Compile Data Set for Download or QSAR
Report error Found 440 of ic50 data for polymerid = 49000386,50000212,50006976
TargetMuscarinic acetylcholine receptor M5(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50296345(Tiotropium Bromide | (1R,2R,4S,5R,7S)-7-(2-hydroxy...)
Affinity DataIC50: 0.100nMAssay Description:Displacement of [3H]NMS from human muscarinic M5 receptor expressed in CHO-K1 cells after 16 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMuscarinic acetylcholine receptor M5(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50296331((3R)-3-{[Hydroxy(di-2-thienyl)acetyl]oxy}-1-(3-phe...)
Affinity DataIC50: 0.158nMAssay Description:Displacement of [3H]NMS from human muscarinic M5 receptor expressed in CHO-K1 cells after 16 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMuscarinic acetylcholine receptor M5(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50417445(AHR-504 | CUVPOSA | GLYCOPYRROLATE)
Affinity DataIC50: 0.200nMAssay Description:Displacement of [3H]NMS from human muscarinic M5 receptor expressed in CHO-K1 cells after 16 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMuscarinic acetylcholine receptor M5(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50176065(CHEMBL76897 | CHEMBL168067 | 4-Diphenylacetoxy-1,1...)
Affinity DataIC50: 0.320nMAssay Description:Displacement of [3H]4-DAMP from human recombinant muscarinic M5 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMuscarinic acetylcholine receptor M5(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50176065(CHEMBL76897 | CHEMBL168067 | 4-Diphenylacetoxy-1,1...)
Affinity DataIC50: 0.320nMAssay Description:Displacement of [3H]4-DAMP from human recombinant M5 receptor expressed in CHO cells measured after 60 mins by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMuscarinic acetylcholine receptor M5(Rat)
University of Arkansas For Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50426242(CHEMBL2312346)
Affinity DataIC50: 0.450nMAssay Description:Orthosteric antagonist activity at M5 muscarinic receptor in rat striatal slices assessed as inhibition of 100 uM oxotremorine-evoked [3H]DA releaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMuscarinic acetylcholine receptor M5(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50241132(7-(3-Hydroxy-2-phenyl-propionyloxy)-9,9-dimethyl-3...)
Affinity DataIC50: 2.30nMAssay Description:Compound was evaluated for its binding affinity at human muscarinic receptor m5 by the displacement of [3H]-NMS radioligand using membranes from tran...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMuscarinic acetylcholine receptor M5(Mouse)
Johns Hopkins Medical Institutions

Curated by ChEMBL
LigandPNGBDBM50228206(Dexetimide | R-16470 [as hydrochloride])
Affinity DataIC50: 3.30nMAssay Description:Ability (10 ug/kg) to inhibit binding of [125I]iododexetimide to muscarinic receptor in miceMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMuscarinic acetylcholine receptor M5(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM81462(NSC_5572 | CAS_58947-95-8 | TRIHEXYPHENIDYL HYDROC...)
Affinity DataIC50: 10nMAssay Description:Evaluated for its binding affinity at human muscarinic receptor m5 by the displacement of [3H]NMS binding using membranes from transfected chinese ha...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMuscarinic acetylcholine receptor M5(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50606933(CHEMBL5218711)
Affinity DataIC50: 10nMAssay Description:Antagonist activity at human muscarinic M5 receptor expressed in CHO cells in the presence of acetylcholine by calcium mobilisation assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetMuscarinic acetylcholine receptor M5(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50606934(CHEMBL5218449)
Affinity DataIC50: 13nMAssay Description:Antagonist activity at human muscarinic M5 receptor expressed in CHO cells in the presence of acetylcholine by calcium mobilisation assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetMuscarinic acetylcholine receptor M5(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50609398(CHEMBL5270452)
Affinity DataIC50: 21nMAssay Description:Antagonist activity at human muscarinic M5 receptor expressed in CHO cells in the presence of acetylcholine by calcium mobilisation assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetMuscarinic acetylcholine receptor M5(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50073501(CHEMBL120119 | CHEMBL1180285 | 1-Ethyl-4-phenyl-1,...)
Affinity DataIC50: 25nMAssay Description:Displacement of [3H]NMS binding to human Muscarinic acetylcholine receptor M5 using membranes from transfected CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMuscarinic acetylcholine receptor M5(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50073501(CHEMBL120119 | CHEMBL1180285 | 1-Ethyl-4-phenyl-1,...)
Affinity DataIC50: 25nMAssay Description:Binding affinity to human M5 muscarinic receptor expressed in cell membranes by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMuscarinic acetylcholine receptor M5(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50605085(CHEMBL5204021)
Affinity DataIC50: 35nMAssay Description:Antagonist activity at human muscarinic M5 receptor expressed in CHO cells assessed as inhibition of acetylcholine-induced calcium mobilization by Fl...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetMuscarinic acetylcholine receptor M5(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50609399(CHEMBL5274311)
Affinity DataIC50: 35nMAssay Description:Antagonist activity at human muscarinic M5 receptor expressed in CHO cells in the presence of acetylcholine by calcium mobilisation assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetMuscarinic acetylcholine receptor M5(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50609398(CHEMBL5270452)
Affinity DataIC50: 35nMAssay Description:Antagonist activity at human muscarinic M5 receptor expressed in CHO cells in the presence of acetylcholine by calcium mobilisation assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetMuscarinic acetylcholine receptor M5(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50605085(CHEMBL5204021)
Affinity DataIC50: 36nMAssay Description:Antagonist activity at human muscarinic M5 receptor expressed in CHO cells in the presence of acetylcholine by calcium mobilisation assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetMuscarinic acetylcholine receptor M5(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50605085(CHEMBL5204021)
Affinity DataIC50: 36nMAssay Description:Antagonist activity at human muscarinic M5 receptor expressed in CHO cells assessed as inhibition of acetylcholine-induced calcium mobilization by Fl...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetMuscarinic acetylcholine receptor M5(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50073488(1-Ethyl-4-phenyl-1,2,3,6-tetrahydro-pyridine-3-car...)
Affinity DataIC50: 43nMAssay Description:Displacement of [3H]NMS binding to human Muscarinic acetylcholine receptor M5 using membranes from transfected CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMuscarinic acetylcholine receptor M5(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50609395(CHEMBL5277011)
Affinity DataIC50: 47nMAssay Description:Antagonist activity at human muscarinic M5 receptor expressed in CHO cells in the presence of acetylcholine by calcium mobilisation assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetMuscarinic acetylcholine receptor M5(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50073503(1-Ethyl-4-phenyl-1,2,5,6-tetrahydro-pyridine-3-car...)
Affinity DataIC50: 54nMAssay Description:Displacement of [3H]NMS binding to human Muscarinic acetylcholine receptor M5 using membranes from transfected CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMuscarinic acetylcholine receptor M5(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50073477(1-Ethyl-4-phenyl-1,2,5,6-tetrahydro-pyridine-3-car...)
Affinity DataIC50: 56nMAssay Description:Displacement of [3H]NMS binding to human Muscarinic acetylcholine receptor M5 using membranes from transfected CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMuscarinic acetylcholine receptor M5(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50073469(1-Ethyl-4-phenyl-1,2,5,6-tetrahydro-pyridine-3-car...)
Affinity DataIC50: 58nMAssay Description:Displacement of [3H]NMS binding to human Muscarinic acetylcholine receptor M5 using membranes from transfected CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMuscarinic acetylcholine receptor M5(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50606941(CHEMBL5219163)
Affinity DataIC50: 59nMAssay Description:Antagonist activity at human muscarinic M5 receptor expressed in CHO cells in the presence of acetylcholine by calcium mobilisation assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetMuscarinic acetylcholine receptor M5(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50073479(1-Ethyl-4-phenyl-1,2,3,6-tetrahydro-pyridine-3-car...)
Affinity DataIC50: 63nMAssay Description:Displacement of [3H]NMS binding to human Muscarinic acetylcholine receptor M5 using membranes from transfected CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMuscarinic acetylcholine receptor M5(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50073492(1-Ethyl-4-phenyl-1,2,5,6-tetrahydro-pyridine-3-car...)
Affinity DataIC50: 78nMAssay Description:Displacement of [3H]NMS binding to human Muscarinic acetylcholine receptor M5 using membranes from transfected CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMuscarinic acetylcholine receptor M5(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50395966(CHEMBL2164905)
Affinity DataIC50: 82nMAssay Description:Antagonist activity at human muscarinic M5 receptor by calcium mobilization assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMuscarinic acetylcholine receptor M5(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50073465(1-Ethyl-4-phenyl-1,2,5,6-tetrahydro-pyridine-3-car...)
Affinity DataIC50: 85nMAssay Description:Displacement of [3H]NMS binding to human Muscarinic acetylcholine receptor M5 using membranes from transfected CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMuscarinic acetylcholine receptor M5(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50609400(CHEMBL5274220)
Affinity DataIC50: 87nMAssay Description:Antagonist activity at human muscarinic M5 receptor expressed in CHO cells in the presence of acetylcholine by calcium mobilisation assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetMuscarinic acetylcholine receptor M5(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50605067(CHEMBL5179833)
Affinity DataIC50: 93nMAssay Description:Antagonist activity at human muscarinic M5 receptor expressed in CHO cells assessed as inhibition of acetylcholine-induced calcium mobilization by Fl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetMuscarinic acetylcholine receptor M5(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50605067(CHEMBL5179833)
Affinity DataIC50: 93nMAssay Description:Antagonist activity at human muscarinic M5 receptor expressed in CHO cells assessed as inhibition of acetylcholine-induced calcium mobilization by Fl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetMuscarinic acetylcholine receptor M5(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50605074(CHEMBL5188559)
Affinity DataIC50: 93nMAssay Description:Antagonist activity at human muscarinic M5 receptor expressed in CHO cells assessed as inhibition of acetylcholine-induced calcium mobilization by Fl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetMuscarinic acetylcholine receptor M5(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50606929(CHEMBL5218587)
Affinity DataIC50: 94nMAssay Description:Antagonist activity at human muscarinic M5 receptor expressed in CHO cells in the presence of acetylcholine by calcium mobilisation assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetMuscarinic acetylcholine receptor M5(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50605074(CHEMBL5188559)
Affinity DataIC50: 94nMAssay Description:Antagonist activity at human muscarinic M5 receptor expressed in CHO cells assessed as inhibition of acetylcholine-induced calcium mobilization by Fl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetMuscarinic acetylcholine receptor M5(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50606940(CHEMBL5218928)
Affinity DataIC50: 105nMAssay Description:Antagonist activity at human muscarinic M5 receptor expressed in CHO cells in the presence of acetylcholine by calcium mobilisation assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetMuscarinic acetylcholine receptor M5(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50606930(CHEMBL5218597)
Affinity DataIC50: 109nMAssay Description:Antagonist activity at human muscarinic M5 receptor expressed in CHO cells in the presence of acetylcholine by calcium mobilisation assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetMuscarinic acetylcholine receptor M5(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50606944(CHEMBL5219691)
Affinity DataIC50: 111nMAssay Description:Antagonist activity at human muscarinic M5 receptor expressed in CHO cells in the presence of acetylcholine by calcium mobilisation assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetMuscarinic acetylcholine receptor M5(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50606944(CHEMBL5219691)
Affinity DataIC50: 111nMAssay Description:Antagonist activity at human muscarinic M5 receptorMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetMuscarinic acetylcholine receptor M5(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50073454(1-Ethyl-4-phenyl-1,2,5,6-tetrahydro-pyridine-3-car...)
Affinity DataIC50: 115nMAssay Description:Displacement of [3H]NMS binding to human Muscarinic acetylcholine receptor M5 using membranes from transfected CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMuscarinic acetylcholine receptor M5(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50605073(CHEMBL5172903)
Affinity DataIC50: 119nMAssay Description:Antagonist activity at human muscarinic M5 receptor expressed in CHO cells assessed as inhibition of acetylcholine-induced calcium mobilization by Fl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetMuscarinic acetylcholine receptor M5(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50605073(CHEMBL5172903)
Affinity DataIC50: 120nMAssay Description:Antagonist activity at human muscarinic M5 receptor expressed in CHO cells assessed as inhibition of acetylcholine-induced calcium mobilization by Fl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetMuscarinic acetylcholine receptor M5(Rat)
University of Arkansas For Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50605085(CHEMBL5204021)
Affinity DataIC50: 125nMAssay Description:Antagonist activity at rat muscarinic M5 receptorMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetMuscarinic acetylcholine receptor M5(Rat)
University of Arkansas For Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50028290(cis-2-Methyl-7-phenyl-1,3,4,6,7,11b-hexahydro-2H-p...)
Affinity DataIC50: 130nMAssay Description:Binding affinity towards muscarinic acetylcholine receptor by inhibiting specific binding of [3H]quinuclidinyl benzilate (0.8 nM) in vitro to membran...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMuscarinic acetylcholine receptor M5(Rat)
University of Arkansas For Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50028290(cis-2-Methyl-7-phenyl-1,3,4,6,7,11b-hexahydro-2H-p...)
Affinity DataIC50: 130nMAssay Description:Binding affinity towards muscarinic acetylcholine receptor by inhibiting specific binding of [3H]quinuclidinyl benzilate (0.8 nM) in vitro to membran...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMuscarinic acetylcholine receptor M5(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50606928(CHEMBL5220906)
Affinity DataIC50: 134nMAssay Description:Antagonist activity at human muscarinic M5 receptor expressed in CHO cells in the presence of acetylcholine by calcium mobilisation assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetMuscarinic acetylcholine receptor M5(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50073464(1-Ethyl-4-phenyl-1,2,5,6-tetrahydro-pyridine-3-car...)
Affinity DataIC50: 139nMAssay Description:Displacement of [3H]NMS binding to human Muscarinic acetylcholine receptor M5 using membranes from transfected CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMuscarinic acetylcholine receptor M5(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50606936(CHEMBL5218709)
Affinity DataIC50: 143nMAssay Description:Antagonist activity at human muscarinic M5 receptor expressed in CHO cells in the presence of acetylcholine by calcium mobilisation assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetMuscarinic acetylcholine receptor M5(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50605077(CHEMBL5209198)
Affinity DataIC50: 148nMAssay Description:Antagonist activity at human muscarinic M5 receptor expressed in CHO cells assessed as inhibition of acetylcholine-induced calcium mobilization by Fl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetMuscarinic acetylcholine receptor M5(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50605077(CHEMBL5209198)
Affinity DataIC50: 149nMAssay Description:Antagonist activity at human muscarinic M5 receptor expressed in CHO cells assessed as inhibition of acetylcholine-induced calcium mobilization by Fl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
Displayed 1 to 50 (of 440 total ) | Next | Last >>
Jump to: