Compile Data Set for Download or QSAR
Report error Found 373 of ic50 data for polymerid = 49000701,49000702,50001123
TargetLeukotriene B4 receptor 1(Human)
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50317628(4-{2-(2-Carboxy-ethyl)-3-[6-(3,5-di-pyridin-4-yl-p...)
Affinity DataIC50: 0.0700nMAssay Description:Antagonist activity at BLT1 receptor expressed in human HL60 cells assessed as inhibition of LTB4-stimulated calcium flux after 30 minsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLeukotriene B4 receptor 1(Human)
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50284125(SC-52073 | 7-[3-(4-Isopropylcarbamoyl-3-methoxy-2-...)
Affinity DataIC50: 0.100nMAssay Description:Inhibitory activity against leukotriene B4 receptorMore data for this Ligand-Target Pair
In DepthDetails Article

TargetLeukotriene B4 receptor 1(Human)
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50213060(CHEMBL355401 | SC-50135)
Affinity DataIC50: 0.100nMAssay Description:Inhibitory activity against leukotriene B4 receptorMore data for this Ligand-Target Pair
In DepthDetails Article

TargetLeukotriene B4 receptor 1(Human)
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50284122(7-[3-(4-Dimethylcarbamoyl-3-methoxy-2-propyl-pheno...)
Affinity DataIC50: 0.150nMAssay Description:Inhibitory activity against leukotriene B4 receptorMore data for this Ligand-Target Pair
In DepthDetails Article

TargetLeukotriene B4 receptor 1(Human)
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50317631(4-{2-(2-Carboxy-ethyl)-3-[6-(3'-fluoro-5-pyridin-4...)
Affinity DataIC50: 0.180nMAssay Description:Antagonist activity at BLT1 receptor expressed in human HL60 cells assessed as inhibition of LTB4-stimulated calcium flux after 30 minsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLeukotriene B4 receptor 1(Human)
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50317632(4-{2-(2-Carboxy-ethyl)-3-[6-(3-pyridin-4-yl-5-thio...)
Affinity DataIC50: 0.200nMAssay Description:Antagonist activity at BLT1 receptor expressed in human HL60 cells assessed as inhibition of LTB4-stimulated calcium flux after 30 minsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLeukotriene B4 receptor 1(Human)
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50317625(4-{2-(2-Carboxyethyl)-3-[6-([1,1',3,1'']terphenyl-...)
Affinity DataIC50: 0.210nMAssay Description:Antagonist activity at BLT1 receptor expressed in human HL60 cells assessed as inhibition of LTB4-stimulated calcium flux after 30 minsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLeukotriene B4 receptor 1(Human)
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50317633(4-{3-[6-(3-Benzo[1,3]dioxol-5-yl-5-pyridin-4-yl-ph...)
Affinity DataIC50: 0.220nMAssay Description:Antagonist activity at BLT1 receptor expressed in human HL60 cells assessed as inhibition of LTB4-stimulated calcium flux after 30 minsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLeukotriene B4 receptor 1(Human)
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50317634(4-{2-(2-Carboxyethyl)-3-[6-(5-thiophen-3-ylbipheny...)
Affinity DataIC50: 0.360nMAssay Description:Antagonist activity at BLT1 receptor expressed in human HL60 cells assessed as inhibition of LTB4-stimulated calcium flux after 30 minsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLeukotriene B4 receptor 1(Human)
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50001609(CHEMBL328712 | 8-Benzyloxy-4-[(methyl-phenethyl-ca...)
Affinity DataIC50: 0.360nMAssay Description:Antagonistic activity against LTB4 receptor using guinea pig (GP) spleen cell membraneMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLeukotriene B4 receptor 1(Human)
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50317635(4-{3-[6-(3-Benzo[1,3]dioxol-5-yl-5-pyrimidin-5-yl-...)
Affinity DataIC50: 0.380nMAssay Description:Antagonist activity at BLT1 receptor expressed in human HL60 cells assessed as inhibition of LTB4-stimulated calcium flux after 30 minsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLeukotriene B4 receptor 1(Human)
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50317636(4-{2-(2-Carboxy-ethyl)-3-[6-(3-pyrimidin-5-yl-5-th...)
Affinity DataIC50: 0.390nMAssay Description:Antagonist activity at BLT1 receptor expressed in human HL60 cells assessed as inhibition of LTB4-stimulated calcium flux after 30 minsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLeukotriene B4 receptor 1(Human)
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50317626(4-{3-[6-(3-5-Benzo[1,3]dioxolyl-5-thiophen-3-ylphe...)
Affinity DataIC50: 0.440nMAssay Description:Antagonist activity at BLT1 receptor expressed in human HL60 cells assessed as inhibition of LTB4-stimulated calcium flux after 30 minsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLeukotriene B4 receptor 1(Human)
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50317624(4-(2-(2-carboxyethyl)-3-(6-(4,6-diphenylpyridin-2-...)
Affinity DataIC50: 0.480nMAssay Description:Antagonist activity at BLT1 receptor expressed in human HL60 cells assessed as inhibition of LTB4-stimulated calcium flux after 30 minsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLeukotriene B4 receptor 1(Human)
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50317637(4-(2-(2-Carboxy-ethyl)-3-{6-[3-(2-chloro-pyridin-4...)
Affinity DataIC50: 0.570nMAssay Description:Antagonist activity at BLT1 receptor expressed in human HL60 cells assessed as inhibition of LTB4-stimulated calcium flux after 30 minsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLeukotriene B4 receptor 1(Human)
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50317638(4-{2-(2-Carboxy-ethyl)-3-[6-(3,5-di-thiophen-3-yl-...)
Affinity DataIC50: 0.580nMAssay Description:Antagonist activity at BLT1 receptor expressed in human HL60 cells assessed as inhibition of LTB4-stimulated calcium flux after 30 minsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLeukotriene B4 receptor 1(Human)
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50317639(4-[3-[6-(5-Benzo[1,3]dioxol-5-yl-biphenyl-3-yloxy)...)
Affinity DataIC50: 0.580nMAssay Description:Antagonist activity at BLT1 receptor expressed in human HL60 cells assessed as inhibition of LTB4-stimulated calcium flux after 30 minsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLeukotriene B4 receptor 1(Human)
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50317630(4-(3-(6-(5-(benzo[d][1,3]dioxol-5-yl)-2'-fluorobip...)
Affinity DataIC50: 0.610nMAssay Description:Antagonist activity at BLT1 receptor expressed in human HL60 cells assessed as inhibition of LTB4-stimulated calcium flux after 30 minsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLeukotriene B4 receptor 1(Human)
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50001609(CHEMBL328712 | 8-Benzyloxy-4-[(methyl-phenethyl-ca...)
Affinity DataIC50: 0.800nMAssay Description:Concentration inhibiting 1 nM LTB4-induced aggregation in GP polymorphonuclear (PMN) leukocytes.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLeukotriene B4 receptor 1(Human)
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50284123(SC-50073 | 7-[3-(3-Methoxy-4-methylcarbamoyl-2-pro...)
Affinity DataIC50: 0.850nMAssay Description:Inhibitory activity against leukotriene B4 receptorMore data for this Ligand-Target Pair
In DepthDetails Article

TargetLeukotriene B4 receptor 1(Human)
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50001610(CHEMBL14823 | CGS 24115 | 7-[3-(4-Acetyl-3-methoxy...)
Affinity DataIC50: 1nMAssay Description:Inhibitory activity against leukotriene B4 receptorMore data for this Ligand-Target Pair
In DepthDetails Article

TargetLeukotriene B4 receptor 1(Human)
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50001668(CHEMBL137759 | 6-(4-Benzo[1,3]dioxol-5-yl-6-phenyl...)
Affinity DataIC50: 1nMAssay Description:Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLeukotriene B4 receptor 1(Human)
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50317623(4-(3-(6-(5-(benzo[d][1,3]dioxol-5-yl)-3'-fluorobip...)
Affinity DataIC50: 1.19nMAssay Description:Antagonist activity at BLT1 receptor expressed in human HL60 cells assessed as inhibition of LTB4-stimulated calcium flux after 30 minsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLeukotriene B4 receptor 1(Human)
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50037390(3-{(S)-2-(2-Carboxy-ethyl)-7-[3-(2-cyclopropylmeth...)
Affinity DataIC50: 1.30nMAssay Description:Compound was tested for inhibitory activity against human neutrophil LTB4 receptor bindingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLeukotriene B4 receptor 1(Human)
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50052017(SC-51146 | 3-{7-[3-(2-Cyclopropylmethyl-3-methoxy-...)
Affinity DataIC50: 1.5nMAssay Description:Compound was tested for inhibitory activity against human neutrophil LTB4 receptor bindingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLeukotriene B4 receptor 1(Human)
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50013889(5,12-Dihete | CHEMBL65061 | LTB4 | 5,12-Hete | (S-...)
Affinity DataIC50: 1.90nMAssay Description:Inhibition of specific binding of [3H]LTB4 to Leukotriene B4 receptor in human neutrophilsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetLeukotriene B4 receptor 1(Human)
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50001611((Z)-3-{3-(2-Carboxy-ethyl)-4-[6-(4-methoxy-phenyl)...)
Affinity DataIC50: 1.90nMAssay Description:Inhibition of binding of [3H]LTB4 to receptor on nonradioactive LTB4More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLeukotriene B4 receptor 1(Human)
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50013889(5,12-Dihete | CHEMBL65061 | LTB4 | 5,12-Hete | (S-...)
Affinity DataIC50: 1.90nMAssay Description:In vitro antagonistic activity towards LTB4 receptor was evaluated by inhibition of binding of [3H]LTB4 to human neutrophilsMore data for this Ligand-Target Pair
In DepthDetails Article
PDB3D3D Structure (crystal)
TargetLeukotriene B4 receptor 1(Human)
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50001611((Z)-3-{3-(2-Carboxy-ethyl)-4-[6-(4-methoxy-phenyl)...)
Affinity DataIC50: 2nMAssay Description:Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLeukotriene B4 receptor 1(Human)
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50001611((Z)-3-{3-(2-Carboxy-ethyl)-4-[6-(4-methoxy-phenyl)...)
Affinity DataIC50: 2nMAssay Description:Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLeukotriene B4 receptor 1(Human)
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50001667(CHEMBL136991 | 6-[4-(4-Amino-phenyl)-6-phenyl-pyri...)
Affinity DataIC50: 2nMAssay Description:Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLeukotriene B4 receptor 1(Human)
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50001657(CHEMBL137074 | 6-[4-Benzo[1,3]dioxol-5-yl-6-(2-chl...)
Affinity DataIC50: 2nMAssay Description:Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLeukotriene B4 receptor 1(Human)
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50001637(CHEMBL137336 | 6-[4-(3-Methoxy-phenyl)-6-phenyl-py...)
Affinity DataIC50: 2nMAssay Description:Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLeukotriene B4 receptor 1(Human)
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50033746(SC-48928 | 7-[3-(4-Carbamoyl-3-methoxy-2-propyl-ph...)
Affinity DataIC50: 2.40nMAssay Description:Inhibitory activity against leukotriene B4 receptorMore data for this Ligand-Target Pair
In DepthDetails Article

TargetLeukotriene B4 receptor 1(Human)
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50280292(7-[3-(2-Ethyl-5-hydroxy-4-methoxy-phenoxy)-propoxy...)
Affinity DataIC50: 2.90nMAssay Description:In vitro binding affinity using [3H]LTB4 radioligand binding to leukotriene B4 receptor in human neutrophil binding assayMore data for this Ligand-Target Pair
In DepthDetails Article

TargetLeukotriene B4 receptor 1(Human)
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50001658(CHEMBL137504 | 6-(4,6-Diphenyl-pyridin-2-yloxy)-he...)
Affinity DataIC50: 3nMAssay Description:Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLeukotriene B4 receptor 1(Human)
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50033743(7-[3-(2-Cyclopropylmethyl-3-methoxy-4-thiazol-4-yl...)
Affinity DataIC50: 3.20nMAssay Description:Binding affinity towards Leukotriene B4 (LTB4) Receptor. Experiment conducted in the absence of NDGA.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLeukotriene B4 receptor 1(Human)
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50317641(4-(3-(6-(5-(benzo[d][1,3]dioxol-5-yl)-4'-methoxybi...)
Affinity DataIC50: 3.27nMAssay Description:Antagonist activity at BLT1 receptor expressed in human HL60 cells assessed as inhibition of LTB4-stimulated calcium flux after 30 minsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLeukotriene B4 receptor 1(Human)
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50001611((Z)-3-{3-(2-Carboxy-ethyl)-4-[6-(4-methoxy-phenyl)...)
Affinity DataIC50: 3.5nMAssay Description:Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLeukotriene B4 receptor 1(Human)
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50001611((Z)-3-{3-(2-Carboxy-ethyl)-4-[6-(4-methoxy-phenyl)...)
Affinity DataIC50: 3.5nMAssay Description:Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLeukotriene B4 receptor 1(Human)
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50029482(6-[3-(4-Acetyl-2-ethyl-5-hydroxy-phenoxy)-propoxy]...)
Affinity DataIC50: 4nMAssay Description:Compound was tested for inhibitory activity against human neutrophil LTB4 receptor bindingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLeukotriene B4 receptor 1(Human)
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50052021(4-[5-(4-Carbamimidoyl-phenoxy)-pentyloxy]-N,N-diis...)
Affinity DataIC50: 4nMAssay Description:Compound was tested for inhibitory activity against Leukotriene B4 receptor bindingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLeukotriene B4 receptor 1(Human)
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50280884(3-{3-[3-(4-acetyl-2-ethyl-5-olatophenoxy)propoxy]-...)
Affinity DataIC50: 4nMAssay Description:In vitro antagonistic activity towards LTB4 receptor was evaluated by inhibition of binding of [3H]LTB4 to human neutrophilsMore data for this Ligand-Target Pair
In DepthDetails Article

TargetLeukotriene B4 receptor 1(Human)
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50001641(CHEMBL137581 | 6-(4,6-Diphenyl-pyridin-2-yloxy)-2-...)
Affinity DataIC50: 4nMAssay Description:Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLeukotriene B4 receptor 1(Human)
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50001645(CHEMBL344230 | 6-[6-(2-Fluoro-phenyl)-4-phenyl-pyr...)
Affinity DataIC50: 4nMAssay Description:Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLeukotriene B4 receptor 1(Human)
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50001661(CHEMBL137531 | 6-[4-(4-Methoxy-phenyl)-6-phenyl-py...)
Affinity DataIC50: 4nMAssay Description:Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLeukotriene B4 receptor 1(Human)
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50280291(7-[3-(4-Ethoxy-2-ethyl-5-hydroxy-phenoxy)-propoxy]...)
Affinity DataIC50: 4.20nMAssay Description:In vitro binding affinity using [3H]LTB4 radioligand binding to leukotriene B4 receptor in human neutrophil binding assayMore data for this Ligand-Target Pair
In DepthDetails Article

TargetLeukotriene B4 receptor 1(Human)
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50001647(CHEMBL137341 | 6-(4-Benzo[1,3]dioxol-5-yl-6-phenyl...)
Affinity DataIC50: 4.20nMAssay Description:Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLeukotriene B4 receptor 1(Human)
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50039472(7-{3-[2-Ethyl-5-hydroxy-4-(1H-pyrazol-3-yl)-phenox...)
Affinity DataIC50: 4.5nMAssay Description:Inhibition of [3H]Leukotriene B4 binding to human PMNMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLeukotriene B4 receptor 1(Human)
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50001609(CHEMBL328712 | 8-Benzyloxy-4-[(methyl-phenethyl-ca...)
Affinity DataIC50: 4.70nMAssay Description:Concentration inhibiting the binding of [3H]LTB4 to human whole cell neutrophilsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
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