stanford University

LigandPNGBDBM103827(SPI-02 | US9791447, Compound SPI-02 | US11041859, ...)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of His-tagged human SENP2 (364 to 589 residues) expressed in Escherichia coli (DE3) using YFP-SUMO-ECFP as substrate incubated for 15 mins...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetSentrin-specific protease 2(Human)
Stanford University

LigandPNGBDBM103827(SPI-02 | US9791447, Compound SPI-02 | US11041859, ...)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of SENP2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetSentrin-specific protease 2(Human)
Stanford University

LigandPNGBDBM103829(SPI-04 | US9791447, Compound SPI-04 | US11041859, ...)
Affinity DataIC50: 2.15E+3nMpH: 7.4Assay Description:Assays were performedby incubating SENPs with various concentrations of the inhibitor (0−60 μM) at RT for 10 min in assay buffer (50 mM Tr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetSentrin-specific protease 2(Human)
Stanford University

LigandPNGBDBM50565350(CHEMBL4796113)
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of recombinant human SNEP2 (365 to 589 residues) expressed in Escherichia coli (DE3) cells using RanGAP-SUMO2 substrate preincubated for 1...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetSentrin-specific protease 2(Human)
Stanford University

LigandPNGBDBM103829(SPI-04 | US9791447, Compound SPI-04 | US11041859, ...)
Affinity DataIC50: 2.30E+3nMAssay Description:The binding of SPI-01 to the enzyme-substrate complex was investigated. CSP analysis was carried out on the 40 kDa complex of 15N-labeled full length...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetSentrin-specific protease 2(Human)
Stanford University

LigandPNGBDBM50565382(CHEMBL4778045)
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of recombinant human SNEP2 (365 to 589 residues) expressed in Escherichia coli (DE3) cells using RanGAP-SUMO2 substrate preincubated for 1...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetSentrin-specific protease 2(Human)
Stanford University

LigandPNGBDBM103829(SPI-04 | US9791447, Compound SPI-04 | US11041859, ...)
Affinity DataIC50: 2.30E+3nMAssay Description:The inhibitors confer the non-competitive inhibitory mechanism, as shown by nuclear magnetic resonance (NMR) and quantitative enzyme kinetic analysis...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetSentrin-specific protease 2(Human)
Stanford University

LigandPNGBDBM50421693(CHEMBL5269877)
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of SENP2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetSentrin-specific protease 2(Human)
Stanford University

LigandPNGBDBM348885(NSC8676 | US9791447, Compound SPI-03)
Affinity DataIC50: 2.40E+3nMAssay Description:The binding of SPI-01 to the enzyme-substrate complex was investigated. CSP analysis was carried out on the 40 kDa complex of 15N-labeled full length...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetSentrin-specific protease 2(Human)
Stanford University

LigandPNGBDBM50565396(CHEMBL4783695)
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of recombinant human SNEP2 (365 to 589 residues) expressed in Escherichia coli (DE3) cells using RanGAP-SUMO2 substrate preincubated for 1...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetSentrin-specific protease 2(Human)
Stanford University

LigandPNGBDBM103828(SPI-03 | US11041859, Code SPI-03)
Affinity DataIC50: 2.40E+3nMAssay Description:The inhibitors confer the non-competitive inhibitory mechanism, as shown by nuclear magnetic resonance (NMR) and quantitative enzyme kinetic analysis...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetSentrin-specific protease 2(Human)
Stanford University

LigandPNGBDBM103828(SPI-03 | US11041859, Code SPI-03)
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of SENP2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetSentrin-specific protease 2(Human)
Stanford University

LigandPNGBDBM103835(SPI-10 | US9791447, Compound SPI-10 | US11041859, ...)
Affinity DataIC50: 2.50E+3nMAssay Description:The binding of SPI-01 to the enzyme-substrate complex was investigated. CSP analysis was carried out on the 40 kDa complex of 15N-labeled full length...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetSentrin-specific protease 2(Human)
Stanford University

LigandPNGBDBM50565378(CHEMBL4793952)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of recombinant human SNEP2 (365 to 589 residues) expressed in Escherichia coli (DE3) cells using RanGAP-SUMO2 substrate preincubated for 1...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetSentrin-specific protease 2(Human)
Stanford University

LigandPNGBDBM103835(SPI-10 | US9791447, Compound SPI-10 | US11041859, ...)
Affinity DataIC50: 2.50E+3nMAssay Description:The inhibitors confer the non-competitive inhibitory mechanism, as shown by nuclear magnetic resonance (NMR) and quantitative enzyme kinetic analysis...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetSentrin-specific protease 2(Human)
Stanford University

LigandPNGBDBM50421692(CHEMBL5287963)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of SENP2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetSentrin-specific protease 2(Human)
Stanford University

LigandPNGBDBM103827(SPI-02 | US9791447, Compound SPI-02 | US11041859, ...)
Affinity DataIC50: 2.70E+3nMpH: 7.4Assay Description:Assays were performedby incubating SENPs with various concentrations of the inhibitor (0−60 μM) at RT for 10 min in assay buffer (50 mM Tr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetSentrin-specific protease 2(Human)
Stanford University

LigandPNGBDBM50164846(CHEMBL3799152)
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibition of human recombinant His-tagged SENP2 (363 to 589 residues) expressed in Escherichia coli BL21 (DE3) using RanGAP-SUMO as substrate incuba...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSentrin-specific protease 2(Human)
Stanford University

LigandPNGBDBM50164846(CHEMBL3799152)
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibition of human recombinant His-tagged SENP2 (363 to 589 residues) expressed in Escherichia coli BL21 (DE3) using RanGAP-SUMO as substrate incuba...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSentrin-specific protease 2(Human)
Stanford University

LigandPNGBDBM103826(SPI-01 | US9791447, Compound SPI-01 | US11041859, ...)
Affinity DataIC50: 2.90E+3nMAssay Description:The binding of SPI-01 to the enzyme-substrate complex was investigated. CSP analysis was carried out on the 40 kDa complex of 15N-labeled full length...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetSentrin-specific protease 2(Human)
Stanford University

LigandPNGBDBM103826(SPI-01 | US9791447, Compound SPI-01 | US11041859, ...)
Affinity DataIC50: 2.90E+3nMAssay Description:The inhibitors confer the non-competitive inhibitory mechanism, as shown by nuclear magnetic resonance (NMR) and quantitative enzyme kinetic analysis...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetSentrin-specific protease 2(Human)
Stanford University

LigandPNGBDBM103826(SPI-01 | US9791447, Compound SPI-01 | US11041859, ...)
Affinity DataIC50: 2.90E+3nMAssay Description:Inhibition of SENP2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetSentrin-specific protease 2(Human)
Stanford University

LigandPNGBDBM103828(SPI-03 | US11041859, Code SPI-03)
Affinity DataIC50: 3.00E+3nMpH: 7.4Assay Description:Assays were performedby incubating SENPs with various concentrations of the inhibitor (0−60 μM) at RT for 10 min in assay buffer (50 mM Tr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetSentrin-specific protease 2(Human)
Stanford University

LigandPNGBDBM103827(SPI-02 | US9791447, Compound SPI-02 | US11041859, ...)
Affinity DataIC50: 3.42E+3nMpH: 7.4Assay Description:Assays were performedby incubating SENPs with various concentrations of the inhibitor (0−60 μM) at RT for 10 min in assay buffer (50 mM Tr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetSentrin-specific protease 2(Human)
Stanford University

LigandPNGBDBM50565352(CHEMBL4791044)
Affinity DataIC50: 3.50E+3nMAssay Description:Inhibition of recombinant human SNEP2 (365 to 589 residues) expressed in Escherichia coli (DE3) cells using RanGAP-SUMO2 substrate preincubated for 1...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetSentrin-specific protease 2(Human)
Stanford University

LigandPNGBDBM50565397(CHEMBL4796293)
Affinity DataIC50: 3.50E+3nMAssay Description:Inhibition of recombinant human SNEP2 (365 to 589 residues) expressed in Escherichia coli (DE3) cells using RanGAP-SUMO2 substrate preincubated for 1...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetSentrin-specific protease 2(Human)
Stanford University

LigandPNGBDBM103831(SPI-06)
Affinity DataIC50: 3.62E+3nMpH: 7.4Assay Description:Assays were performedby incubating SENPs with various concentrations of the inhibitor (0−60 μM) at RT for 10 min in assay buffer (50 mM Tr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetSentrin-specific protease 2(Human)
Stanford University

LigandPNGBDBM81511(VEA-260)
Affinity DataIC50: 3.70E+3nMpH: 8.0 T: 2°CAssay Description:The fluorogenic substrate library screen was performed with hSENP1 in low salt tris buffer at final concentration of 2uM. Fluorophore release (AFC) ...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails Article
PubMed
TargetSentrin-specific protease 2(Human)
Stanford University

LigandPNGBDBM348888(NSC70551 | US9791447, Compound SPI-06 | US11041859...)
Affinity DataIC50: 3.70E+3nMAssay Description:The binding of SPI-01 to the enzyme-substrate complex was investigated. CSP analysis was carried out on the 40 kDa complex of 15N-labeled full length...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetSentrin-specific protease 2(Human)
Stanford University

LigandPNGBDBM348888(NSC70551 | US9791447, Compound SPI-06 | US11041859...)
Affinity DataIC50: 3.70E+3nMAssay Description:The inhibitors confer the non-competitive inhibitory mechanism, as shown by nuclear magnetic resonance (NMR) and quantitative enzyme kinetic analysis...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetSentrin-specific protease 2(Human)
Stanford University

LigandPNGBDBM50591764(CHEMBL5207368)
Affinity DataIC50: 3.70E+3nMAssay Description:Inhibition of human SENP2 using QTGG-AFC as substrate by fluorescence based analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetSentrin-specific protease 2(Human)
Stanford University

LigandPNGBDBM50591766(CHEMBL5188918)
Affinity DataIC50: 3.70E+3nMAssay Description:Inhibition of recombinant human SENP2 in presence of DTT by FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetSentrin-specific protease 2(Human)
Stanford University

LigandPNGBDBM103831(SPI-06)
Affinity DataIC50: 3.70E+3nMAssay Description:Inhibition of SENP2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetSentrin-specific protease 2(Human)
Stanford University

LigandPNGBDBM50591766(CHEMBL5188918)
Affinity DataIC50: 3.70E+3nMAssay Description:Inhibition of SENP2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetSentrin-specific protease 2(Human)
Stanford University

LigandPNGBDBM50565389(CHEMBL4789655)
Affinity DataIC50: 3.90E+3nMAssay Description:Inhibition of recombinant human SNEP2 (365 to 589 residues) expressed in Escherichia coli (DE3) cells using RanGAP-SUMO2 substrate preincubated for 1...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetSentrin-specific protease 2(Human)
Stanford University

LigandPNGBDBM103833(SPI-08 | US9791447, Compound SPI-08 | US11041859, ...)
Affinity DataIC50: 4.10E+3nMpH: 7.4Assay Description:Assays were performedby incubating SENPs with various concentrations of the inhibitor (0−60 μM) at RT for 10 min in assay buffer (50 mM Tr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetSentrin-specific protease 2(Human)
Stanford University

LigandPNGBDBM103830(SPI-05 | US9791447, Compound SPI-05 | US11041859, ...)
Affinity DataIC50: 4.60E+3nMpH: 7.4Assay Description:Assays were performedby incubating SENPs with various concentrations of the inhibitor (0−60 μM) at RT for 10 min in assay buffer (50 mM Tr...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
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